Dominique M Elias

Summary

Affiliation: Institut Gustave Roussy
Country: France

Publications

  1. ncbi request reprint Liver resection (and associated extrahepatic resections) for metastatic well-differentiated endocrine tumors: a 15-year single center prospective study
    Dominique Elias
    Department of Surgical Oncology, Comprehensive Cancer Center, Institut Gustave Roussy, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Surgery 133:375-82. 2003
  2. doi request reprint The second procedure combining complete cytoreductive surgery and intraperitoneal chemotherapy for isolated peritoneal recurrence: postoperative course and long-term outcome
    Antoine Brouquet
    Department of Surgical Oncology, Gustave Roussy Cancer Institute, Villejuif Cedex, France
    Ann Surg Oncol 16:2744-51. 2009
  3. ncbi request reprint A simple tumor load-based nomogram for surgery in patients with colorectal liver and peritoneal metastases
    Dominique Elias
    Department of Oncologic Surgery, Gustave Roussy, Villejuif, France
    Ann Surg Oncol 21:2052-8. 2014
  4. doi request reprint Neuroendocrine carcinomas: optimal surgery of peritoneal metastases (and associated intra-abdominal metastases)
    Dominique Elias
    Department of Surgery, Gustave Roussy, Cancer Campus, Villejuif, France Electronic address
    Surgery 155:5-12. 2014
  5. doi request reprint Comprehensive study of ovarian metastases in young women with peritoneal pseudomyxoma: is a preservation of fertility possible?
    D Elias
    Department of Surgery, Institut Gustave Roussy, Villejuif, France
    Eur J Surg Oncol 39:748-53. 2013
  6. doi request reprint A new policy regarding ovarian resection in young women treated for peritoneal carcinomatosis
    Dominique Elias
    Department of Surgery, Institut Gustave Roussy, Villejuif, France
    Ann Surg Oncol 20:1837-42. 2013
  7. doi request reprint Current status and future directions in the treatment of peritoneal dissemination from colorectal carcinoma
    Dominique Elias
    Department of General Oncologic Surgery, Institut Gustave Roussy, Villejuif 94805, France
    Surg Oncol Clin N Am 21:611-23. 2012
  8. doi request reprint Variation in the peritoneal cancer index scores between surgeons and according to when they are determined (before or after cytoreductive surgery)
    D Elias
    Department of Surgical Oncology, Institut Gustave Roussy, rue Camille Desmoulins, 94805 Villejuif, France
    Eur J Surg Oncol 38:503-8. 2012
  9. ncbi request reprint Impact of the extent and duration of cytoreductive surgery on postoperative hematological toxicity after intraperitoneal chemohyperthermia for peritoneal carcinomatosis
    Dominique Elias
    Department of Surgical Oncology, the Institut Gustave Roussy, Tertiary Cancer Center, France
    J Surg Oncol 90:220-5. 2005
  10. ncbi request reprint Liver abscess after radiofrequency ablation of tumors in patients with a biliary tract procedure
    Dominique Elias
    Department of Surgical Oncology, Institut Gustave Roussy, Villejuif
    Gastroenterol Clin Biol 30:823-7. 2006

Detail Information

Publications106 found, 100 shown here

  1. ncbi request reprint Liver resection (and associated extrahepatic resections) for metastatic well-differentiated endocrine tumors: a 15-year single center prospective study
    Dominique Elias
    Department of Surgical Oncology, Comprehensive Cancer Center, Institut Gustave Roussy, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Surgery 133:375-82. 2003
    ..However, surveillance alone yields only a 22% 5-year survival when metastases occur. The aim of this study was to determine the results of hepatic and extra hepatic resections and to clarify the indications of surgery...
  2. doi request reprint The second procedure combining complete cytoreductive surgery and intraperitoneal chemotherapy for isolated peritoneal recurrence: postoperative course and long-term outcome
    Antoine Brouquet
    Department of Surgical Oncology, Gustave Roussy Cancer Institute, Villejuif Cedex, France
    Ann Surg Oncol 16:2744-51. 2009
    ..However, this approach has not yet been evaluated for isolated peritoneal re-recurrences after previous IPC. The aim of this study was to evaluate the postoperative course and long-term outcome after repeat (re-)CCRS + IPC...
  3. ncbi request reprint A simple tumor load-based nomogram for surgery in patients with colorectal liver and peritoneal metastases
    Dominique Elias
    Department of Oncologic Surgery, Gustave Roussy, Villejuif, France
    Ann Surg Oncol 21:2052-8. 2014
    ....
  4. doi request reprint Neuroendocrine carcinomas: optimal surgery of peritoneal metastases (and associated intra-abdominal metastases)
    Dominique Elias
    Department of Surgery, Gustave Roussy, Cancer Campus, Villejuif, France Electronic address
    Surgery 155:5-12. 2014
    ..To report the results of complete cytoreductive surgery (CCRS) of peritoneal metastases from neuroendocrine tumor (NET) and to compare patients treated with or without hyperthermic intraperitoneal chemotherapy (HIPEC)...
  5. doi request reprint Comprehensive study of ovarian metastases in young women with peritoneal pseudomyxoma: is a preservation of fertility possible?
    D Elias
    Department of Surgery, Institut Gustave Roussy, Villejuif, France
    Eur J Surg Oncol 39:748-53. 2013
    ..To determine whether ovaries can be preserved in selected young women with peritoneal pseudomyxoma (PMP)...
  6. doi request reprint A new policy regarding ovarian resection in young women treated for peritoneal carcinomatosis
    Dominique Elias
    Department of Surgery, Institut Gustave Roussy, Villejuif, France
    Ann Surg Oncol 20:1837-42. 2013
    ..To appreciate if the ovaries can be preserved in selected young women with peritoneal carcinomatosis (PC)...
