Cécile Le Péchoux

Summary

Affiliation: Institut Gustave Roussy
Country: France

Publications

  1. doi request reprint Should adjuvant radiotherapy be administered in addition to front-line aggressive surgery (FAS) in patients with primary retroperitoneal sarcoma?
    C Le Pechoux
    Department of Radiation Oncology, Institut Gustave Roussy, Villejuif 94800, France
    Ann Oncol 24:832-7. 2013
  2. doi request reprint [Present role of prophylactic cranial irradiation]
    Cécile Le Péchoux
    Institut Gustave Roussy, Departement de Radiotherapie, 114, rue Edouard Vaillant, 94805 Villejuif, France
    Bull Cancer 100:35-43. 2013
  3. doi request reprint Standard-dose versus higher-dose prophylactic cranial irradiation (PCI) in patients with limited-stage small-cell lung cancer in complete remission after chemotherapy and thoracic radiotherapy (PCI 99-01, EORTC 22003-08004, RTOG 0212, and IFCT 99-01): a r
    Cécile Le Péchoux
    Radiotherapy Department, Institut Gustave Roussy, Villejuif, France
    Lancet Oncol 10:467-74. 2009
  4. ncbi request reprint [Small cell lung cancer (CPC). Management of patients presenting with limited stage small cell carcinoma of the lung]
    C Le Pechoux
    Departement de Radiotherapie, Institut Gustave Roussy, Villejuif, France
    Rev Mal Respir 23:16S188-16S197. 2006
  5. pmc Role of postoperative radiotherapy in resected non-small cell lung cancer: a reassessment based on new data
    Cécile Le Péchoux
    Institut Gustave Roussy, Radiotherapy Department, Villejuif 94800, France
    Oncologist 16:672-81. 2011
  6. ncbi request reprint [Place and technical aspects of external beam radiation therapy in the treatment of adult soft tissue sarcomas]
    Cécile Le Péchoux
    Departement de Radiotherapie, Institut Gustave Roussy, 94805 Villejuif, France
    Cancer Radiother 10:50-62. 2006
  7. ncbi request reprint [Thoracic adenoid cystic carcinomas]
    C Le Pechoux
    Service de Radiotherapie, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94000Villejuif, France
    Cancer Radiother 9:358-61. 2005
  8. ncbi request reprint [Thymic tumors]
    C Le Pechoux
    Departement de Radiotherapie, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94000 Villejuif, France
    Cancer Radiother 9:351-7. 2005
  9. pmc Clinical neurological outcome and quality of life among patients with limited small-cell cancer treated with two different doses of prophylactic cranial irradiation in the intergroup phase III trial (PCI99-01, EORTC 22003-08004, RTOG 0212 and IFCT 99-01)
    C Le Pechoux
    Radiation Oncology Department, Institut Gustave Roussy, Villejuif, France
    Ann Oncol 22:1154-63. 2011
  10. ncbi request reprint [Modalities of radiotherapy in small cell lung cancer: thoracic radiotherapy and prophylactic cerebral irradiation]
    C Le Pechoux
    Departement de Radiotherapie, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif
    Rev Pneumol Clin 60:3S91-103. 2004

