Anne Dupressoir


Affiliation: Institut Gustave Roussy
Country: France


  1. Dupressoir A, Heidmann T. [Syncytins - retroviral envelope genes captured for the benefit of placental development]. Med Sci (Paris). 2011;27:163-9 pubmed publisher
    ..This constitutes a remarkable example of convergent evolution where the properties of retroviral envelope genes are subverted to play a major physiological role. ..
  2. Dupressoir A, Morel A, Barbot W, Loireau M, Corbo L, Heidmann T. Identification of four families of yCCR4- and Mg2+-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding. BMC Genomics. 2001;2:9 pubmed
  3. Dupressoir A, Vernochet C, Harper F, Guégan J, Dessen P, Pierron G, et al. A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast. Proc Natl Acad Sci U S A. 2011;108:E1164-73 pubmed publisher
    ..Although some are absolutely required for completion of pregnancy, others are still amenable to "epigenetic" compensations, thus illustrating the complexity of the molecular machinery that developed during placental evolution. ..
  4. Vernochet C, Redelsperger F, Harper F, Souquere S, Catzeflis F, Pierron G, et al. The captured retroviral envelope syncytin-A and syncytin-B genes are conserved in the Spalacidae together with hemotrichorial placentation. Biol Reprod. 2014;91:148 pubmed publisher
    ..These findings argue for a role of syncytin gene capture in the establishment of the original hemotrichorial placenta of Muroidea, and more generally in the diversity of placental structures among mammals. ..