Affiliation: Institut Pasteur de Lille
- Meirhaeghe A, Cottel D, Amouyel P, Dallongeville J. Lack of association between certain candidate gene polymorphisms and the metabolic syndrome. Mol Genet Metab. 2005;86:293-9 pubmed..In conclusion, this study suggests that among a large sample of French men and women, the above named SNPs in UCP3, FATP1, TNF-alpha, LEP, and GNB3 genes are not major contributors to the MS risk. ..
- Meirhaeghe A, Cottel D, Amouyel P, Dallongeville J. Association between peroxisome proliferator-activated receptor gamma haplotypes and the metabolic syndrome in French men and women. Diabetes. 2005;54:3043-8 pubmed..In conclusion, a specific haplotype of PPARgamma polymorphisms is associated with an increased risk of the metabolic syndrome in a French general population. ..
- Meirhaeghe A, Boreham C, Murray L, Richard F, Davey Smith G, Young I, et al. A possible role for the PPARG Pro12Ala polymorphism in preterm birth. Diabetes. 2007;56:494-8 pubmed..In conclusion, the PPARG Pro12Ala polymorphism might represent a genetic susceptibility factor for preterm birth and constitute a link between preterm birth and metabolic diseases later in life. ..
- Meirhaeghe A, Sandhu M, McCarthy M, de Groote P, Cottel D, Arveiler D, et al. Association between the T-381C polymorphism of the brain natriuretic peptide gene and risk of type 2 diabetes in human populations. Hum Mol Genet. 2007;16:1343-50 pubmed..015, n = 634) and higher BNP promoter activity in reporter gene assays. Collectively, these data suggest that relatively high BNP expression may protect against type 2 diabetes in humans. ..