Detail Information

Publications31

  1. doi request reprint Should adjuvant radiotherapy be administered in addition to front-line aggressive surgery (FAS) in patients with primary retroperitoneal sarcoma?
    C Le Pechoux
    Department of Radiation Oncology, Institut Gustave Roussy, Villejuif 94800, France
    Ann Oncol 24:832-7. 2013
    ..The aim of this study was to evaluate conformal postoperative radiotherapy (PORT) in patients who had enlarged surgery...
  2. doi request reprint [Present role of prophylactic cranial irradiation]
    Cécile Le Péchoux
    Institut Gustave Roussy, Departement de Radiotherapie, 114, rue Edouard Vaillant, 94805 Villejuif, France
    Bull Cancer 100:35-43. 2013
    ..Among long-term survivors, neuro-cognitive toxicity may be observed. Several approaches are being evaluated to reduce this possible toxicity. PCI has no place for other solid tumours at risk such as HER2+ breast cancer patients...
  3. doi request reprint Standard-dose versus higher-dose prophylactic cranial irradiation (PCI) in patients with limited-stage small-cell lung cancer in complete remission after chemotherapy and thoracic radiotherapy (PCI 99-01, EORTC 22003-08004, RTOG 0212, and IFCT 99-01): a r
    Cécile Le Péchoux
    Radiotherapy Department, Institut Gustave Roussy, Villejuif, France
    Lancet Oncol 10:467-74. 2009
    ..A meta-analysis suggested that the incidence of brain metastases might be reduced with higher PCI doses. This randomised clinical trial compared the effect of standard versus higher PCI doses on the incidence of brain metastases...
  4. ncbi request reprint [Small cell lung cancer (CPC). Management of patients presenting with limited stage small cell carcinoma of the lung]
    C Le Pechoux
    Departement de Radiotherapie, Institut Gustave Roussy, Villejuif, France
    Rev Mal Respir 23:16S188-16S197. 2006
    ..In addition the potential role of targeted therapy in selected patients must be examined...
  5. pmc Role of postoperative radiotherapy in resected non-small cell lung cancer: a reassessment based on new data
    Cécile Le Péchoux
    Institut Gustave Roussy, Radiotherapy Department, Villejuif 94800, France
    Oncologist 16:672-81. 2011
    ..A new large multi-institutional randomized trial evaluating PORT in this patient population is needed and now under way...
  6. ncbi request reprint [Place and technical aspects of external beam radiation therapy in the treatment of adult soft tissue sarcomas]
    Cécile Le Péchoux
    Departement de Radiotherapie, Institut Gustave Roussy, 94805 Villejuif, France
    Cancer Radiother 10:50-62. 2006
    ..A randomized trial is warranted. Because of its rarity, and the risk of recurrence both local and metastatic, treatment should preferentially be discussed with a multimodality specialized approach...
  7. ncbi request reprint [Thoracic adenoid cystic carcinomas]
    C Le Pechoux
    Service de Radiotherapie, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94000Villejuif, France
    Cancer Radiother 9:358-61. 2005
    ..Local or metastatic recurrences may occur very lately. They are considered chemo-resistant and targeted therapies may prove to be effective in the future...
  8. ncbi request reprint [Thymic tumors]
    C Le Pechoux
    Departement de Radiotherapie, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94000 Villejuif, France
    Cancer Radiother 9:351-7. 2005
    ..In inoperable locally advanced, or metastatic thymic tumors, neoadjuvant cisplatin-based followed by surgery and radiotherapy has given interesting results in the past years...
  9. pmc Clinical neurological outcome and quality of life among patients with limited small-cell cancer treated with two different doses of prophylactic cranial irradiation in the intergroup phase III trial (PCI99-01, EORTC 22003-08004, RTOG 0212 and IFCT 99-01)
    C Le Pechoux
    Radiation Oncology Department, Institut Gustave Roussy, Villejuif, France
    Ann Oncol 22:1154-63. 2011
    ..As concerns about neurotoxicity were a major issue surrounding PCI, we report here midterm and long-term repeated evaluation of neurocognitive functions and quality of life (QoL)...
  10. ncbi request reprint [Modalities of radiotherapy in small cell lung cancer: thoracic radiotherapy and prophylactic cerebral irradiation]
    C Le Pechoux
