P Despres

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. pmc Pediatric measles vaccine expressing a dengue antigen induces durable serotype-specific neutralizing antibodies to dengue virus
    Samantha Brandler
    Viral Genomics and Vaccination Laboratory, Institut Pasteur, CNRS URA3015, Paris, France
    PLoS Negl Trop Dis 1:e96. 2007
  2. pmc Dermal-type macrophages expressing CD209/DC-SIGN show inherent resistance to dengue virus growth
    Wing Hong Kwan
    CNRS, Laboratory of Therapeutic Immunology and Chemistry, IBMC, Universite Louis Pasteur, Strasbourg, France
    PLoS Negl Trop Dis 2:e311. 2008
  3. pmc The Israeli strain IS-98-ST1 of West Nile virus as viral model for West Nile encephalitis in the Old World
    Marianne Lucas
    Unité des Interactions Moléculaires Flavivirus Hôtes, Institut Pasteur, Paris, France
    Virol J 1:9. 2004
  4. ncbi request reprint Live measles vaccine expressing the secreted form of the West Nile virus envelope glycoprotein protects against West Nile virus encephalitis
    Philippe Despres
    Unité des Interactions Moléculaires Flavivirus Hôtes, Institut Pasteur, 25 rue du Dr Roux, 75015 Paris, France
    J Infect Dis 191:207-14. 2005
  5. pmc Apoptosis in the mouse central nervous system in response to infection with mouse-neurovirulent dengue viruses
    P Despres
    Unité des Arbovirus et Virus des Fièvres Hémorragiques, Institut Pasteur, Paris, France
    J Virol 72:823-9. 1998
  6. pmc Human isolates of dengue type 1 virus induce apoptosis in mouse neuroblastoma cells
    P Despres
    Unité des Arbovirus et Virus des Fièvres Hémorragiques, Institut Pasteur, Paris, France
    J Virol 70:4090-6. 1996
  7. doi request reprint Pediatric measles vaccine expressing a dengue tetravalent antigen elicits neutralizing antibodies against all four dengue viruses
    Samantha Brandler
    Viral Genomics and Vaccination Unit, Institut Pasteur, CNRS URA3015, 28 rue du Dr Roux, 75015 Paris, France
    Vaccine 28:6730-9. 2010
  8. ncbi request reprint Differences between cell membrane fusion activities of two dengue type-1 isolates reflect modifications of viral structure
    P Despres
    Unité des Arbovirus et Virus des Fièvres Hémorragiques, Institut Pasteur, Paris, France
    Virology 196:209-19. 1993
  9. ncbi request reprint Variations in biological features of West Nile viruses
    V Deubel
    Institut Pasteur, Unité de Biologie des Infections Virales Emergentes, Lyon, France
    Ann N Y Acad Sci 951:195-206. 2001
  10. ncbi request reprint Production and characterization of mouse monoclonal antibodies reactive to Chikungunya envelope E2 glycoprotein
    Anne Claire Brehin
    Interactions Moléculaires Flavivirus Hôtes, Institut Pasteur, 75724 Paris, France
    Virology 371:185-95. 2008

Collaborators

  • Pierre Emmanuel Ceccaldi
  • Marianne Lucas
  • Antoine Gessain
  • Frederic Tangy
  • N Berthet
  • Jean Marc Reynes
  • Michèle Février
  • Eva Harris
  • Olivier Schwartz
  • Isabelle Schuffenecker
  • M Flamand
  • Hugues Bedouelle
  • L Frangeul
  • Felix A Rey
  • M Lafon
  • Jean Louis Virelizier
  • G Dadaglio
  • Samantha Brandler
  • Vincent Deubel
  • Marie Pascale Frenkiel
  • Anne Claire Brehin
  • Simona Ozden
  • Thérèse Couderc
  • Anna Kajaste-Rudnitski
  • Marion Sourisseau
  • Fernando Arenzana-Seisdedos
  • C Filippone
  • Erika Navarro-Sanchez
  • Tomoji Mashimo
  • Eva Mertens
  • Wing Hong Kwan
  • Vincent Mouly
  • Matthew L Albert
  • Alain Michault
  • Clementine Schilte
  • Florence Guivel-Benhassine
  • Philippe V Afonso
  • Clarisse Lorin
  • Jean Louis Guenet
  • A Catteau
  • Adeline Catteau
  • S Murri
  • N Mollard
  • N Tordo
  • S Chinikar
  • V Caro
  • P Marianneau
  • T Avsic-Zupanc
  • Shessy Torres
  • Anneke Funk
  • Alexander A Khromykh
  • Isabelle Iteman
  • Isabelle Casademont
  • Anavaj Sakuntabhai
  • Cecile Julier
