Florence Lerebours

Summary

Affiliation: Institut Curie
Country: France

Publications

  1. doi request reprint miRNA expression profiling of inflammatory breast cancer identifies a 5-miRNA signature predictive of breast tumor aggressiveness
    Florence Lerebours
    Laboratoire d oncogénétique, Institut Curie, Hôpital René Huguenin, 35 rue Dailly, Saint Cloud, France
    Int J Cancer 133:1614-23. 2013
  2. pmc Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy
    Ivan Bieche
    INSERM U735, Institut Curie Hôpital René Huguenin, St Cloud, France
    Mol Cancer 10:23. 2011
  3. pmc NF-kappa B genes have a major role in inflammatory breast cancer
    Florence Lerebours
    Centre Rene Huguenin, FNCLCC, 35 rue Dailly, 92210, St Cloud, France
    BMC Cancer 8:41. 2008
  4. doi request reprint ¹⁸F-FDG PET/CT imaging versus dynamic contrast-enhanced CT for staging and prognosis of inflammatory breast cancer
    Laurence Champion
    Service de Medecine Nucleaire, Saint Cloud, France
    Eur J Nucl Med Mol Imaging 40:1206-13. 2013
  5. doi request reprint Radiotherapy for stage II and stage III breast cancer patients with negative lymph nodes after preoperative chemotherapy and mastectomy
    Romuald Le Scodan
    Department of Radiation Oncology, Institut Curie Hôpital René Huguenin, Saint Cloud, France
    Int J Radiat Oncol Biol Phys 82:e1-7. 2012
  6. doi request reprint Brain metastases from breast cancer: proposition of new prognostic score including molecular subtypes and treatment
    Romuald Le Scodan
    Department of Radiation Oncology, Institut Curie Hôpital René Huguenin, 35 rue Dailly, 92210 Saint Cloud, France
    J Neurooncol 106:169-76. 2012
  7. pmc Identification of new candidate therapeutic target genes in triple-negative breast cancer
    Mathilde Glénisson
    Laboratory of Oncogenetic, Institut Curie, Hôpital René Huguenin, St Cloud, France
    Genes Cancer 3:63-70. 2012
  8. doi request reprint 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) imaging in the staging and prognosis of inflammatory breast cancer
    Jean Louis Alberini
    Nuclear Medicine Department, Cancer Research Center Rene Huguenin, Saint Cloud, France
    Cancer 115:5038-47. 2009
  9. doi request reprint Assessment of response to endocrine therapy using FDG PET/CT in metastatic breast cancer: a pilot study
    Nina Mortazavi-Jehanno
    Service de Medecine Nucleaire, Institut Curie, Hôpital René Huguenin, Saint Cloud, France
    Eur J Nucl Med Mol Imaging 39:450-60. 2012
  10. pmc Non-sentinel lymph node metastasis prediction in breast cancer with metastatic sentinel lymph node: impact of molecular subtypes classification
    Fabien Reyal
    Department of Surgery, Institut Curie, Paris, France
    PLoS ONE 7:e47390. 2012

