S Laperche

Summary

Affiliation: Institut National de la Transfusion Sanguine
Country: France

Publications

  1. pmc Simultaneous detection of hepatitis C virus (HCV) core antigen and anti-HCV antibodies improves the early detection of HCV infection
    Syria Laperche
    National Reference Center for Hepatitis B and C in Transfusion, Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015 Paris, France
    J Clin Microbiol 43:3877-83. 2005
  2. ncbi Is an assay for simultaneous detection of hepatitis C virus core antigen and antibody a valuable alternative to nucleic acid testing?
    Syria Laperche
    National Reference Center for Hepatitis B and C in Transfusion, National Institute of Blood Transfusion, Paris, France
    Transfusion 45:1965-72. 2005
  3. doi Multinational assessment of blood-borne virus testing and transfusion safety on the African continent
    Syria Laperche
    National Reference Center for Hepatitis B and C and HIV in Transfusion, National Blood Transfusion Institute, Paris, France
    Transfusion 53:816-26. 2013
  4. doi Blood safety strategies for human T-cell lymphotropic virus in Europe
    S Laperche
    Reference National Centre for hepatitis B et C and HIV in transfusion, Institut National de la Transfusion Sanguine, Paris, France
    Vox Sang 96:104-10. 2009
  5. ncbi A new HCV core antigen assay based on disassociation of immune complexes: an alternative to molecular biology in the diagnosis of early HCV infection
    Syria Laperche
    Department of Blood Transmissible Agents, National Institute of Blood Transfusion, Paris, France
    Transfusion 43:958-62. 2003
  6. ncbi [Recent HCV infections in blood donors (1994-2001)]
    S Laperche
    Unité d expertise en virologie, Centre National de Référence pour les Hépatites B et C en Transfusion, Institut National de la Transfusion Sanguine, 6, rue Alexandre Cabanel, 75015, Paris, France
    Transfus Clin Biol 10:78-80. 2003
  7. pmc Interpretation of real-time PCR results for hepatitis C virus RNA when viral load is below quantification limits
    Syria Laperche
    Centre National de Référence pour les Hépatites B et C en Transfusion, Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, Paris, France
    J Clin Microbiol 49:1113-5. 2011
  8. doi Transfusion safety on the African continent: an international quality control of virus testing in blood banks
    Syria Laperche
    National Reference Center for Hepatitis B and C and HIV in Transfusion, National Blood Transfusion Institute, 6 rue Alexandre Cabanel, F 75015 Paris, France
    Transfusion 49:1600-8. 2009
  9. pmc Expertise of laboratories in viral load quantification, genotyping, and precore mutant determination for hepatitis B virus in a multicenter study
    Syria Laperche
    Centre National de Référence pour les Hépatites B et C en Transfusion, Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, Paris, France
    J Clin Microbiol 44:3600-7. 2006
  10. ncbi A revised method for estimating hepatitis B virus transfusion residual risk based on antibody to hepatitis B core antigen incident cases
    Syria Laperche
    Centre National de Référence pour les Hépatites B et C en Transfusion, Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, Paris, France
    Transfusion 48:2308-14. 2008

Collaborators

Detail Information

Publications44

  1. pmc Simultaneous detection of hepatitis C virus (HCV) core antigen and anti-HCV antibodies improves the early detection of HCV infection
    Syria Laperche
    National Reference Center for Hepatitis B and C in Transfusion, Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015 Paris, France
    J Clin Microbiol 43:3877-83. 2005
    ....
  2. ncbi Is an assay for simultaneous detection of hepatitis C virus core antigen and antibody a valuable alternative to nucleic acid testing?
    Syria Laperche
    National Reference Center for Hepatitis B and C in Transfusion, National Institute of Blood Transfusion, Paris, France
    Transfusion 45:1965-72. 2005
    ....
