Martin Schlumberger

Summary

Affiliation: Institut Gustave Roussy
Country: France

Publications

  1. doi request reprint [Nuclear-power-plant accidents: thyroid cancer incidence and radiation-related health effects from the Chernobyl accident]
    Martin Schlumberger
    Universite Paris Sud, service de médecine nucléaire et cancérologie endocrinienne, Institut Gustave Roussy, 94805 Villejuif Cedex, France
    Med Sci (Paris) 28:746-56. 2012
  2. doi request reprint [Thyroid cancer following exposure to ionising radiation]
    M Schlumberger
    Institut de Cancerologie Gustave Roussy, 114 rue Edouard Vaillant, Villejuif Cedex, France
    Cancer Radiother 15:394-9. 2011
  3. doi request reprint Treatment and follow-up of low-risk patients with thyroid cancer
    Martin Schlumberger
    Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy and University Paris Sud, 39 rue Camille Desmoulins, 94805 Villejuif, France
    Nat Rev Endocrinol 7:625-8. 2011
  4. doi request reprint Phase II study of safety and efficacy of motesanib in patients with progressive or symptomatic, advanced or metastatic medullary thyroid cancer
    Martin J Schlumberger
    Institut Gustave Roussy, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    J Clin Oncol 27:3794-801. 2009
  5. pmc Rationale and design of decision: a double-blind, randomized, placebo-controlled phase III trial evaluating the efficacy and safety of sorafenib in patients with locally advanced or metastatic radioactive iodine (RAI)-refractory, differentiated thyroid ca
    Marcia S Brose
    Department of Otorhinolaryngology Head and Neck Surgery, The University of Pennsylvania, Abramson Cancer Center, Clinical Research Building, Room 127, 425 Curie Boulevard, Philadelphia, PA 19104, USA
    BMC Cancer 11:349. 2011
  6. ncbi request reprint Imaging medullary thyroid carcinoma with persistent elevated calcitonin levels
    Anne Laure Giraudet
    Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy, 94805 Villejuif Cedex, France
    J Clin Endocrinol Metab 92:4185-90. 2007
  7. doi request reprint Charcoal suspension tattoo localization for differentiated thyroid cancer recurrence
    Dana M Hartl
    Department of Otolaryngology Head and Neck Surgery, Institut Gustave Roussy, Villejuif, France
    Ann Surg Oncol 16:2602-8. 2009
  8. ncbi request reprint Neck recurrence from thyroid carcinoma: serum thyroglobulin and high-dose total body scan are not reliable criteria for cure after radioiodine treatment
    Anne Bachelot
    Department of Nuclear Medicine and Endocrine Tumours, Institut Gustave Roussy, Villejuif Cedex, France
    Clin Endocrinol (Oxf) 62:376-9. 2005
  9. pmc Follicular thyroid tumors with the PAX8-PPARgamma1 rearrangement display characteristic genetic alterations
    Ludovic Lacroix
    Functional Genomic Unit, Institut Gustave Roussy, Villejuif Cedex, France
    Am J Pathol 167:223-31. 2005
  10. ncbi request reprint Functional characterization of human thyroid tissue with immunohistochemistry
    Antongiulio Faggiano
    Department of Pathology, Commissariat à l Energie Atomique LRC29V, Institut Gustave Roussy, University Paris Sud, Villejuif Cedex, France
    Thyroid 17:203-11. 2007

Detail Information

Publications75

  1. doi request reprint [Nuclear-power-plant accidents: thyroid cancer incidence and radiation-related health effects from the Chernobyl accident]
    Martin Schlumberger
    Universite Paris Sud, service de médecine nucléaire et cancérologie endocrinienne, Institut Gustave Roussy, 94805 Villejuif Cedex, France
    Med Sci (Paris) 28:746-56. 2012
    ....
  2. doi request reprint [Thyroid cancer following exposure to ionising radiation]
    M Schlumberger
    Institut de Cancerologie Gustave Roussy, 114 rue Edouard Vaillant, Villejuif Cedex, France
    Cancer Radiother 15:394-9. 2011
    ..In case of contamination with radioiodines, administration of potassium iodide can prevent thyroid irradiation...
  3. doi request reprint Treatment and follow-up of low-risk patients with thyroid cancer
    Martin Schlumberger
    Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy and University Paris Sud, 39 rue Camille Desmoulins, 94805 Villejuif, France
    Nat Rev Endocrinol 7:625-8. 2011
    ..These modifications of current protocols will improve the quality of life of patients, potentially decrease morbidity and considerably reduce the cost of treatment and follow-up...
