Claire Desnos

Summary

Affiliation: Institut de Biologie Physico-Chimique
Country: France

Publications

  1. ncbi request reprint 'Should I stay or should I go?': myosin V function in organelle trafficking
    Claire Desnos
    Institut de Biologie Physico Chimique, Centre National de la Recherche Scientifique, UPR 1929, Universite Paris 7 Denis Diderot, Paris, France
    Biol Cell 99:411-23. 2007
  2. ncbi request reprint Myosin va mediates docking of secretory granules at the plasma membrane
    Claire Desnos
    Institut de Biologie Physico Chimique, Centre National de la Recherche Scientifique, Unité Propre de Recherche 1929, Universite Paris 7 Denis Diderot, 75005 Paris, France
    J Neurosci 27:10636-45. 2007
  3. doi request reprint Myrip couples the capture of secretory granules by the actin-rich cell cortex and their attachment to the plasma membrane
    Sebastien Huet
    Centre National de la Recherche Scientifique, UMR 6290, Institut Génétique et Développement de Rennes and Faculté de Médecine, Universite Rennes 1, Universite Europeenne de Bretagne, Fédération de recherche Biosit, F 35043 Rennes, France
    J Neurosci 32:2564-77. 2012
  4. pmc Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites
    Claire Desnos
    Centre National de la Recherche Scientifique CNRS UPR 1929, Institut de Biologie Physico Chimique, 75005 Paris, France
    J Cell Biol 163:559-70. 2003
  5. ncbi request reprint Serotonin secretion by human carcinoid BON cells
    Viet Samuel Tran
    Biologie moléculaire et cellulaire de la secretion, CNRS UPR 1929, Institut de Biologie Physico Chimique, 75005 Paris, France
    Ann N Y Acad Sci 1014:179-88. 2004
  6. ncbi request reprint Transmitter uptake and release in PC12 cells overexpressing plasma membrane monoamine transporters
    Jean Sébastien Schonn
    CNRS UPR 1929, Institut de Biologie Physico Chimique, 13 rue Pierre et Marie Curie, 75005 Paris, France
    J Neurochem 84:669-77. 2003
  7. pmc MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes
    Aziz El-Amraoui
    Unité de Génétique des Déficits Sensoriels, CNRS URA 1968, Institut Pasteur, 25 rue du Dr Roux, F 5724 Paris cedex 15, France
    EMBO Rep 3:463-70. 2002

Collaborators

  • Genevieve De Saint Basile
  • Graca Raposo
  • François Darchen
  • Sebastien Huet
  • Jean Pierre Henry
  • Jean Sébastien Schonn
  • Viet Samuel Tran
  • Aziz El-Amraoui
  • Tim Zeiske
  • Isabelle Fanget
  • Ouardane Jouannot
  • Nathanael Larochette
  • Patricia Meireles
  • Catherine Chapuis
  • Koulm Guillaumie
  • Sophie Cribier
  • Erdem Karatekin
  • Anne Marie Marion-Audibert
  • Stephane Blanchard
  • Uwe Wolfrum
  • Christine Petit
  • Polonca Küssel-Andermann

Detail Information

Publications7

  1. ncbi request reprint 'Should I stay or should I go?': myosin V function in organelle trafficking
    Claire Desnos
    Institut de Biologie Physico Chimique, Centre National de la Recherche Scientifique, UPR 1929, Universite Paris 7 Denis Diderot, Paris, France
    Biol Cell 99:411-23. 2007
    ..These defects probably account for the severe neurological symptoms observed in Griscelli syndrome due to mutations in the MYO5A gene...
  2. ncbi request reprint Myosin va mediates docking of secretory granules at the plasma membrane
    Claire Desnos
    Institut de Biologie Physico Chimique, Centre National de la Recherche Scientifique, Unité Propre de Recherche 1929, Universite Paris 7 Denis Diderot, 75005 Paris, France
    J Neurosci 27:10636-45. 2007
    ..In contrast, MyoVa silencing reduced the occurrence of long-lasting, but not short-lasting, docking periods. We thus propose that, despite its known motor activity, MyoVa directly mediates stable attachment of SGs at the plasma membrane...
  3. doi request reprint Myrip couples the capture of secretory granules by the actin-rich cell cortex and their attachment to the plasma membrane
    Sebastien Huet
    Centre National de la Recherche Scientifique, UMR 6290, Institut Génétique et Développement de Rennes and Faculté de Médecine, Universite Rennes 1, Universite Europeenne de Bretagne, Fédération de recherche Biosit, F 35043 Rennes, France
    J Neurosci 32:2564-77. 2012
    ..We conclude that Myrip couples the retention of SGs in the cell cortex, their transport to the PM, and their attachment to the PM, and thus promotes secretion. These three steps of the secretory process are thus intimately coordinated...
  4. pmc Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites
    Claire Desnos
    Centre National de la Recherche Scientifique CNRS UPR 1929, Institut de Biologie Physico Chimique, 75005 Paris, France
    J Cell Biol 163:559-70. 2003
    ..We propose that Rab27A and MyRIP link SGs to F-actin and control their motion toward release sites through the actin cortex...
  5. ncbi request reprint Serotonin secretion by human carcinoid BON cells
    Viet Samuel Tran
    Biologie moléculaire et cellulaire de la secretion, CNRS UPR 1929, Institut de Biologie Physico Chimique, 75005 Paris, France
    Ann N Y Acad Sci 1014:179-88. 2004
    ..Even in the case of mobile vesicles, exocytosis often was preceded by a period of arrest lasting at least 15 seconds, consistent with a docking/priming step...
  6. ncbi request reprint Transmitter uptake and release in PC12 cells overexpressing plasma membrane monoamine transporters
    Jean Sébastien Schonn
    CNRS UPR 1929, Institut de Biologie Physico Chimique, 13 rue Pierre et Marie Curie, 75005 Paris, France
    J Neurochem 84:669-77. 2003
    ..The co-transfection assay described here, based on transient expression of monoamine transporters, should prove useful in functional studies of the secretory machinery...
  7. pmc MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes
    Aziz El-Amraoui
    Unité de Génétique des Déficits Sensoriels, CNRS URA 1968, Institut Pasteur, 25 rue du Dr Roux, F 5724 Paris cedex 15, France
    EMBO Rep 3:463-70. 2002
    ..The defect of this molecular complex is likely to account for the perinuclear mislocalization of the melanosomes observed in the retinal pigment epithelium cells of myosinVIIa-defective mice...