Herve Vaucheret

Summary

Affiliation: Institut National de la Recherche Agronomique
Country: France

Publications

  1. ncbi request reprint Post-transcriptional gene silencing in plants
    H Vaucheret
    Laboratoire de Biologie Cellulaire, INRA, Versailles 78026, France
    J Cell Sci 114:3083-91. 2001
  2. pmc The origin and effect of small RNA signaling in plants
    Jean Sébastien Parent
    Institut Jean Pierre Bourgin, UMR1318, INRA Versailles, France
    Front Plant Sci 3:179. 2012
  3. pmc RDR2 partially antagonizes the production of RDR6-dependent siRNA in sense transgene-mediated PTGS
    Vincent Jauvion
    Institut Jean Pierre Bourgin, INRA, Versailles, France
    PLoS ONE 7:e29785. 2012
  4. pmc AGO1 and AGO2 act redundantly in miR408-mediated Plantacyanin regulation
    Nicolas Maunoury
    Institut Jean Pierre Bourgin, INRA, Versailles, France
    PLoS ONE 6:e28729. 2011
  5. pmc The miRNA pathway limits AGO1 availability during siRNA-mediated PTGS defense against exogenous RNA
    Angel Emilio Martinez de Alba
    Institut Jean Pierre Bourgin, UMR1318, INRA, 78026 Versailles Cedex, France
    Nucleic Acids Res 39:9339-44. 2011
  6. ncbi request reprint MicroRNA-dependent trans-acting siRNA production
    Herve Vaucheret
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, INRA 78026 Versailles Cedex, France
    Sci STKE 2005:pe43. 2005
  7. ncbi request reprint Post-transcriptional small RNA pathways in plants: mechanisms and regulations
    Herve Vaucheret
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, l Institut National de la Recherche Agronomique, 78026 Versailles Cedex, France
    Genes Dev 20:759-71. 2006
  8. pmc The action of ARGONAUTE1 in the miRNA pathway and its regulation by the miRNA pathway are crucial for plant development
    Herve Vaucheret
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, INRA, 78026 Versailles Cedex, France
    Genes Dev 18:1187-97. 2004
  9. doi request reprint Plant ARGONAUTES
    Herve Vaucheret
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique INRA, 78026 Versailles Cedex, France
    Trends Plant Sci 13:350-8. 2008
  10. pmc AGO1 homeostasis involves differential production of 21-nt and 22-nt miR168 species by MIR168a and MIR168b
    Herve Vaucheret
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, INRA, Versailles, France
    PLoS ONE 4:e6442. 2009

Collaborators

  • J C Palauqui
  • Taline Elmayan
  • Allison C Mallory
  • Franck Vazquez
  • Matthew R Tucker
  • Christian Godon
  • Karin Ljung
  • Jun Liu
  • Thomas Laux
  • Nicolas Bouche
  • C Beclin
  • Xuemei Chen
  • Alexis Maizel
  • J P Nap
  • Angel Emilio Martinez de Alba
  • Vincent Jauvion
  • Nathalie Bouteiller
  • Virginie Gasciolli
  • Jean Benoit Morel
  • Stéphanie Boutet
  • Philippe Mourrain
  • Ana Beatriz Moreno
  • Jean Sébastien Parent
  • Ivan Le Masson
  • Maud Rivard
  • Nicolas Maunoury
  • Isabelle Gy
  • Dominique Lauressergues
  • Xavier Adenot
  • Céline Sorin
  • Florence Proux
  • Emilie Elvira-Matelot
  • Martin D Crespi
  • Florian Bardou
  • M Fagard
  • J B Morel
  • P Mourrain
  • Rik van Blokland
  • Caroline Proux
  • Julie Gombert
  • Jan M Kooter
  • Gaia Geiss
  • Christophe Garcion
  • Mariusz Kowalczyk
  • Goran Sandberg
  • David P Bartel
  • John D Bussell
  • Isabelle Camus
  • Catherine Bellini
  • Heather McKhann
  • Ariane Gratias
  • Patrice Crété
  • Mathilde Fagard
  • Frank Feuerbach
  • D Jouette
  • M Sanial
  • A M Lacombe
  • F Feuerbach
  • K Rémoué
  • T A Vo
  • S Boutet
  • C Bellini
  • S Nikic
  • N Picault

