Isabelle Schwartz-Cornil

Summary

Affiliation: Institut National de la Recherche Agronomique
Country: France

Publications

  1. ncbi request reprint Bovine leukaemia virus-induced lymphocytosis in sheep is associated with reduction of spontaneous B cell apoptosis
    I Schwartz-Cornil
    URA INRA d Immuno Pathologie Cellulaire et Moléculaire, Maisons Alfort, France
    J Gen Virol 78:153-62. 1997
  2. pmc Heterologous protection induced by the inner capsid proteins of rotavirus requires transcytosis of mucosal immunoglobulins
    Isabelle Schwartz-Cornil
    U892 INRA, Domaine de Vilvert, 78352 Jouy en Josas, France
    J Virol 76:8110-7. 2002
  3. doi request reprint Steady state pig dendritic cells migrating in skin draining pseudo-afferent lymph are semi-mature
    Nicolas Bertho
    Virologie et Immunologie Moléculaires UR892, Institut National de Recherche Agronomique, Domaine de Vilvert, Jouy en Josas, France
    Vet Immunol Immunopathol 144:430-6. 2011
  4. pmc Characterization of dendritic cells subpopulations in skin and afferent lymph in the swine model
    Florian Marquet
    Virologie et Immunologie Moléculaires UR892, Institut National de la Recherche Agronomique, Domaine de Vilvert, Jouy en Josas, France
    PLoS ONE 6:e16320. 2011
  5. pmc NS3 of bluetongue virus interferes with the induction of type I interferon
    Emilie Chauveau
    Maisons Alfort Laboratory for Animal Health, Anses, INRA, ENVA, UMR 1161 Virology, Maisons Alfort, France
    J Virol 87:8241-6. 2013
  6. doi request reprint Bluetongue virus: virology, pathogenesis and immunity
    Isabelle Schwartz-Cornil
    Virologie et Immunologie Moléculaires, UR892 INRA, Domaine de Vilvert, 78352 Jouy en Josas Cedex, France
    Vet Res 39:46. 2008
  7. ncbi request reprint Probing leukocyte traffic in lymph from oro-nasal mucosae by cervical catheterization in a sheep model
    Isabelle Schwartz-Cornil
    Virologie et Immunologie Moléculaires UR892 INRA, Domaine de Vilvert, 78352 Jouy en Josas Cedex, France
    J Immunol Methods 305:152-61. 2005
  8. ncbi request reprint Plasmacytoid dendritic cells migrate in afferent skin lymph
    Florentina Pascale
    Virologie et Immunologie Moléculaires, UR892 Institut National de la Recherche Agronomique, Domaine de Vilvert, Jouy en Josas, France
    J Immunol 180:5963-72. 2008
  9. doi request reprint Existence of CD8α-like dendritic cells with a conserved functional specialization and a common molecular signature in distant mammalian species
    Vanessa Contreras
    Virologie et Immunologie Moléculaires UR892, Institut National de Recherche Agronomique, Domaine de Vilvert, Jouy en Josas, France
    J Immunol 185:3313-25. 2010
  10. ncbi request reprint Cervical duct cannulation in sheep for collection of afferent lymph dendritic cells from head tissues
    Isabelle Schwartz-Cornil
    Virologie et Immunologie Moléculaires UR892 INRA, Domaine de Vilvert, 78352 Jouy en Josas Cedex, France
    Nat Protoc 1:874-9. 2006

