Jean Paul Latge

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. doi request reprint Characterization of glucuronic acid containing glycolipid in Aspergillus fumigatus mycelium
    Thierry Fontaine
    Institut Pasteur, Paris, France
    Carbohydr Res 344:1960-7. 2009
  2. pmc Inducible expression of beta defensins by human respiratory epithelial cells exposed to Aspergillus fumigatus organisms
    Ludmila Alekseeva
    UMR 956, INRA, AFSSA, ENVA, Maisons Alfort Cedex, France
    BMC Microbiol 9:33. 2009
  3. pmc Aspergillus fumigatus and aspergillosis
    J P Latge
    Laboratoire des Aspergillus, Institut Pasteur, 75015 Paris, France
    Clin Microbiol Rev 12:310-50. 1999
  4. ncbi request reprint The cell wall: a carbohydrate armour for the fungal cell
    Jean Paul Latge
    Unite des Aspergillus, Institut Pasteur, 25, rue du Dr Roux, 75015 Paris, France
    Mol Microbiol 66:279-90. 2007
  5. doi request reprint Galactofuranose containing molecules in Aspergillus fumigatus
    Jean Paul Latge
    Aspergillus Unit, Institut Pasteur, Paris, France
    Med Mycol 47:S104-9. 2009
  6. pmc Global transcriptome changes underlying colony growth in the opportunistic human pathogen Aspergillus fumigatus
    John G Gibbons
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA
    Eukaryot Cell 11:68-78. 2012
  7. ncbi request reprint The pathobiology of Aspergillus fumigatus
    J P Latge
    Unite des Aspergillus, Institut Pasteur, 25 rue du Dr Roux, 75015, Paris, France
    Trends Microbiol 9:382-9. 2001
  8. ncbi request reprint Specific molecular features in the organization and biosynthesis of the cell wall of Aspergillus fumigatus
    J P Latge
    Unite des Aspergillus, Institut Pasteur, Paris, France
    Med Mycol 43:S15-22. 2005
  9. doi request reprint Members of protein O-mannosyltransferase family in Aspergillus fumigatus differentially affect growth, morphogenesis and viability
    Isabelle Mouyna
    Unite des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux 75724 Paris Cedex 15, France
    Mol Microbiol 76:1205-21. 2010
  10. pmc Involvement of toll-like receptor 2 in experimental invasive pulmonary aspergillosis
    Viviane Balloy
    Unité de Défense Innée et Inflammation, INSERM E336, Institut Pasteur, 25, rue du Dr Roux, 75015 Paris, France
    Infect Immun 73:5420-5. 2005

Collaborators

Detail Information

Publications59

  1. doi request reprint Characterization of glucuronic acid containing glycolipid in Aspergillus fumigatus mycelium
    Thierry Fontaine
    Institut Pasteur, Paris, France
    Carbohydr Res 344:1960-7. 2009
    ..Gene deletion showed that only UGD1 is essential for the biosynthesis of GlcA-DG. However, no particular phenotype has been observed in the Ugd1Delta mutant. Biological function of this acidic glycolipid remains unknown in A. fumigatus...
  2. pmc Inducible expression of beta defensins by human respiratory epithelial cells exposed to Aspergillus fumigatus organisms
    Ludmila Alekseeva
    UMR 956, INRA, AFSSA, ENVA, Maisons Alfort Cedex, France
    BMC Microbiol 9:33. 2009
    ..The role of the airway epithelium involves a complex interaction with the inhaled pathogen. Antimicrobial peptides with direct antifungal and chemotactic activities may boost antifungal immune response...
  3. pmc Aspergillus fumigatus and aspergillosis
    J P Latge
    Laboratoire des Aspergillus, Institut Pasteur, 75015 Paris, France
    Clin Microbiol Rev 12:310-50. 1999
    ....
  4. ncbi request reprint The cell wall: a carbohydrate armour for the fungal cell
    Jean Paul Latge
    Unite des Aspergillus, Institut Pasteur, 25, rue du Dr Roux, 75015 Paris, France
    Mol Microbiol 66:279-90. 2007
    ..To date, only beta1,3 glucan synthase inhibitors have been launched clinically and many more targets remain to be explored...
  5. doi request reprint Galactofuranose containing molecules in Aspergillus fumigatus
    Jean Paul Latge
    Aspergillus Unit, Institut Pasteur, Paris, France
    Med Mycol 47:S104-9. 2009
    ....