  7. doi request reprint Current status and future directions in the treatment of peritoneal dissemination from colorectal carcinoma
    Dominique Elias
    Department of General Oncologic Surgery, Institut Gustave Roussy, Villejuif 94805, France
    Surg Oncol Clin N Am 21:611-23. 2012
    ..The prognostic impact of a complete resection is high, but that of HIPEC per se is more hypothetical. The presence of a few resectable liver metastases associated with PC is not a contraindication to surgery plus HIPEC...
  8. doi request reprint Variation in the peritoneal cancer index scores between surgeons and according to when they are determined (before or after cytoreductive surgery)
    D Elias
    Department of Surgical Oncology, Institut Gustave Roussy, rue Camille Desmoulins, 94805 Villejuif, France
    Eur J Surg Oncol 38:503-8. 2012
    ..This raises the question of the concordance between the PCI scores calculated by different surgeons, and a possible variation before and after CRS...
  9. ncbi request reprint Impact of the extent and duration of cytoreductive surgery on postoperative hematological toxicity after intraperitoneal chemohyperthermia for peritoneal carcinomatosis
    Dominique Elias
    Department of Surgical Oncology, the Institut Gustave Roussy, Tertiary Cancer Center, France
    J Surg Oncol 90:220-5. 2005
    ..The aim of our study was to investigate whether surgery alone had an impact on the hematological toxicity associated with the standardized drug protocol that we routinely prescribed...
  10. ncbi request reprint Liver abscess after radiofrequency ablation of tumors in patients with a biliary tract procedure
    Dominique Elias
    Department of Surgical Oncology, Institut Gustave Roussy, Villejuif
    Gastroenterol Clin Biol 30:823-7. 2006
    ..And yet, to date this rate, the time of onset of these abscesses, and the prior status of the bile ducts have never been reported in the literature...
  11. ncbi request reprint Hepatic and extrahepatic colorectal metastases: when resectable, their localization does not matter, but their total number has a prognostic effect
    Dominique Elias
    Department of Surgical Oncology, Institut Gustave Roussy, Comprehensive Cancer Center, 39 rue Camille Desmoulins, Villejuif Cedex, 94805, France
    Ann Surg Oncol 12:900-9. 2005
    ..After resection, the prognosis is based more on the total number of resected metastases (located inside and outside the liver) than on the site of these metastases (only inside the liver or not)...
  12. ncbi request reprint [Rationale for oncological surgery in multimodal cancer treatments]
    D Elias
    Département de chirurgie digestive carcinologique, Institut Gustave Roussy Villejuif
    J Chir (Paris) 142:284-90. 2005
    ..New modalities will undoubtedly be necessary with the development of future technologies...
  13. ncbi request reprint The trans-metastasis hepatectomy (through metastases previously ablated with radiofrequency): results of a 13-case study of colorectal cancer
    Dominique Elias
    Department of Surgical Oncology, Institut Gustave Roussy, Cancer Center, Villejuif, Cedex, France
    J Surg Oncol 93:8-12. 2006
    ..Firstly, the ill-sited LM, which is located in the only feasible future hepatectomy plane, is ablated using RF; the hepatectomy is then performed through this ablated LM...
  14. ncbi request reprint Preoperative criteria of incomplete resectability of peritoneal carcinomatosis from non-appendiceal colorectal carcinoma
    Dominique Elias
    Department of Surgical Oncology, Institut Gustave Roussy, Villejuif
    Gastroenterol Clin Biol 29:1010-3. 2005
    ..To analyse the causes of non resectability of peritoneal carcinomatosis (PC) of non-appendiceal colorectal carcinomas, discovered only at the time of the laparotomy...
  15. ncbi request reprint Trans-metastasis hepatectomy: results of a 21-case study
    D Elias
    Department of Surgical Oncology, Institut Gustave Roussy, Cancer Center, Villejuif, France
    Eur J Surg Oncol 32:213-7. 2006
    ....
  16. ncbi request reprint Incidence of unsuspected and treatable metastatic disease associated with operable colorectal liver metastases discovered only at laparotomy (and not treated when performing percutaneous radiofrequency ablation)
    D Elias
    Department of Surgical Oncology, Institut Gustave Roussy, Cancer Center, 39 rue Camille Desmoulins, 94805, Villejuif Cedex, France
    Ann Surg Oncol 12:298-302. 2005
    ..This would result in a reduced cure rate. Our purpose was to discover the incidence of unsuspected and surgically treatable intrahepatic and extrahepatic metastases discovered at laparotomy...
  17. ncbi request reprint Surgical treatment of peritoneal carcinomatosis from well-differentiated digestive endocrine carcinomas
    Dominique Elias
    Division of Surgical Oncology, Department of Surgery, Gustave Roussy Institute, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Surgery 137:411-6. 2005
    ..This study was aimed at assessing the actual prognostic impact of PC and to evaluate a new treatment with respect to survival times...
  18. ncbi request reprint Hepatectomy plus intraoperative radiofrequency ablation and chemotherapy to treat technically unresectable multiple colorectal liver metastases
    Dominique Elias
    Department of Surgical Oncology, Gustave Roussy Institute, Villejuif, France
    J Surg Oncol 90:36-42. 2005
    ..Results and indications of intra-operative radiofrequency (RF) ablation of liver metastases (LM) are not well defined in the literature...
  19. ncbi request reprint [Surgical treatment of peritoneal carcinomatosis]
    D Elias
    Département de chirurgie digestive carcinologique, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Ann Chir 129:530-3. 2004
    ..This article details the technical aspect of intraperitoneal chemohyperthermia. These techniques involve specific and important features. At these conditions, peritoneal carcinomatosis can be cured in two-thirds of cases...
