Research Topics
Genomes and Genes | B GasnierSummaryAffiliation: Institut de Biologie Physico-Chimique Country: France Publications
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Publications
The loading of neurotransmitters into synaptic vesiclesB Gasnier
CNRS UPR 1929, Institut de Biologie Physico Chimique, Paris, France
Biochimie 82:327-37. 2000....
The SLC32 transporter, a key protein for the synaptic release of inhibitory amino acidsBruno Gasnier
Institut de Biologie Physico Chimique, Centre National de la Recherche Scientifique UPR 1929, 13 rue Pierre et Marie Curie, 75005, Paris, France
Pflugers Arch 447:756-9. 2004....
Inactivation of the catecholamine transporter during the preparation of chromaffin granule membrane 'ghosts'B Gasnier
Unité de Neurobiologie Physico Chimique, Institut de Biologie Physico Chimique, Paris, France
FEBS Lett 222:215-9. 1987..The reserpine to dihydrotetrabenazine binding ratio (10-25%) is an estimate of the proportion of correctly resealed vesicles...
Hydrophobicity of the tetrabenazine-binding site of the chromaffin granule monoamine transporterD Scherman
Institut de Biologie Physico Chimique, Paris, France
Mol Pharmacol 33:72-7. 1988..Reserpine, haloperidol, and chlorpromazine have much lower intrinsic affinity for the TBZ-binding site...
The vesicular monoamine transporter: from chromaffin granule to brainJ P Henry
Centre National de la Recherche Scientifique, ERS 575, Institute de Biologie Physico Chimique, Paris, France
Neurochem Int 32:227-46. 1998..The possibility of regulations at the vesicular transporter level and of their effect on the quantum size has to be investigated. The vesicular monoamine transporter is also an important target for brain imaging...
Cloning of a functional vesicular GABA and glycine transporter by screening of genome databasesC Sagne
CNRS ERS 575, Institut de Biologie Physico Chimique, Paris, France
FEBS Lett 417:177-83. 1997..These observations, consistent with previous data on GABA and glycine uptake by synaptic vesicles, demonstrate that the mouse clone encodes a vesicular inhibitory amino acid transporter...
Photoaffinity labeling of the monoamine transporter of bovine chromaffin granules and other monoamine storage vesicles using 7-azido-8-[125I]iodoketanserinM F Isambert
Institut de Biologie Physico Chimique, Paris, France
Biochemistry 28:2265-70. 1989..Therefore, this molecule appears to be an excellent probe to label the monoamine transporter of different amine storage vesicles even without purification...
Molecular physiology and pathophysiology of lysosomal membrane transportersC Sagne
Institut de Biologie Physico Chimique, Centre National de la Recherche Scientifique, Universite Paris 7 Denis Diderot, Paris, France
J Inherit Metab Dis 31:258-66. 2008....
Expression and lysosomal targeting of CLN7, a major facilitator superfamily transporter associated with variant late-infantile neuronal ceroid lipofuscinosisA Sharifi
Institut de Biologie Physico Chimique, Universite Paris Descartes, Centre National de la Recherche Scientifique, UMR 8192, Institut de Biologie Physico Chimique, 13 rue P et M Curie, Paris, France
Hum Mol Genet 19:4497-514. 2010..Overall, these data highlight lysosomes as the primary site of action for CLN7, and suggest that the pathophysiology underpinning CLN7-associated vLINCL is a cell-autonomous process...
Expression and regulation of the bovine vesicular monoamine transporter geneE Krejci
Laboratoire de Neurobiologie, CNRS Unité Associée 295, Ecole Normale Superieure, Paris, France
FEBS Lett 335:27-32. 1993....
Postnatal maturation of Na+, K+, 2Cl- cotransporter expression and inhibitory synaptogenesis in the rat hippocampus: an immunocytochemical analysisSerge Marty
INSERM U106, Hopital de la Salpetriere, 47 Boulevard de l Hopital, 75013 Paris, France
Eur J Neurosci 15:233-45. 2002....
Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retinaAbdeljalil Jellali
Laboratoire de Physiopathologie Cellulaire et Moleculaire de la Retine, INSERM EMI 99 18, Universite Louis Pasteur, 1 Place de l Hopital, 67091 Strasbourg Cedex, France
J Comp Neurol 449:76-87. 2002..VIAAT localization in mouse and human horizontal cells further support the role of inhibitory transmitters in lateral inhibition at the photoreceptor terminals...
The SLC36 family: proton-coupled transporters for the absorption of selected amino acids from extracellular and intracellular proteolysisMichael Boll
Molecular Nutrition Unit, Institute of Nutritional Sciences, Technical University of Munich, Hochfeldweg 2, 85350, Freising Weihenstephan, Germany
Pflugers Arch 447:776-9. 2004..SLC36 transporters are related distantly to other proton-coupled amino acid transporters, such as the vesicular neurotransmitter transporter VIAAT/VGAT (SLC32) and system N transporters (SLC38 family)...
Molecular pathogenesis of cystinosis: effect of CTNS mutations on the transport activity and subcellular localization of cystinosinVasiliki Kalatzis
Inserm U574, Hopital Necker Enfants Malades, Paris, France
Hum Mol Genet 13:1361-71. 2004..Thus the transport assay could be used as a prognostic tool when novel mutations are identified...
The transporters GlyT2 and VIAAT cooperate to determine the vesicular glycinergic phenotypeKarin R Aubrey
Laboratoire de Neurobiologie, Centre National de la Recherche Scientifique, Ecole Normale Superieure, 75005 Paris, France
J Neurosci 27:6273-81. 2007..Together, these results suggest that an increased cytosolic availability of glycine in VIAAT-containing terminals was crucial for the emergence of glycinergic transmission in vertebrates...