  6. pmc Global transcriptome changes underlying colony growth in the opportunistic human pathogen Aspergillus fumigatus
    John G Gibbons
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA
    Eukaryot Cell 11:68-78. 2012
    ..These results add valuable insight into the genetics of biofilm formation in A. fumigatus and other filamentous fungi and identify many relevant, in the context of biofilm biology, candidate genes for downstream functional experiments...
  7. ncbi request reprint The pathobiology of Aspergillus fumigatus
    J P Latge
    Unite des Aspergillus, Institut Pasteur, 25 rue du Dr Roux, 75015, Paris, France
    Trends Microbiol 9:382-9. 2001
    ..fumigatus have yet to be elucidated...
  8. ncbi request reprint Specific molecular features in the organization and biosynthesis of the cell wall of Aspergillus fumigatus
    J P Latge
    Unite des Aspergillus, Institut Pasteur, Paris, France
    Med Mycol 43:S15-22. 2005
    ..This chemo-genomic comparative analysis has also suggested that GPI-anchored proteins do not have a role of linker in the three dimensional organization of the fungal cell wall...
  9. doi request reprint Members of protein O-mannosyltransferase family in Aspergillus fumigatus differentially affect growth, morphogenesis and viability
    Isabelle Mouyna
    Unite des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux 75724 Paris Cedex 15, France
    Mol Microbiol 76:1205-21. 2010
    ..These results indicate that the PMT family members play a major role in growth, morphogenesis and viability of A. fumigatus...
  10. pmc Involvement of toll-like receptor 2 in experimental invasive pulmonary aspergillosis
    Viviane Balloy
    Unité de Défense Innée et Inflammation, INSERM E336, Institut Pasteur, 25, rue du Dr Roux, 75015 Paris, France
    Infect Immun 73:5420-5. 2005
    ..Infected TLR2(-/-) mice also have a higher respiratory distress and a higher pathogen burden than TLR2(+/+) mice. These data demonstrate that TLR2 plays a significant role in the defense of the host against A. fumigatus infection...
  11. pmc Glycosylphosphatidylinositol-anchored Ecm33p influences conidial cell wall biosynthesis in Aspergillus fumigatus
    Sandrine Chabane
    Aspergillus Unit, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Appl Environ Microbiol 72:3259-67. 2006
    ....
  12. pmc SUN proteins belong to a novel family of β-(1,3)-glucan-modifying enzymes involved in fungal morphogenesis
    Amandine Gastebois
    Institut Pasteur, Unite des Aspergillus, Département Parasitologie et Mycologie, 25 rue du Docteur Roux, F 75015 Paris
    J Biol Chem 288:13387-96. 2013
    ..SUN proteins are involved in yeast morphogenesis, but their function is unknown...
  13. pmc Characterization of a new beta(1-3)-glucan branching activity of Aspergillus fumigatus
    Amandine Gastebois
    Unite des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux, 75015 Paris, France
    J Biol Chem 285:2386-96. 2010
    ..fumigatus did not display any cell wall phenotype showing that these activities were not responsible for the construction of the branched beta(1-3)-glucans of the cell wall...
  14. doi request reprint Galactofuranose attenuates cellular adhesion of Aspergillus fumigatus
    Claude Lamarre
    Unite des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Cell Microbiol 11:1612-23. 2009
    ..Removal of the mannan layer from the mutant surface by a mannosidase treatment abolishes mycelial adhesion to surfaces...
  15. ncbi request reprint Deletion of GEL2 encoding for a beta(1-3)glucanosyltransferase affects morphogenesis and virulence in Aspergillus fumigatus
    Isabelle Mouyna
    Institut Pasteur, Unite des Aspergillus, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Mol Microbiol 56:1675-88. 2005
    ..These data suggest for the first time that beta(1-3)glucanosyltransferase activity is required for both morphogenesis and virulence in A. fumigatus...
  16. pmc Differences in patterns of infection and inflammation for corticosteroid treatment and chemotherapy in experimental invasive pulmonary aspergillosis
    Viviane Balloy
    Unité de Défense Innée et Inflammation, INSERM E336, Institut Pasteur, 25 rue du Dr Roux, 75015 Paris, France
    Infect Immun 73:494-503. 2005
    ..These previously unrecognized differences should be taken into account in evaluations of the pathogenesis of IPA in animal models...
