Jean Michel Thiberge

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. pmc From array-based hybridization of Helicobacter pylori isolates to the complete genome sequence of an isolate associated with MALT lymphoma
    Jean Michel Thiberge
    Institut Pasteur, Unité postulante de Pathogenèse de Helicobacter, Paris, France
    BMC Genomics 11:368. 2010
  2. ncbi request reprint Responsiveness to acidity via metal ion regulators mediates virulence in the gastric pathogen Helicobacter pylori
    Stéphanie Bury-Moné
    Institut Pasteur, Unité de Pathogénie Bactérienne des Muqueuses, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Mol Microbiol 53:623-38. 2004
  3. pmc Presence of active aliphatic amidases in Helicobacter species able to colonize the stomach
    Stéphanie Bury-Moné
    Unité de Pathogénie Bactérienne des Muqueuses, Département de Pathogenèse Microbienne Département Structure et Dynamique des Génomes, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Infect Immun 71:5613-22. 2003
  4. ncbi request reprint Chronic Helicobacter pylori infections induce gastric mutations in mice
    Eliette Touati
    Unité de Programmation Moléculaire et de Toxicologie Génétique, Institut Pasteur, Paris, France
    Gastroenterology 124:1408-19. 2003
  5. ncbi request reprint Characterization of the roles of NikR, a nickel-responsive pleiotropic autoregulator of Helicobacter pylori
    Monica Contreras
    Unité de Pathogénie Bactérienne des Muqueuses, Institut Pasteur, 75724 Paris 15, France
    Mol Microbiol 49:947-63. 2003
  6. ncbi request reprint Deficiency in OGG1 protects against inflammation and mutagenic effects associated with H. pylori infection in mouse
    Eliette Touati
    Unité de Pathogénie Bactérienne des Muqueuses, Institut Pasteur, Paris, France
    Helicobacter 11:494-505. 2006
  7. pmc Roles of alpha and beta carbonic anhydrases of Helicobacter pylori in the urease-dependent response to acidity and in colonization of the murine gastric mucosa
    Stéphanie Bury-Moné
    Unité de Pathogénie Bactérienne des Muqueuses, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Infect Immun 76:497-509. 2008
  8. pmc Host alternation is necessary to maintain the genome stability of rift valley fever virus
    Sara Moutailler
    Molecular Genetics of Bunyavirus, Department of Virology, Institut Pasteur, Paris, France
    PLoS Negl Trop Dis 5:e1156. 2011
  9. pmc Trans-translation in Helicobacter pylori: essentiality of ribosome rescue and requirement of protein tagging for stress resistance and competence
    Marie Thibonnier
    Institut Pasteur, Unité postulante de Pathogenèse de Helicobacter, Paris, France
    PLoS ONE 3:e3810. 2008
  10. pmc Multilocus sequence typing and rtxA toxin gene sequencing analysis of Kingella kingae isolates demonstrates genetic diversity and international clones
    Romain Basmaci
    Univ Paris Diderot, Sorbonne Paris Cité, EA 3105, Paris, France
    PLoS ONE 7:e38078. 2012

