Research Topics
| Jean Paul GuthmannSummaryAffiliation: Institut de Veille Sanitaire Country: France Publications
| Collaborators
|
Detail Information
Publications
Vaccination coverage of health care personnel working in health care facilities in France: results of a national survey, 2009Jean Paul Guthmann
InVS Institut de Veille Sanitaire French Institute for Public Health Surveillance, 12 Rue du Val d Osne, 94415 Saint Maurice Cedex, France
Vaccine 30:4648-54. 2012..01). HCP are overall well covered by compulsory vaccinations, whereas VC for non-compulsory vaccinations is very insufficient. The vaccination policy regarding these latter vaccinations should be reinforced in France...- Influenza vaccination coverage one year after the A(H1N1) influenza pandemic, France, 2010-2011Jean Paul Guthmann
Departement des Maladies Infectieuses, Institut de Veille Sanitaire, Saint Maurice, France
Vaccine 30:995-7. 2012..Our results do not suggest that the controversies related to the pandemic vaccination campaign of 2009-2010 have had a negative impact on subsequent seasonal influenza vaccination coverage... 
The relationship between the haemoglobin concentration and the haematocrit in Plasmodium falciparum malariaSue J Lee
Mahidol Oxford Tropical Medicine Research Unit MORU, Mahidol University, Faculty of Tropical Medicine, 3rd Floor, 60th Anniversary Chalermprakiat Building, 420 6 Ratchawithi Rd, Ratchathewi District, Bangkok 10400, Thailand
Malar J 7:149. 2008..Anaemia is assessed either by measurement of the haematocrit or the haemoglobin concentration. For comparisons across studies, it is often necessary to derive one measure from the other...- Efficacy of artesunate-amodiaquine for treating uncomplicated falciparum malaria in sub-Saharan Africa: a multi-centre analysisJulien Zwang
Shoklo Malaria Research Unit, Mae Sot, Thailand
Malar J 8:203. 2009..It was necessary to evaluate the efficacy of ACT, recently adopted by the World Health Organization (WHO) and deployed over 80 countries, in order to make an evidence-based drug policy... - Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African childrenElizabeth A Ashley
Epicentre, Paris, France
Malar J 7:154. 2008..Use of different methods for assessing the efficacy of artemisinin-based combination antimalarial treatments (ACTs) will result in different estimates being reported, with implications for changes in treatment policy... - Varying efficacy of artesunate+amodiaquine and artesunate+sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in the Democratic Republic of Congo: a report of two in-vivo studiesMaryline Bonnet
Epicentre, Geneva 21, Switzerland
Malar J 8:192. 2009..Very few data on anti-malarial efficacy are available from the Democratic Republic of Congo (DRC). DRC changed its anti-malarial treatment policy to amodiaquine (AQ) and artesunate (AS) in 2005... - Community coverage of an antimalarial combination of artesunate and amodiaquine in Makamba Province, Burundi, nine months after its introductionSibylle Gerstl
Epicentre, Paris, France
Malar J 6:94. 2007..Nine months after its implementation a study was carried out to assess whether children below five years of age with uncomplicated malaria were actually receiving AS+AQ... - [Factors associated with tetanus vaccination coverage in adults in France and with knowledge of vaccination status]J P Guthmann
Unité des maladies à prévention vaccinale, Departement des Maladies Infectieuses, Institut de Veille Sanitaire, 12, rue du Val d Osne, 94415 Saint Maurice Cedex, France
Med Mal Infect 40:560-7. 2010..The latest national figures showed that only 62% of adults were up-to-date for this vaccination. We tried to determine the factors associated with vaccination coverage and with knowledge of vaccination status... - Death rates from malaria epidemics, Burundi and EthiopiaJean Paul Guthmann