  17. pmc Galactosaminogalactan, a new immunosuppressive polysaccharide of Aspergillus fumigatus
    Thierry Fontaine
    Unite des Aspergillus, Institut Pasteur, Paris, France
    PLoS Pathog 7:e1002372. 2011
    ..Most importantly, the polysaccharide promotes fungal development in immunocompetent mice due to its immunosuppressive activity associated with disminished neutrophil infiltrates...
  18. pmc beta(1-3)Glucanosyltransferase Gel4p is essential for Aspergillus fumigatus
    Amandine Gastebois
    Unite des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Eukaryot Cell 9:1294-8. 2010
    ..Like the other Gelps, it encodes a glycosylphosphatidylinositol (GPI)-anchored protein. In contrast to the other beta(1-3)glucanosyltransferases analyzed to date, it is essential for this fungal species...
  19. doi request reprint Comparative functional analysis of the OCH1 mannosyltransferase families in Aspergillus fumigatus and Saccharomyces cerevisiae
    Karine Lambou
    Unite des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Yeast 27:625-36. 2010
    ..Among the four orthologues, only AfOCH1 complemented the aggregation phenotype, the growth inhibition, the hypersensitivity to hygromycin and the protein glycosylation defects observed in the Scoch1Deltamutant...
  20. pmc A novel family of dehydrin-like proteins is involved in stress response in the human fungal pathogen Aspergillus fumigatus
    Joanne Wong Sak Hoi
    Unite des Aspergillus, Institut Pasteur, 75015 Paris, France
    Mol Biol Cell 22:1896-906. 2011
    ..Accordingly, DprA and DprB were important for peroxisome function. Our findings reveal a novel family of stress-protective proteins in A. fumigatus and, potentially, in filamentous ascomycetes...
  21. pmc Characterization of essential genes by parasexual genetics in the human fungal pathogen Aspergillus fumigatus: impact of genomic rearrangements associated with electroporation of DNA
    Arnaud Firon
    Unité Microbiologie et Environnement, CNRS URA 2172, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Genetics 161:1077-87. 2002
    ..fumigatus insertional mutants has relatively limited value and cannot be used in an exhaustive search of essential genes...
  22. pmc α1,3 glucans are dispensable in Aspergillus fumigatus
    Christine Henry
    Unite des Aspergillus, Institut Pasteur, Paris, France
    Eukaryot Cell 11:26-9. 2012
    ..The lack of α1,3 glucans affects neither conidial germination nor mycelial vegetative growth and is compensated by an increase in β1,3 glucan and/or chitin content...
  23. doi request reprint Cell wall alpha1-3glucans induce the aggregation of germinating conidia of Aspergillus fumigatus
    Thierry Fontaine
    Unite des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Fungal Genet Biol 47:707-12. 2010
    ....
  24. doi request reprint In vivo biofilm composition of Aspergillus fumigatus
    Celine Loussert
    Electron Microscopy Platform, Institut Pasteur, Paris, France
    Cell Microbiol 12:405-10. 2010
    ..A new galactosaminogalactan and the galactomannan were the major polysaccharides of the in vivo ECM. The composition of the ECM in vivo varied with the aspergillosis pathologies...
  25. ncbi request reprint Aspergillus fumigatus induces innate immune responses in alveolar macrophages through the MAPK pathway independently of TLR2 and TLR4
    Marc Dubourdeau
    Unite des Aspergillus, Institut National de la Santé et de la Recherche Médicale E336, Institut Pasteur, Paris, France
    J Immunol 177:3994-4001. 2006
    ..fumigatus under immunocompetent situations. Furthermore, our data stress the important role of ERK activation in innate immunity to A. fumigatus...
  26. ncbi request reprint Glycosylphosphatidylinositol-anchored fungal polysaccharide in Aspergillus fumigatus
    Corina Costachel
    Unite des Aspergillus, Institut Pasteur, 75724 Paris Cedex 15, France
    J Biol Chem 280:39835-42. 2005
    ..The GPI structure is a type 1, closely related to the one previously described for the GPI-anchored proteins of A. fumigatus. This is the first time that a fungal polysaccharide is shown to be GPI-anchored...
  27. pmc Catalases of Aspergillus fumigatus
    Sophie Paris
    Unite des Aspergillus, Département Structure et Dynamique des Génomes, Institut Pasteur, Paris, France
    Infect Immun 71:3551-62. 2003
    ..These results indicate that conidial catalase is not a virulence factor and that mycelial catalases transiently protect the fungus from the host...