  • Olivier Disson
  • Menogh Valentine
  • Marion Decossas
  • Priscilla Lapalud
  • Martha Erika Navarro-Sanchez
  • Michel Chretien
  • Nabil G Seidah
  • Valerie Marechal
  • Yves Jacob
  • Laetitia Rubrecht
  • Gillian Butler-Browne
  • Flavia Barreto dos Santos
  • Daniel Laune
  • Pierre Olivier Vidalain
  • Marianne Lucas-Hourani
  • Suzanne Benjannet
  • Hélène Dumortier
  • Nadège Cayet
  • Madly Brigitte
  • Ajoy Basak
  • Juliette Mouriès
  • Kamel Mamchaoui
  • Hortense Vachon
  • Josée Hamelin
  • Amadou Alpha Sall
  • Yasmina Touret
  • Hervé W Fridman
  • Fabrice Chretien
  • Marc Lecuit
  • Christopher G Mueller
  • Georges Barau
  • Marie Christine Prevost
  • Dominika Rudnicka
  • Karin Le Roux
  • Hafida Fsihi

Detail Information

Publications27

  1. pmc Pediatric measles vaccine expressing a dengue antigen induces durable serotype-specific neutralizing antibodies to dengue virus
    Samantha Brandler
    Viral Genomics and Vaccination Laboratory, Institut Pasteur, CNRS URA3015, Paris, France
    PLoS Negl Trop Dis 1:e96. 2007
    ..The protective efficacy of this vaccine should be studied in non-human primates. A combined measles-dengue vaccine might provide a one-shot approach to immunize children against both diseases where they co-exist...
  2. pmc Dermal-type macrophages expressing CD209/DC-SIGN show inherent resistance to dengue virus growth
    Wing Hong Kwan
    CNRS, Laboratory of Therapeutic Immunology and Chemistry, IBMC, Universite Louis Pasteur, Strasbourg, France
    PLoS Negl Trop Dis 2:e311. 2008
    ..Dermal macrophages express CD209, yet little is known about their role in dengue virus infection...
  3. pmc The Israeli strain IS-98-ST1 of West Nile virus as viral model for West Nile encephalitis in the Old World
    Marianne Lucas
    Unité des Interactions Moléculaires Flavivirus Hôtes, Institut Pasteur, Paris, France
    Virol J 1:9. 2004
    ..These results demonstrate that Israeli strain IS-98-ST1 provides a suitable viral model for WNV-induced disease associated with recent WNV outbreaks in the Old World...
  4. ncbi request reprint Live measles vaccine expressing the secreted form of the West Nile virus envelope glycoprotein protects against West Nile virus encephalitis
    Philippe Despres
    Unité des Interactions Moléculaires Flavivirus Hôtes, Institut Pasteur, 25 rue du Dr Roux, 75015 Paris, France
    J Infect Dis 191:207-14. 2005
    ..The present study is the first to report that a recombinant live attenuated vector based on an approved and widely used MV vaccine can protect against a heterologous, medically important pathogen...
  5. pmc Apoptosis in the mouse central nervous system in response to infection with mouse-neurovirulent dengue viruses
    P Despres
    Unité des Arbovirus et Virus des Fièvres Hémorragiques, Institut Pasteur, Paris, France
    J Virol 72:823-9. 1998
    ..However, DEN virus-induced apoptosis in these cells was more pronounced after infection with the neurovirulent variants than after infection with the parental strain...
  6. pmc Human isolates of dengue type 1 virus induce apoptosis in mouse neuroblastoma cells
    P Despres
    Unité des Arbovirus et Virus des Fièvres Hémorragiques, Institut Pasteur, Paris, France
    J Virol 70:4090-6. 1996
    ..Accumulation of viral proteins in the endoplasmic reticulum may induce stress and thereby activate the apoptotic pathway in mouse neuroblastoma cells...
  7. doi request reprint Pediatric measles vaccine expressing a dengue tetravalent antigen elicits neutralizing antibodies against all four dengue viruses
    Samantha Brandler
    Viral Genomics and Vaccination Unit, Institut Pasteur, CNRS URA3015, 28 rue du Dr Roux, 75015 Paris, France
    Vaccine 28:6730-9. 2010
    ..A combined measles-dengue vaccine might be attractive to immunize infants against both diseases where they co-exist...
