Eliette Touati

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. ncbi Chronic Helicobacter pylori infections induce gastric mutations in mice
    Eliette Touati
    Unité de Programmation Moléculaire et de Toxicologie Génétique, Institut Pasteur, Paris, France
    Gastroenterology 124:1408-19. 2003
  2. doi When bacteria become mutagenic and carcinogenic: lessons from H. pylori
    Eliette Touati
    Institut Pasteur, Unité de Pathogenèse de Helicobacter, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Mutat Res 703:66-70. 2010
  3. ncbi Deficiency in OGG1 protects against inflammation and mutagenic effects associated with H. pylori infection in mouse
    Eliette Touati
    Unité de Pathogénie Bactérienne des Muqueuses, Institut Pasteur, Paris, France
    Helicobacter 11:494-505. 2006
  4. doi H. pylori-induced promoter hypermethylation downregulates USF1 and USF2 transcription factor gene expression
    Francoise I Bussiere
    Institut Pasteur, Unité de Pathogenèse de Helicobacter, Paris, France
    Cell Microbiol 12:1124-33. 2010
  5. ncbi Genotoxicity of 2-nitro-7-methoxy-naphtho[2,1-b]furan (R7000): a case study with some considerations on nitrofurantoin and nifuroxazide
    Maurice Hofnung
    Unité de Programmation Moléculaire et de Toxicologie Génétique, CNRS URA 1444, Institut Pasteur, Paris, France
    Res Microbiol 153:427-34. 2002
  6. ncbi Anti-Helicobacter pylori activities of natural isopentenyloxycinnamyl derivatives from Boronia pinnata
    Cécile Ribeiro da Silva
    Unit ofHelicobacter Pathogenesis, Department ofMicrobiology, Institut Pasteur, 75724 Paris Cedex 15, France
    Nat Prod Commun 7:1347-50. 2012
  7. ncbi Comparison of kinetics of induction of DNA adducts and gene mutations by a nitrofuran compound, 7-methoxy-2-nitronaphtho[2,1-b]furan (R7000), in the caecum and small intestine of Big Blue mice
    Xavier Arrault
    Unité de Programmation Moléculaire et de Toxicologie Génétique, CNRS URA 1444, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris Cedex 15, France
    Mutagenesis 17:353-9. 2002
  8. ncbi Organ-targeted mutagenicity of nitrofurantoin in Big Blue transgenic mice
    Philippe Quillardet
    Unité des Cyanobactéries, Institut Pasteur 28, rue du Dr Roux, 75724 Paris Cedex15, France
    Mutagenesis 21:305-11. 2006

Collaborators

Detail Information

Publications8

  1. ncbi Chronic Helicobacter pylori infections induce gastric mutations in mice
    Eliette Touati
    Unité de Programmation Moléculaire et de Toxicologie Génétique, Institut Pasteur, Paris, France
    Gastroenterology 124:1408-19. 2003
    ..The aim of this study was to analyze the role of H. pylori infections in the induction of mutagenic events in gastric epithelial cells. The effect of a high-salt diet as a genotoxic risk factor was also investigated...
  2. doi When bacteria become mutagenic and carcinogenic: lessons from H. pylori
    Eliette Touati
    Institut Pasteur, Unité de Pathogenèse de Helicobacter, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Mutat Res 703:66-70. 2010
    ..pylori infection...
  3. ncbi Deficiency in OGG1 protects against inflammation and mutagenic effects associated with H. pylori infection in mouse
    Eliette Touati
    Unité de Pathogénie Bactérienne des Muqueuses, Institut Pasteur, Paris, France
    Helicobacter 11:494-505. 2006
    ..The present work investigates the consequences of a deficiency in the OGG1 DNA glycosylase, responsible for the excision of 8-oxo guanine, on the inflammatory and genotoxic host response to the infection...
  4. doi H. pylori-induced promoter hypermethylation downregulates USF1 and USF2 transcription factor gene expression
    Francoise I Bussiere
    Institut Pasteur, Unité de Pathogenèse de Helicobacter, Paris, France
    Cell Microbiol 12:1124-33. 2010
    ..These mechanisms occurred in the context of metaplastic lesions, suggesting that alteration of USF1 and USF2 levels could participate in the promotion of neoplastic process during H. pylori infection...
  5. ncbi Genotoxicity of 2-nitro-7-methoxy-naphtho[2,1-b]furan (R7000): a case study with some considerations on nitrofurantoin and nifuroxazide
    Maurice Hofnung
    Unité de Programmation Moléculaire et de Toxicologie Génétique, CNRS URA 1444, Institut Pasteur, Paris, France
    Res Microbiol 153:427-34. 2002
    ..In the present paper, we review essential data on the genotoxicity of R7000 and briefly discuss the case of nitrofurantoin and nifuroxazide, two nitrofurans, still in use as urinary and gastrointestinal disinfectants...
  6. ncbi Anti-Helicobacter pylori activities of natural isopentenyloxycinnamyl derivatives from Boronia pinnata
    Cécile Ribeiro da Silva
    Unit ofHelicobacter Pathogenesis, Department ofMicrobiology, Institut Pasteur, 75724 Paris Cedex 15, France
    Nat Prod Commun 7:1347-50. 2012
    ..These data indicate that these natural isopentenyloxycinnamyl derivatives related to boropinic acid can be considered as novel antibacterial agents with anti-H. pylori activity...
  7. ncbi Comparison of kinetics of induction of DNA adducts and gene mutations by a nitrofuran compound, 7-methoxy-2-nitronaphtho[2,1-b]furan (R7000), in the caecum and small intestine of Big Blue mice
    Xavier Arrault
    Unité de Programmation Moléculaire et de Toxicologie Génétique, CNRS URA 1444, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris Cedex 15, France
    Mutagenesis 17:353-9. 2002
    ..Some discrepancies in the R7000 genotoxic effects between the two organs were observed, which may be attributable to differences in the metabolic activation pathway of the compound, as well as to DNA repair proficiency in each tissue...
  8. ncbi Organ-targeted mutagenicity of nitrofurantoin in Big Blue transgenic mice
    Philippe Quillardet
    Unité des Cyanobactéries, Institut Pasteur 28, rue du Dr Roux, 75724 Paris Cedex15, France
    Mutagenesis 21:305-11. 2006
    ..These data are relevant to the targeted action of nitrofurantoin as a urinary antimicrobial agent. No significant increase of mutants was detected in the case of nifuroxazide-treated mice whatever the organs analysed...