Christophe Rusniok

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. pmc Reductive evolution in Streptococcus agalactiae and the emergence of a host adapted lineage
    Isabelle Rosinski-Chupin
    Unité de Biologie des Bactéries Pathogènes à Gram Positif, 28 rue du Docteur Roux, Paris Cedex 15, France
    BMC Genomics 14:252. 2013
  2. pmc Comparative genomics and transcriptomics of lineages I, II, and III strains of Listeria monocytogenes
    Torsten Hain
    Institute of Medical Microbiology, Justus Liebig University, Schubertstrasse 81, Giessen, D 35392, Germany
    BMC Genomics 13:144. 2012
  3. pmc NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitidis
    Christophe Rusniok
    Génomique des Microorganismes Pathogènes, Institut Pasteur, rue du Dr Roux, Paris 75015, France
    Genome Biol 10:R110. 2009
  4. pmc Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis
    Christophe Rusniok
    Institut Pasteur, Unité de Biologie des Bactéries Intracellulaires, CNRS URA 2171, Paris, France
    J Bacteriol 192:2266-76. 2010
  5. ncbi request reprint Specific regions of genome plasticity and genetic diversity of the commensal Escherichia coli A0 34/86
    Jana Hejnova
    Unité de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28 rue du Dr Roux, F 75724 Paris, France
    Int J Med Microbiol 296:541-6. 2006
  6. ncbi request reprint Genomic diversity and evolution within the species Streptococcus agalactiae
    Mathieu Brochet
    Unité de Génomique des Microorganismes Pathogènes URA CNRS 2171, Institut Pasteur, 25 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France
    Microbes Infect 8:1227-43. 2006
  7. pmc Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease
    Christel Cazalet
    Institut Pasteur, Biologie des Bactéries Intracellulaires, CNRS URA 2171, Paris, France
    PLoS Genet 6:e1000851. 2010
  8. doi request reprint Deep sequencing defines the transcriptional map of L. pneumophila and identifies growth phase-dependent regulated ncRNAs implicated in virulence
    Tobias Sahr
    Institut Pasteur, 28, rue du Dr Roux, Paris 75724, France
    RNA Biol 9:503-19. 2012
  9. doi request reprint Atypical association of DDE transposition with conjugation specifies a new family of mobile elements
    Mathieu Brochet
    Institut Pasteur, Unité de Génétique des Génomes Bactériens, CNRS URA 2171, France
    Mol Microbiol 71:948-59. 2009
  10. doi request reprint Genome sequence of Vibrio splendidus: an abundant planctonic marine species with a large genotypic diversity
    Frédérique Le Roux
    Institut Pasteur, Unité Plasticité du Génome Bactérien, CNRS URA 2171, F 75015, Paris, France
    Environ Microbiol 11:1959-70. 2009

