Isabelle Landrieu

Summary

Affiliation: Institut de Biologie de Lille
Country: France

Publications

  1. ncbi Characterization of the Arabidopsis thaliana Arath;CDC25 dual-specificity tyrosine phosphatase
    Isabelle Landrieu
    UMR 8525 CNRS Lille2, Institut de Biologie de Lille Pasteur Institute of Lille, 59019 Lille Cedex, France
    Biochem Biophys Res Commun 322:734-9. 2004
  2. pmc A small CDC25 dual-specificity tyrosine-phosphatase isoform in Arabidopsis thaliana
    Isabelle Landrieu
    Unité Mixte de Recherche 8525 Centre National de la Recherche Scientifique Lille2, Institut de Biologie de Lille Pasteur Institute of Lille, 59019 Lille Cedex, France
    Proc Natl Acad Sci U S A 101:13380-5. 2004
  3. ncbi Solution structure of the single-domain prolyl cis/trans isomerase PIN1At from Arabidopsis thaliana
    Isabelle Landrieu
    UMR 8525 CNRS Lille2, Institut de Biologie de Lille Pasteur Institute of Lille, 59019 Lille Cedex, France
    J Mol Biol 320:321-32. 2002
  4. ncbi NMR analysis of a Tau phosphorylation pattern
    Isabelle Landrieu
    CNRS UMR 8525, Institut Pasteur de Lille, 59019 Lille Cedex, France
    J Am Chem Soc 128:3575-83. 2006
  5. ncbi Solution NMR study of the monomeric form of p13suc1 protein sheds light on the hinge region determining the affinity for a phosphorylated substrate
    Benoit Odaert
    CNRS Université de Lille 2 UMR 8525, Institut Pasteur de Lille Institut de Biologie de Lille, 59019 Lille Cedex, France
    J Biol Chem 277:12375-81. 2002
  6. ncbi Structural analysis of Escherichia coli OpgG, a protein required for the biosynthesis of osmoregulated periplasmic glucans
    Xavier Hanoulle
    UMR 8525 CNRS, Institut de Biologie de Lille, Universite de Lille II, 1 rue du Professeur Calmette, BP447, 59021, France
    J Mol Biol 342:195-205. 2004
  7. ncbi Regions of tau implicated in the paired helical fragment core as defined by NMR
    Alain Sillen
    CNRS Université de Lille 2 UMR 8525, Institut Pasteur de Lille, B P 245, 59019 Lille Cedex, France
    Chembiochem 6:1849-56. 2005
  8. pmc Plasmodium falciparum inhibitor-3 homolog increases protein phosphatase type 1 activity and is essential for parasitic survival
    Aline Fréville
    Center for Infection and Immunity of Lille, INSERM U1019 CNRS UMR 8204, University of Lille Nord de France, Institut Pasteur de Lille, 1 rue du Professeur Calmette, 59019 Lille Cedex, France
    J Biol Chem 287:1306-21. 2012
  9. ncbi Structural impact of heparin binding to full-length Tau as studied by NMR spectroscopy
    Nathalie Sibille
    CNRS UMR 8576, Unite de Glycobiologie Structurale et Fonctionnelle, Université des Sciences et Technologies de Lille 1, 59655, Villeneuve d Ascq Cedex, France
    Biochemistry 45:12560-72. 2006
  10. ncbi Exploring the molecular function of PIN1 by nuclear magnetic resonance
    Isabelle Landrieu
    CNRS UMR 8576, Universite des Sciences et Technologies de Lille, 59655 Villeneuve d Ascq, France
    Curr Protein Pept Sci 7:179-94. 2006

