Bertrand Hirel

Summary

Affiliation: Institut National de la Recherche Agronomique
Country: France

Publications

  1. ncbi request reprint Rubisco synthesis, turnover and degradation: some new thoughts on an old problem
    Bertrand Hirel
    Unité de Nutrition Azotée des Plantes, INRA, Versailles, France
    New Phytol 169:445-8. 2006
  2. ncbi request reprint An integrated "omics" approach to the characterization of maize (Zea mays L.) mutants deficient in the expression of two genes encoding cytosolic glutamine synthetase
    Nardjis Amiour
    Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique INRA, Centre de Versailles Grignon, Unité Mixte de Recherche 1318 INRA Agro ParisTech, Equipe de Recherche Labellisée, Centre National de la Recherche Scientifique 3559, RD10, F 78026 Versailles, Cedex, France
    BMC Genomics 15:1005. 2014
  3. pmc Resolving the role of plant glutamate dehydrogenase. I. In vivo real time nuclear magnetic resonance spectroscopy experiments
    Soraya Labboun
    Génie Enzymatique et Cellulaire, UMR CNRS 6022, UFR des Sciences, Universite de Picardie Jules Verne, 33, rue Saint Leu, 80039 Amiens Cedex, France
    Plant Cell Physiol 50:1761-73. 2009
  4. ncbi request reprint The challenge of improving nitrogen use efficiency in crop plants: towards a more central role for genetic variability and quantitative genetics within integrated approaches
    Bertrand Hirel
    Unité de Nutrition Azotée des Plantes, UR 511, INRA de Versailles, Route de St Cyr, F 78026 Versailles Cedex, France
    J Exp Bot 58:2369-87. 2007
  5. pmc Towards a better understanding of the genetic and physiological basis for nitrogen use efficiency in maize
    B Hirel
    Unité de Nutrition Azotée des Plantes, Institut National de la Recherche Agronomique, Route de St Cyr 78026, Versailles Cedex, France
    Plant Physiol 125:1258-70. 2001
  6. pmc Two cytosolic glutamine synthetase isoforms of maize are specifically involved in the control of grain production
    Antoine Martin
    Unité de Nutrition Azotée des Plantes UR511, Institut National de la Recherche Agronomique, F 78026 Versailles Cedex, France
    Plant Cell 18:3252-74. 2006
  7. ncbi request reprint Resolving the role of plant glutamate dehydrogenase: II. Physiological characterization of plants overexpressing the two enzyme subunits individually or simultaneously
    Thérèse Tercé-Laforgue
    Adaptation des Plantes à leur Environnement, Unité Mixte de Recherche 1318, Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique INRA, Centre de Versailles Grignon, RD 10, 78026 Versailles Cedex, France
    Plant Cell Physiol 54:1635-47. 2013
  8. pmc Glutamate dehydrogenase of tobacco is mainly induced in the cytosol of phloem companion cells when ammonia is provided either externally or released during photorespiration
    Thérèse Tercé-Laforgue
    Unité de Nutrition Azotée des Plantes, Institut National de la Recherche Agronomique, 78026 Versailles Cedex, France
    Plant Physiol 136:4308-17. 2004
  9. ncbi request reprint The use of metabolomics integrated with transcriptomic and proteomic studies for identifying key steps involved in the control of nitrogen metabolism in crops such as maize
    Nardjis Amiour
    Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique, Centre de Versailles Grignon, UR 511, Route de St Cyr, F 78026 Versailles Cedex, France
    J Exp Bot 63:5017-33. 2012
  10. ncbi request reprint Can genetic variability for nitrogen metabolism in the developing ear of maize be exploited to improve yield?
    Rafael A Cañas
    Adaptation des Plantes à leur Environnement, Unité Mixte de Recherche 1318, Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique INRA, Centre de Versailles Grignon, RD 10, F 78026 Versailles, France
    New Phytol 194:440-52. 2012

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Rubisco synthesis, turnover and degradation: some new thoughts on an old problem
    Bertrand Hirel
    Unité de Nutrition Azotée des Plantes, INRA, Versailles, France
    New Phytol 169:445-8. 2006
  2. ncbi request reprint An integrated "omics" approach to the characterization of maize (Zea mays L.) mutants deficient in the expression of two genes encoding cytosolic glutamine synthetase
    Nardjis Amiour
    Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique INRA, Centre de Versailles Grignon, Unité Mixte de Recherche 1318 INRA Agro ParisTech, Equipe de Recherche Labellisée, Centre National de la Recherche Scientifique 3559, RD10, F 78026 Versailles, Cedex, France
    BMC Genomics 15:1005. 2014
    ....