  4. doi request reprint Phase II study of safety and efficacy of motesanib in patients with progressive or symptomatic, advanced or metastatic medullary thyroid cancer
    Martin J Schlumberger
    Institut Gustave Roussy, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    J Clin Oncol 27:3794-801. 2009
    ....
  5. pmc Rationale and design of decision: a double-blind, randomized, placebo-controlled phase III trial evaluating the efficacy and safety of sorafenib in patients with locally advanced or metastatic radioactive iodine (RAI)-refractory, differentiated thyroid ca
    Marcia S Brose
    Department of Otorhinolaryngology Head and Neck Surgery, The University of Pennsylvania, Abramson Cancer Center, Clinical Research Building, Room 127, 425 Curie Boulevard, Philadelphia, PA 19104, USA
    BMC Cancer 11:349. 2011
    ..The DECISION trial was designed to assess the ability of sorafenib to improve PFS in patients with locally advanced or metastatic, radioactive iodine (RAI)-refractory DTC...
  6. ncbi request reprint Imaging medullary thyroid carcinoma with persistent elevated calcitonin levels
    Anne Laure Giraudet
    Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy, 94805 Villejuif Cedex, France
    J Clin Endocrinol Metab 92:4185-90. 2007
    ..Because calcitonin level remains elevated after initial treatment in many medullary thyroid carcinoma (MTC) patients without evidence of disease in the usual imaging work-up, there is a need to define optimal imaging procedures...
  7. doi request reprint Charcoal suspension tattoo localization for differentiated thyroid cancer recurrence
    Dana M Hartl
    Department of Otolaryngology Head and Neck Surgery, Institut Gustave Roussy, Villejuif, France
    Ann Surg Oncol 16:2602-8. 2009
    ..Intraoperative localization of these small foci in previously dissected necks is a surgical challenge. We describe a new technique for ultrasound-guided tattooing to facilitate excision...
  8. ncbi request reprint Neck recurrence from thyroid carcinoma: serum thyroglobulin and high-dose total body scan are not reliable criteria for cure after radioiodine treatment
    Anne Bachelot
    Department of Nuclear Medicine and Endocrine Tumours, Institut Gustave Roussy, Villejuif Cedex, France
    Clin Endocrinol (Oxf) 62:376-9. 2005
    ....
  9. pmc Follicular thyroid tumors with the PAX8-PPARgamma1 rearrangement display characteristic genetic alterations
    Ludovic Lacroix
    Functional Genomic Unit, Institut Gustave Roussy, Villejuif Cedex, France
    Am J Pathol 167:223-31. 2005
    ..These data identify several differentially expressed genes, such as FGD3, that may serve as potential targets of PPARgamma and as members of novel molecular pathways involved in the development of thyroid carcinomas...
  10. ncbi request reprint Functional characterization of human thyroid tissue with immunohistochemistry
    Antongiulio Faggiano
    Department of Pathology, Commissariat à l Energie Atomique LRC29V, Institut Gustave Roussy, University Paris Sud, Villejuif Cedex, France
    Thyroid 17:203-11. 2007
    ....
  11. doi request reprint Optimization of staging of the neck with prophylactic central and lateral neck dissection for papillary thyroid carcinoma
    Dana M Hartl
    Departments of Otolaryngology Head and Neck Surgery, Institut Gustave Roussy and University Paris Sud, Villejuif Cedex, France
    Ann Surg 255:777-83. 2012
    ..To analyze the yield and rate of node metastases (pN1) for prophylactic central (CND) and lateral neck dissection (LND) for papillary thyroid carcinoma, the risk factors for pN1, and outcomes...
  12. doi request reprint Prognostic markers of survival after combined mitotane- and platinum-based chemotherapy in metastatic adrenocortical carcinoma
    Pasqualino Malandrino
    Service de Médecine Nucléaire et de Cancérologie Endocrinienne, Institut Gustave Roussy, Universite Paris XI, 39 rue Camille Desmoulins, Villejuif Cedex, France
    Endocr Relat Cancer 17:797-807. 2010
    ..03 and <0.001). Our study suggests a prognostic role for mitotane therapy and objective response to platinum-based chemotherapy...