  20. ncbi request reprint Simultaneous percutaneous right portal vein embolization and left liver tumor radiofrequency ablation prior to a major right hepatic resection for bilateral colorectal metastases
    Dominique Elias
    Department of Surgical Oncology, Institut Gustave Roussy, Villejuif, France
    Hepatogastroenterology 51:1788-91. 2004
    ....
  21. ncbi request reprint [Surgical treatment of peritoneal carcinomatosis]
    D Elias
    Département de chirurgie digestive carcinologique, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Ann Chir 129:439-43. 2004
    ..This article details the technical aspect of peritonectomy...
  22. ncbi request reprint Treatment of peritoneal carcinomatosis from colorectal cancer: impact of complete cytoreductive surgery and difficulties in conducting randomized trials
    Dominique Elias
    Department of Surgery, Institut Gustave Roussy, Villejuif, France
    Ann Surg Oncol 11:518-21. 2004
    ..Colorectal peritoneal carcinomatosis (PC) is a frequent and very lethal event. However, cure may be possible with maximal cytoreductive surgery associated with early postoperative intraperitoneal chemotherapy (EPIC)...
  23. ncbi request reprint [Recent advances in digestive oncology (pancreas excluded)]
    Dominique Elias
    Département de chirurgie digestive carcinologique, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex
    Bull Cancer 93:61-5. 2006
    ..Two mains issues are discussed: advances in terms of the molecular basis of GI oncogenesis, and the data on molecular targeted agents for which the cost/efficacity balance needs to be addressed...
  24. ncbi request reprint Treatment of synchronous peritoneal carcinomatosis and liver metastases from colorectal cancer
    D Elias
    Department of Oncologic Digestive Surgery and Digestive Oncology, Institut Gustave Roussy, Cancer Center Hospital, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Eur J Surg Oncol 32:632-6. 2006
    ..To report our experience of peritoneal carcinomatosis (PC) discovered during abdominal exploration in patients with liver metastases (LM)...
  25. doi request reprint A comparative study of complete cytoreductive surgery plus intraperitoneal chemotherapy to treat peritoneal dissemination from colon, rectum, small bowel, and nonpseudomyxoma appendix
    Dominique Elias
    Department of Surgery, Institut Gustave Roussy, Villejuif, France
    Ann Surg 251:896-901. 2010
    ....
  26. ncbi request reprint Pseudomyxoma peritonei: a French multicentric study of 301 patients treated with cytoreductive surgery and intraperitoneal chemotherapy
    D Elias
    Department of Oncologic Surgery, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Eur J Surg Oncol 36:456-62. 2010
    ..To analyze a large series of patients with pseudomyxoma peritonei (PMP) treated with cytoreductive surgery associated with perioperative intraperitoneal chemotherapy (PIC) in 18 French-speaking centers...
  27. ncbi request reprint Hepatic metastases from neuroendocrine tumors with a "thin slice" pathological examination: they are many more than you think
    Dominique Elias
    Department of Oncologic Surgery, Institut Gustave Roussy, Cancer Center, Villejuif, France
    Ann Surg 251:307-10. 2010
    ....
  28. doi request reprint Combined liver surgery and RFA for patients with gastroenteropancreatic endocrine tumors presenting with more than 15 metastases to the liver
    D Elias
    Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, Cedex, France
    Eur J Surg Oncol 35:1092-7. 2009
    ..It is an extensive application of the current guidelines...
  29. doi request reprint Complete cytoreductive surgery plus intraperitoneal chemohyperthermia with oxaliplatin for peritoneal carcinomatosis of colorectal origin
    Dominique Elias
    Département de Chirurgie Carcinologique, Institut Gustave Roussy, Villejuif, France
    J Clin Oncol 27:681-5. 2009
    ....
  30. ncbi request reprint Peritoneal pseudomyxoma: results of a systematic policy of complete cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
    D Elias
    Department of Surgical Oncology, Gustave Roussy Institute, Villejuif, France
    Br J Surg 95:1164-71. 2008
    ..Treatment based on complete cytoreductive surgery (CCRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is gaining support. The aim of this study was to identify pre- and perioperative factors of prognostic value...
  31. ncbi request reprint "Natural history" of complete cytoreductive surgery with hyperthermic intraperitoneal chemotherapy
    D Elias
    Department of Surgical Oncology, Institut Gustave Roussy, Cancer Centre, Villejuif Cedex, France
    Eur J Surg Oncol 35:434-8. 2009
    ..This aggressive treatment is frequently followed by a complicated or an unusual postoperative course, that has yet to be described...
  32. ncbi request reprint Outcome of posthepatectomy-missing colorectal liver metastases after complete response to chemotherapy: impact of adjuvant intra-arterial hepatic oxaliplatin
    Dominique Elias
    Department of Surgical Oncology, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805, Villejuif, Cedex, France
    Ann Surg Oncol 14:3188-94. 2007
    ..In a few patients, some LMs vanish on imaging studies, remain undetected during hepatectomy, and are left in place, which defines the "missing LMs." The aim of our study was to assess the long-term outcome of such "missing LMs."..
  33. ncbi request reprint HIPEC with oxaliplatin in the treatment of peritoneal carcinomatosis of colorectal origin
    D Elias
    Institut Gustave Roussy, Department de Chirurgie, Villejuif, France
    Cancer Treat Res 134:303-18. 2007
  34. ncbi request reprint Optimization of hyperthermic intraperitoneal chemotherapy with oxaliplatin plus irinotecan at 43 degrees C after compete cytoreductive surgery: mortality and morbidity in 106 consecutive patients
    Dominique Elias
    Department of Surgical Oncology, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, Cedex, France
    Ann Surg Oncol 14:1818-24. 2007
    ....