Collaborators

  • G Lippens
  • Dirk Inze
  • Lieven De Veylder
  • René Wintjens
  • Klaas Vandepoele
  • Florence Corellou
  • Harald Schwalbe
  • Xavier Hanoulle
  • Alain R Baulard
  • Alexandre Wohlkonig
  • Thomas Langer
  • Jean Pierre Bohin
  • Jean Michel Wieruszeski
  • Caroline Smet
  • Alain Sillen
  • Arnaud Leroy
  • Luc Buee
  • Jean Francois Bodart
  • Malika Hamdane
  • Benoit Odaert
  • Aline Fréville
  • Anne Véronique Sambo
  • Vanessa Dehennaut
  • Hélène Hodak
  • Sophie Rodius
  • Jean Pierre Vilain
  • Nathalie Sibille
  • Marco da Costa
  • Patrice Delobel
  • Andre Delacourte
  • Séverine Bégard
  • Klaas Dijkstra
  • Peter Casteels
  • Gea Schuurman-Wolters
  • Ruud Scheek
  • Jamal Khalife
  • Elisabeth Werkmeister
  • Pascual Sanz
  • Muriel Montbarbon
  • Benjamin Bertin
  • M Adelaida García-Gimeno
  • Christine Pierrot
  • Jerome Vicogne
  • Hadidjatou Kalamou
  • Alexis Verger
  • Francoise Jacob-Dubuisson
  • Laziza Amniai
  • Caroline Smet-Nocca
  • Jean Claude Michalski
  • Arlette Rousseau-Lescuyer
  • Olivier Chaloin
  • Ji Zhang
  • Magalie Senechal
  • Hervé Drobecq
  • Elisabeth Schaffner-Reckinger
  • Tony Lefebvre
  • Nelly Kieffer
  • Marc Jamin
  • Camille Locht
  • Minghui Lin
  • Michèle Moes
  • Sylvie Lefebvre
  • Vincent Peyrot
  • Pascale Barbier
  • Lien Bach
  • Jean Denis Faure
  • Spencer Brown
  • Olivier Catrice
  • Yannick Bellec
  • Barbara Mulloy
  • Anne Loyens
  • Jean Frederic Duckert
  • Amena Ben Younes
  • Benoit Deprez
  • Jean Claude Beauvillain
  • Anne Violleau
  • Stephane Flament
  • Claude Alain Maurage
  • Dragos Horvath
  • Nicolas Sergeant
  • Antoine Ghestem