  28. ncbi request reprint Gene silencing with RNA interference in the human pathogenic fungus Aspergillus fumigatus
    Isabelle Mouyna
    Institut Pasteur, Unite des Aspergillus, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    FEMS Microbiol Lett 237:317-24. 2004
    ..Use of RNA interference in Aspergillus will allow easier examination of the phenotypic consequences of reducing expression of a gene of interest, especially for essential genes...
  29. ncbi request reprint Characterization of the SKN7 ortholog of Aspergillus fumigatus
    Claude Lamarre
    Unite des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux, 75724 Cedex 15, France
    Fungal Genet Biol 44:682-90. 2007
    ..This result indicated that an increased sensitivity of A. fumigatus to peroxides in vitro is not correlated with a modification of fungal virulence...
  30. pmc Circulating human basophils lack the features of professional antigen presenting cells
    Meenu Sharma
    Unite 872, Institut National de la Sante et de la Recherche Medicale, Paris, F 75006, France
    Sci Rep 3:1188. 2013
    ..Together, these results demonstrate the inability of circulating human basophils to function as professional APC...
  31. pmc Phylogenetic and functional analysis of Aspergillus fumigatus MGTC, a fungal protein homologous to a bacterial virulence factor
    Amandine Gastebois
    Unite des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux, 75015 Paris, France
    Appl Environ Microbiol 77:4700-3. 2011
    ..Among eukaryotes, a gene homologous to mgtC was found only in the pathogenic fungus Aspergillus fumigatus. Our data show that the A. fumigatus MgtC (AfuMgtC) protein does not have the same function as the bacterial MgtC proteins...
  32. pmc Cell wall beta-(1,6)-glucan of Saccharomyces cerevisiae: structural characterization and in situ synthesis
    Vishukumar Aimanianda
    Unite des Aspergillus, CNRS URA 2185, Institut Pasteur, 25 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France
    J Biol Chem 284:13401-12. 2009
    ..cerevisiae yeasts resulted in the synthesis of a polymer chemically identical to the branched beta-(1,6)-glucan isolated from the cell wall. Using this assay, parameters essential for beta-(1,6)-glucan synthetic activity were defined...
  33. doi request reprint Functional analysis of the superoxide dismutase family in Aspergillus fumigatus
    Karine Lambou
    Unite des Aspergillus, Institut Pasteur, 25, rue du Docteur Roux, 75724 Paris Cedex 15, France
    Mol Microbiol 75:910-23. 2010
    ..In spite of these phenotypes, no significant virulence difference was observed between the triple mutant and parental strain in experimental murine aspergillosis models in immunocompromised animals...
  34. ncbi request reprint Structures of the glycosylphosphatidylinositol membrane anchors from Aspergillus fumigatus membrane proteins
    Thierry Fontaine
    Unite des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Glycobiology 13:169-77. 2003
    ..cerevisiae that contains diacylglycerol. The A. fumigatus GPI glycan moiety is mainly a linear pentomannose structure linked to a glucosamine residue: Manalpha1-3Manalpha1-2Manalpha1-2Manalpha1-6Manalpha1-4GlcN...
  35. pmc Characterization of the GPI-anchored endo β-1,3-glucanase Eng2 of Aspergillus fumigatus
    Lukas Hartl
    Unite des Aspergillus, Département de Parasitologie et Mycologie, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Fungal Genet Biol 48:185-91. 2011
    ..The growth phenotype of the Afeng2 mutant was identical to that of the wt strain...
  36. ncbi request reprint Characterization of a cell-wall acid phosphatase (PhoAp) in Aspergillus fumigatus
    Muriel Bernard
    Unite des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Microbiology 148:2819-29. 2002
    ..The absence of PhoAp from a phosphate-rich medium was not associated with a reduction in fungal growth, indicating that this cell-wall-associated protein does not play a role in the morphogenesis of A. fumigatus...
  37. ncbi request reprint Methylcitrate synthase from Aspergillus fumigatus is essential for manifestation of invasive aspergillosis
    Oumaima Ibrahim-Granet
    Aspergillus Unit, Institute Pasteur, 25 rue du Dr Roux, 75724 Paris Cedex 15, France
    Cell Microbiol 10:134-48. 2008
    ..fumigatus. Thus, blocking of methylcitrate synthase activity abrogates fungal growth and provides a suitable target for new antifungals...