  35. ncbi request reprint Comparison of two kinds of intraperitoneal chemotherapy following complete cytoreductive surgery of colorectal peritoneal carcinomatosis
    Dominique Elias
    Departement de Chirurgie Oncologique, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805, Villejuif, Cedex, France
    Ann Surg Oncol 14:509-14. 2007
    ..To date, the results of these procedures have never been compared...
  36. ncbi request reprint Peritoneal carcinomatosis of colorectal origin
    Dominique Elias
    Department of Surgical Oncology, Institut Gustave Roussy, Villejuif
    Gastroenterol Clin Biol 30:1200-4. 2006
    ..We report long-term results concerning survival of a phase II study using oxaliplatin (LOHP)...
  37. ncbi request reprint [Rational of oncological surgery in multimodality treatment of cancers]
    Dominique Elias
    Département de chirurgie digestive carcinologique, Institut Gustave Roussy, rue Camille Desmoulins, 94805 Ville juif Cedex
    Bull Cancer 93:775-81. 2006
    ..At last, considering the future technologies, we must elaborate the future modalities of the oncological surgery...
  38. ncbi request reprint Heated intra-operative intraperitoneal oxaliplatin alone and in combination with intraperitoneal irinotecan: Pharmacologic studies
    D Elias
    Department of Oncological Surgery, Institut Gustave Roussy Comprehensive Cancer Center, 39 rue Camille Desmoulins, 94805 Villejuif, France
    Eur J Surg Oncol 32:607-13. 2006
    ..A third pharmacokinetic study was to determine the appropriate dose of intraperitoneal oxaliplatin combined with intraperitoneal irinotecan: the recommended dosage was 360 mg/m2 for each of the chemotherapy agents...
  39. ncbi request reprint Efficacy of intraperitoneal chemohyperthermia with oxaliplatin in colorectal peritoneal carcinomatosis. Preliminary results in 24 patients
    D Elias
    Department of Surgical Oncology, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Ann Oncol 15:781-5. 2004
    ..We report preliminary results on survival in a phase II study using oxaliplatin (LOHP)...
  40. ncbi request reprint Local recurrences after intraoperative radiofrequency ablation of liver metastases: a comparative study with anatomic and wedge resections
    Dominique Elias
    Division of Surgical Oncology, Department of Surgery, Gustave Roussy Institute, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Ann Surg Oncol 11:500-5. 2004
    ..The aim of the study was to appreciate the local recurrence rate of RFA in comparison with anatomic and wedge resection...
  41. ncbi request reprint [Radiofrequency for the treatment of liver tumors]
    D Elias
    Service de Chirurgie Digestive Carcinologique, Institut Gustave Roussy Villejuif, Cedex, France
    J Chir (Paris) 138:81-8. 2001
    ..radiofrequency, like other tools for local tumor destruction, will greatly change our therapeutic strategies in the neat future...
  42. ncbi request reprint [Pseudomyxoma peritonei treated with complete resection and immediate intraperitoneal chemotherapy]
    Dominique Elias
    Département de Chirurgie Générale Carcinologique, Institut Gustave Roussy, rue Camille Desmoulins, 94805, Villejuif Cedex
    Gastroenterol Clin Biol 27:407-12. 2003
    ..The aim of this prospective study was to evaluate this treatment strategy...
  43. ncbi request reprint Incidence, distribution, and significance of hilar lymph node metastases in hepatic colorectal metastases
    Dominique M Elias
    Department of Surgical Oncology, Institut Gustave Roussy, Comprehensive Cancer Center, 39 rue Camille Desmoulins, 94805 Villejuif, France
    Surg Oncol Clin N Am 12:221-9. 2003
    ..Systematic routine en bloc lymphadenectomy currently has no prognostic value and no known therapeutic effects...
  44. ncbi request reprint Extrahepatic disease does not contraindicate hepatectomy for colorectal liver metastases
    D Elias
    Department of Surgical Oncology, Institut Gustave Roussy, Villejuif, France
    Br J Surg 90:567-74. 2003
    ..The present study reports the long-term outcome and prognostic factors of patients undergoing resection of extrahepatic disease simultaneously with hepatectomy for liver metastases...
  45. ncbi request reprint Research on the best chemohyperthermia technique of treatment of peritoneal carcinomatosis after complete resection
    D Elias
    Department of Oncological Surgery, Institut Gustave Roussy, Comprehensive Cancer Center, France
    Int J Surg Investig 1:431-9. 2000
    ..The complete or almost complete resection of peritoneal carcinomatosis (PC) followed by intraperitoneal chemohyperthermia (IPCH) is potentially capable of curing some patients presenting with disease confined to the peritoneum...
  46. ncbi request reprint Usefulness of intraoperative radiofrequency thermoablation of liver tumours associated or not with hepatectomy
    D Elias
    Departments of Surgical Oncology, Interventional Radiology, and Pathology, Institut Gustave Roussy, Comprehensive Cancer Center, Villejuif Cedex, 94805, France
    Eur J Surg Oncol 26:763-9. 2000
    ....
  47. ncbi request reprint Human pharmacokinetic study of heated intraperitoneal oxaliplatin in increasingly hypotonic solutions after complete resection of peritoneal carcinomatosis
    D Elias
    Department of Surgical Oncology, Institut Gustave Roussy, Villejuif, France
    Oncology 63:346-52. 2002
    ..p.) oxaliplatin (LOHP) solution and its safety profile in increasingly hypotonic solutions. This is the first clinical study of i.p. chemohyperthermia with hypotonic solutions...