  13. ncbi request reprint Prognostic factors for persistent or recurrent disease of papillary thyroid carcinoma with neck lymph node metastases and/or tumor extension beyond the thyroid capsule at initial diagnosis
    Sophie Leboulleux
    Department of Nuclear Medicine and Endocrine Tumors, Institut National de la Santé et de la Recherche Médicale U605, Institut Gustave Roussy, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    J Clin Endocrinol Metab 90:5723-9. 2005
    ..Initial treatment, performed at the Institut Gustave Roussy between 1987 and 1997, included in all patients a total thyroidectomy with central and ipsilateral en bloc neck dissection followed by radioactive iodine ablation...
  14. doi request reprint Prophylactic lymph node dissection for papillary thyroid cancer less than 2 cm: implications for radioiodine treatment
    Stephane Bonnet
    Department of Oncologic Surgery, Institut Gustave Roussy, Villejuif Cedex, France
    J Clin Endocrinol Metab 94:1162-7. 2009
    ..The aim was to determine the effect of lymph node (LN) staging on the indication for treatment with radioiodine...
  15. ncbi request reprint Expression of the apical iodide transporter in human thyroid tissues: a comparison study with other iodide transporters
    Ludovic Lacroix
    Department of Clinical Biology, Commissariat à l Energie Atomique LRC29V, Institut Gustave Roussy, 94805 Villejuif Cedex, France
    J Clin Endocrinol Metab 89:1423-8. 2004
    ..Expression of AIT protein was undetectable in most papillary carcinomas and was weak but detectable in most follicular carcinomas; it was negative in anaplastic carcinomas...
  16. doi request reprint Is (18)F-fluorodeoxyglucose-PET/CT useful for the presurgical characterization of thyroid nodules with indeterminate fine needle aspiration cytology?
    Desiree Deandreis
    Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy, Villejuif, France
    Thyroid 22:165-72. 2012
    ..The goal of this study was to evaluate the role of FDG-PET/computed tomography (CT) in predicting malignancy of thyroid nodules with indeterminate FNAC and to correlate FDG uptake with pathological and ultrasonographic (US) features...
  17. ncbi request reprint Age-dependent variation of follicular size and expression of iodine transporters in human thyroid tissue
    Antongiulio Faggiano
    Department of Nuclear Medicine, Commissariat a l Energie Atomique, Institut Gustave Roussy, 39 rue C Demoulins, 94805 Villejuif Cedex, France
    J Nucl Med 45:232-7. 2004
    ....
  18. ncbi request reprint Correlation between [18f]fluorodeoxyglucose positron-emission tomography scan and histology of pelvic nodes in early-stage cervical cancer
    Enrica Bentivegna
    Department of Surgery, Gustave Roussy Institute University Paris Sud, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Anticancer Res 30:1029-32. 2010
    ....
  19. doi request reprint Role of FDG PET/CT and chest CT in the follow-up of lung lesions treated with radiofrequency ablation
    Desiree Deandreis
    Department of Nuclear Medicine and Endocrine Oncology, Institute Gustave Roussy and University Paris Sud XI, 39 rue Camille Desmoulins, 94805 Villejuif, France
    Radiology 258:270-6. 2011
    ..To compare fluorine 18 fluorodeoxyglucose (FDG) positron emission tomography (PET) combined with computed tomography (PET/CT) and chest CT in the evaluation of the effectiveness of lung radiofrequency (RF) ablation...
  20. doi request reprint Histologic results of para-aortic lymphadenectomy in patients treated for stage IB2/II cervical cancer with negative [18F]fluorodeoxyglucose positron emission tomography scans in the para-aortic area
    Mathias Boughanim
    Department of Surgery, Institut Gustave Roussy, and University Paris Sud, Villejuif, France
    J Clin Oncol 26:2558-61. 2008
    ....
  21. doi request reprint Aggressive inherited and sporadic medullary thyroid carcinomas display similar oncogenic pathways
    Nabahet Ameur
    CNRS FRE 2939, Institut de Cancerologie Gustave Roussy, Villejuif, France
    Endocr Relat Cancer 16:1261-72. 2009
    ..Using a MTC cell line, silencing of RET induced the inhibition of PTN gene expression. Overall, our results suggest that familial MTC and sporadic MTC could activate similar oncogenic pathways...
  22. doi request reprint Liver/biliary injuries following chemoembolisation of endocrine tumours and hepatocellular carcinoma: lipiodol vs. drug-eluting beads
    Boris Guiu
    Department of Interventional Radiology, Institut Gustave Roussy, Villejuif, France
    J Hepatol 56:609-17. 2012
    ..This study describes and compares liver/biliary injuries encountered with TACE in tumours developed in cirrhotic (hepatocellular carcinoma (HCC)) and non-cirrhotic (endocrine tumours (NETs)) livers...