Collaborators

Detail Information

Publications20

  1. pmc Reductive evolution in Streptococcus agalactiae and the emergence of a host adapted lineage
    Isabelle Rosinski-Chupin
    Unité de Biologie des Bactéries Pathogènes à Gram Positif, 28 rue du Docteur Roux, Paris Cedex 15, France
    BMC Genomics 14:252. 2013
    ..To decipher the genetic basis for the emergence of these highly virulent GBS strains and of their adaptation to fish, we have analyzed the genomic sequence of seven strains isolated from fish and other poikilotherms...
  2. pmc Comparative genomics and transcriptomics of lineages I, II, and III strains of Listeria monocytogenes
    Torsten Hain
    Institute of Medical Microbiology, Justus Liebig University, Schubertstrasse 81, Giessen, D 35392, Germany
    BMC Genomics 13:144. 2012
    ..monocytogenes. Lineage III, represented by the 4a L99 genome is known to contain strains less virulent for humans...
  3. pmc NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitidis
    Christophe Rusniok
    Génomique des Microorganismes Pathogènes, Institut Pasteur, rue du Dr Roux, Paris 75015, France
    Genome Biol 10:R110. 2009
    ..This holds true for Neisseria meningitidis, one of the most feared human bacterial pathogens that causes meningitis and septicemia...
  4. pmc Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis
    Christophe Rusniok
    Institut Pasteur, Unité de Biologie des Bactéries Intracellulaires, CNRS URA 2171, Paris, France
    J Bacteriol 192:2266-76. 2010
    ....
  5. ncbi request reprint Specific regions of genome plasticity and genetic diversity of the commensal Escherichia coli A0 34/86
    Jana Hejnova
    Unité de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28 rue du Dr Roux, F 75724 Paris, France
    Int J Med Microbiol 296:541-6. 2006
    ..coli strain 536 were all identified in E. coli A0 34/86. This comparative analysis underlines the important genome heterogeneity between E. coli strains...
  6. ncbi request reprint Genomic diversity and evolution within the species Streptococcus agalactiae
    Mathieu Brochet
    Unité de Génomique des Microorganismes Pathogènes URA CNRS 2171, Institut Pasteur, 25 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France
    Microbes Infect 8:1227-43. 2006
    ..The study highlights for the first time that this lineage contains a specific and conserved set of surface proteins, probably accounting for its high capacity to cause infections in newborns...
  7. pmc Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease
    Christel Cazalet
    Institut Pasteur, Biologie des Bactéries Intracellulaires, CNRS URA 2171, Paris, France
    PLoS Genet 6:e1000851. 2010
    ..longbeachae is encapsulated. These species-specific differences may account for the different environmental niches and disease epidemiology of these two Legionella species...
  8. doi request reprint Deep sequencing defines the transcriptional map of L. pneumophila and identifies growth phase-dependent regulated ncRNAs implicated in virulence
    Tobias Sahr
    Institut Pasteur, 28, rue du Dr Roux, Paris 75724, France
    RNA Biol 9:503-19. 2012
    ..pneumophila genome, identified many new ncRNAs and will provide a framework for the understanding of virulence and adaptation properties of L. pneumophila...
  9. doi request reprint Atypical association of DDE transposition with conjugation specifies a new family of mobile elements
    Mathieu Brochet
    Institut Pasteur, Unité de Génétique des Génomes Bactériens, CNRS URA 2171, France
    Mol Microbiol 71:948-59. 2009
    ..The combination of DDE transposition with conjugation implies recombination constraints linked to the physical separation of donor and recipient molecules...
  10. doi request reprint Genome sequence of Vibrio splendidus: an abundant planctonic marine species with a large genotypic diversity
    Frédérique Le Roux
    Institut Pasteur, Unité Plasticité du Génome Bactérien, CNRS URA 2171, F 75015, Paris, France
    Environ Microbiol 11:1959-70. 2009
    ..Those results suggest that marine Vibrio can be a source of antibiotic resistance genes...
  11. pmc Extensive recombination events and horizontal gene transfer shaped the Legionella pneumophila genomes
    Laura Gomez-Valero
    Institut Pasteur, Biologie des Bactéries Intracellulaires, 75724, Paris, France
    BMC Genomics 12:536. 2011
    ....
  12. ncbi request reprint Characterization of the flexible genome complement of the commensal Escherichia coli strain A0 34/86 (O83 : K24 : H31)
    Jana Hejnova
    Unité de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris, France
    Microbiology 151:385-98. 2005
    ..These results highlight the thin line between bacterial 'virulence' and 'fitness' or 'colonization' factors, and question the definition of enterobacterial virulence factors...
  13. pmc Double-stranded RNA adenosine deaminase ADAR-1-induced hypermutated genomes among inactivated seasonal influenza and live attenuated measles virus vaccines
    Rodolphe Suspène
    Molecular Retrovirology Unit, Institut Pasteur, Paris Cedex 15, France
    J Virol 85:2458-62. 2011
    ..The hyperedited mutant frequency, including genomes and antigenomes, was a log greater for influenza virus compared to measles virus, suggesting a greater sensitivity to restriction by ADAR-1...
  14. pmc The SrtA Sortase of Streptococcus agalactiae is required for cell wall anchoring of proteins containing the LPXTG motif, for adhesion to epithelial cells, and for colonization of the mouse intestine
    Lila Lalioui
    Unité de Biologie des Bactéries Pathogènes à Gram Positif, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris, France
    Infect Immun 73:3342-50. 2005
    ..These results demonstrate that LPXTG-containing proteins are involved in cell adhesion and GBS persistence in vivo...
  15. ncbi request reprint Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity
    Christel Cazalet
    Laboratoire de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Institut Pasteur, 28, rue du Dr Roux, 75724 Paris Cedex 15, France
    Nat Genet 36:1165-73. 2004
    ..The genome thus reflects the history and lifestyle of L. pneumophila, a human pathogen of macrophages that coevolved with fresh-water amoebae...
  16. doi request reprint Legionella pneumophila effector RomA uniquely modifies host chromatin to repress gene expression and promote intracellular bacterial replication
    Monica Rolando
    Institut Pasteur, Unité Biologie des Bactéries Intracellulaires, Paris 75015, France
    Cell Host Microbe 13:395-405. 2013
    ..Thus, a secreted L. pneumophila effector targets the host cell nucleus and modifies histones to repress gene expression and promote efficient intracellular replication...
  17. pmc Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions
    Laura Gomez-Valero
    Institut Pasteur, Unité de Biologie des Bactéries Intracellulaires Paris, France
    Front Microbiol 2:208. 2011
    ..Finally, evolutionary aspects regarding the eukaryotic like proteins in Legionella are discussed...
  18. ncbi request reprint Comparison of the genome sequences of Listeria monocytogenes and Listeria innocua: clues for evolution and pathogenicity
    Carmen Buchrieser
    Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 25, rue du Dr Roux, 75724 Paris Cedex 15, France
    FEMS Immunol Med Microbiol 35:207-13. 2003
    ....
  19. ncbi request reprint The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens
    Eric Duchaud
    Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Nat Biotechnol 21:1307-13. 2003
    ..Moreover, newly identified insecticidal proteins may be effective alternatives for the control of insect pests...
  20. pmc Genetic editing of HBV DNA by monodomain human APOBEC3 cytidine deaminases and the recombinant nature of APOBEC3G
    Michel Henry
    Molecular Retrovirology Unit, CNRS URA 3015, Institut Pasteur, Paris, France
    PLoS ONE 4:e4277. 2009
    ..A phylogenic analysis of A3 exons revealed that A3G is in fact a chimera with the first two exons being derived from the A3F gene. This might allow co-expression of the two genes that are able to restrict HIV-1Deltavif efficiently...