    Departement de Radiotherapie, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif
    Rev Pneumol Clin 60:3S91-103. 2004
    ....
  11. ncbi request reprint Prophylactic cranial irradiation in small cell lung cancer
    Cécile Le Péchoux
    Department of Radiotherapy, Institut Gustave Roussy, Villejuif 94805, France
    Hematol Oncol Clin North Am 18:355-72. 2004
  12. ncbi request reprint [Lung cancer: is there a place for elective nodal irradiation?]
    C Le Pechoux
    Departement de Radiotherapie, Institut Gustave Roussy, 39, rue Camille Desmoulins, Villejuif, France
    Cancer Radiother 10:354-60. 2006
    ..Further larger-scale studies would be needed to definitely establish "no elective nodal irradiation" as a standard in non-small cell lung cancer. There are very few data concerning small cell lung cancer...
  13. doi request reprint Follow-up of hepatic and peritoneal metastases of gastrointestinal tumors (GIST) under Imatinib therapy requires different criteria of radiological evaluation (size is not everything!!!)
    Mylene Mabille
    Department of Radiology, Institut Gustave Roussy, Villejuif, France
    Eur J Radiol 69:204-8. 2009
    ..To define computed tomography (CT) criteria for evaluating the response of patients with gastrointestinal stromal tumors (GIST) who are receiving Imatinib (tyrosine-kinase inhibitor therapy)...
  14. doi request reprint Epithelioid sarcoma: need for a multimodal approach to maximize the chances of curative conservative treatment
    Antonin Levy
    Department of Radiation Oncology, Institut Gustave Roussy, Universite Paris Sud, Villejuif, France
    Ann Surg Oncol 21:269-76. 2014
    ..This study was designed to evaluate the impact of multimodal management on a series of epithelioid sarcoma (ES) patients treated with curative intent...
  15. ncbi request reprint [Management of recurrent soft tissue sarcoma of the retroperitoneum]
    Sylvie Bonvalot
    Departement de Chirurgie, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif
    Bull Cancer 91:845-52. 2004
    ..Adequate management at the time of primary presentation is likely to afford the best chance for long-term survival...
  16. doi request reprint Aggressive surgery in retroperitoneal soft tissue sarcoma carried out at high-volume centers is safe and is associated with improved local control
    Sylvie Bonvalot
    Department of Surgery, Institut Gustave Roussy, Villejuif, France
    Ann Surg Oncol 17:1507-14. 2010
    ..We sought to assess morbidity and mortality in primary retroperitoneal soft tissue sarcomas (RSTS) treated by a frontline aggressive surgical approach...
  17. doi request reprint Feasibility of metronomic oral cyclophosphamide plus prednisolone in elderly patients with inoperable or metastatic soft tissue sarcoma
    Olivier Mir
    Sarcoma Unit, Herault Ward, Department of Medicine, Institut Gustave Roussy, Université Paris 11, 39 rue Camille Desmoulins, Villejuif, France
    Eur J Cancer 47:515-9. 2011
    ..A sizeable population of elderly patients with STS is unfit for conventional doxorubicin- or ifosfamide-based chemotherapy. We assessed the feasibility of metronomic oral cyclophosphamide (CPM) in this population...
  18. doi request reprint Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer
    Anne Auperin
    Unit of Biostatistics and Epidemiology, Institut Gustave Roussy, 94805 Villejuif Cedex, France
    J Clin Oncol 28:2181-90. 2010
    ..The NSCLC Collaborative Group performed a meta-analysis of randomized trials directly comparing concomitant versus sequential radiochemotherapy...
  19. doi request reprint Radiotherapy in small-cell lung cancer: where should it go?
    Amaury Paumier
    Institut Gustave Roussy, Radiation Oncology Department, 39 rue Camille Desmoulins, Villejuif 94800, France
    Lung Cancer 69:133-40. 2010
    ..Progress in thoracic radiotherapy can only be achieved by including patients in prospective studies...
  20. ncbi request reprint Combined modality treatment of lung cancer (NSCLC and SCLC)
    Catherine Delbaldo
    Department of Medicine, Institut Gustave Roussy 39, rue Camille Desmoulins, 94800, Villejuif, France
    Cancer Chemother Biol Response Modif 20:677-95. 2002
