Affiliation: Institut National Agronomique Paris-Grignon
- A statistical approach for array CGH data analysisFranck Picard
Institut National Agronomique Paris Grignon, UMR INAPG ENGREF INRA MIA 518, Paris, France
BMC Bioinformatics 6:27. 2005..Two major problems arise: to determine which parameters are affected by the abrupt changes (the mean and the variance, or the mean only), and the selection of the number of segments in the profile...
- A segmentation/clustering model for the analysis of array CGH dataF Picard
UMR INA P G ENGREF INRA MIA 518, Paris, France
Biometrics 63:758-66. 2007..We compare our method to segmentation methods and to hidden Markov models, and we show that the new segmentation/clustering model is a promising alternative that can be applied in the more general context of signal processing...
- Evidence for digenic inheritance in a family with both febrile convulsions and temporal lobe epilepsy implicating chromosomes 18qter and 1q25-q31S Baulac
INSERM U289, Hĵpital de la Pitié Salpêtrière, Paris, France
Ann Neurol 49:786-92. 2001..This family suggests that the association between FC and TLE may be observed in the absence of hippocampal structural abnormalities and that they may have, in some cases, a common genetic basis...
- Melanocortin 4 receptor mutations in a large cohort of severely obese adults: prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eatingCecile Lubrano-Berthelier
Diabetes Center and Department of Medicine, University of California San Francisco, San Francisco, California 94143 0573, USA
J Clin Endocrinol Metab 91:1811-8. 2006..There are conflicting reports regarding the prevalence, nature, and pathogenic effects of MC4R mutations in adults with severe late-onset obesity...