Institut de Veille Sanitaire, Saint Maurice, France
Emerg Infect Dis 13:140-3. 2007..Deaths likely from malaria ranged from 1,000 to 8,900, depending on site, and accounted for 52% to 78% of total deaths. Earlier detection of malaria and better case management are needed... - [BCG vaccination coverage in children born after the end of compulsory BCG vaccination and followed in maternal and child health clinics in France: a national survey 2009]J P Guthmann
Unité des maladies à prévention vaccinale, Departement des Maladies Infectieuses, institut de veille sanitaire InVS, 12, rue du Val d Osne, 94415 Saint Maurice Cedex, France
Arch Pediatr 17:1281-7. 2010..We measured BCG vaccination coverage (VC) in children for whom BCG is recommended, who were born after the end of compulsory BCG vaccination and are usually followed at Maternal and Child Health Clinics (MCHC)... - [Clinical research and humanitarian work: the role of Médecins sans Frontières in the fight against malaria]Jean Paul Guthmann
Unité Maladies à Prévention Vaccinale, Departement de Maladies Infectieuses, Institut de Veille Sanitaire, 12, rue du Val d Osne, 94415 Saint Maurice, France
Med Sci (Paris) 25:301-6. 2009.... - [BCG vaccine coverage in private medical practice: First data in children below two years old, seven months after the end of compulsory vaccination in France]J P Guthmann
Unité des maladies à prévention vaccinale, Departement des Maladies Infectieuses, institut de veille sanitaire InVS, 12, rue du Val d Osne, 94415 Saint Maurice Cedex, France
Arch Pediatr 16:489-95. 2009.... - Influenza vaccination coverage against seasonal and pandemic influenza and their determinants in France: a cross-sectional surveySophie Vaux
Department of Infectious Diseases, Institut de Veille Sanitaire, French Institute for Public Health Surveillance, Saint Maurice, France
BMC Public Health 11:30. 2011..Groups of people were defined and prioritised for vaccination... - Influenza vaccination coverage of healthcare workers and residents and their determinants in nursing homes for elderly people in France: a cross-sectional surveySophie Vaux
Department of Infectious Diseases, Institut de Veille Sanitaire InVS French Institute for Public Health Surveillance, Saint Maurice, France
BMC Public Health 10:159. 2010..Vaccination of residents and healthcare workers (HCWs) is the main strategy for prevention. Despite recommendations, influenza vaccination coverage among HCWs remains generally low... - Population and risk group uptake of H1N1 influenza vaccine in mainland France 2009-2010: results of a national vaccination campaignAngie Bone
Institut de veille sanitaire French Institute for Public Health Surveillance, 12 Rue du Val d Osne, 94415 Saint Maurice Cedex, France
Vaccine 28:8157-61. 2010..Vaccine uptake in pregnant women was 22.7%. These low uptakes may reflect controversies around the vaccine and vaccination policy and have important implications for future pandemic vaccination strategies... - Incidence of H1N1 2009 virus infection through the analysis of paired plasma specimens among blood donors, FranceAngie Bone
Institut de Veille Sanitaire, St Maurice, France
PLoS ONE 7:e33056. 2012..It provides the basis for estimating the future impact of influenza A (H1N1pdm09) and implementing appropriate prevention and response strategies... - Malaria epidemics and interventions, Kenya, Burundi, southern Sudan, and Ethiopia, 1999-2004Francesco Checchi
Department of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, London, United Kingdom
Emerg Infect Dis 12:1477-85. 2006.... 
