Research Topics
Genomes and Genes | F KunstSummaryAffiliation: Institut Pasteur Country: France Publications
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Publications
The complete genome sequence of the gram-positive bacterium Bacillus subtilisF Kunst
Institut Pasteur, Unité de Biochimie Microbienne, Paris, France
Nature 390:249-56. 1997....
MecB of Bacillus subtilis, a member of the ClpC ATPase family, is a pleiotropic regulator controlling competence gene expression and growth at high temperatureT Msadek
Unité de Recherche Associée 1300 du Centre National de la Recherche Scientifique, Institut Pasteur, Departement des Biotechnologies, Paris, France
Proc Natl Acad Sci U S A 91:5788-92. 1994..In response to an unknown signal, active ComK would accumulate through a positive feedback loop, leading to expression of competence genes allowing DNA uptake...
Anaerobic transcription activation in Bacillus subtilis: identification of distinct FNR-dependent and -independent regulatory mechanismsH Cruz Ramos
Unité de Régulation de l Expression Génétique, Institut Pasteur, Paris, France
EMBO J 14:5984-94. 1995..Thus induction of genes involved in anaerobic respiration requires in B.subtilis at least two levels of regulation: activation of fnr transcription and activation of FNR to induce transcription of FNR-dependent promoters...
ClpP of Bacillus subtilis is required for competence development, motility, degradative enzyme synthesis, growth at high temperature and sporulationT Msadek
Unité de Biochimie Microbienne, URA 1300 du Centre National de la Recherche Scientifique, Institut Pasteur, Paris, France
Mol Microbiol 27:899-914. 1998..We suggest that ClpP is involved in controlling MecA levels in the cell through proteolysis. Increased levels of MecA in the absence of ClpP are at least partly responsible for the observed pleiotropic phenotype of the delta clpP mutant...
Comparative genomics of Listeria speciesP Glaser
, , Service d'Informatique Scientifique, Institut Pasteur, 25-28 rue du Dr. Roux, 75724 Paris, France
Science 294:849-52. 2001..The presence of 270 L. monocytogenes and 149 L. innocua strain-specific genes (clustered in 100 and 63 islets, respectively) suggests that virulence in Listeria results from multiple gene acquisition and deletion events...
Deduced polypeptides encoded by the Bacillus subtilis sacU locus share homology with two-component sensor-regulator systemsF Kunst
Unité de Biochimie Microbienne, Institut Pasteur, Paris, France
J Bacteriol 170:5093-101. 1988..These similarities suggest that the products of the B. subtilis sacU locus form a sensor-transducer couple, which functions to relay information about specific environmental changes to the transcription apparatus...
Bacillus subtilis F0F1 ATPase: DNA sequence of the atp operon and characterization of atp mutantsM Santana
Unité de Régulation de l Expression Génétique, Institut Pasteur, Paris, France
J Bacteriol 176:6802-11. 1994..It therefore appears that B. subtilis and E. coli respond in similar ways to the absence of oxidative phosphorylation...
The Bacillus subtilis sigL gene encodes an equivalent of sigma 54 from gram-negative bacteriaM Debarbouille
Unité de Biochimie Microbienne, Institut Pasteur, Paris, France
Proc Natl Acad Sci U S A 88:9092-6. 1991..These results indicate that the sigL gene encodes an equivalent of the sigma 54 factor in B. subtilis, to our knowledge, the first of this type to be identified in Gram-positive bacteria...
FindTarget: software for subtractive genome analysisF Chetouani
Laboratoire Génomique des Microorganismes Pathogénes, Institut Pasteur, Departement de Biologie Moleculaire, 25 rue du Dr Roux, 75724 Paris Cedex 15, France
Microbiology 147:2643-9. 2001..The results show that most of the identified genes are clearly involved in cell wall processes, underlining the power of such an approach in general and that of FindTarget in particular...
CAAT-Box, Contigs-Assembly and Annotation Tool-Box for genome sequencing projectsL Frangeul
Genopole, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris 15, France
Bioinformatics 20:790-7. 2004..Using this strategy, the user works with a group of IPFs independently of the closure phase progression. The IPFs are accessible by a web server and can therefore be modified and commented by different groups...
Identification and isolation of a gene required for nitrate assimilation and anaerobic growth of Bacillus subtilisP Glaser
Unité de Régulation de l Expression Génétique, Institut Pasteur, Paris, France
J Bacteriol 177:1112-5. 1995..Analysis of mutants showed that narA but not narQ is required for both nitrate assimilation and respiration...
Characterization of a novel member of the DegS-DegU regulon affected by salt stress in Bacillus subtilisV Dartois
Unité de Biochimie Microbienne, URA 1300 Centre National de la Recherche Scientifique, Institut Pasteur, Paris, France
J Bacteriol 180:1855-61. 1998....
The 102-kilobase pgm locus of Yersinia pestis: sequence analysis and comparison of selected regions among different Yersinia pestis and Yersinia pseudotuberculosis strainsC Buchrieser
Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 75724 Paris Cedex 15, France
Infect Immun 67:4851-61. 1999..Furthermore, sequence comparisons among 29 Yersinia strains suggest that Y. pestis is a recently emerged pathogen that is probably entering the initial phase of reductive evolution...
A gene encoding a tyrosine tRNA synthetase is located near sacS in Bacillus subtilisP Glaser
Unité de Régulation de l Expression Génétique, Institut Pasteur, Paris, France
DNA Seq 1:251-61. 1991..Finally phylogenetic relationships between known tyrosine and tryptophan tRNA synthetases are discussed...
Cloning of a genetically unstable cytochrome P-450 gene cluster involved in degradation of the pollutant ethyl tert-butyl ether by Rhodococcus ruberS Chauvaux
Unité Microbiologie et Environnement and URA 2172, France
J Bacteriol 183:6551-7. 2001..The 5.6-kbp repeat is a class II transposon carrying a TnpA transposase, a truncated form of the recombinase TnpR, and a terminal inverted repeat of 38 bp. The truncated TnpR is encoded by an IS3-interrupted tnpR gene...
Molecular cloning, sequencing, and physiological characterization of the qox operon from Bacillus subtilis encoding the aa3-600 quinol oxidaseM Santana
Unité de Régulation de l Expression Génétique, Institut Pasteur, Paris, France
J Biol Chem 267:10225-31. 1992..Although several terminal oxidases are found in B. subtilis, Qox oxidase (aa3-600) is predominant during the vegetative growth and its absence leads to important alterations of the phenotype of B. subtilis...
Sequence and properties of comQ, a new competence regulatory gene of Bacillus subtilisY Weinrauch
Department of Microbiology, Public Health Research Institute, New York, New York 10016
J Bacteriol 173:5685-93. 1991..These and other results suggest a role for ComQ early in the hierarchy of competence regulatory genes, probably as a component of a signal transduction system...
Whole-genome comparison between Photorhabdus strains to identify genomic regions involved in the specificity of nematode interactionS Gaudriault
Laboratoire EMIP Ecologie Microbienne des Insectes et Interaction Hôtes Pathogène, Universite Montpellier II, UMR1133 INRA UMII, 34095 Montpellier Cedex 5, France
J Bacteriol 188:809-14. 2006..We describe 31 regions belonging to the Photorhabdus flexible gene pool. Distribution analysis of regions among the Photorhabdus genus identified loci possibly involved in nematode specificity...