Detail Information

Publications30

  1. ncbi Characterization of the Arabidopsis thaliana Arath;CDC25 dual-specificity tyrosine phosphatase
    Isabelle Landrieu
    UMR 8525 CNRS Lille2, Institut de Biologie de Lille Pasteur Institute of Lille, 59019 Lille Cedex, France
    Biochem Biophys Res Commun 322:734-9. 2004
    ..The presence of a metal ion in the C-terminus of this new protein points to a zinc finger, and sequence homology indicates that this new structural element might be conserved in related plant homologs...
  2. pmc A small CDC25 dual-specificity tyrosine-phosphatase isoform in Arabidopsis thaliana
    Isabelle Landrieu
    Unité Mixte de Recherche 8525 Centre National de la Recherche Scientifique Lille2, Institut de Biologie de Lille Pasteur Institute of Lille, 59019 Lille Cedex, France
    Proc Natl Acad Sci U S A 101:13380-5. 2004
    ..We conclude that despite sequence divergence, Arath;CDC25 is structurally and functionally an isoform of the CDC25 superfamily, which is conserved in yeast and in plants, including Arabidopsis and rice...
  3. ncbi Solution structure of the single-domain prolyl cis/trans isomerase PIN1At from Arabidopsis thaliana
    Isabelle Landrieu
    UMR 8525 CNRS Lille2, Institut de Biologie de Lille Pasteur Institute of Lille, 59019 Lille Cedex, France
    J Mol Biol 320:321-32. 2002
    ..Based on our experimental results and the molecular specificities of the PIN1At enzyme, functional implications of the lack of WW domains in this plant PIN-type PPIase will be discussed...
  4. ncbi NMR analysis of a Tau phosphorylation pattern
    Isabelle Landrieu
    CNRS UMR 8525, Institut Pasteur de Lille, 59019 Lille Cedex, France
    J Am Chem Soc 128:3575-83. 2006
    ..We finally demonstrate that the NMR approach can equally be used to evaluate potential kinase inhibitors in a straightforward manner...
  5. ncbi Solution NMR study of the monomeric form of p13suc1 protein sheds light on the hinge region determining the affinity for a phosphorylated substrate
    Benoit Odaert
    CNRS Université de Lille 2 UMR 8525, Institut Pasteur de Lille Institut de Biologie de Lille, 59019 Lille Cedex, France
    J Biol Chem 277:12375-81. 2002
    ....
  6. ncbi Structural analysis of Escherichia coli OpgG, a protein required for the biosynthesis of osmoregulated periplasmic glucans
    Xavier Hanoulle
    UMR 8525 CNRS, Institut de Biologie de Lille, Universite de Lille II, 1 rue du Professeur Calmette, BP447, 59021, France
    J Mol Biol 342:195-205. 2004
    ..The structural data suggest that OpgG is an OPG branching enzyme in which the catalytic activity is located in the large N-terminal domain and controlled via the smaller C-terminal domain...
  7. ncbi Regions of tau implicated in the paired helical fragment core as defined by NMR
    Alain Sillen
    CNRS Université de Lille 2 UMR 8525, Institut Pasteur de Lille, B P 245, 59019 Lille Cedex, France
    Chembiochem 6:1849-56. 2005
    ..Hence, our data give a more precise picture of the dynamics of tau when it is integrated into mature filaments and should provide further understanding of the molecular processes that govern aggregation...
  8. pmc Plasmodium falciparum inhibitor-3 homolog increases protein phosphatase type 1 activity and is essential for parasitic survival
    Aline Fréville
    Center for Infection and Immunity of Lille, INSERM U1019 CNRS UMR 8204, University of Lille Nord de France, Institut Pasteur de Lille, 1 rue du Professeur Calmette, 59019 Lille Cedex, France
    J Biol Chem 287:1306-21. 2012
    ..The main localization of a GFP-tagged PfI3 in the nucleus of all blood stage parasites is compatible with a regulatory role of PfI3 on the activity of nuclear PfPP1...
  9. ncbi Structural impact of heparin binding to full-length Tau as studied by NMR spectroscopy
    Nathalie Sibille
    CNRS UMR 8576, Unite de Glycobiologie Structurale et Fonctionnelle, Université des Sciences et Technologies de Lille 1, 59655, Villeneuve d Ascq Cedex, France
    Biochemistry 45:12560-72. 2006
    ..Heparin thus becomes integrated into the rigid core region of the PHF, probably providing the charge compensation for the lysine-rich stretches that form upon the in-register, parallel stacking of the repeat regions...
  10. ncbi Exploring the molecular function of PIN1 by nuclear magnetic resonance