Detail Information

Publications37

  1. ncbi request reprint Post-transcriptional gene silencing in plants
    H Vaucheret
    Laboratoire de Biologie Cellulaire, INRA, Versailles 78026, France
    J Cell Sci 114:3083-91. 2001
    ..Whether viruses can counteract RNAi in animals and whether endogenous suppressors of RNAi exist in animals is still unknown...
  2. pmc The origin and effect of small RNA signaling in plants
    Jean Sébastien Parent
    Institut Jean Pierre Bourgin, UMR1318, INRA Versailles, France
    Front Plant Sci 3:179. 2012
    ..We also review the various genetic requirements needed for production, movement and perception of the silencing signal...
  3. pmc RDR2 partially antagonizes the production of RDR6-dependent siRNA in sense transgene-mediated PTGS
    Vincent Jauvion
    Institut Jean Pierre Bourgin, INRA, Versailles, France
    PLoS ONE 7:e29785. 2012
    ....
  4. pmc AGO1 and AGO2 act redundantly in miR408-mediated Plantacyanin regulation
    Nicolas Maunoury
    Institut Jean Pierre Bourgin, INRA, Versailles, France
    PLoS ONE 6:e28729. 2011
    ..In contrast, AGO2 has only been implicated in antibacterial defense in association with miR393*, which has a 5'A. AGO2 also participates in antiviral defense in association with viral siRNAs...
  5. pmc The miRNA pathway limits AGO1 availability during siRNA-mediated PTGS defense against exogenous RNA
    Angel Emilio Martinez de Alba
    Institut Jean Pierre Bourgin, UMR1318, INRA, 78026 Versailles Cedex, France
    Nucleic Acids Res 39:9339-44. 2011
    ..We suggest that the miRNA pathway imposes an important limitation on PTGS efficiency, which could help protect endogenous mRNAs from being routinely targeted by PTGS...
  6. ncbi request reprint MicroRNA-dependent trans-acting siRNA production
    Herve Vaucheret
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, INRA 78026 Versailles Cedex, France
    Sci STKE 2005:pe43. 2005
    ..Some of the tasiRNA targets probably regulate the juvenile-to-adult phase transition, but the roles of other tasiRNA targets remain to be determined...
  7. ncbi request reprint Post-transcriptional small RNA pathways in plants: mechanisms and regulations
    Herve Vaucheret
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, l Institut National de la Recherche Agronomique, 78026 Versailles Cedex, France
    Genes Dev 20:759-71. 2006
    ..This review focuses on the various types of post-transcriptional small RNA-directed pathways in plants, describing their roles and their regulations...
  8. pmc The action of ARGONAUTE1 in the miRNA pathway and its regulation by the miRNA pathway are crucial for plant development
    Herve Vaucheret
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, INRA, 78026 Versailles Cedex, France
    Genes Dev 18:1187-97. 2004
    ....
  9. doi request reprint Plant ARGONAUTES
    Herve Vaucheret
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique INRA, 78026 Versailles Cedex, France
    Trends Plant Sci 13:350-8. 2008
    ....
  10. pmc AGO1 homeostasis involves differential production of 21-nt and 22-nt miR168 species by MIR168a and MIR168b
    Herve Vaucheret
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, INRA, Versailles, France
    PLoS ONE 4:e6442. 2009
    ..AGO1 homeostasis entails DCL1-dependent production of miR168 from MIR168a and MIR168b transcripts, post-transcriptional stabilization of miR168 by AGO1, and AGO1-catalyzed miR168-guided cleavage of AGO1 mRNA...
  11. pmc AGO1 homeostasis entails coexpression of MIR168 and AGO1 and preferential stabilization of miR168 by AGO1
    Herve Vaucheret
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, INRA, 78026 Versailles Cedex, France
    Mol Cell 22:129-36. 2006
    ..We suggest that miR168 stabilization occurs at the level of silencing-complex assembly and that modulating the efficiency of assembling miRNA-programmed silencing complexes will also be important in other contexts...
  12. ncbi request reprint Arabidopsis HEN1: a genetic link between endogenous miRNA controlling development and siRNA controlling transgene silencing and virus resistance
    Stéphanie Boutet
    Laboratoire de Biologie Cellulaire, INRA, 78026 Versailles Cedex, France
    Curr Biol 13:843-8. 2003
    ....
  13. pmc Redundant and specific roles of the ARGONAUTE proteins AGO1 and ZLL in development and small RNA-directed gene silencing
    Allison C Mallory
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, INRA, Versailles Cedex, France
    PLoS Genet 5:e1000646. 2009
    ....
  14. pmc Arabidopsis FIERY1, XRN2, and XRN3 are endogenous RNA silencing suppressors
    Isabelle Gy