Molecular genotyping in a malaria treatment trial in Uganda - unexpected high rate of new infections within 2 weeks after treatmentKefas Mugittu
Ifakara Health Research and Development Centre, Ifakara, Tanzania
Trop Med Int Health 12:219-23. 2007..2%)] and 14 [24/51 (47.1%)]. These results impact significantly on resistance monitoring and point to the value of genotyping all recurrent infections in antimalarial trials...- Evaluation of three rapid tests for diagnosis of P. falciparum and P. vivax malaria in ColombiaIngrid van den Broek
Médecins sans Frontières MSF, London, UK
Am J Trop Med Hyg 75:1209-15. 2006..vivax cases as more acceptable than missing some cases of P. falciparum, we recommend careful implementation of NOW-malaria-ICT in areas where microscopy is lacking. The price is however still a constraint... - Efficacy of three artemisinin combination therapies for the treatment of uncomplicated Plasmodium falciparum malaria in the Republic of CongoIngrid van den Broek
Medecins Sans Frontieres, London, UK
Malar J 5:113. 2006..Presented here are the results of a comparative trial on the efficacy of three artemisinin-based combinations conducted from May to October 2004, in Pool Province, Republic of Congo... - Adherence to the combination of sulphadoxine-pyrimethamine and artesunate in the Maheba refugee settlement, ZambiaEvelyn Depoortere
Epicentre, Paris, France
Trop Med Int Health 9:62-7. 2004..For these treatment regimens to remain efficacious on a long-term basis, specific and locally adapted strategies need to be implemented to ensure completion of the treatment... - Antimalarial efficacy of sulfadoxine-pyrimethamine, amodiaquine and a combination of chloroquine plus sulfadoxine-pyrimethamine in Bundi Bugyo, western UgandaFrancesco Checchi
Epicentre, Paris, France
Trop Med Int Health 9:445-50. 2004..Our study also confirms previous findings that resistance is considerably underestimated by 14-day follow-ups. Antimalarial policy decisions should therefore be based on 28-day studies, with PCR adjustment to distinguish re-infections... - Artesunate and sulfadoxine-pyrimethamine combinations for the treatment of uncomplicated Plasmodium falciparum malaria in Uganda: a randomized, double-blind, placebo-controlled trialGerardo Priotto
Epicentre, 8 rue Saint Sabin, 75011 Paris, France
Trans R Soc Trop Med Hyg 97:325-30. 2003..Treatment efficacy improved with SPAS3 but the cure rate at day 28 was modest. The combinations were well tolerated and safe. In areas where SP resistance is prevalent other combinations should be considered... - Efficacy of chloroquine, sulphadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria in Kajo Keji county, SudanElisa Stivanello
Medecins Sans Frontieres, Geneva, Switzerland
Trop Med Int Health 9:975-80. 2004..We recommend a combination of artemether and lumefantrine as first-line treatment for uncomplicated P. falciparum malaria cases in Kajo Keji county... - In vivo assessment of drug efficacy against Plasmodium falciparum malaria: duration of follow-upKasia Stepniewska
Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Rd, Bangkok 10400, Thailand
Antimicrob Agents Chemother 48:4271-80. 2004..94) or if the entomological inoculation rate was known. In the assessment of drug efficacy against falciparum malaria, 28 days should be the minimum period of follow-up... - Adherence to a six-dose regimen of artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in UgandaCarole Fogg
Epicentre, Paris, France
Am J Trop Med Hyg 71:525-30. 2004..The high adherence to artemether-lumefantrine found in our study suggest that this drug is likely to be very effective in Mbarara provided that patients receive clear dosage explanations... - Efficacy and effectiveness of the combination of sulfadoxine/pyrimethamine and a 3-day course of artesunate for the treatment of uncomplicated falciparum malaria in a refugee settlement in ZambiaEvelyn Depoortere
Epicentre, 8 rue Saint Sabin, 75011 Paris, France
