Cl Monneret

Summary

Affiliation: Institut Curie
Country: France

Publications

  1. doi request reprint [Four new drugs on the market: abiraterone, belatacept, vandetanib and fidaxomycine]
    C Monneret
    Institut Curie, 26, rue d Ulm, 75248 Paris Cedex 05, France
    Ann Pharm Fr 71:95-103. 2013
  2. doi request reprint Platinum anticancer drugs. From serendipity to rational design
    C Monneret
    Institut Curie, 26, rue d Ulm, 75248 Paris Cedex 05, France
    Ann Pharm Fr 69:286-95. 2011
  3. ncbi request reprint Synthesis and antitumour activity of a new series of nitrosoureido sugars
    C Monneret
    Laboratoire de Pharmacochimie, unité mixte 176 CNRS Institut Curie, 26, rue d Ulm, F 75248, Paris, France
    Eur J Med Chem 35:137-46. 2000
  4. ncbi request reprint [A new therapy with bortezomib, an oncologic medicinal product of the year 2004]
    Cl Monneret
    Departement de Pharmacochimie, Institut Curie, Paris
    Ann Pharm Fr 63:343-9. 2005
  5. ncbi request reprint [Glycochemistry and therapeutics. Introduction]
    C Monneret
    Département de chimie thérapeutique Umr 176 Cnrs IC, 26, rue d Ulm, F 75248 Paris Cedex 05
    Ann Pharm Fr 65:3-4. 2007
  6. ncbi request reprint Histone deacetylase inhibitors for epigenetic therapy of cancer
    Claude Monneret
    Department of Medicinal Chemistry, Institut Curie, Paris, France
    Anticancer Drugs 18:363-70. 2007
  7. doi request reprint [Contaminated heparins]
    C Monneret
    UMR 176, Section de Recherche, Institut Curie, 26, rue d Ulm, 75248 Paris Cedex 05, France
    Ann Pharm Fr 66:212-5. 2008
  8. doi request reprint [Prohibit or not bisphenol-A?]
    C Monneret
    UMR 176, Section de Recherche, Institut Curie, 26, rue d Ulm, 75248 Paris Cedex 05, France
    Ann Pharm Fr 68:99-103. 2010
  9. doi request reprint [Current impact of natural products in the discovery of anticancer drugs]
    C Monneret
    Laboratoire de pharmaco chimie, UMR 176, Institut Curie, 26, 75248 Paris Cedex, France
    Ann Pharm Fr 68:218-32. 2010
  10. ncbi request reprint Histone deacetylase inhibitors
    Claude Monneret
    Laboratoire de Pharmacochimie, unité mixte 176 CNRS IC, Institut Curie, section de recherche 26, rue d Ulm, 75248 Paris Cedex 05, France
    Eur J Med Chem 40:1-13. 2005

Collaborators

  • Frédéric Schmidt
  • P B Arimondo
  • Rudi Pauwels
  • N Osheroff
  • Marie Carriere
  • Daniel Scherman
  • Laurence Kraus Berthier
  • Abdellah Benjahad
  • Maria Duca
  • Jean Claude Florent
  • Daniel Dauzonne
  • Bruno Pfeiffer
  • Stephane Leonce
  • Pierre Renard
  • Dominique Guianvarc'h
  • Alain Pierre
  • Philippe Meresse
  • Abdessamad El Alaoui
  • Emmanuel Roulland
  • Julia Kaffy
  • Jean Guillaumel
  • Sylvie Thirot
  • Emmanuel Bertounesque
  • Emmanuel Bouvier
  • Kahina Oussedik
  • Ludovic Halby
  • Renée Pontikis
  • E Bouvier
  • Laurence Kraus-Berthier
  • Cyrille Kuhn
  • Brigitte Bauvois
  • Stéphane Angenault
  • Prokopios Magiatis
  • Nabendu Saha
  • Daniele Carrez
  • Alain Croisy
  • Carine Giovannangeli
  • Anna Garbesi
  • Jian Sheng Sun
  • Alexandre Ceccaldi
  • Jean Claude Madelmont
  • Chawki Boukarim
  • Elsa Dechaux
  • Jean Bernard Bongui
  • Marie Line Puiffe
  • Sandrine Paillat
  • Laure Peruchon
  • Caroline Bennejean