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Bovine leukaemia virus-induced lymphocytosis in sheep is associated with reduction of spontaneous B cell apoptosis
    I Schwartz-Cornil
    URA INRA d Immuno Pathologie Cellulaire et Moléculaire, Maisons Alfort, France
    J Gen Virol 78:153-62. 1997
    ..Altogether, these data suggest that both BLV-induced B cell proliferation and extended survival are involved in the lymphocytotic stage encountered in BLV infection in sheep...
  2. pmc Heterologous protection induced by the inner capsid proteins of rotavirus requires transcytosis of mucosal immunoglobulins
    Isabelle Schwartz-Cornil
    U892 INRA, Domaine de Vilvert, 78352 Jouy en Josas, France
    J Virol 76:8110-7. 2002
    ..These results indicate that J-chain-mediated transcytosis of Ig participates in the clearance of RV and that epithelial pIgR-mediated transport of Ig is involved in the heterologous protection induced by VLP2/6...
  3. doi request reprint Steady state pig dendritic cells migrating in skin draining pseudo-afferent lymph are semi-mature
    Nicolas Bertho
    Virologie et Immunologie Moléculaires UR892, Institut National de Recherche Agronomique, Domaine de Vilvert, Jouy en Josas, France
    Vet Immunol Immunopathol 144:430-6. 2011
    ..Thus, using the pig skin model which is relevant to human, we show that skin-derived DC constantly migrate at an intermediate state of maturation that can be further enhanced upon appropriate stimulation...
  4. pmc Characterization of dendritic cells subpopulations in skin and afferent lymph in the swine model
    Florian Marquet
    Virologie et Immunologie Moléculaires UR892, Institut National de la Recherche Agronomique, Domaine de Vilvert, Jouy en Josas, France
    PLoS ONE 6:e16320. 2011
    ..This work, by showing similarities between human, mouse and swine skin DC, establishes pig as a model of choice for the development of transcutaneous immunisation strategies targeting DC...
  5. pmc NS3 of bluetongue virus interferes with the induction of type I interferon
    Emilie Chauveau
    Maisons Alfort Laboratory for Animal Health, Anses, INRA, ENVA, UMR 1161 Virology, Maisons Alfort, France
    J Virol 87:8241-6. 2013
    ..In this study, we assessed the ability of BTV to interfere with IFN-I synthesis and identified the nonstructural viral protein NS3 as an antagonist of the IFN-I system. ..
  6. doi request reprint Bluetongue virus: virology, pathogenesis and immunity
    Isabelle Schwartz-Cornil
    Virologie et Immunologie Moléculaires, UR892 INRA, Domaine de Vilvert, 78352 Jouy en Josas Cedex, France
    Vet Res 39:46. 2008
    ..New recombinant vaccine strategies that allow differentiating infected from vaccinated animals and that generate cross protective immunity are urgently needed to efficiently combat this worldwide threatening disease...
  7. ncbi request reprint Probing leukocyte traffic in lymph from oro-nasal mucosae by cervical catheterization in a sheep model
    Isabelle Schwartz-Cornil
    Virologie et Immunologie Moléculaires UR892 INRA, Domaine de Vilvert, 78352 Jouy en Josas Cedex, France
    J Immunol Methods 305:152-61. 2005
    ....
  8. ncbi request reprint Plasmacytoid dendritic cells migrate in afferent skin lymph
    Florentina Pascale
    Virologie et Immunologie Moléculaires, UR892 Institut National de la Recherche Agronomique, Domaine de Vilvert, Jouy en Josas, France
    J Immunol 180:5963-72. 2008
    ..Thus, pDC can link innate and acquired immunity by migrating from tissue to draining node via lymph, similarly to conventional dendritic cells...
  9. doi request reprint Existence of CD8α-like dendritic cells with a conserved functional specialization and a common molecular signature in distant mammalian species
    Vanessa Contreras
    Virologie et Immunologie Moléculaires UR892, Institut National de Recherche Agronomique, Domaine de Vilvert, Jouy en Josas, France
    J Immunol 185:3313-25. 2010
    ..Our results unravel a unifying definition of the CD8alpha(+)-like DCs across mammalian species and identify molecular candidates that could be used for the design of vaccines applying to mammals in general...
  10. ncbi request reprint Cervical duct cannulation in sheep for collection of afferent lymph dendritic cells from head tissues
    Isabelle Schwartz-Cornil
    Virologie et Immunologie Moléculaires UR892 INRA, Domaine de Vilvert, 78352 Jouy en Josas Cedex, France
    Nat Protoc 1:874-9. 2006
    ..This protocol is directed to experienced postdoctoral researchers...
  11. pmc Sensing and control of bluetongue virus infection in epithelial cells via RIG-I and MDA5 helicases
    Emilie Chauveau
    Anses, Maisons Alfort Laboratory for Animal Health, Anses, INRA, ENVA, UMR 1161 Virology, Maisons Alfort, France
    J Virol 86:11789-99. 2012
    ..Moreover, we also showed that overexpression of either RIG-I or MDA5 impaired BTV expression in infected A549 cells. Overall, this indicates that RIG-I and MDA5 can both contribute to the recognition and control of BTV infection...
  12. doi request reprint Modified model of VX2 tumor overexpressing vascular endothelial growth factor
    Florentina Pascale
    ArchimMed Paris, France
    J Vasc Interv Radiol 23:809-817.e2. 2012
    ..To determine whether upregulated expression of vascular endothelial growth factor (VEGF) in VX2 cells can increase vessel density (VD) and reduce tumor necrosis...
  13. ncbi request reprint Production of two vaccinating recombinant rotavirus proteins in the milk of transgenic rabbits
    Eric Soler
    Biologie du Développement et de la Reproduction, INRA, Bat 440, Jouy en Josas, France
    Transgenic Res 14:833-44. 2005