  48. ncbi request reprint [Perioperative autotransfusion with salvage blood in cancer surgery]
    D Elias
    Service de chirurgie carcinologique générale, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif, France
    Ann Fr Anesth Reanim 19:739-44. 2000
    ..The goal of this review was to discuss the risk associated with this technique, and the way to minimize it...
  49. ncbi request reprint Percutaneous radiofrequency thermoablation as an alternative to surgery for treatment of liver tumour recurrence after hepatectomy
    D Elias
    Department of Surgical Oncolog, Comprehensive Cancer Centre, Institut Gustave Roussy, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Br J Surg 89:752-6. 2002
    ..This study assessed whether percutaneous RF ablation is a useful and safe technique for the treatment of liver tumour recurrence after hepatectomy...
  50. ncbi request reprint [Treatment of desmoid tumors of the mesenteric root]
    D Elias
    Service de Chirurgie Digestive Carcinologique, Institut Gustave Roussy, Villejuif
    Presse Med 29:408-12. 2000
    ..To elaborate a therapeutic scheme for desmoid tumors developing within the mesenteric root. These uncommon and often unrecognized tumors are difficult to treat as they lie very close to the superior mesenteric vessels...
  51. ncbi request reprint Results of lymphadenectomy for obvious lateroaortic lymph node metastases from colorectal primaries
    D Elias
    Department of Digestive Oncological Surgery, Medical Oncology, and Radiotherapy, Institut Gustave Roussy, Comprehensive Cancer Center, Villejuif, France
    Hepatogastroenterology 48:123-7. 2001
    ..To analyze the results of surgery for macroscopically or radiologically obvious (i.e., easily detectable by computed tomography scan or by palpation) synchronous or metachronous lateroaortic lymph node metastases from colorectal primaries...
  52. doi request reprint Peritoneal colorectal carcinomatosis treated with surgery and perioperative intraperitoneal chemotherapy: retrospective analysis of 523 patients from a multicentric French study
    Dominique Elias
    Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805, Villejuif, Cedex, France
    J Clin Oncol 28:63-8. 2010
    ..These results should improve in the future, because the different teams involved will gain experience. This approach, when feasible, is now considered the gold standard in the French guidelines...
  53. ncbi request reprint Heated intra-operative intraperitoneal oxaliplatin after complete resection of peritoneal carcinomatosis: pharmacokinetics and tissue distribution
    D Elias
    Department of Surgical Oncology, Institut Gustave Roussy Comprehensive Cancer Center, Villejuif, France
    Ann Oncol 13:267-72. 2002
    ..Oxaliplatin has demonstrated significant activity in advanced colorectal cancer, and this is the first publication concerning its intraperitoneal administration...
  54. ncbi request reprint Curative treatment of peritoneal carcinomatosis arising from colorectal cancer by complete resection and intraperitoneal chemotherapy
    D Elias
    Department of Oncological Surgery, Gustave Roussy Institute, Villejuif, France
    Cancer 92:71-6. 2001
    ..A new approach that combines maximal surgery with maximal regional chemotherapy has potential to cure selected patients who have colorectal PC. The authors have reported the oncologic results of this combined treatment...
  55. ncbi request reprint Reflections and proposals for the standardization of lymphadenectomy for gastric carcinoma
    D Elias
    Department of Surgical Oncology, Institut Gustave Roussy, Comprehensive Cancer Center, Villejuif, France
    Eur J Surg Oncol 26:6-10. 2000
    ..These simple, reproducible guidelines offer a basis for the standardization of procedures used for the treatment and classification of gastric carcinomas...
  56. ncbi request reprint [Pseudomyxoma peritonei. A review]
    D Elias
    Département de Chirurgie Générale Carcinologique, Institut Gustave Roussy, Villejuif
    J Chir (Paris) 136:341-7. 1999
    ..The adjunction of an intraperitoneal chemo-hyperthermia is logical for these two types of disease and probably increases the survival rate...
  57. ncbi request reprint [Resectional treatment of peritoneal carcinomatosis followed by intraperitoneal chemotherapy, practical aspects]
    D Elias
    Département de chirurgie digestive carcinologique, Institut Gustave Roussy, Villejuif
    J Chir (Paris) 140:270-6. 2003
    ..If these conditions can be met, peritoneal metastases can be definitively cured in two thirds of colorectal PC and pseudomyxoma peritonei, and in nearly half of mesotheliomas...
  58. ncbi request reprint Necrotizing pancreatitis after radiofrequency destruction of pancreatic tumours
    D Elias
    Department of Surgical Oncology, Gustave Roussy Institute, 39 rue Camille Desmoulins, 94805 Villejuif, Cedex, France
    Eur J Surg Oncol 30:85-7. 2004
    ..Intraoperative radiofrequency (RF) can be used to treat multiple small pancreatic tumours...
  59. ncbi request reprint Treatment of liver metastases with moderate peritoneal carcinomatosis by hepatectomy and cytoreductive surgery followed by immediate post-operative intraperitoneal chemotherapy: feasibility and preliminary results
    D Elias
    Department of Oncologic Digestive Surgery, Institut Gustave Roussy, Cancer Center Hospital, Villejuif, France
    Hepatogastroenterology 46:360-3. 1999
    ..The purpose of this study is to report tolerance and preliminary results in patients with liver metastases synchronous to moderate PC, treated with hepatectomy, complete cytoreductive surgery, and IPIC...
  60. ncbi request reprint Results of 136 curative hepatectomies with a safety margin of less than 10 mm for colorectal metastases
    D Elias
    Department of Oncologic Surgery, Institut Gustave Roussy, Comprehensive Cancer Centre, Villejuif, France
    J Surg Oncol 69:88-93. 1998
    ..The true impact of the width of the margin on the prognosis is unclear...