  23. doi request reprint High rate of multifocality and occult lymph node metastases in papillary thyroid carcinoma arising in thyroglossal duct cysts
    Dana M Hartl
    Department of Otolaryngology Head and Neck Surgery, Institut Gustave Roussy, Villejuif, France
    Ann Surg Oncol 16:2595-601. 2009
    ..The incidence of cancer in thyroglossal duct cysts (TDC) is low and management is controversial. The objective was to report the rate of multifocality, lymph node metastases, and long-term results for TDC carcinomas in adults...
  24. ncbi request reprint Ultrasound criteria of malignancy for cervical lymph nodes in patients followed up for differentiated thyroid cancer
    Sophie Leboulleux
    Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    J Clin Endocrinol Metab 92:3590-4. 2007
    ..Neck ultrasonography (US) has become a keystone in the follow-up of patients with differentiated thyroid cancer...
  25. doi request reprint Progression of medullary thyroid carcinoma: assessment with calcitonin and carcinoembryonic antigen doubling times
    Anne Laure Giraudet
    Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy and University Paris Sud, 94805 Villejuif Cedex, France
    Eur J Endocrinol 158:239-46. 2008
    ..The progression of medullary thyroid cancer is difficult to assess with imaging modalities; we studied the interest of calcitonin and carcinoembryonic antigen (CEA) doubling times and of Ki-67 labeling and mitotic index (MI)...
  26. ncbi request reprint [Oncogenes and thyroid tumors]
    Ludovic Lacroix
    Institut Gustave Roussy, 94805 Villejuif Cedex
    Bull Cancer 92:37-43. 2005
    ..Follicular carcinomas are characterized by the presence of a RAS mutation or of a PAX8-PPARgamma rearrangement. Inactivating mutations of the p53 gene are found only in anaplastic thyroid carcinomas...
  27. ncbi request reprint Rationale for central and bilateral lymph node dissection in sporadic and hereditary medullary thyroid cancer
    Claudia Scollo
    Nuclear Medicine, Institut Gustave Roussy, 94805 Villejuif Cedex, France
    J Clin Endocrinol Metab 88:2070-5. 2003
    ....
  28. doi request reprint Body composition variation and impact of low skeletal muscle mass in patients with advanced medullary thyroid carcinoma treated with vandetanib: results from a placebo-controlled study
    Marie Hélène Massicotte
    Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy, F 94805 Villejuif, France
    J Clin Endocrinol Metab 98:2401-8. 2013
    ....
  29. doi request reprint Frequency and characterization of gastro-entero-pancreatic neuroendocrine tumor patients with high-grade of uptake at somatostatin receptor scintigraphy
    Cecile N Chougnet
    Departments of Nuclear Medicine and Endocrine Tumors, Institut Gustave Roussy, University Paris Sud, 114 rue Edouard Vaillant, 94805 Villejuif Cedex, France
    Endocr Relat Cancer 20:229-39. 2013
    ..Functioning G1 NEN patients could be the best candidates for PRRT. Randomized trials are expected to confirm this result...
  30. doi request reprint Postradioiodine treatment whole-body scan in the era of 18-fluorodeoxyglucose positron emission tomography for differentiated thyroid carcinoma with elevated serum thyroglobulin levels
    Sophie Leboulleux
    Department of Nuclear Medicine and Endocrine Oncology, Institute Gustave Roussy, University of Paris Sud, Villejuif, France
    Thyroid 22:832-8. 2012
    ....
  31. doi request reprint Strategies of radioiodine ablation in patients with low-risk thyroid cancer
    Martin Schlumberger
    Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy and University Paris Sud, Villejuif, France
    N Engl J Med 366:1663-73. 2012
    ..The administration of the smallest possible amount of radioiodine would improve care...
  32. doi request reprint Transarterial chemoembolization of liver metastases from well differentiated gastroenteropancreatic endocrine tumors with doxorubicin-eluting beads: preliminary results
    Thierry de Baere
    Department of Interventional Radiology, Institut Gustave Roussy, rue Camille Desmoulins, Villejuif 94805, France
    J Vasc Interv Radiol 19:855-61. 2008
    ..To evaluate the feasibility, safety, and efficacy of transarterial chemoembolization (TACE) of progressive liver metastases from well differentiated gastroenteropancreatic endocrine (GEP) tumors with drug-eluting beads (DEBs)...