Detail Information

Publications35

  1. doi request reprint [Four new drugs on the market: abiraterone, belatacept, vandetanib and fidaxomycine]
    C Monneret
    Institut Curie, 26, rue d Ulm, 75248 Paris Cedex 05, France
    Ann Pharm Fr 71:95-103. 2013
    ..Fidaxomicin has minimal activity against Bacteroides species, which may be advantageous in maintaining colonization resistance and protecting the gastrointestinal tract from colonization by C. difficile...
  2. doi request reprint Platinum anticancer drugs. From serendipity to rational design
    C Monneret
    Institut Curie, 26, rue d Ulm, 75248 Paris Cedex 05, France
    Ann Pharm Fr 69:286-95. 2011
    ....
  3. ncbi request reprint Synthesis and antitumour activity of a new series of nitrosoureido sugars
    C Monneret
    Laboratoire de Pharmacochimie, unité mixte 176 CNRS Institut Curie, 26, rue d Ulm, F 75248, Paris, France
    Eur J Med Chem 35:137-46. 2000
    ..Owing to its lower acute toxicity, methyl 3-[3-(2-chloroethyl)-3-nitrosoureido]-3, 4-dideoxy-beta-D-arabino-hexopyranoside 24 appeared as the best candidate for preclinical studies...
  4. ncbi request reprint [A new therapy with bortezomib, an oncologic medicinal product of the year 2004]
    Cl Monneret
    Departement de Pharmacochimie, Institut Curie, Paris
    Ann Pharm Fr 63:343-9. 2005
    ..The same year 2004, the Nobel Prize in chemistry was awarded to three researchers "for the discovery of ubitiquin-mediated protein degradation", a regulated process by which proteins are cleaved into peptides inside cells...
  5. ncbi request reprint [Glycochemistry and therapeutics. Introduction]
    C Monneret
    Département de chimie thérapeutique Umr 176 Cnrs IC, 26, rue d Ulm, F 75248 Paris Cedex 05
    Ann Pharm Fr 65:3-4. 2007
  6. ncbi request reprint Histone deacetylase inhibitors for epigenetic therapy of cancer
    Claude Monneret
    Department of Medicinal Chemistry, Institut Curie, Paris, France
    Anticancer Drugs 18:363-70. 2007
    ....
  7. doi request reprint [Contaminated heparins]
    C Monneret
    UMR 176, Section de Recherche, Institut Curie, 26, rue d Ulm, 75248 Paris Cedex 05, France
    Ann Pharm Fr 66:212-5. 2008
    ..The strict respect of the pharmaceutical chain is urgently required to avoid any kind of quality problem in the future...
  8. doi request reprint [Prohibit or not bisphenol-A?]
    C Monneret
    UMR 176, Section de Recherche, Institut Curie, 26, rue d Ulm, 75248 Paris Cedex 05, France
    Ann Pharm Fr 68:99-103. 2010
    ..More generally, the human health risks that may be associated with low-level but constant exposures to EDC and BPA in particular, are still largely unknown and highly controversial...
  9. doi request reprint [Current impact of natural products in the discovery of anticancer drugs]
    C Monneret
    Laboratoire de pharmaco chimie, UMR 176, Institut Curie, 26, 75248 Paris Cedex, France
    Ann Pharm Fr 68:218-32. 2010
    ....
  10. ncbi request reprint Histone deacetylase inhibitors
    Claude Monneret
    Laboratoire de Pharmacochimie, unité mixte 176 CNRS IC, Institut Curie, section de recherche 26, rue d Ulm, 75248 Paris Cedex 05, France
    Eur J Med Chem 40:1-13. 2005
    ..Simultaneously, synthetic benzamide-containing HDACs were reported and two of them, MS-275 and CI-994, have reached phase II and I clinical trials, respectively...
  11. ncbi request reprint Novel carbamate derivatives of 4-beta-amino-4'-O-demethyl-4-desoxypodophyllotoxin as inhibitors of topoisomerase II: synthesis and biological evaluation
    Maria Duca