  61. ncbi request reprint Results of R0 resection for colorectal liver metastases associated with extrahepatic disease
    Dominique Elias
    Department of Surgical Oncology, Gustave Roussy Institute, Villejuif, France
    Ann Surg Oncol 11:274-80. 2004
    ..This study reports the long-term outcome and prognostic factors of patients undergoing extrahepatic disease resection simultaneously with hepatectomy for liver metastases...
  62. ncbi request reprint Evolution of missing colorectal liver metastases following inductive chemotherapy and hepatectomy
    Dominique Elias
    Department of Surgical Oncology, Gustave Roussy Institute, Villejuif, France
    J Surg Oncol 86:4-9. 2004
    ..Our study was aimed at assessing the evolution of these metastases when they were also not found during liver surgery...
  63. ncbi request reprint Preliminary results of intraperitoneal chemohyperthermia with oxaliplatin in peritoneal carcinomatosis of colorectal origin
    D Elias
    Department of Surgical Oncology, Institut Gustave Roussy, Villejuif, France
    Br J Surg 91:455-6. 2004
  64. ncbi request reprint Regional chemotherapeutic techniques for liver tumors: current knowledge and future directions
    Dominique Elias
    Division of Surgical Oncology, Department of Surgery, Gustave Roussy Institute, rue Camille Desmoulins, 94805, Villejuif, France
    Surg Clin North Am 84:607-25. 2004
    ..At the same time, resectability rates are increasing with the assistance of local ablative physical treatments such as radiofrequency, resulting in an improvement of patients' median survival rates and quality of life...
  65. ncbi request reprint Pharmacokinetics of heated intraoperative intraperitoneal oxaliplatin after complete resection of peritoneal carcinomatosis
    Dominique M Elias
    Department of Surgery, Institut Gustave Roussy, Comprehensive Cancer Center, 39 rue Camille Desmoulins, Villejuif, 94805, France
    Surg Oncol Clin N Am 12:755-69, xiv. 2003
    ..A pharmacokinetic study using intraperitoneal oxaliplatin at the same dose but in various hypotonic solutions did not show any specific pharmacologic advantage and was associated with excessive postoperative bleeding...
  66. ncbi request reprint [Long-term oncological results of hepatectomy performed after selective portal embolization]
    D Elias
    Service de Chirurgie Digestive Carcinologique, Institut Gustave Roussy, Villejuif
    Ann Chir 53:559-64. 1999
    ..The objective of this retrospective study was to assess the long-term survival of this unusual therapeutic approach...
  67. ncbi request reprint Treatment and prevention of peritoneal carcinomatosis from colorectal cancer
    Dominique M Elias
    Departement de Chirurgie, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805, Villejuif, France
    Surg Oncol Clin N Am 12:543-59. 2003
    ..Prospective studies must be conducted in the prevention of carcinomatosis in well-defined high-risk patients...
  68. ncbi request reprint Inguinal canal as an anatomic sanctuary site of relapse in peritoneal carcinomatosis previously treated with intraperitoneal chemotherapy
    Gabriel Liberale
    Department of Surgical Oncology, Gustave Roussy Institute, Villejuif, France
    J Surg Oncol 91:73-6. 2005
    ..A local recurrence is thus possible. New clinical presentations such as this one have first to be described in order to improve patient follow-up...
  69. ncbi request reprint Hepatic arterial infusion of oxaliplatin and intravenous LV5FU2 in unresectable liver metastases from colorectal cancer after systemic chemotherapy failure
    Valerie Boige
    Department of Medicine, Institut Gustave Roussy, Villejuif, France
    Ann Surg Oncol 15:219-26. 2008
    ..Whether this regimen could be beneficial after systemic chemotherapy failure is unknown...
  70. ncbi request reprint [Positron emission tomography and gastrointestinal oncology]
    Michel Ducreux
    Institut Gustave Roussy, rue Camille Desmoulins, 94805 Villejuif Cedex
    Gastroenterol Clin Biol 27:B71-8. 2003
  71. ncbi request reprint Cytoreductive surgery plus intraperitoneal chemohyperthermia in patients with colorectal cancer at high risk for local-regional recurrence
    Jeremie H Lefevre
    Department of Oncologic Surgery, Institut Gustave Roussy, Villejuif, France
    Cancer J 15:200-3. 2009
    ..The benefit seems considerably lower for the other groups of high-risk patients...
  72. ncbi request reprint Preoperative selective portal vein embolization before hepatectomy for liver metastases: long-term results and impact on survival
    Dominique Elias
    Department of Surgical Oncology and the Interventional Radiology Unit, Institut Gustave Roussy, Villejuif, Cedex, France
    Surgery 131:294-9. 2002
    ..Preoperative portal vein embolization (PVE) is an effective means of creating hypertrophy of the FRL, thus permitting safe hepatic resection. The aim of this retrospective study was to investigate the long-term results of this technique...
  73. ncbi request reprint Combination chemotherapy in advanced small bowel adenocarcinoma
    Christophe Locher
    Gastroenterology Unit, Institut Gustave Roussy, Villejuif, France
    Oncology 69:290-4. 2005
    ..To assess the efficacy of 5-fluorouracil (5-FU) and either platinum compounds or irinotecan in patients with advanced small bowel adenocarcinoma (SBA), for whom data on the efficacy of chemotherapy are scarce...
  74. ncbi request reprint An attempt to clarify indications for hepatectomy for liver metastases from breast cancer
    Dominique Elias
    Department of Surgical Oncology, Institut Gustave Roussy, Cancer Center, Villejuif, France
    Am J Surg 185:158-64. 2003
    ..Liver metastases (LM) from breast cancer are generally considered as disseminated disease with a poor prognosis. However in selected patients hepatectomy may be an important adjunct to systemic treatment...