  33. doi request reprint Prognostic factors influencing survival from metastatic (stage IV) gastroenteropancreatic well-differentiated endocrine carcinoma
    Cosimo Durante
    Service de Médecine Nucléaire et de Cancérologie Endocrinienne, Institut Gustave Roussy, Universite Paris XI, 94805 Villejuif Cedex, France
    Endocr Relat Cancer 16:585-97. 2009
    ..This study enables the stratification of metastatic GEP WDEC patients into distinct risk groups. These risk categories can be used to tailor therapeutic approaches and also to design and interpret clinical trials...
  34. doi request reprint Clinical trials for progressive differentiated thyroid cancer: patient selection, study design, and recent advances
    Martin Schlumberger
    Department of Nuclear Medicine and Endocrine Oncology, Referral Center for Refractory Thyroid Tumors, Institut National du Cancer, Institut Gustave Roussy, Villejuif, France
    Thyroid 19:1393-400. 2009
    ..In those with progressive disease, treatment with kinase inhibitors should be offered preferably in the context of a prospective trial...
  35. ncbi request reprint Medullary thyroid carcinoma
    Sophie Leboulleux
    Institut Gustave Roussy, Villejuif, France
    Clin Endocrinol (Oxf) 61:299-310. 2004
    ..However, there is no effective treatment for distant metastases, and new therapeutic modalities are urgently needed...
  36. ncbi request reprint PAX8 and peroxisome proliferator-activated receptor gamma 1 gene expression status in benign and malignant thyroid tissues
    Ludovic Lacroix
    CNRS UMR 8125 Commissariat a l Energie Atomique, LRC29V, and Department of Clinical Biology, Institut Gustave Roussy, 94805 Villejuif Cedex, France
    Eur J Endocrinol 151:367-74. 2004
    ....
  37. pmc Kinase inhibitors for advanced medullary thyroid carcinoma
    Martin Schlumberger
    Centre de Référence Tumeurs Réfractaires de la Thyroïde, Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy, University Paris Sud XI, Villejuif, France
    Clinics (Sao Paulo) 67:125-9. 2012
    ..In patients with progressive disease, treatment with kinase inhibitors should be offered...
  38. doi request reprint High-dose mitotane strategy in adrenocortical carcinoma: prospective analysis of plasma mitotane measurement during the first 3 months of follow-up
    Sophie Mauclère-Denost
    Department of Nuclear Medicine and Endocrine Tumors, Institut Gustave Roussy, Univ Paris Sud, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Eur J Endocrinol 166:261-8. 2012
    ..The benefit-to-risk ratio of a high-dose strategy at the initiation of mitotane treatment of adrenocortical carcinoma (ACC) remains unknown...
  39. ncbi request reprint Follow-up of low-risk patients with differentiated thyroid carcinoma: a European perspective
    Martin Schlumberger
    Institut Gustave Roussy, Villejuif, France
    Eur J Endocrinol 150:105-12. 2004
    ..We sought to develop an improved protocol for the follow-up of low-risk patients with DTC based on the findings of recent studies...
  40. ncbi request reprint Follow-up and management of differentiated thyroid carcinoma: a European perspective in clinical practice
    Martin Schlumberger
    service de Medicine Nucleaire, Institut Gustave Roussy, 94805 Villejuif, France
    Eur J Endocrinol 151:539-48. 2004
    ..We also offer expanded and additional comments on various issues in the management of DTC...
  41. doi request reprint 18F-fluorodeoxyglucose positron emission tomography and computed tomography in anaplastic thyroid cancer
    Thomas Poisson
    Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy and University Paris Sud XI, 94805, Villejuif Cedex, France
    Eur J Nucl Med Mol Imaging 37:2277-85. 2010
    ....
  42. ncbi request reprint Relationship between tumor burden and serum thyroglobulin level in patients with papillary and follicular thyroid carcinoma
    Anne Bachelot
    Institut Gustave Roussy, Villejuif, France
    Thyroid 12:707-11. 2002
    ..Nevertheless, undetectable serum Tg should not be considered as a reliable criteria to exclude a minimal tumor burden in patients who have already been treated with (131)I...
  43. ncbi request reprint Combined treatment of anaplastic thyroid carcinoma with surgery, chemotherapy, and hyperfractionated accelerated external radiotherapy
    Renaud de Crevoisier
    Department of Radiation Oncology, Institut Gustave Roussy, Villejuif, France
    Int J Radiat Oncol Biol Phys 60:1137-43. 2004
    ..To analyze a prospective protocol combining surgery, chemotherapy (CT), and hyperfractionated accelerated radiotherapy (RT) in anaplastic thyroid carcinoma...
