José Osorio y Fortéa

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. ncbi request reprint AffyGCQC: a web-based interface to detect outlying genechips with extreme studentized deviate tests
    José Osorio y Fortéa
    Unité d Immunophysiologie et Parasitisme Intracellulaire, Département de Parasitologie et Mycologie, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris, France
    J Bioinform Comput Biol 6:317-34. 2008
  2. pmc Transcriptional signatures of BALB/c mouse macrophages housing multiplying Leishmania amazonensis amastigotes
    José Osorio y Fortéa
    Institut Pasteur, Unité d Immunophysiologie et Parasitisme Intracellulaire, Département de Parasitologie et Mycologie, Paris, France
    BMC Genomics 10:119. 2009
  3. ncbi request reprint Unveiling pathways used by Leishmania amazonensis amastigotes to subvert macrophage function
    José Osorio y Fortéa
    Département de Parasitologie et Mycologie, Unité d Immunophysiologie et Parasitisme Intracellulaire, Institut Pasteur, Paris, France
    Immunol Rev 219:66-74. 2007
  4. doi request reprint Sorting of Leishmania-bearing dendritic cells reveals subtle parasite-induced modulation of host-cell gene expression
    Hervé Lecoeur
    Institut Pasteur, Unité d Immunophysiologie et Parasitisme Intracellulaire, Département de Parasitologie et Mycologie, Paris Cedex 15, France
    Microbes Infect 12:46-54. 2010
  5. doi request reprint Identification of Leishmania-specific protein phosphorylation sites by LC-ESI-MS/MS and comparative genomics analyses
    Sonia Hem
    Institut Pasteur, Plate forme de Protéomique and CNRS URA 2185, Department of Structural Biology and Chemistry, Pasteur Genopole Ile de France, Paris, France
    Proteomics 10:3868-83. 2010
  6. pmc Early over expression of messenger RNA for multiple genes, including insulin, in the Pancreatic Lymph Nodes of NOD mice is associated with Islet Autoimmunity
    Béatrice Regnault
    Immunophysiology and Intracellular Parasitism Unit, Department of Parasitology and Mycology, 75015 Paris, France
    BMC Med Genomics 2:63. 2009
  7. pmc Phosphoproteome dynamics reveal heat-shock protein complexes specific to the Leishmania donovani infectious stage
    Miguel A Morales
    Institut Pasteur, G5 Virulence Parasitaire, 75015 Paris, France
    Proc Natl Acad Sci U S A 107:8381-6. 2010

Collaborators

Detail Information

Publications7

  1. ncbi request reprint AffyGCQC: a web-based interface to detect outlying genechips with extreme studentized deviate tests
    José Osorio y Fortéa
    Unité d Immunophysiologie et Parasitisme Intracellulaire, Département de Parasitologie et Mycologie, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris, France
    J Bioinform Comput Biol 6:317-34. 2008
    ..AffyGCQC has been designed as an easy-to-use Web-based interface (online supplementary information: http://www.transcriptome.ens.fr/AffyGCQC/; contact: affygcqc@biologie.ens.fr)...
  2. pmc Transcriptional signatures of BALB/c mouse macrophages housing multiplying Leishmania amazonensis amastigotes
    José Osorio y Fortéa
    Institut Pasteur, Unité d Immunophysiologie et Parasitisme Intracellulaire, Département de Parasitologie et Mycologie, Paris, France
    BMC Genomics 10:119. 2009
    ..Indeed, the intracellular development of L. amazonensis amastigote relies on the biogenesis and dynamic remodelling of a phagolysosome, termed the parasitophorous vacuole, primarily within dermal MPhi...
  3. ncbi request reprint Unveiling pathways used by Leishmania amazonensis amastigotes to subvert macrophage function
    José Osorio y Fortéa
    Département de Parasitologie et Mycologie, Unité d Immunophysiologie et Parasitisme Intracellulaire, Institut Pasteur, Paris, France
    Immunol Rev 219:66-74. 2007
    ..that persist within the mammalian dermis reach a non-replicating developmental stage? If so, is this developmental stage the only one displaying the features required for further development as promastigotes within the sand fly gut lumen?..
  4. doi request reprint Sorting of Leishmania-bearing dendritic cells reveals subtle parasite-induced modulation of host-cell gene expression
    Hervé Lecoeur
    Institut Pasteur, Unité d Immunophysiologie et Parasitisme Intracellulaire, Département de Parasitologie et Mycologie, Paris Cedex 15, France
    Microbes Infect 12:46-54. 2010
    ..In conclusion, this approach provides a powerful method for further characterisation, of amastigote-hosting DCs in the skin and the skin-draining lymph nodes...
  5. doi request reprint Identification of Leishmania-specific protein phosphorylation sites by LC-ESI-MS/MS and comparative genomics analyses
    Sonia Hem
    Institut Pasteur, Plate forme de Protéomique and CNRS URA 2185, Department of Structural Biology and Chemistry, Pasteur Genopole Ile de France, Paris, France
    Proteomics 10:3868-83. 2010
    ..These unique phosphorylation sites reveal important differences between host and parasite biology and post-translational protein regulation, which may be exploited for the design of novel anti-parasitic interventions...
  6. pmc Early over expression of messenger RNA for multiple genes, including insulin, in the Pancreatic Lymph Nodes of NOD mice is associated with Islet Autoimmunity
    Béatrice Regnault
    Immunophysiology and Intracellular Parasitism Unit, Department of Parasitology and Mycology, 75015 Paris, France
    BMC Med Genomics 2:63. 2009
    ..Analysis of gene expression profiles has the potential to provide a global understanding of the disease and to generate novel hypothesis concerning the initiation of the autoimmune process...
  7. pmc Phosphoproteome dynamics reveal heat-shock protein complexes specific to the Leishmania donovani infectious stage
    Miguel A Morales
    Institut Pasteur, G5 Virulence Parasitaire, 75015 Paris, France
    Proc Natl Acad Sci U S A 107:8381-6. 2010
    ..Phosphorylation of the major Leishmania chaperones at the pathogenic stage suggests that these proteins may be promising drug targets via inhibition of their respective protein kinases...