  38. doi request reprint Characterization of a biofilm-like extracellular matrix in FLO1-expressing Saccharomyces cerevisiae cells
    Anne Beauvais
    Aspergillus Unit, Institut Pasteur, Paris, France
    FEMS Yeast Res 9:411-9. 2009
    ..Together, our results provide a new model system to study the formation and biological role of microbial extracellular matrices...
  39. doi request reprint Aspergillus fumigatus: cell wall polysaccharides, their biosynthesis and organization
    Amandine Gastebois
    Unite des Aspergillus, Institut Pasteur, 25 28 Rue du Docteur Roux, 75724, Paris, Cedex 15, France
    Future Microbiol 4:583-95. 2009
    ..fumigatus, it also discusses the antifungal drugs that affect cell wall polysaccharide biosynthesis...
  40. doi request reprint Tasting the fungal cell wall
    Jean Paul Latge
    Institut Pasteur, Unite des Aspergillus, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Cell Microbiol 12:863-72. 2010
    ..Eventhough progresses have been made in the last 10 years, a comprehensive understanding of the interactions between the host membrane receptors and the fungal cell wall components is still lacking...
  41. ncbi request reprint Aspergillus fumigatus: saprophyte or pathogen?
    Fredj Tekaia
    Unité de Génétique Moléculaire des Levures, URA 2171 CNRS and UFR 927, Universite Pierre et Marie Curie, Institut Pasteur, 25, rue du Dr Roux, 75015 Paris, France
    Curr Opin Microbiol 8:385-92. 2005
    ..fumigatus in an unfriendly environment such as its human host...
  42. ncbi request reprint An extracellular matrix glues together the aerial-grown hyphae of Aspergillus fumigatus
    Anne Beauvais
    Aspergillus Unit, Institut Pasteur, Paris, France
    Cell Microbiol 9:1588-600. 2007
    ..This is the first analysis of the three dimensional structure of a mycelial colony. Knowledge of this multicellular organization will impact our future understanding of the pathobiology of aerial mold pathogens...
  43. ncbi request reprint Testing the efficacy of RNA interference constructs in Aspergillus fumigatus
    Christine Henry
    Institut Pasteur, Unite des Aspergillus, 25 rue du Docteur Roux, 75724, Paris Cedex 15, France
    Curr Genet 51:277-84. 2007
    ..These disadvantages of RNAi indicate that classical gene disruption by gene replacement remains the most efficient method for a molecular analysis of gene function in A. fumigatus...
  44. pmc The composition of the culture medium influences the β-1,3-glucan metabolism of Aspergillus fumigatus and the antifungal activity of inhibitors of β-1,3-glucan synthesis
    Cecile Clavaud
    Unité des Aspergillus and Unité de Chimie et Biocatalyse, Institut Pasteur, Paris, France
    Antimicrob Agents Chemother 56:3428-31. 2012
    ....
  45. doi request reprint A novel dehydrin-like protein from Aspergillus fumigatus regulates freezing tolerance
    Joanne Wong Sak Hoi
    Unite des Aspergillus, Institut Pasteur, 25 rue du Dr Roux, 75015 Paris, France
    Fungal Genet Biol 49:210-6. 2012
    ..The DprC-mediated response was dependent on the SakA MAP kinase pathway, and accordingly, SakA phosphorylation was induced by cold shock. When fused to eGFP, the protein was associated with the vacuoles...
  46. pmc Transcriptomic analysis of the exit from dormancy of Aspergillus fumigatus conidia
    Claude Lamarre
    Unite des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    BMC Genomics 9:417. 2008
    ..fumigatus genome)...
  47. doi request reprint Surface hydrophobin prevents immune recognition of airborne fungal spores
    Vishukumar Aimanianda
    Unite des Aspergillus, Institut Pasteur, Paris F 75015, France
    Nature 460:1117-21. 2009
    ..All these observations show that the hydrophobic rodlet layer on the conidial cell surface immunologically silences airborne moulds...
  48. ncbi request reprint Recombinant antigens as diagnostic markers for aspergillosis
    Jacqueline Sarfati
    Unite des Aspergillus, Institut Pasteur, 75015 Paris, France
    Diagn Microbiol Infect Dis 55:279-91. 2006
    ..These results suggest that recombinant RNU, CAT, and DPPV have a great potential in the serodiagnosis of all forms of aspergillosis in the immunocompromised and immunocompetent patient...
