Ludovic Tailleux

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. ncbi DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells
    Ludovic Tailleux
    INSERM EMI 0013 Institut Universitaire d Hématologie, Assistance Publique Hopitaux de Paris, France
    J Exp Med 197:121-7. 2003
  2. ncbi Constrained intracellular survival of Mycobacterium tuberculosis in human dendritic cells
    Ludovic Tailleux
    , , 1 avenue C. Vellefaux, 75010 Paris, France
    J Immunol 170:1939-48. 2003
  3. ncbi Signature-tagged transposon mutagenesis identifies novel Mycobacterium tuberculosis genes involved in the parasitism of human macrophages
    Vania Rosas Magallanes
    Unit of Mycobacterial Genetics, Institut Pasteur, Paris, France
    Infect Immun 75:504-7. 2007
  4. ncbi Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages
    Ludovic Tailleux
    Institut Pasteur, Unit of Mycobacterial Genetics, Paris, France
    PLoS ONE 3:e1403. 2008
  5. ncbi Is adipose tissue a place for Mycobacterium tuberculosis persistence?
    Olivier Neyrolles
    Genetics and Biochemistry of Microorganisms, Centre National de la Recherche Scientifique, Paris, France
    PLoS ONE 1:e43. 2006
  6. ncbi DC-SIGN induction in alveolar macrophages defines privileged target host cells for mycobacteria in patients with tuberculosis
    Ludovic Tailleux
    Institut Pasteur, Unite de Genetique Mycobacterienne, Paris, France
    PLoS Med 2:e381. 2005
  7. ncbi Promoter variation in the DC-SIGN-encoding gene CD209 is associated with tuberculosis
    Luis B Barreiro
    CNRS FRE2849, Unit of Molecular Prevention and Therapy of Human Diseases, Institut Pasteur, Paris, France
    PLoS Med 3:e20. 2006
  8. ncbi Population variation in NAIP functional copy number confers increased cell death upon Legionella pneumophila infection
    Michele Boniotto
    Unit of Human Evolutionary Genetics, Institut Pasteur, F 75015 Paris, France
    Hum Immunol 73:196-200. 2012
  9. ncbi How is the phagocyte lectin keyboard played? Master class lesson by Mycobacterium tuberculosis
    Ludovic Tailleux
    Institut Pasteur, Unite de Genetique Mycobacterienne, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Trends Microbiol 11:259-63. 2003
  10. ncbi Activation of type III interferon genes by pathogenic bacteria in infected epithelial cells and mouse placenta
    Helene Bierne
    Institut Pasteur, Unité des Interactions Bactéries Cellules, Paris, France
    PLoS ONE 7:e39080. 2012

Detail Information

Publications11

  1. ncbi DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells
    Ludovic Tailleux
    INSERM EMI 0013 Institut Universitaire d Hématologie, Assistance Publique Hopitaux de Paris, France
    J Exp Med 197:121-7. 2003
    ..Thus, as for human immunodeficiency virus (HIV), which is captured by the same receptor, DC-SIGN-mediated entry of M. tuberculosis in DCs in vivo is likely to influence bacterial persistence and host immunity...
  2. ncbi Constrained intracellular survival of Mycobacterium tuberculosis in human dendritic cells
    Ludovic Tailleux
    , , 1 avenue C. Vellefaux, 75010 Paris, France
    J Immunol 170:1939-48. 2003
    ..DCs have evolved unique subcellular trafficking mechanisms to achieve their Ag-presenting functions when infected by intracellular mycobacteria...
  3. ncbi Signature-tagged transposon mutagenesis identifies novel Mycobacterium tuberculosis genes involved in the parasitism of human macrophages
    Vania Rosas Magallanes
    Unit of Mycobacterial Genetics, Institut Pasteur, Paris, France
    Infect Immun 75:504-7. 2007
    ..Mutants disrupted in the ABC transporter-encoding genes Rv0986 and Rv0987 were further characterized as being impaired in their ability to bind to host cells...
  4. ncbi Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages
    Ludovic Tailleux
    Institut Pasteur, Unit of Mycobacterial Genetics, Paris, France
    PLoS ONE 3:e1403. 2008
    ..Here, for the first time, we have been able to investigate gene expression changes in both Mycobacterium tuberculosis, a major human pathogen, and its human host cells, macrophages and dendritic cells...
  5. ncbi Is adipose tissue a place for Mycobacterium tuberculosis persistence?
    Olivier Neyrolles
    Genetics and Biochemistry of Microorganisms, Centre National de la Recherche Scientifique, Paris, France
    PLoS ONE 1:e43. 2006
    ..Long-term mycobacterial persistence in the lungs has been reported, but this may not sufficiently account for strictly extra-pulmonary TB, which represents 10-15% of the reactivation cases...
  6. ncbi DC-SIGN induction in alveolar macrophages defines privileged target host cells for mycobacteria in patients with tuberculosis
    Ludovic Tailleux
    Institut Pasteur, Unite de Genetique Mycobacterienne, Paris, France
    PLoS Med 2:e381. 2005
    ....
  7. ncbi Promoter variation in the DC-SIGN-encoding gene CD209 is associated with tuberculosis
    Luis B Barreiro
    CNRS FRE2849, Unit of Molecular Prevention and Therapy of Human Diseases, Institut Pasteur, Paris, France
    PLoS Med 3:e20. 2006
    ..We reasoned that if DC-SIGN interacts with M. tuberculosis, as well as with other pathogens, variation in this gene might have a broad range of influence in the pathogenesis of a number of infectious diseases, including tuberculosis...
  8. ncbi Population variation in NAIP functional copy number confers increased cell death upon Legionella pneumophila infection
    Michele Boniotto
    Unit of Human Evolutionary Genetics, Institut Pasteur, F 75015 Paris, France
    Hum Immunol 73:196-200. 2012
    ..We postulate that the NAIPFull gene duplication might have been evolutionary maintained, or even selected for, because it may confer an advantage to the host against flagellated bacteria...
  9. ncbi How is the phagocyte lectin keyboard played? Master class lesson by Mycobacterium tuberculosis
    Ludovic Tailleux
    Institut Pasteur, Unite de Genetique Mycobacterienne, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Trends Microbiol 11:259-63. 2003
    ..A set of recent reports has shed light on exploitation of phagocyte surface lectins by the tubercle bacillus. These findings could lead the way to innovative therapeutic approaches...
  10. ncbi Activation of type III interferon genes by pathogenic bacteria in infected epithelial cells and mouse placenta
    Helene Bierne
    Institut Pasteur, Unité des Interactions Bactéries Cellules, Paris, France
    PLoS ONE 7:e39080. 2012
    ..In addition, the feto-placental tissue was responsive to IFN-λ2. Together, these results suggest that IFN-λ may be an important modulator of the immune response to Gram-positive intracellular bacteria in epithelial tissues...
  11. ncbi [DC-SIGN, a key receptor of Mycobacterium tuberculosis?]
    Ludovic Tailleux
    Med Sci (Paris) 19:658-60. 2003