  8. ncbi request reprint Differences between cell membrane fusion activities of two dengue type-1 isolates reflect modifications of viral structure
    P Despres
    Unité des Arbovirus et Virus des Fièvres Hémorragiques, Institut Pasteur, Paris, France
    Virology 196:209-19. 1993
    ..Changes at positions 96, 297, and 379 map within two overlapping antigenic domains of protein E. These limited amino acid differences in the E protein could affect the biological properties and the antigenicity of the DEN virion...
  9. ncbi request reprint Variations in biological features of West Nile viruses
    V Deubel
    Institut Pasteur, Unité de Biologie des Infections Virales Emergentes, Lyon, France
    Ann N Y Acad Sci 951:195-206. 2001
    ..However, biological and molecular markers of virus virulence should be characterized to assess whether novel strains with increased virulence are responsible for this recent proliferation of outbreaks...
  10. ncbi request reprint Production and characterization of mouse monoclonal antibodies reactive to Chikungunya envelope E2 glycoprotein
    Anne Claire Brehin
    Interactions Moléculaires Flavivirus Hôtes, Institut Pasteur, 75724 Paris, France
    Virology 371:185-95. 2008
    ..Anti-CHIK E2 MAbs 3C3, 3E4, and 8A4 should be helpful for studying the biology of CHIK virus and pathogenesis of disease. The combination of 8A4 and 3E4 is suitable for developing a specific antigen-capture ELISA...
  11. pmc Molecular diagnostic and genetic characterization of highly pathogenic viruses: application during Crimean-Congo haemorrhagic fever virus outbreaks in Eastern Europe and the Middle East
    C Filippone
    Institut Pasteur, Unit of Epidemiology and Pathophysiology of Oncogenic Viruses, Paris, France
    Clin Microbiol Infect 19:E118-28. 2013
    ..0 resequencing microarray to characterize geographical variants in the follow-up of haemorrhagic fever epidemics; to manage patients and protect communities; and in cases of bioterrorism...
  12. pmc A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease
    Thérèse Couderc
    Groupe Microorganismes et Barrières de l Hôte, Institut Pasteur, Paris, France
    PLoS Pathog 4:e29. 2008
    ..The development of a permissive small animal model will expedite the testing of future vaccines and therapeutic candidates...
  13. doi request reprint Resequencing microarray method for molecular diagnosis of human arboviral diseases
    N Berthet
    Institut Pasteur, Epidemiology and Physiopathology of Oncogenic Viruses Unit, 28 rue du Docteur Roux, F75015 Paris, France
    J Clin Virol 56:238-43. 2013
    ..Resequencing DNA microarray (RMA) technology uses probes designed to identify a panel of viral sequences. It can be used for detecting emerging viruses by revealing the nucleotide polymorphisms within the target of interest...
  14. ncbi request reprint A paediatric vaccination vector based on live attenuated measles vaccine
    Clarisse Lorin
    Unite des Virus Lents, CNRS URA 1930, Institut Pasteur, Paris, France
    Therapie 60:227-33. 2005
    ....
  15. ncbi request reprint Dynamics of immune cell recruitment during West Nile encephalitis and identification of a new CD19+B220-BST-2+ leukocyte population
    Anne Claire Brehin
    Neuro Immunologie Virale, Institut Pasteur, Paris, France
    J Immunol 180:6760-7. 2008
    ..G8-ICs express high levels of MHC class II, stain for viral Ag, and are localized in the paracortical zone of lymph nodes, strongly suggesting they are previously unidentified APCs that appear in response to viral infection...
  16. ncbi request reprint The 2',5'-oligoadenylate synthetase 1b is a potent inhibitor of West Nile virus replication inside infected cells
    Anna Kajaste-Rudnitski
    Interactions Moléculaires Flavivirus Hôtes and Génétique des Mammifères, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris, Cedex 15, France
    J Biol Chem 281:4624-37. 2006
    ..Thus, Oas1b represents an antiviral pathway that exerts its inhibitory effect on WNV replication by preventing viral RNA accumulation inside infected cells...
