Emmanuel Farge


Affiliation: Institut Curie
Country: France


  1. Farge E. Mechanical induction of Twist in the Drosophila foregut/stomodeal primordium. Curr Biol. 2003;13:1365-77 pubmed
    ..I propose that anterior-gut formation is mechanically induced by the movement of germ-band extension through the induction of Twist expression in stomodeal cells. ..
  2. Fernandez Sanchez M, Brunet T, Röper J, Farge E. Mechanotransduction's impact on animal development, evolution, and tumorigenesis. Annu Rev Cell Dev Biol. 2015;31:373-97 pubmed publisher
    ..In adult animal tissues, permanent stiffness and tissue growth pressure contribute to tumorigenesis and appear to reactivate such conserved embryonic mechanosensitive pathways. ..
  3. Merle T, Farge E. Trans-scale mechanotransductive cascade of biochemical and biomechanical patterning in embryonic development: the light side of the force. Curr Opin Cell Biol. 2018;55:111-118 pubmed publisher
  4. Broders Bondon F, Nguyen Ho Bouldoires T, Fernandez Sanchez M, Farge E. Mechanotransduction in tumor progression: The dark side of the force. J Cell Biol. 2018;217:1571-1587 pubmed publisher
    ..Understanding these mechanisms will be important for the development of innovative treatments to target such mechanical anomalies in cancer. ..