  3. pmc Resolving the role of plant glutamate dehydrogenase. I. In vivo real time nuclear magnetic resonance spectroscopy experiments
    Soraya Labboun
    Génie Enzymatique et Cellulaire, UMR CNRS 6022, UFR des Sciences, Universite de Picardie Jules Verne, 33, rue Saint Leu, 80039 Amiens Cedex, France
    Plant Cell Physiol 50:1761-73. 2009
    ..Thus, in vivo NMR spectroscopy appears to be an attractive technique to follow the flux of metabolites in both normal and genetically modified plants...
  4. ncbi request reprint The challenge of improving nitrogen use efficiency in crop plants: towards a more central role for genetic variability and quantitative genetics within integrated approaches
    Bertrand Hirel
    Unité de Nutrition Azotée des Plantes, UR 511, INRA de Versailles, Route de St Cyr, F 78026 Versailles Cedex, France
    J Exp Bot 58:2369-87. 2007
    ..Current knowledge and prospects for future agronomic development and application for breeding crops adapted to lower fertilizer input are explored, taking into account the world economic and environmental constraints in the next century...
  5. pmc Towards a better understanding of the genetic and physiological basis for nitrogen use efficiency in maize
    B Hirel
    Unité de Nutrition Azotée des Plantes, Institut National de la Recherche Agronomique, Route de St Cyr 78026, Versailles Cedex, France
    Plant Physiol 125:1258-70. 2001
    ....
  6. pmc Two cytosolic glutamine synthetase isoforms of maize are specifically involved in the control of grain production
    Antoine Martin
    Unité de Nutrition Azotée des Plantes UR511, Institut National de la Recherche Agronomique, F 78026 Versailles Cedex, France
    Plant Cell 18:3252-74. 2006
    ..The two GS1 isoenzymes play nonredundant roles with respect to their tissue-specific localization...
  7. ncbi request reprint Resolving the role of plant glutamate dehydrogenase: II. Physiological characterization of plants overexpressing the two enzyme subunits individually or simultaneously
    Thérèse Tercé-Laforgue
    Adaptation des Plantes à leur Environnement, Unité Mixte de Recherche 1318, Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique INRA, Centre de Versailles Grignon, RD 10, 78026 Versailles Cedex, France
    Plant Cell Physiol 54:1635-47. 2013
    ....
  8. pmc Glutamate dehydrogenase of tobacco is mainly induced in the cytosol of phloem companion cells when ammonia is provided either externally or released during photorespiration
    Thérèse Tercé-Laforgue
    Unité de Nutrition Azotée des Plantes, Institut National de la Recherche Agronomique, 78026 Versailles Cedex, France
    Plant Physiol 136:4308-17. 2004
    ....
  9. ncbi request reprint The use of metabolomics integrated with transcriptomic and proteomic studies for identifying key steps involved in the control of nitrogen metabolism in crops such as maize
    Nardjis Amiour
    Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique, Centre de Versailles Grignon, UR 511, Route de St Cyr, F 78026 Versailles Cedex, France
    J Exp Bot 63:5017-33. 2012
    ..The potential use of these 'omics' studies is discussed with a view to improve our understanding of whole plant nitrogen economics, which should have applications in breeding and agronomy...
  10. ncbi request reprint Can genetic variability for nitrogen metabolism in the developing ear of maize be exploited to improve yield?
    Rafael A Cañas
    Adaptation des Plantes à leur Environnement, Unité Mixte de Recherche 1318, Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique INRA, Centre de Versailles Grignon, RD 10, F 78026 Versailles, France
    New Phytol 194:440-52. 2012
    ..Such an approach leads to the identification of possible new regulatory metabolic and developmental networks specific to the ear that may be of major importance for maize productivity...
  11. ncbi request reprint An integrated statistical analysis of the genetic variability of nitrogen metabolism in the ear of three maize inbred lines (Zea mays L.)
    Rafael A Cañas
    Adaptation des Plantes à leur Environnement, Unité de Recherche 511, Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique, Centre de Versailles Grignon, Route de Saint Cyr, F 78026 Versailles Cedex, France
    J Exp Bot 62:2309-18. 2011
    ....
  12. ncbi request reprint Nitrogen metabolism in the developing ear of maize (Zea mays): analysis of two lines contrasting in their mode of nitrogen management
    Rafael A Cañas
    Unité de Nutrition Azotée des Plantes, Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique, F 78026 Versailles Cedex, France
    New Phytol 184:340-52. 2009
    ..Thus, in maize there is genetic and environmental control of N metabolism not only in vegetative source organs but also in reproductive sink organs...