  17. ncbi request reprint Flaviviruses and apoptosis regulation
    A Catteau
    U P Flavivirus Host Molecular Interactions, Virology Department, Pasteur Institute, 25 rue du Dr Roux, 75724 Paris Cedex 15, France
    Prog Mol Subcell Biol 36:171-89. 2004
  18. ncbi request reprint Infection of mouse neurones by West Nile virus is modulated by the interferon-inducible 2'-5' oligoadenylate synthetase 1b protein
    Marianne Lucas
    Unité des Interactions Moléculaires Flavivirus Hôtes, Institut Pasteur, Paris, France
    Immunol Cell Biol 81:230-6. 2003
    ..Our data illustrate the notion that interferon-alpha and Oas genes may be critical for West Nile virus pathogenesis...
  19. doi request reprint Viral determinants in the NS3 helicase and 2K peptide that promote West Nile virus resistance to antiviral action of 2',5'-oligoadenylate synthetase 1b
    Eva Mertens
    Unité Interactions Moléculaires Flavivirus Hôtes, Institut Pasteur, 75724 Paris, France
    Virology 399:176-85. 2010
    ..Thus, WNV resistance to Oas1b antiviral action could be attributed to the 2K-V9M substitution with a potential role of NS3-S365G through rescue of vRNA accumulation...
  20. doi request reprint Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein
    Simona Ozden
    Unité d Epidémiologie et Physiopathologie des Virus Oncogènes, CNRS URA 3015, Institut Pasteur, 75724 Paris, France
    J Biol Chem 283:21899-908. 2008
    ..Our results demonstrate the role of furin-like proteases in the processing of CHIKV particles and point out new approaches to inhibit this infection...
  21. pmc Characterization of reemerging chikungunya virus
    Marion Sourisseau
    Department of Virology, Unité Virus et Immunite, Institut Pasteur, Paris, France
    PLoS Pathog 3:e89. 2007
    ..CHIKV was highly sensitive to the antiviral activity of type I and II interferons. These results provide a general insight into the interaction between CHIKV and its mammalian host...
  22. doi request reprint The large form of human 2',5'-Oligoadenylate Synthetase (OAS3) exerts antiviral effect against Chikungunya virus
    Anne Claire Brehin
    Unité Interactions Moléculaires Flavivirus Hôtes and Centre National de Référence des Arbovirus, Institut Pasteur, Paris, France
    Virology 384:216-22. 2009
    ..HeLa cells expressing the truncated form of OAS3 were less resistant to CHIKV infection, raising the question on the involvement of OAS3 genetic polymorphism in human susceptibility to alphavirus infection...
  23. pmc Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses
    Erika Navarro-Sanchez
    Interactions Moléculaires Flavivirus Hôtes, 25 rue du Dr Roux, 75724 Paris, France
    EMBO Rep 4:723-8. 2003
    ..Mosquito-cell-derived DVs may have differential infectivity for DC-SIGN-expressing cells. We suggest that the differential use of DC-SIGN by viral envelope glycoproteins may account for the immunopathogenesis of DVs...
  24. pmc Human muscle satellite cells as targets of Chikungunya virus infection
    Simona Ozden
    Unité Epidémiologie et Physiopathologie des Virus Oncogènes CNRS URA1930, Institut Pasteur, Paris, France
    PLoS ONE 2:e527. 2007
    ..7% of cases. Since the cellular targets of CHIK virus in humans are unknown, we studied the pathogenic events and targets of CHIK infection in skeletal muscle...
  25. ncbi request reprint Structural and functional genomics and evolutionary relationships in the cluster of genes encoding murine 2',5'-oligoadenylate synthetases
    Tomoji Mashimo
    Unite de Genetique des Mammiferes, Institut Pasteur, 75724 Paris Cedex 15, France
    Genomics 82:537-52. 2003
    ..For all these eight genes a specific inducible promoter controls transcription. The possible functions of this family of proteins are discussed...
  26. ncbi request reprint Expression of dengue ApoptoM sequence results in disruption of mitochondrial potential and caspase activation
    Adeline Catteau
    Unité des Interactions Moléculaires Flavivirus Hôtes, Institut Pasteur, 25, rue du Dr Roux, 75015 Paris, France
    Biochimie 85:789-93. 2003
    ..However, there was no role for caspase-9 in ApoptoM-mediated cell death. Our data suggest that a particular mitochondrion-dependent apoptotic pathway may be involved in induction of apoptosis by ApoptoM...
  27. pmc Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak
    Isabelle Schuffenecker
    Centre National de Référence des Arbovirus, Institut Pasteur, Lyon, France
    PLoS Med 3:e263. 2006
    ..Besides the arthralgic form, 123 patients with a confirmed chikungunya infection have developed severe clinical signs, i.e., neurological signs or fulminant hepatitis...