    UMR 176 CNRS, Institut Curie, Section de Recherche, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    Org Biomol Chem 3:1074-80. 2005
    ..Compounds 4a-c, 4g, 4j and 4k are topoisomerase II poisons that induce double-stranded breaks in DNA and exhibit increased cytotoxicity compared to etoposide...
  12. ncbi request reprint New Taxol (paclitaxel) prodrugs designed for ADEPT and PMT strategies in cancer chemotherapy
    Abdessamad El Alaoui
    UMR 176 CNRS Institut Curie, Centre de Recherche, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    Bioorg Med Chem 14:5012-9. 2006
    ..The arylamino spacer-containing prodrug, more stable than the corresponding nitro analogue, was selected for further studies...
  13. ncbi request reprint A new paclitaxel prodrug for use in ADEPT strategy
    Emmanuel Bouvier
    UMR 176 CNRS Institut Curie, Section Recherche 26 rue d Ulm, 75248 Paris Cedex 05, France
    Org Biomol Chem 1:3343-52. 2003
    ..Indeed, this new prodrug proved to be activated significantly faster than a former paclitaxel prodrug containing a conventional spacer...
  14. ncbi request reprint Isoxazole-type derivatives related to combretastatin A-4, synthesis and biological evaluation
    Julia Kaffy
    CNRS, UMR 176, Institut Curie, Centre de Recherche, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    Bioorg Med Chem 14:4067-77. 2006
    ..These data showed that minor alteration in the chemical structure of the heterocyclic ring and its relative orientation with regard to the two phenyl rings of CA4 could dramatically influence the tubulin binding properties...
  15. ncbi request reprint Synthesis and biological activity of 6H-isoindolo[2,1-a]indol-6-ones, analogues of batracylin, and related compounds
    Jean Guillaumel
    Service de Pharmacochimie, UMR 176 CNRS Institut Curie, Paris, France
    Eur J Med Chem 41:379-86. 2006
    ..Under the same conditions, the dichloro derivative 13d led to the monoalkyl compound 20 which was the most cytotoxic of the series...
  16. ncbi request reprint Prodrug Mono Therapy: synthesis and biological evaluation of an etoposide glucuronide-prodrug
    Frédéric Schmidt
    UMR 176 CNRS Institut Curie, Section Recherche, 26, rue d Ulm, 75248 Cedex 05, Paris, France
    Bioorg Med Chem 11:2277-83. 2003
    ..In vitro, the prodrug was shown to be less cytotoxic and more water-soluble than etoposide itself. Finally, in the presence of the beta-D-glucuronidase, cleavage of the prodrug with complete release of the drug has been observed...
  17. ncbi request reprint First enzymatically activated Taxotere prodrugs designed for ADEPT and PMT
    Emmanuel Bouvier
    UMR176 CNRS Institut Curie, Section Recherche, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    Bioorg Med Chem 12:969-77. 2004
    ..As docetaxel was efficiently released in both cases, these compounds are very valuable candidates for further biological evaluations...
  18. ncbi request reprint Enantioselective synthesis of 12-amino alkylidenecyclopentenone prostaglandins
    Emmanuel Roulland
    UMR 176 CNRS Institut Curie, Section de Recherche, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    J Org Chem 67:4399-406. 2002
    ..A palladium-catalyzed cross-coupling reaction on a 5-iodo-1,5-diene allowed the synthesis of prostanoids with variable Rw side chains. These new compounds exhibit high cytotoxic activities...
  19. ncbi request reprint Hemi-synthesis and biological activity of new analogues of podophyllotoxin
    Emmanuel Roulland
    Laboratoire de Pharmacochimie, UMR 176 CNRS IC, Section Recherche de l Institut Curie, 26 Rue d Ulm, Paris, France