Detail Information

Publications15

  1. doi request reprint miRNA expression profiling of inflammatory breast cancer identifies a 5-miRNA signature predictive of breast tumor aggressiveness
    Florence Lerebours
    Laboratoire d oncogénétique, Institut Curie, Hôpital René Huguenin, 35 rue Dailly, Saint Cloud, France
    Int J Cancer 133:1614-23. 2013
    ..Moreover, multivariate analysis showed that this signature was an independent predictor of poor Metastasis-Free Survival in non-IBC patients. ..
  2. pmc Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy
    Ivan Bieche
    INSERM U735, Institut Curie Hôpital René Huguenin, St Cloud, France
    Mol Cancer 10:23. 2011
    ..Alterations of the mitotic spindle checkpoint are likely to contribute to these phenotypes, but little is known about somatic alterations of mitotic spindle checkpoint genes in breast cancer...
  3. pmc NF-kappa B genes have a major role in inflammatory breast cancer
    Florence Lerebours
    Centre Rene Huguenin, FNCLCC, 35 rue Dailly, 92210, St Cloud, France
    BMC Cancer 8:41. 2008
    ..Given the role of NF-kappaB-related genes in cell proliferation, invasiveness, angiogenesis and inflammation, we postulated that they might be deregulated in IBC...
  4. doi request reprint ¹⁸F-FDG PET/CT imaging versus dynamic contrast-enhanced CT for staging and prognosis of inflammatory breast cancer
    Laurence Champion
    Service de Medecine Nucleaire, Saint Cloud, France
    Eur J Nucl Med Mol Imaging 40:1206-13. 2013
    ..Locoregional staging is based on dynamic contrast-enhanced (DCE) CT or MRI. The aim of this study was to compare the performances of FDG PET/CT and DCE CT in locoregional staging of IBC and to assess their respective prognostic values...
  5. doi request reprint Radiotherapy for stage II and stage III breast cancer patients with negative lymph nodes after preoperative chemotherapy and mastectomy
    Romuald Le Scodan
    Department of Radiation Oncology, Institut Curie Hôpital René Huguenin, Saint Cloud, France
    Int J Radiat Oncol Biol Phys 82:e1-7. 2012
    ..To evaluate the effect of postmastectomy radiotherapy (PMRT) in Stage II-III breast cancer patients with negative lymph nodes (pN0) after neoadjuvant chemotherapy (NAC)...
  6. doi request reprint Brain metastases from breast cancer: proposition of new prognostic score including molecular subtypes and treatment
    Romuald Le Scodan
    Department of Radiation Oncology, Institut Curie Hôpital René Huguenin, 35 rue Dailly, 92210 Saint Cloud, France
    J Neurooncol 106:169-76. 2012
    ..The other patients had a median survival of 12.5 months (P < 0.001). This 3-class specific prognostic score successfully predicted the outcomes of a heterogeneous group of patients with brain metastases from BC...
  7. pmc Identification of new candidate therapeutic target genes in triple-negative breast cancer
    Mathilde Glénisson
    Laboratory of Oncogenetic, Institut Curie, Hôpital René Huguenin, St Cloud, France
    Genes Cancer 3:63-70. 2012
    ..Clinical trials could be initiated easily with existing drugs. Our results also suggest that these target genes might serve as predictive biomarkers of the TNBC treatment response...
  8. doi request reprint 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) imaging in the staging and prognosis of inflammatory breast cancer
    Jean Louis Alberini
    Nuclear Medicine Department, Cancer Research Center Rene Huguenin, Saint Cloud, France
    Cancer 115:5038-47. 2009
    ..To prospectively assess fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) staging and prognosis value in patients with suspected inflammatory breast cancer (IBC)...
  9. doi request reprint Assessment of response to endocrine therapy using FDG PET/CT in metastatic breast cancer: a pilot study
    Nina Mortazavi-Jehanno
    Service de Medecine Nucleaire, Institut Curie, Hôpital René Huguenin, Saint Cloud, France
    Eur J Nucl Med Mol Imaging 39:450-60. 2012
    ..The purpose of this pilot study was to assess whether outcome in metastatic or recurrent breast cancer patients is related to metabolic response to endocrine therapy determined by (18)F-FDG PET/CT...
  10. pmc Non-sentinel lymph node metastasis prediction in breast cancer with metastatic sentinel lymph node: impact of molecular subtypes classification
    Fabien Reyal
    Department of Surgery, Institut Curie, Paris, France
    PLoS ONE 7:e47390. 2012
    ....
  11. doi request reprint Breast cancer with synchronous metastases: survival impact of exclusive locoregional radiotherapy
    Romuald Le Scodan
    Department of Radiation Oncology, Centre Rene Huguenin, 35 rue Dailly, 92210, Saint Cloud, France
    J Clin Oncol 27:1375-81. 2009
    ..Exclusive locoregional radiotherapy (LRR) is an alternative form of locoregional treatment (LRT) in this setting. We retrospectively studied the impact of LRT on the survival of breast cancer patients with synchronous metastases...
  12. pmc Time-Dependent Prognostic Impact of Circulating Tumor Cells Detection in Non-Metastatic Breast Cancer: 70-Month Analysis of the REMAGUS02 Study
    François Clément Bidard
    Department of Medical Oncology, Institut Curie, 26 Rue d Ulm, 75005 Paris, France Laboratory of Circulating Cancer Biomarker, Institut Curie, 26 Rue d Ulm, 75005 Paris, France
    Int J Breast Cancer 2013:130470. 2013
    ..We confirm that the detection of CTC is independently associated with a significantly worse outcome, but mainly during the first 3-4 years of follow-up. No prognostic impact is seen in patients who are still relapse-free at this moment...
  13. doi request reprint Immunomarker studies of fine-needle cytopuncture cell blocks for tumor response prediction after preoperative chemotherapy and prognosis in operable nonmetastatic primary breast carcinoma
    Veronique Becette
    Departments of Pathology Medical Oncology Oncogenetics, Institut Curie Hôpital René Huguenin, Saint Cloud, France
    Breast J 17:121-8. 2011
    ....
  14. ncbi request reprint Two prognostic groups of inflammatory breast cancer have distinct genotypes
    Florence Lerebours
    Institut National de la Santé et de la Recherche Médicale INSERM E0017 Oncogénétique, Centre Rene Huguenin, 35 rue Dailly, F 92211 St Cloud, France
    Clin Cancer Res 9:4184-9. 2003
    ..Analysis of loss of heterozygosity (LOH) can provide a molecular portrait of the genetic alterations underlying stepwise cancer progression. We tested the value of LOH patterns as diagnostic and prognostic markers in IBC...
  15. doi request reprint Neoadjuvant bevacizumab, trastuzumab, and chemotherapy for primary inflammatory HER2-positive breast cancer (BEVERLY-2): an open-label, single-arm phase 2 study
    Jean Yves Pierga
    Institut Curie, Paris, France
    Lancet Oncol 13:375-84. 2012
    ..In our phase 2 trial, we aimed to assess efficacy and safety of neoadjuvant bevacizumab combined with trastuzumab and chemotherapy in patients with primary HER2-positive inflammatory breast cancer...