  21. pmc Surrogate endpoints for overall survival in chemotherapy and radiotherapy trials in operable and locally advanced lung cancer: a re-analysis of meta-analyses of individual patients' data
    Audrey Mauguen
    Meta analysis Unit, Department of Biostatistics and Epidemiology, Gustave Roussy Institute, Villejuif, France
    Lancet Oncol 14:619-26. 2013
    ..Surrogate endpoints that would enable earlier assessments of treatment effects would be useful. We assessed the correlations between potential surrogate endpoints and overall survival at individual and trial levels...
  22. doi request reprint IMRT or conformal radiotherapy for adjuvant treatment of retroperitoneal sarcoma?
    Amaury Paumier
    Department of Radiation Oncology, Institut Gustave Roussy, Villejuif, France
    Radiother Oncol 99:73-8. 2011
    ....
  23. doi request reprint Hyperthermic isolated limb perfusion in locally advanced soft tissue sarcoma and progressive desmoid-type fibromatosis with TNF 1 mg and melphalan (T1-M HILP) is safe and efficient
    Sylvie Bonvalot
    Department of Surgery, Institut Gustave Roussy, Villejuif Cedex, France
    Ann Surg Oncol 16:3350-7. 2009
    ..The objective of the present study was to confirm these data on a larger sample size of locally advanced or recurrent extremity soft tissue sarcomas with low-dose TNF-alpha...
  24. doi request reprint Conservative en bloc surgery for aggressive angiomyxoma achieves good local control: analysis of 14 patients from a single institution
    Sarah Coppola
    Department of Surgery, Institut Gustave Roussy, Villejuif, France
    Int J Gynecol Cancer 23:540-5. 2013
    ..The purpose of this study was to assess the value of conservative surgery in aggressive angiomyxoma (AA) in our institutional series...
  25. ncbi request reprint Role of computed tomography in the follow-up of hepatic and peritoneal metastases of GIST under imatinib mesylate treatment: a prospective study of 54 patients
    Daniel Vanel
    Department of Radiology, Institut Gustave Roussy, rue Camille Desmoulins, 94800 Villejuif, France
    Eur J Radiol 54:118-23. 2005
    ..To prospectively analyze the evolution of hepatic and peritoneal unresectable metastases from gastrointestinal stromal tumors (GIST) under imatinib mesylate, a new targeted treatment, which induces changes in lesion structure...
  26. doi request reprint Respiratory gating techniques for optimization of lung cancer radiotherapy
    Philippe Giraud
    Department of Radiation Oncology, Paris Descartes University, Sorbonne Paris Cité, Hopital Europeen Georges Pompidou, Paris, France
    J Thorac Oncol 6:2058-68. 2011
    ....
  27. doi request reprint Hyperfractionated or accelerated radiotherapy in lung cancer: an individual patient data meta-analysis
    Audrey Mauguen
    Institut de Cance rologie Gustave Roussy, Villejuif, France
    J Clin Oncol 30:2788-97. 2012
    ..The Meta-Analysis of Radiotherapy in Lung Cancer Collaborative Group decided to address the role of modified radiotherapy fractionation...
  28. doi request reprint Long-term results of the international adjuvant lung cancer trial evaluating adjuvant Cisplatin-based chemotherapy in resected lung cancer
    Rodrigo Arriagada
    Institut Gustave Roussy, rue Camille Desmoulins, Villejuif 94800, France
    J Clin Oncol 28:35-42. 2010
    ....
  29. doi request reprint Prophylactic cranial irradiation in lung cancer
    Pierre Blanchard
    Radiation Oncology Department, Institut Gustave Roussy, Villejuif, France
    Curr Opin Oncol 22:94-101. 2010
    ..Prophylactic cranial irradiation (PCI) has been proposed in both small-cell lung cancers (SCLCs) and non-SCLCs to reduce the incidence of brain metastases and increase survival...
  30. doi request reprint Impact of (18)F-FDG PET on treatment strategy and 3D radiotherapy planning in non-small cell lung cancer: A prospective multicenter study
    Pascal Pommier
    Department of Radiation Oncology, Lyon University Centre Léon Bérard, France
    AJR Am J Roentgenol 195:350-5. 2010
    ....
  31. doi request reprint Small cell lung cancer: new clinical recommendations and current status of biomarker assessment
    David Planchard
    Medical Oncology Department, Institut Gustave Roussy, Villejuif, France
    Eur J Cancer 47:S272-83. 2011
    ..Pursuing clinical trials at all stages constitutes a challenge for thoracic researchers and oncologists...