Affiliation: Institut Pasteur de Lille
Charrier H, Cuvelliez M, Dubois Deruy E, Mulder P, Richard V, Bauters C, et al
. Integrative System Biology Analyses Identify Seven MicroRNAs to Predict Heart Failure. Noncoding RNA. 2019;5: pubmed publisher
..We identified a signature of 7 microRNAs associated with LVR after MI that support the interest of integrative systems biology analyses to define a miRNA signature of HF progression. ..
Gomes C, Agg B, Andova A, Arslan S, Baker A, Barteková M, et al
. Catalyzing Transcriptomics Research in Cardiovascular Disease: The CardioRNA COST Action CA17129. Noncoding RNA. 2019;5: pubmed publisher
..COST (European Cooperation in Science and Technology) is a funding organization for research and innovation networks (www.cost.eu). ..
Turkieh A, Fertin M, Bouvet M, Mulder P, Drobecq H, Lemesle G, et al
. Expression and Implication of Clusterin in Left Ventricular Remodeling After Myocardial Infarction. Circ Heart Fail. 2018;11:e004838 pubmed publisher
..Our results show for the first time that plasma CLU levels are associated with LVR post-myocardial infarction, have in part a cardiac origin, and are a predictor of early death in heart failure patients. ..
Bouvet M, Turkieh A, Acosta Martin A, Chwastyniak M, Beseme O, Amouyel P, et al
. Proteomic profiling of macrophages by 2D electrophoresis. J Vis Exp. 2014;:e52219 pubmed publisher
..The proteomic approaches described here allows the investigation of the macrophage protein changes associated with various disorders like host pathogenicity or microbial toxins. ..
Spear R, Boytard L, Blervaque R, Chwastyniak M, Hot D, Vanhoutte J, et al
. Adventitial Tertiary Lymphoid Organs as Potential Source of MicroRNA Biomarkers for Abdominal Aortic Aneurysm. Int J Mol Sci. 2015;16:11276-93 pubmed publisher
..Further investigations will be required to evaluate their targets in order to better understand AAA pathophysiology. ..
Pinet F, Cuvelliez M, Kelder T, Amouyel P, Radonjic M, Bauters C. Integrative network analysis reveals time-dependent molecular events underlying left ventricular remodeling in post-myocardial infarction patients. Biochim Biophys Acta Mol Basis Dis. 2017;1863:1445-1453 pubmed publisher
Dubois Deruy E, Belliard A, Mulder P, Bouvet M, Smet Nocca C, Janel S, et al
. Interplay between troponin T phosphorylation and O-N-acetylglucosaminylation in ischaemic heart failure. Cardiovasc Res. 2015;107:56-65 pubmed publisher
..Modulation of these post-translational modifications of TnT may be a new therapeutic strategy in HF. ..
Dubois Deruy E, Cuvelliez M, Fiedler J, Charrier H, Mulder P, Hebbar E, et al
. MicroRNAs regulating superoxide dismutase 2 are new circulating biomarkers of heart failure. Sci Rep. 2017;7:14747 pubmed publisher
..Circulating levels of the 3 miRNAs and their target SOD2 were associated with high LVR post-MI in REVE-2 patients. We demonstrated for the first time the potential of microRNAs regulating SOD2 as new circulating biomarkers of HF. ..