    Bioorg Med Chem 10:3463-71. 2002
    ..In the latter series, carboxaldehyde- and carboxylic acid-containing derivatives were also synthesized...
  20. ncbi request reprint Etoposide: discovery and medicinal chemistry
    Philippe Meresse
    UMR 176 CNRS Institut Curie, Section de Recherche, 26 Rue d Ulm, 75248 Paris 05, France
    Curr Med Chem 11:2443-66. 2004
    ..The last part is concerned with the search for new etoposide analogs based upon an empirical design...
  21. ncbi request reprint Synthesis and biological evaluation of vinylogous combretastatin A-4 derivatives
    Julia Kaffy
    UMR 176 CNRS, Institut Curie Section de Recherche, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    Org Biomol Chem 3:2657-60. 2005
    ..As compared to CA4, the derivative with a phenyl moiety has shown increased potency in its ability to inhibit tubulin polymerisation...
  22. ncbi request reprint Cancer chemotherapy: a SN-38 (7-ethyl-10-hydroxycamptothecin) glucuronide prodrug for treatment by a PMT (Prodrug MonoTherapy) strategy
    Stéphane Angenault
    UMR176 CNRS Institut Curie, 26, rue d Ulm, 75248 Paris Cedex 05, France
    Bioorg Med Chem Lett 13:947-50. 2003
    ....
  23. ncbi request reprint Synthesis and antiproliferative activity of retroetoposide
    Philippe Meresse
    Laboratoire de Pharmacochimie, UMR 176 CNRS Institut Curie, Section Recherche, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    Bioorg Med Chem Lett 13:4107-9. 2003
    ..Subsequent coupling of 22 with 1-O-trimethylsilyl-4,6-O-ethylidene-beta-D-glucoside 26 afforded retroetoposide 5 which is 10-fold less cytotoxic than etoposide against L1210 cell line...
  24. ncbi request reprint Synthesis and biological evaluation of novel flavone-8-acetic acid derivatives as reversible inhibitors of aminopeptidase N/CD13
    Brigitte Bauvois
    Unite 365 INSERM, Institut Curie, Section de Recherche, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    J Med Chem 46:3900-13. 2003
    ....
  25. ncbi request reprint Synthesis and biological evaluation of new cross-conjugated dienone marine prostanoid analogues
    Cyrille Kuhn
    Institut Curie, Section Recherche, Laboratoire de Pharmacochimie, 26 Rue d Ulm, 75248 Paris, Cedex 05, France
    Org Biomol Chem 2:2028-39. 2004
    ..These simpler compounds (45, 46, 47, 48, 60) are still highly cytotoxic, in the medium range of 60 nM, close to the value of natural punaglandins...
  26. pmc Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotides
    Maria Duca
    UMR 5153, CNRS, Paris, France
    Nucleic Acids Res 34:1900-11. 2006
    ..Finally, drug-TFO conjugates are useful tools to investigate the mechanistic details of topo II poisoning...
  27. ncbi request reprint [Glucuronyl paclitaxel (Taxol) derivatives as tumor activated prodrugs]
    E Bouvier
    UMR 176 CNRS Institut Curie, Laboratoire de Pharmacochimie, Section de Recherche, 26, rue d Ulm, F75248 Paris Cedex 05, France
    Ann Pharm Fr 63:53-62. 2005
    ....
  28. ncbi request reprint Protecting groups for glucuronic acid: application to the synthesis of new paclitaxel (taxol) derivatives
    Abdessamad El Alaoui
    UMR 176 CNRS Institut Curie, Centre de Recherche, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    J Org Chem 71:9628-36. 2006
    ..By using palladium chemistry, an efficient one-step removal of all the allyl groups at the end of the synthesis afforded the desired compounds in good yields...