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique INRA, 78026 Versailles Cedex, France
    Plant Cell 19:3451-61. 2007
    ..We anticipate that screens incorporating partially compromised silencing components will uncover additional PTGS suppressors that may not be revealed using robust silencing systems...
  15. ncbi request reprint DRB4-dependent TAS3 trans-acting siRNAs control leaf morphology through AGO7
    Xavier Adenot
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique, 78026 Versailles Cedex, France
    Curr Biol 16:927-32. 2006
    ....
  16. ncbi request reprint A branched pathway for transgene-induced RNA silencing in plants
    Christophe Beclin
    Laboratoire de Biologie Cellulaire, INRA, 78026 Cedex, Versailles, France
    Curr Biol 12:684-8. 2002
    ..Moreover, transgene methylation would result from production or action of dsRNA, since it does not require SGS2/SDE1, SGS3, and AGO1...
  17. pmc ARGONAUTE 1 homeostasis invokes the coordinate action of the microRNA and siRNA pathways
    Allison C Mallory
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, INRA, Route de Saint Cyr, 78026 Versailles, France
    EMBO Rep 10:521-6. 2009
    ....
  18. pmc An antagonistic function for Arabidopsis DCL2 in development and a new function for DCL4 in generating viral siRNAs
    Nicolas Bouche
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, INRA, Versailles, France
    EMBO J 25:3347-56. 2006
    ..Given the complexity of the small RNA repertoire in plants, the implication of each DCL, in particular DCL2, in the production of small RNAs that have no known function will constitute one of the next challenges...
  19. pmc Mutations in the Arabidopsis H3K4me2/3 demethylase JMJ14 suppress posttranscriptional gene silencing by decreasing transgene transcription
    Ivan Le Masson
    Institut Jean Pierre Bourgin, Unité Mixte de Recherche 1318, Institut National de la Recherche Agronomique INRA, 78000 Versailles, France
    Plant Cell 24:3603-12. 2012
    ..Removing JMJ14 likely allows other H3K4 demethylases encoded by the Arabidopsis thaliana genome to act on transgenes and reduce transcription levels, thus preventing the triggering of S-PTGS...
  20. doi request reprint A neomorphic sgs3 allele stabilizing miRNA cleavage products reveals that SGS3 acts as a homodimer
    Taline Elmayan
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, INRA, Versaille, France
    FEBS J 276:835-44. 2009
    ....
  21. ncbi request reprint Arabidopsis RPA2: a genetic link among transcriptional gene silencing, DNA repair, and DNA replication
    Taline Elmayan
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique, 78026 Versailles Cedex, France
    Curr Biol 15:1919-25. 2005
    ..These results suggest a coordination of the TGS machinery with DNA replication, repair, or recombination machinery at some loci, and they emphasize the diversification of the TGS pathway...
  22. pmc Fertile hypomorphic ARGONAUTE (ago1) mutants impaired in post-transcriptional gene silencing and virus resistance
    Jean Benoit Morel
    Laboratoire de Biologie Cellulaire, Institut National de la Recherche Agronomique, 78026 Versailles Cedex, France
    Plant Cell 14:629-39. 2002
    ..Finally, we show that hypomorphic ago1 mutants are hypersensitive to virus infection, confirming the hypothesis that in plants PTGS is a mechanism of defense against viruses...
  23. ncbi request reprint The nuclear dsRNA binding protein HYL1 is required for microRNA accumulation and plant development, but not posttranscriptional transgene silencing
    Franck Vazquez
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, INRA, 78026 Versailles Cedex, France
    Curr Biol 14:346-51. 2004
    ..elegans and Drosophila, respectively...
  24. ncbi request reprint Partially redundant functions of Arabidopsis DICER-like enzymes and a role for DCL4 in producing trans-acting siRNAs
    Virginie Gasciolli
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique, 78026 Versailles Cedex, France
    Curr Biol 15:1494-500. 2005
    ....
  25. ncbi request reprint A single transgene locus triggers both transcriptional and post-transcriptional silencing through double-stranded RNA production
    Philippe Mourrain
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, INRA, 78026, Versailles Cedex, France
    Planta 225:365-79. 2007
    ..In contrast, we contribute local and systemic trafficking of silencing signals and sensitivity to viruses to the cytoplasmic steps of PTGS and to amplification steps that require high levels of target mRNAs...
  26. doi request reprint MicroRNA maturation and action--the expanding roles of ARGONAUTEs
    Allison C Mallory