  3. doi Multinational assessment of blood-borne virus testing and transfusion safety on the African continent
    Syria Laperche
    National Reference Center for Hepatitis B and C and HIV in Transfusion, National Blood Transfusion Institute, Paris, France
    Transfusion 53:816-26. 2013
    ..For this reason, the World Health Organization has recommended a quality control (QC) system for African blood centers...
  4. doi Blood safety strategies for human T-cell lymphotropic virus in Europe
    S Laperche
    Reference National Centre for hepatitis B et C and HIV in transfusion, Institut National de la Transfusion Sanguine, Paris, France
    Vox Sang 96:104-10. 2009
    ..Furthermore, leucoreduction of blood components has been implemented to preclude the transmission of infectious agents present in white blood cells...
  5. ncbi A new HCV core antigen assay based on disassociation of immune complexes: an alternative to molecular biology in the diagnosis of early HCV infection
    Syria Laperche
    Department of Blood Transmissible Agents, National Institute of Blood Transfusion, Paris, France
    Transfusion 43:958-62. 2003
    ..An EIA based on immune complex disassociation of nucleocapsid proteins of HCV has been developed to detect and quantify HCV core antigen...
  6. ncbi [Recent HCV infections in blood donors (1994-2001)]
    S Laperche
    Unité d expertise en virologie, Centre National de Référence pour les Hépatites B et C en Transfusion, Institut National de la Transfusion Sanguine, 6, rue Alexandre Cabanel, 75015, Paris, France
    Transfus Clin Biol 10:78-80. 2003
  7. pmc Interpretation of real-time PCR results for hepatitis C virus RNA when viral load is below quantification limits
    Syria Laperche
    Centre National de Référence pour les Hépatites B et C en Transfusion, Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, Paris, France
    J Clin Microbiol 49:1113-5. 2011
    ..5 to 500 IU/ml) showed a score of correct results of up to 93.5%. However, 55.6% of the laboratories did not follow the recommendations for the interpretation of their results, leading to ambiguous conclusions...
  8. doi Transfusion safety on the African continent: an international quality control of virus testing in blood banks
    Syria Laperche
    National Reference Center for Hepatitis B and C and HIV in Transfusion, National Blood Transfusion Institute, 6 rue Alexandre Cabanel, F 75015 Paris, France
    Transfusion 49:1600-8. 2009
    ....
  9. pmc Expertise of laboratories in viral load quantification, genotyping, and precore mutant determination for hepatitis B virus in a multicenter study
    Syria Laperche
    Centre National de Référence pour les Hépatites B et C en Transfusion, Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, Paris, France
    J Clin Microbiol 44:3600-7. 2006
    ..Furthermore, the clinical implications of HBV genotyping and the determination of precore/core mutants need to be clearly stated to justify the standardization of these methods...
  10. ncbi A revised method for estimating hepatitis B virus transfusion residual risk based on antibody to hepatitis B core antigen incident cases
    Syria Laperche
    Centre National de Référence pour les Hépatites B et C en Transfusion, Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, Paris, France
    Transfusion 48:2308-14. 2008
    ....
  11. ncbi [Genetic diversity of human erythroviruses. Consequences on infectious safety of plasma derivatives]
    A Servant-Delmas
    Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, 6, rue Alexandre Cabanel, 75015 Paris, France
    Transfus Clin Biol 16:482-8. 2009
    ..Recently, a new human parvovirus (PARV4) has been discovered. The consequences on blood transfusion of this blood-borne agent and its pathogenicity are still unknown...
  12. ncbi Determination of hepatitis B virus subtypes by an enzyme immunoassay method using monoclonal antibodies to type-specific epitopes of HBsAg
    S Laperche
    Unité de Virologie Transfusionnelle, Institut National de la Transfusion Sanguine, Paris, France
    J Viral Hepat 8:447-53. 2001
    ....