    Isabelle Landrieu
    CNRS UMR 8576, Universite des Sciences et Technologies de Lille, 59655 Villeneuve d Ascq, France
    Curr Protein Pept Sci 7:179-94. 2006
    ..Finally, isomerization catalysis is thought to regulate the (de)phosphorylation of specific pThr/pSer-Pro motifs, exemplified by the stimulation of the dephosphorylation of pThr231 of Tau by the PP2A phosphatase...
  11. pmc Arabidopsis PASTICCINO2 is an antiphosphatase involved in regulation of cyclin-dependent kinase A
    Marco da Costa
    Laboratoire de Biologie Cellulaire, Institut National de la Recherche Agronomique, F 78026 Versailles Cedex, France
    Plant Cell 18:1426-37. 2006
    ....
  12. ncbi Pin1: a therapeutic target in Alzheimer neurodegeneration
    Malika Hamdane
    INSERM U422, IMPRT, Place de Verdun, Lille, France
    J Mol Neurosci 19:275-87. 2002
    ..The involvement of Pin1 in the G0/G1 transition in neurons points to its function as a good target for the development of new therapeutic strategies in neurodegenerative disorders...
  13. ncbi Control of protein-protein interactions: structure-based discovery of low molecular weight inhibitors of the interactions between Pin1 WW domain and phosphopeptides
    Caroline Smet
    CNRS University of Lille 2 UMR 8525, Institut Pasteur de Lille, Molecular Drug Discovery, 3 rue du Professeur Laguesse, 59000 Lille, France
    J Med Chem 48:4815-23. 2005
    ..Our structure-based strategy implies the synthesis of analogues of the Ac-Thr(PO(3)H(2))-Pro-NH(2) dipeptide and relies on high resolution NMR spectroscopy to accurately measure the affinity constants even in the high micromolar range...
  14. ncbi High-resolution magic angle spinning NMR of the neuronal tau protein integrated in Alzheimer's-like paired helical fragments
    Alain Sillen
    CNRS Université de Lille 2 UMR 8525 and Inserm IFR17, Institut Pasteur de Lille, BP 245 F 59019 Lille Cedex, France
    J Am Chem Soc 127:10138-9. 2005
    ..HRMAS NMR of tau paired helical fragments assembled with heparin show an intensity decrease for those amino acids that are incorporated into the rigid core region, whereas the N-terminal amino acids maintain their full mobility...
  15. ncbi Regulation of Pin1 peptidyl-prolyl cis/trans isomerase activity by its WW binding module on a multi-phosphorylated peptide of Tau protein
    Caroline Smet
    UMR CNRS 8525 Structure et fonction des Biomolecules, Institut de Biologie de Lille, Institut Pasteur de Lille, BP 245 F 59019 Lille Cedex, France
    FEBS Lett 579:4159-64. 2005
    ..We therefore conclude that the WW domain can act as a negative regulator of enzymatic activity when multiple phosphorylation is present, thereby suggesting a subtle mechanism of its functional regulation...
  16. ncbi Proline-directed random-coil chemical shift values as a tool for the NMR assignment of the tau phosphorylation sites
    Guy Lippens
    CNRS Université de Lille 2 UMR 8525, Institut Pasteur de Lille, BP 245 59019 Lille Cedex, France
    Chembiochem 5:73-8. 2004
    ..This is a first step toward the study of the phosphorylation of Tau by NMR spectroscopy...
  17. ncbi Studying the natively unfolded neuronal Tau protein by solution NMR spectroscopy
    Guy Lippens
    CNRS Université de Lille2 UMR 8525, Institut Pasteur de Lille, 1 rue du Professeur Calmette, BP 245, 59019 Lille Cedex France
    Protein Pept Lett 13:235-46. 2006
    ..Preliminary NMR data on the fibers show that the assignment enables a precise mapping of the rigid core. Future NMR experiments should allow one to gain more insight into the conformational aspects of this intriguing protein...
  18. pmc The talin rod IBS2 alpha-helix interacts with the beta3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges
    Sophie Rodius
    Laboratoire de Biologie et Physiologie Intégrée CNRS GDRE ITI, Université du Luxembourg, L 1511 Luxembourg, Grand Duchy of Luxembourg
    J Biol Chem 283:24212-23. 2008
    ....
  19. doi NMR observation of Tau in Xenopus oocytes
    Jean Francois Bodart
    Laboratoire de Régulation des Signaux de Division, EA4020, Building SN3, Universite des Sciences et Technologies de Lille, 59655 Villeneuve d Ascq, France
    J Magn Reson 192:252-7. 2008
    ..When injecting Tau protein into immature oocytes, we show that both its microtubule association and different phosphorylation events can be detected...
