Research Topics
Genomes and Genes | Serge MostowySummaryAffiliation: Institut Pasteur Country: France Publications
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Detail Information
Publications
p62 and NDP52 proteins target intracytosolic Shigella and Listeria to different autophagy pathwaysSerge Mostowy
Institut Pasteur, Unité des Interactions Bactéries Cellules, Paris F 75015, France
J Biol Chem 286:26987-95. 2011..These data provide a new molecular framework to understand the emerging complexity of autophagy and its ability to achieve specific clearance of intracytosolic bacteria...
Entrapment of intracytosolic bacteria by septin cage-like structuresSerge Mostowy
Unité des Interactions Bactéries Cellules, Institut Pasteur, Paris F 75015, France
Cell Host Microbe 8:433-44. 2010..Finally, we show that septin cages entrap bacteria targeted to autophagy. Together, these results reveal an unsuspected mechanism of host defense that restricts dissemination of invasive pathogens...
Autophagy and the cytoskeleton: new links revealed by intracellular pathogensSerge Mostowy
Institut Pasteur, Unité des Interactions Bactéries Cellules, Paris, France
Autophagy 7:780-2. 2011..Understanding the role of septins, a so far poorly characterized component of the cytoskeleton, will thus provide new insights into bacterial infection and autophagy...
Septin 11 restricts InlB-mediated invasion by ListeriaSerge Mostowy
Unité des Interactions Bactéries Cellules, Institut Pasteur, Paris F 75015, France
J Biol Chem 284:11613-21. 2009..Because SEPT2 is essential for the InlB-mediated entry of Listeria, but SEPT11 is not, our findings distinguish the roles of different mammalian septins...
A role for septins in the interaction between the Listeria monocytogenes INVASION PROTEIN InlB and the Met receptorSerge Mostowy
Unité des Interactions Bactéries Cellules, Institut Pasteur, Paris, France
Biophys J 100:1949-59. 2011..Septins are therefore likely to participate in anchorage of the Met receptor to the actin cytoskeleton, and represent a critical determinant in surface receptor function...
Cytoskeleton rearrangements during Listeria infection: clathrin and septins as new players in the gameSerge Mostowy
Institut Pasteur, Département de Biologie Cellulaire et Infection, Unité des Interactions Bactéries Cellules, Paris, F 75015 France
Cell Motil Cytoskeleton 66:816-23. 2009..The challenge is now to decipher how all of these components orchestrate themselves to permit entry into normally non-phagocytic cells...
Recruitment of the major vault protein by InlK: a Listeria monocytogenes strategy to avoid autophagyLaurent Dortet
Institut Pasteur, Unité des Interactions Bactéries Cellules, Paris, France
PLoS Pathog 7:e1002168. 2011..Together these results reveal that MVP is hijacked by L. monocytogenes in order to counteract the autophagy process, a finding that could have major implications in deciphering the cellular role of vault particles...
Listeria and autophagy escape: involvement of InlK, an internalin-like proteinLaurent Dortet
Institut Pasteur, Unité des Interactions Bactéries Cellules, Paris, France
Autophagy 8:132-4. 2012..Understanding the role of MVP may provide new insights into bacterial infection and autophagy...
Virulence factors that modulate the cell biology of Listeria infection and the host responseSerge Mostowy
Institut Pasteur, Unité des Interactions Bactéries Cellules, Paris, France
Adv Immunol 113:19-32. 2012..This review will update our knowledge of Listeria virulence factors and highlight their role during the Listeria infection process...
Septins as key regulators of actin based processes in bacterial infectionSerge Mostowy
Institut Pasteur, Unité des Interactions Bactéries Cellules, Paris, France
Biol Chem 392:831-5. 2011..The challenge now is to decipher the precise role of septins during actin rearrangements and how these different cytoskeleton components orchestrate infection processes...
Septins: the fourth component of the cytoskeletonSerge Mostowy
Institut Pasteur, Unité des Interactions Bactéries Cellules, Département de Biologie Cellulaire et Infection, F 75015 Paris, France
Nat Rev Mol Cell Biol 13:183-94. 2012....
Bacterial autophagy: restriction or promotion of bacterial replication?Serge Mostowy
Institut Pasteur, Unité des Interactions Bactéries Cellules, Département de Biologie Cellulaire et Infection, F 75015 Paris, France
Trends Cell Biol 22:283-91. 2012..A complete understanding of bacterial autophagy in vivo shall be critical to exploit autophagy and its therapeutic potential...
Septins regulate bacterial entry into host cellsSerge Mostowy
Institut Pasteur, Unité des Interactions Bactéries Cellules, Paris, France
PLoS ONE 4:e4196. 2009..We previously identified SEPT9 associated with phagosomes containing latex beads coated with the Listeria surface protein InlB...