  44. doi request reprint [Differentiated thyroid cancer in childhood]
    Sophie Leboulleux
    Institut Gustave Roussy, Universite Paris Sud, Service de Médecine Nucléaire et de Cancérologie Endocrinienne, Villejuif, France
    Bull Cancer 99:1093-9. 2012
    ..Life-long thyroxine treatment is given to all patients. Long term prognosis is favourable, but thyroid cancer related deaths have been reported some decades after initial treatment...
  45. doi request reprint 131I effective half-life and dosimetry in thyroid cancer patients
    Hervé Remy
    Department of Nuclear Medicine, Institut Gustave Roussy, Villejuif, France
    J Nucl Med 49:1445-50. 2008
    ..There are still some uncertainties concerning parameters that may influence the effective half-life of (131)I and the absorbed doses by extrathyroidal organs...
  46. ncbi request reprint Liver resection (and associated extrahepatic resections) for metastatic well-differentiated endocrine tumors: a 15-year single center prospective study
    Dominique Elias
    Department of Surgical Oncology, Comprehensive Cancer Center, Institut Gustave Roussy, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Surgery 133:375-82. 2003
    ..However, surveillance alone yields only a 22% 5-year survival when metastases occur. The aim of this study was to determine the results of hepatic and extra hepatic resections and to clarify the indications of surgery...
  47. ncbi request reprint Differential expression of galectin-3 in medullary thyroid carcinoma and C-cell hyperplasia
    Antongiulio Faggiano
    Department of Pathology, Commissariat à l Energie Atomique LRC29V, Institut Gustave Roussy, F 94805 Villejuif Cedex, France
    Clin Endocrinol (Oxf) 57:813-9. 2002
    ..The reliability of this marker in the differential diagnosis between medullary thyroid carcinoma and C-cell hyperplasia was studied by immunohistochemistry...
  48. doi request reprint Thoracic 131I uptake after previous pneumonectomy in patients treated for differentiated thyroid cancer
    Camila Nascimento
    Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy, Villejuif, France
    Clin Nucl Med 37:587-90. 2012
    ..We describe 3 cases of unilateral thoracic 131I uptake in patients previously treated by pneumonectomy for lung cancer, without evidence of persistent lung cancer...
  49. pmc Tumor-associated macrophages (TAMs) form an interconnected cellular supportive network in anaplastic thyroid carcinoma
    Bernard Caillou
    Department of Biopathology, Institut Gustave Roussy, Villejuif, France
    PLoS ONE 6:e22567. 2011
    ..TAMs (type M2) have been recognized as promoting tumor growth. The purpose of our study was to analyze with immunohistochemistry the presence of TAMs in a series of 27 ATC...
  50. doi request reprint FDG PET in the management of patients with adrenal masses and adrenocortical carcinoma
    Desiree Deandreis
    Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy, Villejuif, France
    Horm Cancer 2:354-62. 2011
    ..New tracers and indications for the clinical use of FDG PET in this specific disease still have to be evaluated to assess its role in clinical practice...
  51. doi request reprint Transcatheter arterial chemoembolization for liver metastases in patients with adrenocortical carcinoma
    Julien Cazejust
    Department of Interventional Radiology, Institut Gustave Roussy, 39 rue Camille Desmoulins, Villejuif 94805, France
    J Vasc Interv Radiol 21:1527-32. 2010
    ..To retrospectively evaluate the effectiveness, tolerance, and predictors of response to transcatheter arterial chemoembolization for treatment of liver metastases from adrenocortical carcinoma...
  52. ncbi request reprint Radiation exposure and familial aggregation of cancers as risk factors for colorectal cancer after radioiodine treatment for thyroid carcinoma
    Carole Rubino
    National Institute of Public Health and Medical Research, INSERM, Unit 605, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France
    Int J Radiat Oncol Biol Phys 62:1084-9. 2005
    ..The aim of this study in thyroid cancer patients was to evaluate the role of familial factors in the risk of colorectal cancer and their potential interaction with radioiodine exposure...
  53. ncbi request reprint Detection of liver metastases from endocrine tumors: a prospective comparison of somatostatin receptor scintigraphy, computed tomography, and magnetic resonance imaging
    Clarisse Dromain
    Department of Radiology, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    J Clin Oncol 23:70-8. 2005
    ..To define predictive factors for "high-sensitivity SRS."..