    Laboratoire de Biologie Cellulaire, Institut Jean Pierre Bourgin, INRA, 78026 Versailles Cedex, France
    Curr Opin Plant Biol 11:560-6. 2008
    ..Our expanding appreciation of miRNA-directed regulation during plant development and stress adaptations has placed miRNAs at the forefront of plant biology...
  27. pmc Cytoplasmic and nuclear quality control and turnover of single-stranded RNA modulate post-transcriptional gene silencing in plants
    Ana Beatriz Moreno
    Institut des Sciences du Vegetal, CNRS UPR 2355, SPS Saclay Plant Sciences, 91198 Gif sur Yvette, France
    Nucleic Acids Res 41:4699-708. 2013
    ..We propose a model of single-stranded RNA tug-of-war between RQC and S-PTGS that ensures the correct partitioning of RNA substrates among these RNA degradation pathways...
  28. pmc Auxin and light control of adventitious rooting in Arabidopsis require ARGONAUTE1
    Céline Sorin
    Laboratoire de Biologie Cellulaire, Institut National de la Recherche Agronomique, 78026 Versailles Cedex, France
    Plant Cell 17:1343-59. 2005
    ..These results suggest that ARF17 could be a major regulator of adventitious rooting in Arabidopsis...
  29. pmc The conserved RNA trafficking proteins HPR1 and TEX1 are involved in the production of endogenous and exogenous small interfering RNA in Arabidopsis
    Vincent Jauvion
    Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique, 78026 Versailles Cedex, France
    Plant Cell 22:2697-709. 2010
    ..We propose that both HPR1 and TEX1 participate in the trafficking of siRNA precursors to the ARGONAUTE catalytic center...
  30. ncbi request reprint Molecular cloning and characterisation of the two homologous genes coding for nitrate reductase in tobacco
    H Vaucheret
    Laboratoire de Biologie Cellulaire, INRA Centre de Versailles, France
    Mol Gen Genet 216:10-5. 1989
    ..The remaining N-terminal part of the protein should thus carry the catalytic site of nitrate reduction by the molybdenum cofactor...
  31. doi request reprint Gene silencing in plants: a diversity of pathways
    Angel Emilio Martinez de Alba
    Institut Jean Pierre Bourgin, UMR 1318, INRA, Route de St Cyr, 78000 Versailles, France
    Biochim Biophys Acta 1829:1300-8. 2013
    ..This review covers the diversity of RNA silencing pathways identified in plants. ..
  32. ncbi request reprint Transcriptional gene silencing in plants: targets, inducers and regulators
    H Vaucheret
    Laboratoire de Biologie Cellulaire, INRA, 78026, Versailles Cedex, France
    Trends Genet 17:29-35. 2001
    ..TGS and PTGS, therefore, appear to form two alternative pathways to control incoming, redundant and/or mobile nucleic acids...
  33. pmc AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals
    M Fagard
    Laboratoire de Biologie Cellulaire, Institut National de la Recherche Agronomique, 78026 Versailles Cedex, France
    Proc Natl Acad Sci U S A 97:11650-4. 2000
    ..These results raise the possibility that PTGS, or at least some of its elements, could participate in the regulation of gene expression during development in plants...
  34. ncbi request reprint Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance
    P Mourrain
    Laboratoire de Biologie Cellulaire, Institut National de la Recherche Agronomique, Versailles, France
    Cell 101:533-42. 2000
    ..Both sgs2 and sgs3 mutants show enhanced susceptibility to virus, definitively proving that PTGS is an antiviral defense mechanism that can also target transgene RNA for degradation...
  35. ncbi request reprint Infection of tobacco or Arabidopsis plants by CMV counteracts systemic post-transcriptional silencing of nonviral (trans)genes
    C Beclin
    Laboratoire de Biologie Cellulaire, INRA Versailles, Versailles Cedex, 78026, France
    Virology 252:313-7. 1998
    ....
  36. ncbi request reprint Flank matrix attachment regions (MARs) from chicken, bean, yeast or tobacco do not prevent homology-dependent trans-silencing in transgenic tobacco plants
    H Vaucheret
    Laboratoire de Biologie Cellulaire, INRA, Versailles, France
    Mol Gen Genet 259:388-92. 1998
    ..These results therefore demonstrate that MARs are not able to protect transgene expression from strong silencing loci that act in trans...
  37. pmc Form, function, and regulation of ARGONAUTE proteins
    Allison Mallory
    Institut Jean Pierre Bourgin, Unité Mixte de Recherche 1318, Institut National de la Recherche Agronomique, 78026 Versailles Cedex, France
    Plant Cell 22:3879-89. 2010
    ..In this review, we present general features of plant and animal AGO proteins and detail our knowledge on the 10 Arabidopsis thaliana AGOs...