  13. ncbi Efficacy of HCV core antigen detection during the preseroconversion period
    A M Courouce
    Department of Virology, National Institute of Blood Transfusion, Lille, France
    Transfusion 40:1198-202. 2000
    ..The purpose of this study was to compare the performances of HCV core antigen (HCV Ag) testing with HCV RNA detection during the preseroconversion period...
  14. doi High levels of serum hepatitis B virus DNA in patients with 'anti-HBc alone': role of HBsAg mutants
    O Launay
    Universite Paris Descartes, Faculte de Medecine, Paris, France
    J Viral Hepat 18:721-9. 2011
    ....
  15. ncbi Blood donors infected with the hepatitis B virus but persistently lacking antibodies to the hepatitis B core antigen
    S Laperche
    Unité de Virologie Transfusionnelle, Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75739 Paris, France
    Vox Sang 80:90-4. 2001
    ..Through a national epidemiological survey, two young and first-time blood donors, originating from HBV-endemic areas, were identified as HBV carriers with an absence of anti-HBc reactivity...
  16. ncbi [Genetic diversity of human Erythroviruses]
    A Servant-Delmas
    Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, 6, rue Alexandre Cabanel, 75739 Paris cedex 15, France
    Pathol Biol (Paris) 57:167-74. 2009
    ..A prospective French study performed between 1999 and 2001 indicated that genotypes 2 and 3 viruses circulated with a significant frequency (10%). Pathogenic properties might not differ according to the genotype...
  17. ncbi Lessons from a multicentre study of the detectability of viral genomes based on a two-round quality control of GB virus C (GBV-C)/hepatitis G virus (HGV) polymerase chain reaction assay
    J J Lefrere
    Unité de recherches biocliniques, Institut National de la Transfusion Sanguine, Paris, France
    J Virol Methods 85:117-24. 2000
    ....
  18. ncbi Sensitivity of hepatitis B virus DNA transcription-mediated amplification testing in hepatitis B surface antigen-positive blood donations
    Françoise Bouchardeau
    Expertise unit of Virology, National Reference Center for Hepatitis B and C Viruses in Transfusion, National Institute of Blood Transfusion, Paris, France
    Transfusion 46:2047-52. 2006
    ..The objective was to evaluate the performance of nucleic acid testing (NAT) in the detection of hepatitis B virus (HBV) infection in hepatitis B surface antigen (HBsAg)-positive blood donations...
  19. doi Hepatitis G virus: a suitable marker of in vivo efficacy for pathogen inactivation
    J J Lefrere
    Department of Blood Transmissible Agents, National Institute of Blood Transfusion, Paris, France
    Vox Sang 95:76-8. 2008
    ..The in vivo efficacy of pathogen inactivation methods could be assessed by the absence of hepatitis G virus markers after transfusion of pathogen-inactivated blood products, in recipients susceptible to infection before the transfusion...
  20. ncbi [Safety of blood products and B19 parvovirus]
    J J Lefrere
    Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, 6, rue Alexandre Cabanel, 75709 Paris cedex 15, France
    Transfus Clin Biol 13:235-41. 2006
    ..If not, a screening of blood donors positive for B19 IgG would be a sufficient preventive measure...
  21. ncbi Outbreak of hepatitis C virus infection in a hemodialysis unit: potential transmission by the hemodialysis machine?
    Elisabeth Delarocque-Astagneau
    Institut de Veille Sanitaire, Paris, France
    Infect Control Hosp Epidemiol 23:328-34. 2002
    ..To identify the routes of transmission during an outbreak of infection with hepatitis C virus (HCV) genotype 2a/2c in a hemodialysis unit...
  22. pmc Comparison of hepatitis C virus NS5b and 5' noncoding gene sequencing methods in a multicenter study
    Syria Laperche
    Centre National de Référence pour les Hépatites B et C en Transfusion, Département des Agents Transmissible par le Sang, Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015 Paris, France
    J Clin Microbiol 43:733-9. 2005
    ....