  54. doi request reprint Mitotane, metyrapone, and ketoconazole combination therapy as an alternative to rescue adrenalectomy for severe ACTH-dependent Cushing's syndrome
    Peter Kamenicky
    Faculte de Medecine Paris Sud, Unité Mixte de Recherche S693, and Institut National de la Santé et de la Recherche Médicale Unité 693, Universite Paris Sud, Le Kremlin Bicêtre F 94276, France
    J Clin Endocrinol Metab 96:2796-804. 2011
    ..Mitotane combined with fast-acting steroidogenesis inhibitors might avoid the need for emergency bilateral adrenalectomy in patients with severe hypercortisolism...
  55. ncbi request reprint Follicular-cell derived thyroid cancer in children
    Sophie Leboulleux
    Service de Medecine Nucleaire, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Eur J Cancer 40:1655-9. 2004
    ..Long term prognosis is favorable, but a few deaths have been reported some decades after initial treatment. Adverse prognostic indicators are younger age at discovery and presence of distant metastases...
  56. ncbi request reprint Poorly differentiated follicular thyroid carcinoma: prognostic factors and relevance of histological classification
    Melania Pulcrano
    Nuclear Medicine and Endocrine Oncology, Commissariat à l Energie Atomique LRC29V, Institut Gustave Roussy and University Paris Sud, Villejuif, France
    Thyroid 17:639-46. 2007
    ....
  57. ncbi request reprint Follicular cell-derived thyroid cancer in children
    Sophie Leboulleux
    Institut Gustave Roussy, Villejuif, France
    Horm Res 63:145-51. 2005
    ..The aim of initial treatment should be the total removal of neoplastic foci with a minimal morbidity. Some cancer-related deaths have been reported decades after initial treatment...
  58. ncbi request reprint Clinical review: Current concepts in the management of unilateral recurrent laryngeal nerve paralysis after thyroid surgery
    Dana M Hartl
    Department of Otolaryngology and Head and Neck Surgery, Institut Gustave Roussy, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    J Clin Endocrinol Metab 90:3084-8. 2005
    ..This study was designed to provide an update on the pathophysiological concepts and patient management in a common complication of thyroid surgery, unilateral recurrent laryngeal nerve paralysis (URLNP)...
  59. doi request reprint [Refractory thyroid cancers]
    Martin Schlumberger
    Institut Gustave Roussy, Universite Paris Sud, Service de médecine nucléaire et d oncologie endocrinienne, 94805 Villejuif Cedex, France
    Presse Med 40:1189-98. 2011
    ..Their toxicity is significant and these treatments should be given only to selected patients with locally advanced or metastatic disease, with progression or with clinical symptoms...
  60. ncbi request reprint Prognostic parameters of metastatic adrenocortical carcinoma
    Guillaume Assie
    Service de Médecine Nucléaire et de Cancérologie Endocrinienne, Institut Gustave Roussy, Universite Paris XI, 94800 Villejuif, France
    J Clin Endocrinol Metab 92:148-54. 2007
    ..Prognostic parameters of metastatic adrenocortical carcinoma (ACC) are poorly characterized...
  61. doi request reprint Frequency and intensity of pain related to thyroid nodule fine-needle aspiration cytology
    Sophie Leboulleux
    1 Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy, University Paris Sud, Villejuif, France
    Thyroid 23:1113-8. 2013
    ..Conclusions: FNAC-related pain is frequent and correlates with the number of nodules biopsied, age under 25 years, female sex, and anxiety. ..
  62. doi request reprint Are G3 ENETS neuroendocrine neoplasms heterogeneous?
    Fritz Line Velayoudom-Cephise
    Departments of Nuclear Medicine and Endocrine Oncology Pathology, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France Department of Biostatistics and Epidemiology, Research Group ECM, University Hospital of Pointe à Pitre, Guadeloupe, France Departments of Gastroenterology Thoracic Oncology Digestive Surgery Medical Imaging, Institut Gustave Roussy, Villejuif, France Faculté de Médecine Paris Sud, Université Paris 11, Le Kremlin Bicetre, France
    Endocr Relat Cancer 20:649-57. 2013
    ..If confirmed, future classifications may consider splitting them into two groups according to their morphological differentiation. ..
  63. ncbi request reprint Radioiodine therapy for papillary and follicular thyroid carcinoma
    Michele Klain
    Department of Nuclear Medicine and Commissariat à l Energie Atomique LRC 29V, Institut Gustave Roussy, 94805 Villejuif Cedex, France
    Eur J Nucl Med Mol Imaging 29:S479-85. 2002
    ..It should be used selectively, i.e. only in those patients for whom a clinical benefit may be expected...