  20. doi Microinjection of recombinant O-GlcNAc transferase potentiates Xenopus oocytes M-phase entry
    Vanessa Dehennaut
    UMR CNRS 8576, UGSF, USTL, IFR 147, 59655 Villeneuve d Ascq, France
    Biochem Biophys Res Commun 369:539-46. 2008
    ..Microinjection of anti-OGT antibodies leads to a delay of the GVBD kinetics. Our results hence demonstrate that OGT is a key molecule for the timely progression of the cell cycle...
  21. doi The peptidyl-prolyl isomerase and chaperone Par27 of Bordetella pertussis as the prototype for a new group of parvulins
    Hélène Hodak
    INSERM U629, Lille, France
    J Mol Biol 376:414-26. 2008
    ..Par27 displays both PPIase and chaperone activities in vitro. In vivo, Par27 might function as a general periplasmic chaperone in B. pertussis...
  22. ncbi Structural and functional characterization of the interaction between cyclophilin B and a heparin-derived oligosaccharide
    Xavier Hanoulle
    Structural and Functional Glycobiology Unit, UMR 8576 CNRS, University of Sciences and Technologies of Lille, 59655 Villeneuve d Ascq, France
    J Biol Chem 282:34148-58. 2007
    ..We thus conclude that the glycanic moiety of HSPG serves as anchor for CypB at the cell surface, and that the signal could be transduced by CypB via its PPIase activity toward CD147...
  23. ncbi NMR investigation of the interaction between the neuronal protein tau and the microtubules
    Alain Sillen
    CNRS UMR 8576 Unité de Glycobiologie Structurale et Fonctionnelle, Université des Sciences et Technologies de Lille 1, 59655, Villeneuve d Ascq Cedex, France
    Biochemistry 46:3055-64. 2007
    ..The presence of an intramolecular disulfide bridge, on the contrary, does lead to a partial detachment of the C-terminus of Tau, and decreases significantly the overloading of Tau on the MT surface...
  24. ncbi Monitoring of the ethionamide pro-drug activation in mycobacteria by (1)H high resolution magic angle spinning NMR
    Xavier Hanoulle
    CNRS, Université de Lille 2 UMR 8525, Institut de Biologie de Lille, Institut Pasteur de Lille, 1 rue du Professeur Calmette, BP447, 59021 Lille Cedex, France
    Biochem Biophys Res Commun 331:452-8. 2005
    ..The comparison of the metabolite NMR signature with that of synthetic molecules proves the non-identity of ETH* with the ETH derivatives described previously in the literature...
  25. ncbi Selective intracellular accumulation of the major metabolite issued from the activation of the prodrug ethionamide in mycobacteria
    Xavier Hanoulle
    UMR 8525 CNRS Universíté de Lille 2 Lille, F 59021, France
    J Antimicrob Chemother 58:768-72. 2006
    ..Activation pathways of prodrugs are generally problematic to uncover as they produce intermediates potentially difficult to characterize, to purify and that might prove unstable outside of their cellular context...
  26. ncbi Neurofibrillary degeneration of the Alzheimer-type: an alternate pathway to neuronal apoptosis?
    Malika Hamdane
    INSERM U422, Institut de Médecine Prédictive et Recherche Thérapeutique, Place de Verdun, F 59045 Lille Cedex, France
    Biochem Pharmacol 66:1619-25. 2003
    ....
  27. ncbi ELISE NMR: experimental liquid sealing of NMR samples
    Jean Michel Wieruszeski
    CNRS Université de Lille 1 UMR 8576, USTL, Villeneuve d Ascq, France
    J Magn Reson 181:199-202. 2006
    ..For chloroform samples, a simple drop of water allows to efficiently seal the sample, avoiding solvent evaporation even over lengthy time periods...
  28. ncbi Accepting its random coil nature allows a partial NMR assignment of the neuronal Tau protein
    Caroline Smet
    CNRS Université de Lille 2, UMR 8525, Institut Pasteur de Lille, B P 245, 59019 Lille, France
    Chembiochem 5:1639-46. 2004
    ..The obtained assignments equally confirm the absence of regular secondary structure in the isolated protein...
  29. ncbi Assignment of the 1H, 13C and 15N resonances and secondary structure of the monomeric p13suc1 protein of Saccharomyces pombe
    Benoit Odaert
    J Biomol NMR 23:155-6. 2002
  30. ncbi The peptidyl prolyl cis/trans-isomerase Pin1 recognizes the phospho-Thr212-Pro213 site on Tau
    Caroline Smet
    Institut de Biologie de Lille, Institut Pasteur de Lille, UMR CNRS 8525, BP 245, F 59019 Lille cedex, France
    Biochemistry 43:2032-40. 2004
    ....