Trop Med Int Health 10:139-45. 2005..When implementing new malaria treatment policies, serious investment in ensuring patient adherence is essential to ascertain the effectiveness of the new treatment schedules... - Supervised versus unsupervised intake of six-dose artemether-lumefantrine for treatment of acute, uncomplicated Plasmodium falciparum malaria in Mbarara, Uganda: a randomised trialPatrice Piola
Epicentre, 8 rue Saint Sabin, 75011 Paris, France
Lancet 365:1467-73. 2005.... - Antimalarial efficacy of chloroquine, amodiaquine, sulfadoxine-pyrimethamine, and the combinations of amodiaquine + artesunate and sulfadoxine-pyrimethamine + artesunate in Huambo and Bie provinces, central AngolaJean Paul Guthmann
Epicentre, 42 bis, Boulevard Richard Lenoir, 75011 Paris, France
Trans R Soc Trop Med Hyg 99:485-92. 2005..We recommend the use of AQ with AS, though this combination might not have a long useful therapeutic life because of AQ resistance... - Efficacy of chloroquine, sulfadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria among children under five in Bongor and Koumra, ChadFrancesco Grandesso
Epicentre, 8 rue Saint Sabin, 75011 Paris, France
Trans R Soc Trop Med Hyg 100:419-26. 2006..Nevertheless, the efficacy of this combination should be evaluated and the change carefully prepared, implemented and monitored... - Operational response to malaria epidemics: are rapid diagnostic tests cost-effective?Estelle Rolland
Epicentre, Paris, France
Trop Med Int Health 11:398-408. 2006..To compare the cost-effectiveness of malaria treatment based on presumptive diagnosis with that of malaria treatment based on rapid diagnostic tests (RDTs)... - High mortality associated with an outbreak of hepatitis E among displaced persons in Darfur, SudanDelia Boccia
European Programme for Intervention Epidemiology Training, Stockholm, Sweden
Clin Infect Dis 42:1679-84. 2006..2%). CONCLUSIONS: This large epidemic of HEV infection illustrates the dramatic impact of this disease on pregnant women. Timely interventions and a vaccine are urgently needed to prevent mortality in this special group... - A large outbreak of hepatitis E among a displaced population in Darfur, Sudan, 2004: the role of water treatment methodsJean Paul Guthmann
Epicentre, Paris, France
Clin Infect Dis 42:1685-91. 2006..The conflict in Darfur, Sudan, was responsible for the displacement of 1.8 million civilians. We investigated a large outbreak of hepatitis E virus (HEV) infection in Mornay camp (78,800 inhabitants) in western Darfur... - Efficacy of chloroquine and sulfadoxine/pyrimethamine for the treatment of uncomplicated falciparum malaria in Koumantou, MaliXavier de Radiguès
Epicentre, 42 bis, Boulevard Richard Lenoir, 75011 Paris, France
Trans R Soc Trop Med Hyg 100:1013-8. 2006..The use of SP in monotherapy is likely to compromise its efficacy. We recommend the use of artemisinin-based combination therapy as first-line treatment for uncomplicated Plasmodium falciparum malaria in Koumantou... - Low efficacy of the combination artesunate plus amodiaquine for uncomplicated falciparum malaria among children under 5 years in Kailahun, Sierra LeoneFrancesco Grandesso
Epicentre, Paris, France
Trop Med Int Health 11:1017-21. 2006..In Kailahun a more efficacious combination might be necessary in the future. The efficacy of AS + AQ needs to be monitored in Kailahun and in the other regions of Sierra Leone... - High efficacy of two artemisinin-based combinations (artesunate + amodiaquine and artemether + lumefantrine) in Caala, Central AngolaJean Paul Guthmann
Epicentre, Paris, France Médecins Sans Frontières, Paris, France
Am J Trop Med Hyg 75:143-5. 2006..1% to 15.9%). Our findings are in favor of a high efficacy of both combinations in Caala. Now that Coartem has been chosen as the new first-line anti-malarial, the challenge is to insure that this drug is available and adequately used... - Supervised versus unsupervised antimalarial treatment with six-dose artemether-lumefantrine: pharmacokinetic and dosage-related findings from a clinical trial in UgandaFrancesco Checchi
Epicentre, Paris, France
Malar J 5:59. 2006.... - A selective sweep driven by pyrimethamine treatment in southeast asian malaria parasitesShalini Nair
Southwest Foundation for Biomedical Research, San Antonio, Texas, USA
Mol Biol Evol 20:1526-36. 2003....