Research Topics
Genomes and GenesSpecies | C KaplanSummaryAffiliation: Institut National de la Transfusion Sanguine Country: France Publications
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Detail Information
Publications
[Fetal and neonatal alloimmune thrombocytopenias]C Kaplan
Immunologie Plaquettaire, Institut National de la Transfusion Sanguine, 75739 Paris cedex 15, France
Transfus Clin Biol 16:214-7. 2009..Any difficulties in confirming the diagnosis should not delay the treatment. Since the first description of these conditions in the 1950's, significant progress has been made in laboratory diagnosis and management...
Neonatal alloimmune thrombocytopeniaCecile Kaplan
Platelet immunology, GIP INTS, Paris
Haematologica 93:805-7. 2008
Monoclonal platelet antigen capture assays (MAIPA) and reagents: a statementC Kaplan
INTS, Platelet Immunology Laboratory, Paris, France
Vox Sang 93:298-9. 2007..The assay performed with reagents labelled for 'research only' is acceptable as long as it is regularly evaluated by participation of laboratories in national or international workshops held with reference laboratories...
[Fetal/neonatal allo-immune thrombocytopenias: the unsolved questions]C Kaplan
Laboratoire d Immunologie Plaquettaire, INTS, 6, Paris, France
Transfus Clin Biol 12:131-4. 2005..Nevertheless there are unsolved questions, particularly concerning the mechanism of the maternal immunization, the laboratory difficulties for the identification of the alloantibodies, the absence of antenatal management standardization...
Anti-HPA-9bw (Maxa) fetomaternal alloimmunization, a clinically severe neonatal thrombocytopenia: difficulties in diagnosis and therapy and report on eight familiesCecile Kaplan
INTS, Platelet Immunology Unit, Paris, France
Transfusion 45:1799-803. 2005..In Caucasian persons, HPA-1a is the most frequently implicated antigen. During the past few years, FMAIT has been reported associated with rare or private antigens...
Foetal and neonatal alloimmune thrombocytopaeniaCecile Kaplan
Unité d Immunologie Plaquettaire, Institut National de Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015 Paris, France
Orphanet J Rare Dis 1:39. 2006..Due to the high rate of recurrence and increased severity of the foetal thrombocytopaenia in successive pregnancies, antenatal therapy should be offered. However, management of high-risk pregnancies is still a matter of discussion...
New mutations on platelet GPIIb in Sub-Saharan African populations revealed by genotyping discrepanciesL Halle
Institut National de la Transfusion Sanguine, Paris, France
Transfusion 48:1415-22. 2008....
Immune thrombocytopenia in the foetus and the newborn: diagnosis and therapyC Kaplan
Unité d Immunologie Plaquettaire, INTS, Paris, France
Transfus Clin Biol 8:311-4. 2001....
Predictive value of sequential maternal anti-HPA-1a antibody concentrations for the severity of fetal alloimmune thrombocytopeniaG Bertrand
INTS, Platelet Immunology Unit, Paris, France
J Thromb Haemost 4:628-37. 2006..However, though we observed a tendency toward a decrease in maternal antibody concentration after treatment, this finding does not allow us to draw any conclusions on the effectiveness of therapy...
Neonatal alloimmune thrombocytopenia: a 50-year storyC Kaplan
Platelet Immunology Laboratory, Institut National de la Transfusion Sanguine (INTS, 6 rue Alexandre Cabanel, 75015 Paris, France
Immunohematology 23:9-13. 2007
HPA polymorphism in sub-Saharan African populations: Beninese, Cameroonians, Congolese, and PygmiesL Halle
Institut National de la Transfusion Sanguine, Paris, France
Tissue Antigens 65:295-8. 2005....
[Genotyping applied to platelet immunology: when? How? Limits]G Bertrand
Laboratoire d Immunologie Plaquettaire, GIP INTS, 75015 Paris, France
Transfus Clin Biol 16:164-9. 2009..Consequently, it would be of interest to develop alternative technologies based on antigen/antibody interaction instead of DNA...
Immune thrombocytopenia in the fetus and neonate: diagnosis and therapyC Kaplan
Platelet Immunology Department, Institut National de la Transfusion Sanguine, Paris, France
Thromb Res 115:39-41. 2005
Alloimmune thrombocytopenia of the fetus and the newbornC Kaplan
Institut National de Transfusion Sanguine, Unité d Immunologie Plaquettaire, Paris, France
Blood Rev 16:69-72. 2002..Screening of pregnant women may become a public health issue only after antenatal therapy is more standardized...
Eleven human platelet systems studied in the Vietnamese and Ma'ohis Polynesian populationsL Halle
Institut National de la Transfusion Sanguine (INTS, Laboratoire d'Immunologie Plaquettaire, Paris, France
Tissue Antigens 63:34-40. 2004..Given HPA-3 gene frequency distribution fetomaternal incompatibility could occur more frequently with the risk of alloantibody production...
