Ronan Le Goffic

Summary

Affiliation: Institut National de la Recherche Agronomique
Country: France

Publications

  1. ncbi Infection with influenza virus induces IL-33 in murine lungs
    Ronan Le Goffic
    Unite de Virologie et Immunologie Moleculaires, Unite de Recherche, Institut National de la Recherche Agronomique, Jouy en Josas, France
    Am J Respir Cell Mol Biol 45:1125-32. 2011
  2. ncbi Influenza A virus protein PB1-F2 exacerbates IFN-beta expression of human respiratory epithelial cells
    Ronan Le Goffic
    Unite de Virologie et Immunologie Moleculaires, Unité de Recherche 892 Institut National de la Recherche Agronomique, Domaine de Vilvert, Jouy en Josas, France
    J Immunol 185:4812-23. 2010
  3. ncbi Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein
    Ronan Le Goffic
    Unite de Virologie et Immunologie Moleculaires, UR 892 INRA, Jouy en Josas, France
    PLoS Pathog 7:e1002202. 2011
  4. ncbi PB1-F2 influenza A virus protein adopts a beta-sheet conformation and forms amyloid fibers in membrane environments
    Christophe Chevalier
    Institut National de la Recherche Agronomique, Unite de Virologie et Immunologie Moleculaires, UR892, Domaine de Vilvert, F 78350 Centre de Jouy en Josas, France
    J Biol Chem 285:13233-43. 2010

Collaborators

  • Human Rezaei
  • Jean Francois Chich
  • Christophe Chevalier
  • Sylvie Noinville
  • Mohammed Moudjou
  • Jean François Vautherot
  • Edwige Bouguyon
  • Vincent Février
  • Ali Al Bazzal
  • Jasmina Vidic
  • Christiane Bourdieu
  • Bruno Da Costa
  • Julie Bernard
  • Bernard Delmas

Detail Information

Publications4

  1. ncbi Infection with influenza virus induces IL-33 in murine lungs
    Ronan Le Goffic
    Unite de Virologie et Immunologie Moleculaires, Unite de Recherche, Institut National de la Recherche Agronomique, Jouy en Josas, France
    Am J Respir Cell Mol Biol 45:1125-32. 2011
    ..In conclusion, our findings evidenced a profound expression of IL-33 in lungs during both in vivo and in vitro IAV infections, suggesting a role for IL-33 in virus-induced lung infections...
  2. ncbi Influenza A virus protein PB1-F2 exacerbates IFN-beta expression of human respiratory epithelial cells
    Ronan Le Goffic
    Unite de Virologie et Immunologie Moleculaires, Unité de Recherche 892 Institut National de la Recherche Agronomique, Domaine de Vilvert, Jouy en Josas, France
    J Immunol 185:4812-23. 2010
    ....
  3. ncbi Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein
    Ronan Le Goffic
    Unite de Virologie et Immunologie Moleculaires, UR 892 INRA, Jouy en Josas, France
    PLoS Pathog 7:e1002202. 2011
    ..Collectively, these data demonstrate that PB1-F2 strongly influences the early host response during IAV infection and provides new insights into the mechanisms by which PB1-F2 mediates virulence...
  4. ncbi PB1-F2 influenza A virus protein adopts a beta-sheet conformation and forms amyloid fibers in membrane environments
    Christophe Chevalier
    Institut National de la Recherche Agronomique, Unite de Virologie et Immunologie Moleculaires, UR892, Domaine de Vilvert, F 78350 Centre de Jouy en Josas, France
    J Biol Chem 285:13233-43. 2010
    ..All of these observations suggest that PB1-F2 could be involved in physiological processes through different pathways, permeabilization of cellular membranes, and amyloid fiber formation...