  29. ncbi request reprint 4-benzyl- and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones, a new family of potent anti-HIV agents: optimization and in vitro evaluation against clinically important HIV mutant strains
    Abdellah Benjahad
    UMR 176 CNRS Institut Curie, Laboratoire de Pharmacochimie, Section de Recherche, Batiment 110, Centre Universitaire, 91405 Orsay, France
    J Med Chem 47:5501-14. 2004
    ..These results form a solid basis for continued optimization of the pyridinone series...
  30. ncbi request reprint 4-Benzyl and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones: in vitro evaluation of new C-3-amino-substituted and C-5,6-alkyl-substituted analogues against clinically important HIV mutant strains
    Abdellah Benjahad
    Laboratoire de Pharmacochimie, Section de Recherche, UMR 176 CNRS Institut Curie, Batiment 110, Centre Universitaire, 91405 Orsay, France
    J Med Chem 48:1948-64. 2005
    ..The preferred mode of binding for compound 62, corresponding to the predicted "orientation 1", was revealed in the X-ray crystal structure of the compound 62-RT complex...
  31. ncbi request reprint Synthesis and antiproliferative activity of basic ethers of 1,2-dihydropyrrolo[1,2-a]indole, 6H-isoindolo[2,1-a]indole, and 6H-benz[5,6]isoindolo[2,1-a]indole
    Jean Guillaumel
    Service de Chimie de l Institut Curie, UMR 176 CNRS, 26 Rue d Ulm, F 75248 Paris Cedex 05, France
    Oncol Res 13:537-49. 2003
    ..Among the monobasic ethers 14a, 14b, 22, and 29, which do not bind to DNA, the pentacyclic analog 29 exhibited micromolar cytotoxic activity against L1210 and HT-29 cell lines and induced a weak topoisomerase II inhibition...
  32. ncbi request reprint Synthesis and biological study of a new series of 4'-demethylepipodophyllotoxin derivatives
    Maria Duca
    Laboratoire de Biophysique, UMR 5153 CNRS, Museum national d histoire naturelle, USM 0503, INSERM UR565, 43 rue Cuvier, 75231 Paris Cedex 05, France
    J Med Chem 48:593-603. 2005
    ..From preliminary in vivo investigation of both compounds against P388 leukemia and orthotopically grafted human A549 lung carcinoma, it appeared that 13a and 27a constitute promising leads for a new class of antitumor agents...
  33. ncbi request reprint Synthesis and biological activity of sulfonamide derivatives of epipodophyllotoxin
    Dominique Guianvarc'h
    Laboratoire de Biophysique, CNRS UMR 5153 MNHN USM 0503, INSERM UR 565, 43 rue Cuvier, 75231 Paris Cedex 05, France
    J Med Chem 47:2365-74. 2004
    ..In vivo, against the P388 leukemia and the A-549 orthotopic model of lung carcinoma, the most promising compounds were the morpholino- and the piperazino-containing sulfonamides derivatives 8r and 8s...
  34. ncbi request reprint Triple helix-forming oligonucleotides conjugated to new inhibitors of topoisomerase II: synthesis and binding properties
    Maria Duca
    Museum national d histoire naturelle, USM0503 MNHN, UMR5153 CNRS, U565 INSERM, 43 rue Cuvier CP26 75231 Paris Cedex 05 France
    Bioconjug Chem 16:873-84. 2005
    ..This stabilization effect is more pronounced at the 3' end than at the 5' end. All conjugates form a stable triplex selectively on the DNA target at 37 degrees C and pH 7.2...
  35. ncbi request reprint New synthetic glycolipids for targeted gene transfer: synthesis, formulation in lipoplexes and specific interaction with lectin
    Marie Carriere
    ENSCP CNRS Gencell S A, Vitry sur Seine, France
    Drug Deliv 11:351-63. 2004
    ..Glycolipid-containing lipoplexes gave an efficient gene transfer on hepatocytes, although no ligand-targeted transfection could be observed...