  23. doi Impact of hepatitis B virus genotypes and surface antigen variants on the performance of HBV real time PCR quantification
    Vincent Thibault
    Laboratoire de Virologie, AP HP Hôpital de la Pitié Salpêtrière, Paris, France
    J Virol Methods 159:265-70. 2009
    ..In conclusion, the Abbott RT assay can detect and quantify DNA from different HBV variants with equivalent performance and is thus suitable for routine monitoring of patients with chronic HBV infections...
  24. pmc Unique NS5b hepatitis C virus gene sequence consensus database is essential for standardization of genotype determinations in multicenter epidemiological studies
    Syria Laperche
    Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015 Paris, France
    J Clin Microbiol 44:614-6. 2006
    ....
  25. pmc Improvement of hepatitis C virus (HCV) genotype determination with the new version of the INNO-LiPA HCV assay
    Françoise Bouchardeau
    Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015 Paris, France
    J Clin Microbiol 45:1140-5. 2007
    ..Thus, the Versant HCV Genotype 2.0 assay remains a useful tool for clinical practice when only the discrimination between major HCV genotypes is necessary...
  26. pmc Genetic diversity within human erythroviruses: identification of three genotypes
    Annabelle Servant
    Laboratoire de Virologie, Hopital Armand Trousseau, EA2391, UFR Saint Antoine, Paris, France
    J Virol 76:9124-34. 2002
    ....
  27. ncbi Complete or partial seroreversion in immunocompetent individuals after self-limited HCV infection: consequences for transfusion
    Jean Jacques Lefrere
    Laboratory of Hematology, Hospital of Amiens, Paris, France
    Transfusion 44:343-8. 2004
    ..However, it has important implications in the context of transfusion inquiries, in particular in case of a blood donor suspected to have transmitted HCV through a past blood donation...
  28. pmc Multicenter trials need to use the same assay for hepatitis C virus viral load determination
    Syria Laperche
    Centre National de Référence pour les Hépatites B et C en Transfusion, Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015, Paris, France
    J Clin Microbiol 45:3788-90. 2007
    ..This underlines the importance of using the same assay in multicenter studies or when monitoring antiviral therapy...
  29. ncbi HIV antibody screening remains indispensable for ensuring viral safety of blood components despite NAT implementation
    Syria Laperche
    Study Unit of Blood Borne Agents and National Reference Center on Post transfusion Hepatitis, National Institute of Blood Transfusion, Paris, France
    Transfusion 43:1428-32. 2003
    ..Because this new screening procedure theoretically covers the entire period of infectivity, the necessity for maintaining serologic assays in blood screening strategy could become questionable...
  30. ncbi Persistent B19 infection in immunocompetent individuals: implications for transfusion safety
    Jean Jacques Lefrere
    Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015 Paris, France
    Blood 106:2890-5. 2005
    ....
  31. pmc Overestimation of incidence of hepatitis B virus mixed-genotype infections by use of the new line probe INNO-LiPA genotyping assay
    Mélanie Mercier
    National Reference Center for Hepatitis B and C in Blood Transfusion, Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015 Paris, France
    J Clin Microbiol 49:1154-6. 2011
    ..Our study demonstrates that INNO-LiPA overestimates mixed infections as a result of erroneous genotype H detection...
  32. ncbi An incident case-control study of modes of hepatitis C virus transmission in France
    Elisabeth Delarocque-Astagneau
    From the Institut de Veille Sanitaire, Saint Maurice cedex, France
    Ann Epidemiol 17:755-62. 2007
    ..We undertook a case-control study of incident HCV infection to identify persistent modes of transmission in France...