  49. ncbi request reprint In vitro biosynthesis of glycosylphosphatidylinositol in Aspergillus fumigatus
    Thierry Fontaine
    Unite des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Biochemistry 43:15267-75. 2004
    ..Thus, these biochemical data are in agreement with a comparative genome analysis that shows that all but 3 of the 21 genes described in the Saccharomyces cerevisiae GPI pathways are found in A. fumigatus...
  50. ncbi request reprint Chitinases and peptide mimotopes
    Anne Beauvais
    Aspergillus Unit, Institut Pasteur, Paris, France
    Chem Biol 12:7-8. 2005
  51. pmc Pathway of glycine betaine biosynthesis in Aspergillus fumigatus
    Karine Lambou
    Unite des Aspergillus, Institut Pasteur, Paris, France
    Eukaryot Cell 12:853-63. 2013
    ..This study in A. fumigatus is the first molecular, cellular, and biochemical characterization of the glycine betaine biosynthetic pathway in the fungal kingdom...
  52. pmc Prospective evaluation of clinical and biological markers to predict the outcome of invasive pulmonary aspergillosis in hematological patients
    Anne Bergeron
    Universite Paris Diderot, Sorbonne Paris Cité, Service de Pneumologie, AP HP, Hopital Saint Louis, Paris, France
    J Clin Microbiol 50:823-30. 2012
    ....
  53. pmc β-1,3-glucan modifying enzymes in Aspergillus fumigatus
    Isabelle Mouyna
    Unite des Aspergillus, Département de Parasitologie et Mycologie, Institut Pasteur Paris, France
    Front Microbiol 4:81. 2013
    ..Based on in silico and experimental data, this review gives an overview of β-1,3-glucan modifying enzymes in A. fumigatus genome and their putative role during morphogenesis...
  54. pmc Conidial hydrophobins of Aspergillus fumigatus
    Sophie Paris
    Unite des Aspergillus, Département Structure et Dynamique des Génomes, Institut Pasteur, 25 rue du Docteur Roux, F 75724 Paris, France
    Appl Environ Microbiol 69:1581-8. 2003
    ..Moreover, rodletless mutants are more sensitive to killing by alveolar macrophages, suggesting that RodAp or the rodlet structure is involved in the resistance to host cells...
  55. pmc Aspergillus fumigatus-induced interleukin-8 synthesis by respiratory epithelial cells is controlled by the phosphatidylinositol 3-kinase, p38 MAPK, and ERK1/2 pathways and not by the toll-like receptor-MyD88 pathway
    Viviane Balloy
    Unité de Défense Innée et Inflammation, Institut Pasteur, Paris 75015, France
    J Biol Chem 283:30513-21. 2008
    ..fumigatus, one that is MyD88-dependent and another that is My88-independent and involved in IL-8 synthesis...
  56. pmc Dandruff is associated with disequilibrium in the proportion of the major bacterial and fungal populations colonizing the scalp
    Cecile Clavaud
    Unite des Aspergillus, Institut Pasteur, Paris, France
    PLoS ONE 8:e58203. 2013
    ..acnes compared to the control population (p<0.05). These results suggested for the first time using molecular methods, that dandruff is linked to the balance between bacteria and fungi of the host scalp surface...
  57. ncbi request reprint Undressing the fungal cell wall/cell membrane--the antifungal drug targets
    Rui Tada
    Unite des Aspergillus, Institut Pasteur, Paris, France
    Curr Pharm Des 19:3738-47. 2013
    ....
  58. pmc The diverse applications of RNA-seq for functional genomic studies in Aspergillus fumigatus
    Antonis Rokas
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA
    Ann N Y Acad Sci 1273:25-34. 2012
    ..These results demonstrate the utility and potential of RNA-seq for functional genomics studies in A. fumigatus and other fungal human pathogens...
  59. ncbi request reprint Glycosylinositolphosphoceramides in Aspergillus fumigatus
    Catherine Simenel
    Unité de Résonance Magnétique Nucléaire des Biomolécules, CNRS URA 2185 Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Glycobiology 18:84-96. 2008
    ..Interestingly, this galactofuranose residue could be substituted by a choline-phosphate group, as observed only in the GIPC of Acremonium sp., a plant pathogen...