    ..To our knowledge, this is the first report of transgenic mammal bioreactors allowing the rapid co-production of two recombinant viral proteins in milk to be used as a vaccine...
  14. pmc Dendritic Cell Subtypes from Lymph Nodes and Blood Show Contrasted Gene Expression Programs upon Bluetongue Virus Infection
    Suzana Ruscanu
    Virologie et Immunologie Moléculaires, UR892 INRA, Domaine de Vilvert, Jouy en Josas, France
    J Virol 87:9333-43. 2013
    ..These findings open the avenue to target DCs for therapeutic interventions in viral hemorrhagic diseases. ..
  15. doi request reprint Canine adenoviruses elicit both humoral and cell-mediated immune responses against rabies following immunisation of sheep
    Coraline Bouet-Cararo
    UMR 1161 Virologie, ANSES INRA ENVA, Maisons Alfort, France
    Vaccine 29:1304-10. 2011
    ..These results suggest that vectors derived from canine adenovirus 2 could be considered for the development of promising vaccines in the ruminant species...
  16. ncbi request reprint Impact of large mammals models in immunology
    Isabelle Schwartz-Cornil
    Virologie et Immunologie Moléculaires, UR892 INRA, Domaine de Vilvert, 78352 Jouy en Josas Cedex, France
    Reprod Fertil Dev 24:287-8. 2011
    ..New knowledge and treatments generated from iPS cells can next be translated and applied in HD monkeys from whom the stem cells were derived, thus the goal of personalized medicine can also be evaluated...
  17. ncbi request reprint Recombinant rotavirus inner core proteins produced in the milk of transgenic rabbits confer a high level of protection after intrarectal delivery
    Eric Soler
    Biologie du Développement et de la Reproduction, Domaine de Vilvert, 78352 Jouy en Josas Cedex, France
    Vaccine 25:6373-80. 2007
    ..We thus demonstrate in clinically feasible settings that mass production of viral protein in transgenic milk is a promising way to generate subunit vaccine against rotavirus...
  18. pmc Bluetongue virus targets conventional dendritic cells in skin lymph
    Behzad Hemati
    Virologie et Immunologie Moléculaires, UR892 INRA, Domaine de Vilvert, 78352 Jouy en Josas Cedex, France
    J Virol 83:8789-99. 2009
    ..BTV initially targets cDCs while preserving their functional properties, reflecting the optimal adaptation of the virus to its host cells for its first spread...
  19. ncbi request reprint Enrichment for a CD26hi SIRP- subset in lymph dendritic cells from the upper aero-digestive tract
    Mathieu Epardaud
    VIM UR892 INRA, Cedex, France
    J Leukoc Biol 76:553-61. 2004
    ..This modulation of DC traffic to lymph nodes by mucosal surfaces is likely to affect the bias of the mucosal immune responses...
  20. pmc The VP6 protein of rotavirus interacts with a large fraction of human naive B cells via surface immunoglobulins
    Nathalie Parez
    Service des Urgences Médicales Pédiatriques, Hopital Armand Trousseau, 26 Ave du Dr Arnold Netter, 75571 Paris Cedex 12, France
    J Virol 78:12489-96. 2004
    ..We propose that naive B cell-VP6 interaction might influence the strength and quality of the acquired immune response and should be considered for elaborating RV vaccine strategies...
  21. ncbi request reprint Migratory monocytes and granulocytes are major lymphatic carriers of Salmonella from tissue to draining lymph node
    Michel Bonneau
    Domaine de Vilvert, 78352 Jouy en Josas Cedex, France
    J Leukoc Biol 79:268-76. 2006
    ..The data suggest that immunity to bacteria may result from the complex interplay between a mixture of phagocytic cell types, which transport antigens and are massively recruited via lymph to decisional lymph nodes...
  22. pmc Rectal immunization with rotavirus virus-like particles induces systemic and mucosal humoral immune responses and protects mice against rotavirus infection
    Nathalie Parez
    Service des Urgences Médicales Pédiatriques, Hopital Armand Trousseau, 26 Ave du Dr Arnold Netter, 75571 Paris Cedex 12, France
    J Virol 80:1752-61. 2006
    ..Rectal delivery of a VLP-based vaccine might allow the use of adjuvants less toxic than, but as efficient as, CT...
  23. pmc Rotavirus anti-VP6 secretory immunoglobulin A contributes to protection via intracellular neutralization but not via immune exclusion
    Blaise Corthesy
    R and D Laboratory of the Division of Immunology and Allergy, DMI CHUV, Rue du Bugnon, 1011 Lausanne, Switzerland
    J Virol 80:10692-9. 2006
    ..These findings identify a mechanism whereby the well-conserved immunodominant VP6 protein can function as a target for heterotypic antibodies and protective immunity...
  24. pmc Peripheral blood B-cell death compensates for excessive proliferation in lymphoid tissues and maintains homeostasis in bovine leukemia virus-infected sheep
    Christophe Debacq
    Molecular and Cellular Biology, FNRS FUSAG, Gembloux, Belgium
    J Virol 80:9710-9. 2006
    ..Lymphocyte homeostasis is thus maintained by biphasic kinetics in two distinct tissues, emphasizing a very dynamic process during BLV infection...
  25. pmc Spleen-dependent turnover of CD11b peripheral blood B lymphocytes in bovine leukemia virus-infected sheep
    Arnaud Florins
    National Fund for Scientific Research, Molecular and Cellular Biology Laboratory, 13 avenue Maréchal Juin, 5030 Gembloux, Belgium
    J Virol 80:11998-2008. 2006
    ..We show that the enhanced cell death observed in BLV-infected sheep is abrogated after splenectomy, revealing a key role of the spleen in B-lymphocyte dynamics...
  26. ncbi request reprint Cell dynamics and immune response to BLV infection: a unifying model
    Arnaud Florins
    Molecular and Cellular Biology, FNRS FUSAG, Gembloux, Belgium
    Front Biosci 12:1520-31. 2007
    ..As conclusion, we propose a hypothetical model unifying all these mechanisms...