  33. ncbi Alternatives to nucleic acid testing in the blood transfusion service
    Syria Laperche
    Lancet 360:1519. 2002
  34. ncbi HIV-1 and HCV infections among antibody-negative blood donors
    Syria Laperche
    N Engl J Med 351:2232-5; author reply 2232-5. 2004
  35. ncbi Molecular characterization of genotype 2 and 4 hepatitis C virus isolates in French blood donors
    Jean Francois Cantaloube
    Unité Emergence et coévolution virale, UMR 6578, CNRS Etablissement Français du Sang Alpes Méditerranée, Marseille, France
    J Med Virol 80:1732-9. 2008
    ..The inferred histories of population growth indicated that transmission rates differed according to HCV subtype. These results may help to predict the future burden of HCV in France...
  36. pmc Analysis of the 5' noncoding region versus the NS5b region in genotyping hepatitis C virus isolates from blood donors in France
    Jean Francois Cantaloube
    Unité des Virus Emergents EA3292, Etablissement Francais du Sang Alpes Mediterranee, 149 bd Baille, 13005 Marseille, France
    J Clin Microbiol 44:2051-6. 2006
    ..Sequence analysis of the NS5b region is mandatory for epidemiologic studies...
  37. pmc Group o human immunodeficiency virus type 1 infection that escaped detection in two immmunoassays
    Said Zouhair
    Department of Biology, Hopital de Versailles, 177 rue de Versailles, Le Chesnay 78150, France
    J Clin Microbiol 44:662-5. 2006
    ..The sera were strongly reactive to the V3 peptide of group O but not to the gp41 immunodominant epitope. Gp41 was sequenced, confirming that this virus belonged to group O...
  38. ncbi Prevalence of Borna disease virus RNA in populations at high or low risk for blood-borne infections
    Jean Jacques Lefrere
    Transfusion 44:1396. 2004
  39. doi Antigen-antibody combination assays for blood donor screening: weighing the advantages and costs
    Syria Laperche
    Transfusion 48:576-9. 2008
  40. pmc Performance of the Cobas AmpliPrep/Cobas TaqMan real-time PCR assay for hepatitis B virus DNA quantification
    Stephane Chevaliez
    French National Reference Center for Viral Hepatitis B, C and delta, Department of Virology, Hopital Henri Mondor, Universite Paris 12
    J Clin Microbiol 46:1716-23. 2008
    ..Samples with HBV DNA concentrations above the upper limit of quantification need to be diluted and then retested. Broad use of fully automated real-time PCR assays should improve the management of patients with chronic HBV infection...
  41. doi Repository of blood samples from recipients of red blood cell transfusions in France
    Jean Jacques Lefrere
    Transfusion 48:195; author reply 195-6. 2008
  42. pmc Sensitivities of four new commercial hepatitis B virus surface antigen (HBsAg) assays in detection of HBsAg mutant forms
    Thoai Duong Ly
    Laboratoire Claude Levy, 78 av de Verdun, 94200 Ivry sur Seine, France
    J Clin Microbiol 44:2321-6. 2006
    ..The prevalence and clinical impact of HBsAg mutants are under investigation. However, the manufacturers must be vigilant in the design of the assays in order to reduce the risk of missing a broad range of described S gene mutants...
  43. ncbi Trends in residual risk of transfusion-transmitted viral infections in France between 1992 and 2000
    Josiane Pillonel
    National Institute for Public Health Surveillance, Saint Maurice, France
    Transfusion 42:980-8. 2002
    ..Monitoring trends in residual risks of transfusion-transmitted viral infections (HIV, HTLV, HBV, and HCV) is important to assess improvements in blood safety. In France, theses trends were analyzed between 1992 and 2000...
  44. ncbi Human immunodeficiency virus type 1 incidence among blood donors in France, 1992 through 2006: use of an immunoassay to identify recent infections
    Josiane Pillonel
    Institut de Veille Sanitaire, Departement des Maladies Infectieuses, Saint Maurice, France
    Transfusion 48:1567-75. 2008
    ..The characteristics of recently infected donors, estimates of HIV-1 incidence, and the residual risk of transfusion-transmitted HIV-1 are presented, in both first-time and repeat donors...