Guy TranVan Nhieu

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. ncbi request reprint Mechanism of Shigella entry into epithelial cells
    G T Nhieu
    Unité de Pathogénie Microbienne Moléculaire INSERM U389 Institut Pasteur 28 rue du Dr Roux 75724 Paris Cedex 15 France
    Curr Opin Microbiol 2:51-5. 1999
  2. pmc IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells
    G Tran Van Nhieu
    Unité de Pathogénie Microbienne Moléculaire INSERM U389, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    EMBO J 18:3249-62. 1999
  3. ncbi request reprint Bacterial signals and cell responses during Shigella entry into epithelial cells
    G Tran Van Nhieu
    Unite de Pathogenie Microbienne Moleculaire, INSERM U389, Institut Pasteur, Paris, France
    Cell Microbiol 2:187-93. 2000
  4. ncbi request reprint Calcium signalling during cell interactions with bacterial pathogens
    Guy TranVan Nhieu
    Unite de Pathogenie Microbienne Moleculaire, INSERM U389, Institut Pasteur, 75724 Paris Cedex 15, France
    Biol Cell 96:93-101. 2004
  5. pmc Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells
    Laurence Bougnères
    Unite de Pathogenie Microbienne Moleculaire, INSERM U389, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    J Cell Biol 166:225-35. 2004
  6. pmc Modulation of bacterial entry into epithelial cells by association between vinculin and the Shigella IpaA invasin
    G Tran Van Nhieu
    Unite de Pathogenie Microbienne Moleculaire, INSERM U389, Institut Pasteur, Paris, France
    EMBO J 16:2717-29. 1997
  7. ncbi request reprint Rupture of the intestinal epithelial barrier and mucosal invasion by Shigella flexneri
    P J Sansonetti
    Unite de Pathogenie Microbienne Moleculaire, Institut National de la Sante et de la Recherche Medicale, Institut Pasteur, Paris, France
    Clin Infect Dis 28:466-75. 1999
  8. ncbi request reprint The development of a FACS-based strategy for the isolation of Shigella flexneri mutants that are deficient in intercellular spread
    M Rathman
    Unite de Pathogenie Microbienne Moleculaire, INSERM U389, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Mol Microbiol 35:974-90. 2000

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Mechanism of Shigella entry into epithelial cells
    G T Nhieu
    Unité de Pathogénie Microbienne Moléculaire INSERM U389 Institut Pasteur 28 rue du Dr Roux 75724 Paris Cedex 15 France
    Curr Opin Microbiol 2:51-5. 1999
    ..Actin polymerization at the site of entry is dependent on the IpaB and IpaC proteins, whereas IpaA further modulates cytoskeletal rearrangements by binding to vinculin...
  2. pmc IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells
    G Tran Van Nhieu
    Unité de Pathogénie Microbienne Moléculaire INSERM U389, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    EMBO J 18:3249-62. 1999
    ..We conclude that IpaC leads to activation of Cdc42 which in turn, causes activation of Rac, both GTPases being required for Shigella entry...
  3. ncbi request reprint Bacterial signals and cell responses during Shigella entry into epithelial cells
    G Tran Van Nhieu
    Unite de Pathogenie Microbienne Moleculaire, INSERM U389, Institut Pasteur, Paris, France
    Cell Microbiol 2:187-93. 2000
    ..The Src tyrosine kinase activity, which is required for Shigella-induced actin polymerization, also appears to be involved in a negative regulatory loop that downregulates Rho at the site of entry...
  4. ncbi request reprint Calcium signalling during cell interactions with bacterial pathogens
    Guy TranVan Nhieu
    Unite de Pathogenie Microbienne Moleculaire, INSERM U389, Institut Pasteur, 75724 Paris Cedex 15, France
    Biol Cell 96:93-101. 2004
    ....
  5. pmc Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells
    Laurence Bougnères
    Unite de Pathogenie Microbienne Moleculaire, INSERM U389, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    J Cell Biol 166:225-35. 2004
    ..These results point at a major role for a Crk-cortactin complex in actin polymerization downstream of tyrosine kinase signaling...
  6. pmc Modulation of bacterial entry into epithelial cells by association between vinculin and the Shigella IpaA invasin
    G Tran Van Nhieu
    Unite de Pathogenie Microbienne Moleculaire, INSERM U389, Institut Pasteur, Paris, France
    EMBO J 16:2717-29. 1997
    ..Presumably, IpaA-vinculin interaction initiates the formation of focal adhesion-like structures required for efficient invasion...
  7. ncbi request reprint Rupture of the intestinal epithelial barrier and mucosal invasion by Shigella flexneri
    P J Sansonetti
    Unite de Pathogenie Microbienne Moleculaire, Institut National de la Sante et de la Recherche Medicale, Institut Pasteur, Paris, France
    Clin Infect Dis 28:466-75. 1999
    ..Once they are intracellular, bacteria multiply within the cytoplasm and move from cell to cell by an actin-dependent process...
  8. ncbi request reprint The development of a FACS-based strategy for the isolation of Shigella flexneri mutants that are deficient in intercellular spread
    M Rathman
    Unite de Pathogenie Microbienne Moleculaire, INSERM U389, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Mol Microbiol 35:974-90. 2000
    ....