  75. ncbi request reprint Malignant peritoneal mesothelioma: treatment with maximal cytoreductive surgery plus intraperitoneal chemotherapy
    Dominique Elias
    Département de chirurgie générale oncologique, Institut Gustave Roussy, 39 rue Camille Desmoulins, Villejuif Cedex
    Gastroenterol Clin Biol 31:784-8. 2007
    ....
  76. ncbi request reprint Catalytic subunit of human telomerase reverse transcriptase is an independent predictor of survival in patients undergoing curative resection of hepatic colorectal metastases: a multicenter analysis
    Julien Domont
    Institut Gustave Roussy, Division of Cancer Médecine, 39 rue Camille Desmoulins, 94805 Villejuif, France
    J Clin Oncol 23:3086-93. 2005
    ..To determine the role of the catalytic subunit of human telomerase reverse transcriptase (hTERT) in predicting survival after resection of hepatic colorectal metastases (CRM)...
  77. doi request reprint The long-term impact of hyperthermic intraperitoneal chemotherapy on survivors treated for peritoneal carcinomatosis: a cross-sectional study
    Franck Zenasni
    Department of Psycho oncology, Institut Gustave Roussy, Villejuif, Paris, France
    Support Care Cancer 17:1255-61. 2009
    ..Hyperthermic intraperitoneal chemotherapy (HIPEC) after complete surgical resection is currently accepted as a therapeutic option for peritoneal carcinomatosis. However, considerable morbidity is reported after HIPEC...
  78. ncbi request reprint Cost of radiofrequency ablation in the treatment of hepatic malignancies
    Julia Bonastre
    Department of Health Economics, Gustave Roussy Institute, 39 rue Camille Desmoulins, Villejuif Cedex
    Gastroenterol Clin Biol 31:828-35. 2007
    ..Our primary objective was to assess the cost of radio-frequency ablation (RFA) of hepatic malignancies and to compare it to hospital reimbursement paid in the French Prospective Payment System (PPS)...
  79. doi request reprint Predictive factors for hypertrophy of the future remnant liver after selective portal vein embolization
    Thierry de Baere
    Department of Interventional Radiology, Institut Gustave Roussy, Villejuif, France
    Ann Surg Oncol 17:2081-9. 2010
    ..To analyze predictive factors of hypertrophy of the nonembolized future remnant liver (FRL) after transhepatic preoperative portal vein embolization (PVE) of the liver to be resected...
  80. doi request reprint Prolonged survival of initially unresectable hepatic colorectal cancer patients treated with hepatic arterial infusion of oxaliplatin followed by radical surgery of metastases
    Diane Goere
    Department of Surgical Oncology, Institut Gustave Roussy, Villejuif Cedex, France
    Ann Surg 251:686-91. 2010
    ..The aim of this study was to analyze the impact of hepatic arterial infusion (HAI) of oxaliplatin with systemic 5-Fluorouracil and leucovorin on patients with isolated unresectable liver metastases...
  81. doi request reprint Performance of (18)fluorodeoxyglucose-positron emission tomography and somatostatin receptor scintigraphy for high Ki67 (≥10%) well-differentiated endocrine carcinoma staging
    Ronan Abgral
    Department of Nuclear Medicine, University Hospital of Brest, 29200 Brest, France
    J Clin Endocrinol Metab 96:665-71. 2011
    ....
  82. doi request reprint Percutaneous femoral implantation of an arterial port catheter for intraarterial chemotherapy: feasibility and predictive factors of long-term functionality
    Frederic Deschamps
    Interventional Radiology Department, Gustave Roussy Institut, Villejuif, France
    J Vasc Interv Radiol 21:1681-8. 2010
    ..To evaluate the feasibility, functionality, and dysfunctions of an arterial port catheter implanted via the femoral artery...
  83. doi request reprint Prognostic factors influencing survival from metastatic (stage IV) gastroenteropancreatic well-differentiated endocrine carcinoma
    Cosimo Durante
    Service de Médecine Nucléaire et de Cancérologie Endocrinienne, Institut Gustave Roussy, Universite Paris XI, 94805 Villejuif Cedex, France
    Endocr Relat Cancer 16:585-97. 2009
    ..This study enables the stratification of metastatic GEP WDEC patients into distinct risk groups. These risk categories can be used to tailor therapeutic approaches and also to design and interpret clinical trials...
  84. doi request reprint Oncologic and functional results after abdominoperineal resection plus pseudocontinent perineal colostomy for epidermoid carcinoma of the anus
    Diane Goere
    Department of Surgical Oncology, Institut Gustave Roussy, Cancer Center, Villejuif, France
    Dis Colon Rectum 52:958-63. 2009
    ....
  85. ncbi request reprint Hepatic malignancies: percutaneous radiofrequency ablation during percutaneous portal or hepatic vein occlusion
    Thierry de Baere
    Department of Interventional Radiology, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Cedex, Villejuif, France
    Radiology 248:1056-66. 2008
    ....
  86. ncbi request reprint Adverse events during radiofrequency treatment of 582 hepatic tumors
    Thierry de Baere
    Departement d Imagerie Medicale et de Chirurgie, Institut Gustave Roussy, 39 rue Camille Desmoulins, Villejuif 94805, France
    AJR Am J Roentgenol 181:695-700. 2003
    ..The chi-square test was used for a group-to-group comparison of the occurrence of adverse events...