  13. ncbi request reprint Analysis of amino acid metabolism in the ear of maize mutants deficient in two cytosolic glutamine synthetase isoenzymes highlights the importance of asparagine for nitrogen translocation within sink organs
    Rafael A Cañas
    Unité de Nutrition Azotée des Plantes, Unité de Recherche 511, Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique, Centre de Versailles Grignon, Versailles Cedex, France
    Plant Biotechnol J 8:966-78. 2010
    ..The two genes ZmAS3 and ZmAS4 are likely to play an important role during this process...
  14. ncbi request reprint Cellular and subcellular localisation of glutamine synthetase and glutamate dehydrogenase in grapes gives new insights on the regulation of carbon and nitrogen metabolism
    Virginie Paczek
    Unité de Nutrition Azotée des Plantes, INRA de Versailles, Route de Saint Cyr, 78026 Versailles Cedex, France
    Planta 216:245-54. 2002
    ....
  15. pmc Does lowering glutamine synthetase activity in nodules modify nitrogen metabolism and growth of Lotus japonicus?
    Judith Harrison
    Laboratoire Nutrition Azotée des Plantes, Institut National de la Recherche Agronomique, Route de St Cyr, 78280 Versailles cedex, France
    Plant Physiol 133:253-62. 2003
    ..japonicus. Whether these alternative metabolic pathways are important in the control of plant biomass production still remains to be fully elucidated...
  16. ncbi request reprint Nitrogen management and senescence in two maize hybrids differing in the persistence of leaf greenness: agronomic, physiological and molecular aspects
    Antoine Martin
    Unité de Nutrition Azotée des Plantes, INRA, R D 10, 78026 Versailles Cedex, France
    New Phytol 167:483-92. 2005
    ..The possibility of improving N metabolic efficiency in the latest maize hybrids is discussed...
  17. ncbi request reprint Modelling postsilking nitrogen fluxes in maize (Zea mays) using 15N-labelling field experiments
    André Gallais
    Station de Génétique Végétale, INRA UPS INAPG CNRS, Ferme du Moulon, 91190 Gif Yvette, France
    New Phytol 172:696-707. 2006
    ....
  18. ncbi request reprint Glutamine and alpha-ketoglutarate are metabolite signals involved in nitrate reductase gene transcription in untransformed and transformed tobacco plants deficient in ferredoxin-glutamine-alpha-ketoglutarate aminotransferase
    S Ferrario-Mery
    Unité de Nutrition Azotée des Plantes, INRA de Versailles, France
    Planta 213:265-71. 2001
    ....
  19. ncbi request reprint An approach to the genetics of nitrogen use efficiency in maize
    A Gallais
    Station de Génétique Végétale, INRA UPS INAPG, Ferme du Moulon, 91190 Gif Yvette, France
    J Exp Bot 55:295-306. 2004
    ..This may have a physiological meaning. The GS locus on chromosome 5 appears to be a good candidate gene which can, at least partially, explain the variation in nitrogen use efficiency...
  20. ncbi request reprint Characterization of the sink/source transition in tobacco ( Nicotiana tabacum L.) shoots in relation to nitrogen management and leaf senescence
    C Masclaux
    Unité de Nutrition Azotée des Plantes, INRA, Centre de Versailles, France
    Planta 211:510-8. 2000
    ..The role of the newly induced enzymes and the nature of the potential metabolic and developmental signals involved in the regulation of their expression during leaf senescence are discussed...
  21. ncbi request reprint A novel HMG A-like protein binds differentially to the AT-rich regions located in the far distal and proximal parts of a soybean glutamine synthetase gene (GS15) promoter
    Michèle Reisdorf-Cren
    Laboratoire de la Nutrition Azotée des Plantes, INRA, Centre de Versailles, Route de Saint Cyr, F 78026 Versailles Cedex, France
    Plant Cell Physiol 43:1006-16. 2002
    ..This result suggests that AT-1SNBP may be an architectural protein involved in maintaining the spatial conformation of the GS15 promoter, thus facilitating the interaction between the distal and proximal regulatory elements...
  22. ncbi request reprint Forcing expression of a soybean root glutamine synthetase gene in tobacco leaves induces a native gene encoding cytosolic enzyme
    B Hirel
    Laboratoire du Métabolisme et de la Nutrition des Plantes, C N R A, Versailles, France
    Plant Mol Biol 20:207-18. 1992
    ..The latter is normally expressed only in the root tissue of tobacco. This phenomenon may suggest a hitherto uncharacterized metabolic control on the expression of certain genes in plants...
