Research Topics
Genomes and Genes | Vincent GalySummaryAffiliation: Institut Pasteur Country: France Publications
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Detail Information
Publications
A role for gp210 in mitotic nuclear-envelope breakdownVincent Galy
EMBL, Meyerhofstrasse 1, 69117 Heidelberg, Germany
J Cell Sci 121:317-28. 2008..In summary, we show that gp210 is important for efficient NPC disassembly and NEBD and suggest that phosphorylation of gp210 is an early event in NEBD that is required for lamin disassembly and other aspects of NEBD...
MEL-28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assemblyCerstin Franz
European Molecular Biology Laboratory, Meyerhofstrasse 1, Heidelberg 69117, Germany
EMBO Rep 8:165-72. 2007..We suggest that MEL-28 acts as a seeding point for NPC assembly...
Caenorhabditis elegans nucleoporins Nup93 and Nup205 determine the limit of nuclear pore complex size exclusion in vivoVincent Galy
European Molecular Biology Laboratory, 69117 Heidelberg, Germany
Mol Biol Cell 14:5104-15. 2003..Thus, the contribution to NPC structure of Nup93 and Nup205 is essential for establishment of normal NPC function and for cell viability...
MEL-28, a novel nuclear-envelope and kinetochore protein essential for zygotic nuclear-envelope assembly in C. elegansVincent Galy
European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
Curr Biol 16:1748-56. 2006..We show that MEL-28 is an early-assembling, stable NE component required for all aspects of NE assembly...
EhPAK, a member of the p21-activated kinase family, is involved in the control of Entamoeba histolytica migration and phagocytosisElisabeth Labruyère
Unité de Biologie Cellulaire du Parasitisme, INSERM U389, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
J Cell Sci 116:61-71. 2003..Taking together, the results suggest strongly that EhPAK is a key regulatory element in polarity, motility and phagocytosis of E. histolytica...
Ran GTPase cycle and importins alpha and beta are essential for spindle formation and nuclear envelope assembly in living Caenorhabditis elegans embryosPeter Askjaer
European Molecular Biology Laboratory, 69117 Heidelberg, Germany
Mol Biol Cell 13:4355-70. 2002..Finally, we have demonstrated that both IMA-2 and IMB-1, the homologues of vertebrate importin alpha and beta, are essential for both spindle assembly and nuclear formation in early embryos...
The conserved Nup107-160 complex is critical for nuclear pore complex assemblyTobias C Walther
EMBL, Meyerhofstrasse 1, 69117 Heidelberg, Germany
Cell 113:195-206. 2003..Depletion also prevented association of FG-repeat nucleoporins with chromatin. We propose a stepwise model in which postmitotic NPC assembly initiates on chromatin via early recruitment of the Nup107-160 complex...
The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functionsMichela Zuccolo
Centre de Recherche, UMR 144 CNRS, Institut Curie, 26 Rue d Ulm, 75248 Paris Cedex 05, France
EMBO J 26:1853-64. 2007..Together, our data thus provide the first molecular clues underlying the function of the human Nup107-160 complex at kinetochores...
Caenorhabditis elegans BAF-1 and its kinase VRK-1 participate directly in post-mitotic nuclear envelope assemblyMatyas Gorjanacz
European Molecular Biology Laboratory, Heidelberg, Germany
EMBO J 26:132-43. 2007..We propose that phosphorylation of BAF by VRK plays an essential regulatory role in the association of BAF with chromatin and nuclear membrane proteins during NE formation...
The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cellsJörg Mansfeld
Institute of Biochemistry, ETH Zurich, CH 8093 Zurich, Switzerland
Mol Cell 22:93-103. 2006..Importantly, NDC1 interacts with Nup53 in vitro. This suggests that NDC1 function involves forming a link between the NE membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane...
Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1Vincent Galy
Unité de Biologie Cellulaire du Noyau, CNRS URA 2582, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
Cell 116:63-73. 2004..We propose that at this confined site the perinuclear Mlp1 implements a quality control step prior to export, physically retaining faulty pre-mRNAs...
Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in yeastFrank Feuerbach
Laboratoire de Biologie Cellulaire du Noyau, CNRS URA1773, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris Cedex 15, France
Nat Cell Biol 4:214-21. 2002..Our data support a model in which domains of enriched transcriptional regulators allow genes to determine transcriptional states by spatial positioning...