  64. ncbi request reprint Prospective study of bone marrow infiltration in aggressive lymphoma by three independent methods: whole-body MRI, PET/CT and bone marrow biopsy
    Vincent Ribrag
    Department of Medicine, Institut Gustave Roussy, Villejuif, France
    Eur J Radiol 66:325-31. 2008
    ..The aim of this study was to compare the performance of BMB, whole-body MRI and PET/CT for evaluation of BM infiltration...
  65. ncbi request reprint Trans-catheter arterial chemoembolization as first-line treatment for hepatic metastases from endocrine tumors
    Alain Roche
    Service de Radiologie Interventionnelle, Institut Gustave Roussy, rue Camille Desmoulins 39, 94805 Villejuif Cedex, France
    Eur Radiol 13:136-40. 2003
    ..Long-term palliation is possible in unresectable liver metastases from digestive neuroendocrine tumors with a few sessions of TACE as first-line and eventually exclusive treatment...
  66. doi request reprint Phase II study of plitidepsin 3-hour infusion every 2 weeks in patients with unresectable advanced medullary thyroid carcinoma
    Eric Baudin
    Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy, Villejuif, France
    Am J Clin Oncol 33:83-8. 2010
    ..v.) infusion every 2 weeks in patients with unresectable advanced medullary thyroid carcinoma (MTC)...
  67. ncbi request reprint Is stimulation of thyroglobulin (Tg) useful in low-risk patients with thyroid carcinoma and undetectable Tg on thyroxin and negative neck ultrasound?
    Martin Schlumberger
    Institut Gustave Roussy, 94805 Villejuif Cedex, France
    Clin Endocrinol (Oxf) 62:119-20. 2005
  68. doi request reprint Endocrine effects of the tyrosine kinase inhibitor vandetanib in patients treated for thyroid cancer
    Maryse Brassard
    Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy, Villejuif 94800, France
    J Clin Endocrinol Metab 96:2741-9. 2011
    ....
  69. ncbi request reprint Imaging of the distribution of (90)y-ibritumomab tiuxetan in bone marrow and comparison with pathology
    Jeremy Coulot
    Department of Physics, Institut Gustave Roussy, Villejuif, France
    Cancer Biother Radiopharm 22:665-71. 2007
    ..Describing the actual distribution of the radionuclide at the level of particles range may have important impact on patient dosimetry and therapy treatment planning...
  70. doi request reprint Serum thyroglobulin determination in thyroid cancer patients
    Zelia Francis
    Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy, University Paris Sud XI, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Best Pract Res Clin Endocrinol Metab 22:1039-46. 2008
    ..Modern methods with an improved functional sensitivity may facilitate its use during follow-up...
  71. ncbi request reprint New therapeutic approaches for metastatic thyroid carcinoma
    Eric Baudin
    Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy, and Faculté de Médecine Paris Sud, Villejuif, France
    Lancet Oncol 8:148-56. 2007
    ..However, the recent availability of molecularly targeted treatments has led to changes in the treatment strategy for DTC in patients with distant metastases, especially in those who are resistant to radioiodine treatment...
  72. ncbi request reprint Molecular epidemiology of thyroid cancer
    Martin Schlumberger
    Service de Medecine Nucleaire, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France
    Cancer Treat Res 122:107-20. 2004
  73. ncbi request reprint Familial medullary thyroid carcinoma: clinical variability and low aggressiveness associated with RET mutation at codon 804
    Francesca Lombardo
    Départment de Biologie Clinique and Service de Médecine Nucléaire, Institut Gustave Roussy, Villejuif, France
    J Clin Endocrinol Metab 87:1674-80. 2002
    ..Indeed, our data should be confirmed on a larger series of V804L carriers, but may offer a balanced strategy to keep under control and prevent development of the full disease phenotype...
  74. doi request reprint Assessment of the cost of fine-needle aspiration cytology as a diagnostic tool in patients with thyroid nodules
    Isabelle Borget
    Department of Health Economics, Institut de Cancerologie Gustave Roussy, University Paris Sud 11, Villejuif, France
    Am J Clin Pathol 129:763-71. 2008
    ..5%, to euros 738. Cost depends on cytopathologist performance and the unsatisfactory rate. In the future, routine ultrasound guidance and on-site assessment of cytopathologic adequacy would help reduce costs...
  75. ncbi request reprint MR imaging of hepatic metastases caused by neuroendocrine tumors: comparing four techniques
    Clarisse Dromain
    Department of Imaging, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
    AJR Am J Roentgenol 180:121-8. 2003
    ..The aim of our prospective study was to assess the MR imaging characteristics of hepatic metastases of neuroendocrine tumors and to determine the optimal MR sequence for their detection...