  87. ncbi request reprint Computed tomographic features of peritoneal carcinomatosis treated by intraperitoneal chemohyperthermia
    Clarisse Dromain
    Department of Radiology, Institut Gustave Roussy, Vellejuif, France
    J Comput Assist Tomogr 27:327-32. 2003
    ..The purpose of this work was to describe the computed tomography (CT) features of peritoneal carcinomatosis after surgery combined with intraperitoneal chemohyperthermia (IPCH)...
  88. ncbi request reprint Hepatic arterial oxaliplatin infusion plus intravenous chemotherapy in colorectal cancer with inoperable hepatic metastases: a trial of the gastrointestinal group of the Federation Nationale des Centres de Lutte Contre le Cancer
    Michel Ducreux
    Gastrointestinal Unit, Institut Gustave Roussy, 94805 Villejuif Cedex, France
    J Clin Oncol 23:4881-7. 2005
    ....
  89. ncbi request reprint Trans-catheter arterial chemoembolization as first-line treatment for hepatic metastases from endocrine tumors
    Alain Roche
    Service de Radiologie Interventionnelle, Institut Gustave Roussy, rue Camille Desmoulins 39, 94805 Villejuif Cedex, France
    Eur Radiol 13:136-40. 2003
    ..Long-term palliation is possible in unresectable liver metastases from digestive neuroendocrine tumors with a few sessions of TACE as first-line and eventually exclusive treatment...
  90. ncbi request reprint Usefulness of guiding needles for radiofrequency ablative treatment of liver tumors
    Thierry de Baere
    Département d Imagerie Médicale, Institut Gustave Roussy, Villejuif 94805, France
    Cardiovasc Intervent Radiol 29:650-4. 2006
    ..To evaluate the usefulness of a guiding needle for radiofrequency (RF) ablative treatment of liver tumors...
  91. ncbi request reprint Detection of liver metastases from endocrine tumors: a prospective comparison of somatostatin receptor scintigraphy, computed tomography, and magnetic resonance imaging
    Clarisse Dromain
    Department of Radiology, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    J Clin Oncol 23:70-8. 2005
    ..To define predictive factors for "high-sensitivity SRS."..
  92. ncbi request reprint [Colon and rectal tumours]
    Michel Ducreux
    Service d Oncologie Digestive, Institut Gustave Roussy, 94805 Villejuif
    Rev Prat 55:1241-7. 2005
  93. ncbi request reprint Ex vivo sentinel lymph node study for rectal adenocarcinoma: preliminary study
    Olivier Baton
    Department of Surgical Oncology, Institut Gustave Roussy, Comprehensive Cancer Center, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
    World J Surg 29:1166-70, discussion 1171. 2005
    ..Classic analysis using H&E remains the gold standard. However, SLNs detection can change the tumor stage by upstaging nearly 15% of the tumors from T2-3N0 to T2-3 N+...
  94. ncbi request reprint Transmetastasis curative liver resection immediately following radiofrequency destruction
    Jean Francois Ouellet
    Department of Surgical Oncology, Institut Gustave Roussy, Villejuif, France
    J Surg Oncol 81:108-10. 2002
  95. ncbi request reprint Peritoneal carcinomatosis of colorectal origin: recent advances and future evolution toward a curative treatment
    Dominique Elias
    Department of Surgical Oncology, Gustave Roussy Institute, Villejuif, France
    Recent Results Cancer Res 169:115-22. 2007
  96. ncbi request reprint Staging of peritoneal carcinomatosis: enhanced CT vs. PET/CT
    Clarisse Dromain
    Department of Radiology, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805, Villejuif Cedex, France
    Abdom Imaging 33:87-93. 2008
    ..To assess and compare the performance of CT and 18F-FDG-PET/CT in the evaluation of peritoneal carcinomatosis (PC)...
  97. ncbi request reprint Hepatic tumors treated with percutaneous radio-frequency ablation: CT and MR imaging follow-up
    Clarisse Dromain
    Department of Radiology, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France
    Radiology 223:255-62. 2002
    ....
  98. ncbi request reprint The multidisciplinary management of gastrointestinal cancer. Pancreatic cancer: from pathogenesis to cure
    Michel Ducreux
    Unité de Gastroentérologie, Departement de Medecine, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Best Pract Res Clin Gastroenterol 21:997-1014. 2007
    ..For advanced disease, chemotherapy alone has given very disappointing results. A multidisciplinary approach combining biological assessment of targets with clinical trials to evaluate new targeted drugs should be considered...
  99. ncbi request reprint Benefits of contrast-enhanced sonography for the detection of liver lesions: comparison with histologic findings
    Linda Chami
    Department of Medical Imaging, Institut Gustave Roussy, 39 rue Camille Desmoulins, Villejuif 94805, France corrected
    AJR Am J Roentgenol 190:683-90. 2008
    ..The objective of our study was to compare the usefulness of contrast-enhanced sonography with baseline sonography in detecting malignant liver lesions...
  100. doi request reprint Cost-effectiveness of intraperitoneal chemohyperthermia in the treatment of peritoneal carcinomatosis from colorectal cancer
    Julia Bonastre
    Health Economics Department, Gustave Roussy Institute, Villejuif, France
    Value Health 11:347-53. 2008
    ..Our purpose was to assess the cost-effectiveness of intraperitoneal chemohyperthermia (IPCH) compared to palliative chemotherapy (STANDARD) against peritoneal carcinomatosis arising from colorectal cancer...
  101. ncbi request reprint [The sentinel lymph node in carcinomas of the digestive tract]
    Dominique Elias
    Départements de chirurgie carcinologique et d anatomo pathologie, Institut Gustave Roussy, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Bull Cancer 89:593-8. 2002
    ..If the SLN is proven disease free, only very limited and microinvasive resections would be required to treat some digestive cancers with a curative intent...