  23. ncbi request reprint Assessing the metabolic impact of nitrogen availability using a compartmentalized maize leaf genome-scale model
    MARGARET SIMONS
    Departments of Chemical Engineering M S, R S, C D M and Bioinformatics and Genomics, Huck Institutes of the Life Sciences A K, Pennsylvania State University, University Park, Pennsylvania 16802 Institut Jean Pierre Bourgin, Institut National de la Recherche Agronomique, Centre de Versailles Grignon, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique Agro ParisTech, Equipe de Recherce Labellisée, Centre National de la Recherche Scientifique 3559, F 78026 Versailles Cedex, France N A, L G, G C, M M, Z L, G M, B H andLancaster Environment Centre, Lancaster University, Lancaster LA1 4YQ, United Kingdom P J L
    Plant Physiol 166:1659-74. 2014
    ..Model-predicted results achieved 90% accuracy when comparing the wild type grown under an N-complete condition with the wild type grown under an N-deficient condition. ..
  24. ncbi request reprint Photorespiration-dependent increases in phospho enolpyruvate carboxylase, isocitrate dehydrogenase and glutamate dehydrogenase in transformed tobacco plants deficient in ferredoxin-dependent glutamine-alpha-ketoglutarate aminotransferase
    Sylvie Ferrario-Mery
    Unité de Nutrition Azotée des Plantes, INRA de Versailles, Route de Saint Cyr, 78026 Versailles Cedex, France
    Planta 214:877-86. 2002
    ..In addition, we provide the first demonstration of a compensatory role for NAD(H)-GDH in stabilising the leaf glutamic acid pool when Fd-GOGAT becomes limiting...
  25. ncbi request reprint Gene expression, cellular localisation and function of glutamine synthetase isozymes in wheat (Triticum aestivum L.)
    Stéphanie M Bernard
    Plant Science Department, Centre for Crop Genetic Improvement, Rothamsted Research, Harpenden, Hertfordshire, UK
    Plant Mol Biol 67:89-105. 2008
    ..Use of this genetic variation should inform future efforts to modulate this enzyme for pre-breeding efforts to improve nitrogen use in wheat...
  26. ncbi request reprint Control of the synthesis and subcellular targeting of the two GDH genes products in leaves and stems of Nicotiana plumbaginifolia and Arabidopsis thaliana
    Jean Xavier Fontaine
    Laboratoire d Androgénèse et Biotechnologie Végétale, Universite de Picardie Jules Verne, Amiens, France
    Plant Cell Physiol 47:410-8. 2006
    ..These results are discussed in relation to the possible signalling and/or physiological function of the enzyme which appears to be coordinated in leaves and stems...
  27. ncbi request reprint Combined agronomic and physiological aspects of nitrogen management in wheat highlight a central role for glutamine synthetase
    Thomas Kichey
    Laboratoire d Androgénèse et Biotechnologie Végétale, Universite de Picardie Jules Verne, 33 rue Saint Leu, F 80039 Amiens Cedex, France
    New Phytol 169:265-78. 2006
    ..The use of a marker such as GS activity to predict the N status of wheat, as a function of both plant development and N availability, is discussed with the aim of selecting wheat genotypes with better N-use efficiency...
  28. ncbi request reprint Changes in the cellular and subcellular localization of glutamine synthetase and glutamate dehydrogenase during flag leaf senescence in wheat (Triticum aestivum L.)
    Thomas Kichey
    Laboratoire d Androgénèse et Biotechnologie Végétale, Universite de Picardie Jules Verne, 33, rue Saint Leu, 80039 Amiens Cedex, France
    Plant Cell Physiol 46:964-74. 2005
    ....
  29. ncbi request reprint Overexpression of a soybean cytosolic glutamine synthetase gene linked to organ-specific promoters in pea plants grown in different concentrations of nitrate
    Houman Fei
    Department of Plant Science, University of Manitoba, Winnipeg, MB R3T 2N2, Canada
    Planta 216:467-74. 2003
    ....
  30. pmc Genetic and physiological analysis of germination efficiency in maize in relation to nitrogen metabolism reveals the importance of cytosolic glutamine synthetase
    Anis M Limami
    Unité Mixte de Recherche Physiologie Moléculaire des Semences, Universite d Angers, 2 Boulevard Lavoisier, 49045 Angers Cedex, France
    Plant Physiol 130:1860-70. 2002
    ....
  31. ncbi request reprint Effects of the overexpression of a soybean cytosolic glutamine synthetase gene (GS15) linked to organ-specific promoters on growth and nitrogen accumulation of pea plants supplied with ammonium
    Houman Fei
    Department of Plant Science, University of Manitoba, Winnipeg, MB, Canada R3T 2N2
    Plant Physiol Biochem 44:543-50. 2006
    ....