Collaborators

Detail Information

Publications13

  1. pmc From array-based hybridization of Helicobacter pylori isolates to the complete genome sequence of an isolate associated with MALT lymphoma
    Jean Michel Thiberge
    Institut Pasteur, Unité postulante de Pathogenèse de Helicobacter, Paris, France
    BMC Genomics 11:368. 2010
    ..To determine whether certain combinations of genetic markers can be used to predict the clinical source of the infection, we analyzed well documented and geographically homogenous clinical isolates using a comparative genomics approach...
  2. ncbi request reprint Responsiveness to acidity via metal ion regulators mediates virulence in the gastric pathogen Helicobacter pylori
    Stéphanie Bury-Moné
    Institut Pasteur, Unité de Pathogénie Bactérienne des Muqueuses, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Mol Microbiol 53:623-38. 2004
    ..pylori acid response. Finally, a nikR-fur mutant is attenuated in the mouse model, emphasizing the link between response to acidity, metal metabolism and virulence in this gastric pathogen...
  3. pmc Presence of active aliphatic amidases in Helicobacter species able to colonize the stomach
    Stéphanie Bury-Moné
    Unité de Pathogénie Bactérienne des Muqueuses, Département de Pathogenèse Microbienne Département Structure et Dynamique des Génomes, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Infect Immun 71:5613-22. 2003
    ..Since amidases are found only in Helicobacter species able to colonize the stomach, their acquisition might be related to selective pressure in this particular gastric environment...
  4. ncbi request reprint Chronic Helicobacter pylori infections induce gastric mutations in mice
    Eliette Touati
    Unité de Programmation Moléculaire et de Toxicologie Génétique, Institut Pasteur, Paris, France
    Gastroenterology 124:1408-19. 2003
    ..The aim of this study was to analyze the role of H. pylori infections in the induction of mutagenic events in gastric epithelial cells. The effect of a high-salt diet as a genotoxic risk factor was also investigated...
  5. ncbi request reprint Characterization of the roles of NikR, a nickel-responsive pleiotropic autoregulator of Helicobacter pylori
    Monica Contreras
    Unité de Pathogénie Bactérienne des Muqueuses, Institut Pasteur, 75724 Paris 15, France
    Mol Microbiol 49:947-63. 2003
    ..Thus, as previously suggested for Fur in H. pylori, NikR appears to be a global regulator of the metabolism of some divalent cations within a highly complex regulated network...
  6. ncbi request reprint Deficiency in OGG1 protects against inflammation and mutagenic effects associated with H. pylori infection in mouse
    Eliette Touati
    Unité de Pathogénie Bactérienne des Muqueuses, Institut Pasteur, Paris, France
    Helicobacter 11:494-505. 2006
    ..The present work investigates the consequences of a deficiency in the OGG1 DNA glycosylase, responsible for the excision of 8-oxo guanine, on the inflammatory and genotoxic host response to the infection...
  7. pmc Roles of alpha and beta carbonic anhydrases of Helicobacter pylori in the urease-dependent response to acidity and in colonization of the murine gastric mucosa
    Stéphanie Bury-Moné
    Unité de Pathogénie Bactérienne des Muqueuses, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Infect Immun 76:497-509. 2008
    ..In conclusion, CA contribute to the urease-dependent response to acidity of H. pylori and are required for high-grade inflammation and efficient colonization by some strains...
  8. pmc Host alternation is necessary to maintain the genome stability of rift valley fever virus
    Sara Moutailler
    Molecular Genetics of Bunyavirus, Department of Virology, Institut Pasteur, Paris, France
    PLoS Negl Trop Dis 5:e1156. 2011
    ....
  9. pmc Trans-translation in Helicobacter pylori: essentiality of ribosome rescue and requirement of protein tagging for stress resistance and competence
    Marie Thibonnier
    Institut Pasteur, Unité postulante de Pathogenèse de Helicobacter, Paris, France
    PLoS ONE 3:e3810. 2008
    ..Helicobacter pylori is a pathogen persistently colonizing a hostile niche, the stomach of humans...
  10. pmc Multilocus sequence typing and rtxA toxin gene sequencing analysis of Kingella kingae isolates demonstrates genetic diversity and international clones
    Romain Basmaci
    Univ Paris Diderot, Sorbonne Paris Cité, EA 3105, Paris, France
    PLoS ONE 7:e38078. 2012
    ..Kingella kingae, a normal component of the upper respiratory flora, is being increasingly recognized as an important invasive pathogen in young children. Genetic diversity of this species has not been studied...
  11. pmc Chikungunya virus, southeastern France
    Marc Grandadam
    Institut Pasteur, Paris, France
    Emerg Infect Dis 17:910-3. 2011
    ..Sequence analysis of the viral genomes of imported and autochthonous isolates indicated new features for the potential emergence and spread of the virus in Europe...
  12. pmc Using macro-arrays to study routes of infection of Helicobacter pylori in three families
    Josette Raymond
    Service de Bacteriologie, Universite Paris V, Hopital Cochin, Paris, France
    PLoS ONE 3:e2259. 2008
    ..Analysis of the evolutionary dynamics of Helicobacter pylori allowed tracing the spread of infection through populations on different continents but transmission pathways between individual humans have not been clearly described...
  13. doi request reprint A preliminary study of viral metagenomics of French bat species in contact with humans: identification of new mammalian viruses
    Laurent Dacheux
    Institut Pasteur, Lyssavirus Dynamics and Host Adaptation Unit, National Reference Centre for Rabies, WHO Reference Center for Reference and Research on Rabies, Paris, France
    PLoS ONE 9:e87194. 2014
    ..They may therefore constitute a major reservoir of viral diversity that should be analyzed carefully, to determine the role played by bats in the spread of zoonotic viral infections. ..