Ronan Le Goffic

Summary

Affiliation: Institut National de la Recherche Agronomique
Country: France

Publications

  1. doi Infection with influenza virus induces IL-33 in murine lungs
    Ronan Le Goffic
    Unite de Virologie et Immunologie Moleculaires, Unite de Recherche, Institut National de la Recherche Agronomique, Jouy en Josas, France
    Am J Respir Cell Mol Biol 45:1125-32. 2011
  2. pmc Kinetic characterization of PB1-F2-mediated immunopathology during highly pathogenic avian H5N1 influenza virus infection
    Olivier Leymarie
    Unite de Virologie et Immunologie Moleculaires, UR 892 INRA, Domaine de Vilvert, Jouy en Josas, France
    PLoS ONE 8:e57894. 2013
  3. doi Influenza A virus protein PB1-F2 exacerbates IFN-beta expression of human respiratory epithelial cells
    Ronan Le Goffic
    Unite de Virologie et Immunologie Moleculaires, Unité de Recherche 892 Institut National de la Recherche Agronomique, Domaine de Vilvert, Jouy en Josas, France
    J Immunol 185:4812-23. 2010
  4. pmc Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein
    Ronan Le Goffic
    Unite de Virologie et Immunologie Moleculaires, UR 892 INRA, Jouy en Josas, France
    PLoS Pathog 7:e1002202. 2011
  5. pmc PB1-F2 influenza A virus protein adopts a beta-sheet conformation and forms amyloid fibers in membrane environments
    Christophe Chevalier
    Institut National de la Recherche Agronomique, Unite de Virologie et Immunologie Moleculaires, UR892, Domaine de Vilvert, F 78350 Centre de Jouy en Josas, France
    J Biol Chem 285:13233-43. 2010
  6. pmc PB1-F2 Attenuates Virulence of Highly Pathogenic Avian H5N1 Influenza Virus in Chickens
    Olivier Leymarie
    Unite de Virologie et Immunologie Moleculaires, Unité de Recherche UR892, Institut National de la Recherche Agronomique, Jouy en Josas, France
    PLoS ONE 9:e100679. 2014
  7. pmc Identification of one novel candidate probiotic Lactobacillus plantarum strain active against influenza virus infection in mice by a large-scale screening
    Noura Kechaou
    INCommensal and Probiotics Host Interactions Laboratory, Micalis, Jouy en Josas, France
    Appl Environ Microbiol 79:1491-9. 2013

Collaborators

  • Hana M Weingartl
  • Yohannes Berhane
  • Luis G Bermúdez-Humarán
  • Human Rezaei
  • Jean Francois Chich
  • Christophe Chevalier
  • Olivier Leymarie
  • Bruno Da Costa
  • Bernard Delmas
  • Noura Kechaou
  • Luc Jouneau
  • Carissa Embury-Hyatt
  • Marco Moroldo
  • Valérie Lorin
  • Gregory Jouvion
  • Nicolas Escriou
  • Jean Marc Chatel
  • Stéphanie Courau
  • Jean Jacques Gratadoux
  • Philippe Langella
  • Pascal Molimard
  • Jérome Lecardonnel
  • Sébastien Blugeon
  • Nicolas Bertho
  • Pierre Louis Hervé
  • Florian Chain
  • Jasmina Vidic
  • Ali Al Bazzal
  • Jean François Vautherot
  • Vincent Février
  • Julie Bernard
  • Sylvie Noinville
  • Mohammed Moudjou
  • Christiane Bourdieu
  • Edwige Bouguyon

Detail Information

Publications7

  1. doi Infection with influenza virus induces IL-33 in murine lungs
    Ronan Le Goffic
    Unite de Virologie et Immunologie Moleculaires, Unite de Recherche, Institut National de la Recherche Agronomique, Jouy en Josas, France
    Am J Respir Cell Mol Biol 45:1125-32. 2011
    ..In conclusion, our findings evidenced a profound expression of IL-33 in lungs during both in vivo and in vitro IAV infections, suggesting a role for IL-33 in virus-induced lung infections...
  2. pmc Kinetic characterization of PB1-F2-mediated immunopathology during highly pathogenic avian H5N1 influenza virus infection
    Olivier Leymarie
    Unite de Virologie et Immunologie Moleculaires, UR 892 INRA, Domaine de Vilvert, Jouy en Josas, France
    PLoS ONE 8:e57894. 2013
    ....
  3. doi Influenza A virus protein PB1-F2 exacerbates IFN-beta expression of human respiratory epithelial cells
    Ronan Le Goffic
    Unite de Virologie et Immunologie Moleculaires, Unité de Recherche 892 Institut National de la Recherche Agronomique, Domaine de Vilvert, Jouy en Josas, France
    J Immunol 185:4812-23. 2010
    ....
  4. pmc Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein
    Ronan Le Goffic
    Unite de Virologie et Immunologie Moleculaires, UR 892 INRA, Jouy en Josas, France
    PLoS Pathog 7:e1002202. 2011
    ..Collectively, these data demonstrate that PB1-F2 strongly influences the early host response during IAV infection and provides new insights into the mechanisms by which PB1-F2 mediates virulence...
  5. pmc PB1-F2 influenza A virus protein adopts a beta-sheet conformation and forms amyloid fibers in membrane environments
    Christophe Chevalier
    Institut National de la Recherche Agronomique, Unite de Virologie et Immunologie Moleculaires, UR892, Domaine de Vilvert, F 78350 Centre de Jouy en Josas, France
    J Biol Chem 285:13233-43. 2010
    ..All of these observations suggest that PB1-F2 could be involved in physiological processes through different pathways, permeabilization of cellular membranes, and amyloid fiber formation...
  6. pmc PB1-F2 Attenuates Virulence of Highly Pathogenic Avian H5N1 Influenza Virus in Chickens
    Olivier Leymarie
    Unite de Virologie et Immunologie Moleculaires, Unité de Recherche UR892, Institut National de la Recherche Agronomique, Jouy en Josas, France
    PLoS ONE 9:e100679. 2014
    ..In summary, our data suggest that PB1-F2 expression deeply affect the immune response in chickens in a way that may attenuate pathogenicity at low infection dose, a feature differing from what was previously observed in mammal species. ..
  7. pmc Identification of one novel candidate probiotic Lactobacillus plantarum strain active against influenza virus infection in mice by a large-scale screening
    Noura Kechaou
    INCommensal and Probiotics Host Interactions Laboratory, Micalis, Jouy en Josas, France
    Appl Environ Microbiol 79:1491-9. 2013
    ..Moreover, we identified a novel candidate probiotic strain, L. plantarum CNRZ1997, active against influenza virus infection in mice...