Claire Desnos

Summary

Affiliation: Institut de Biologie Physico-Chimique
Country: France

Publications

  1. ncbi 'Should I stay or should I go?': myosin V function in organelle trafficking
    Claire Desnos
    Institut de Biologie Physico Chimique, Centre National de la Recherche Scientifique, UPR 1929, Universite Paris 7 Denis Diderot, Paris, France
    Biol Cell 99:411-23. 2007
  2. ncbi Myosin va mediates docking of secretory granules at the plasma membrane
    Claire Desnos
    Institut de Biologie Physico Chimique, Centre National de la Recherche Scientifique, Unité Propre de Recherche 1929, Universite Paris 7 Denis Diderot, 75005 Paris, France
    J Neurosci 27:10636-45. 2007
  3. ncbi Myrip couples the capture of secretory granules by the actin-rich cell cortex and their attachment to the plasma membrane
    Sebastien Huet
    Centre National de la Recherche Scientifique, UMR 6290, Institut Génétique et Développement de Rennes and Faculté de Médecine, Universite Rennes 1, Universite Europeenne de Bretagne, Fédération de recherche Biosit, F 35043 Rennes, France
    J Neurosci 32:2564-77. 2012
  4. ncbi Transmitter uptake and release in PC12 cells overexpressing plasma membrane monoamine transporters
    Jean Sébastien Schonn
    CNRS UPR 1929, Institut de Biologie Physico Chimique, 13 rue Pierre et Marie Curie, 75005 Paris, France
    J Neurochem 84:669-77. 2003
  5. ncbi MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes
    Aziz El-Amraoui
    Unité de Génétique des Déficits Sensoriels, CNRS URA 1968, Institut Pasteur, 25 rue du Dr Roux, F 5724 Paris cedex 15, France
    EMBO Rep 3:463-70. 2002
  6. ncbi Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites
    Claire Desnos
    Centre National de la Recherche Scientifique (CNRS) UPR 1929, Institut de Biologie Physico-Chimique, 75005 Paris, France
    J Cell Biol 163:559-70. 2003

Collaborators

  • Graca Raposo
  • François Darchen
  • Sebastien Huet
  • Jean Sébastien Schonn
  • Jean Pierre Henry
  • Jean-Pierre Henry
  • Aziz El-Amraoui
  • Nathanael Larochette
  • Ouardane Jouannot
  • Patricia Meireles
  • Tim Zeiske
  • Isabelle Fanget
  • Christine Petit
  • Stephane Blanchard
  • Uwe Wolfrum
  • Polonca Küssel-Andermann

Detail Information

Publications6

  1. ncbi 'Should I stay or should I go?': myosin V function in organelle trafficking
    Claire Desnos
    Institut de Biologie Physico Chimique, Centre National de la Recherche Scientifique, UPR 1929, Universite Paris 7 Denis Diderot, Paris, France
    Biol Cell 99:411-23. 2007
    ..These defects probably account for the severe neurological symptoms observed in Griscelli syndrome due to mutations in the MYO5A gene...
  2. ncbi Myosin va mediates docking of secretory granules at the plasma membrane
    Claire Desnos
    Institut de Biologie Physico Chimique, Centre National de la Recherche Scientifique, Unité Propre de Recherche 1929, Universite Paris 7 Denis Diderot, 75005 Paris, France
    J Neurosci 27:10636-45. 2007
    ..In contrast, MyoVa silencing reduced the occurrence of long-lasting, but not short-lasting, docking periods. We thus propose that, despite its known motor activity, MyoVa directly mediates stable attachment of SGs at the plasma membrane...
  3. ncbi Myrip couples the capture of secretory granules by the actin-rich cell cortex and their attachment to the plasma membrane
    Sebastien Huet
    Centre National de la Recherche Scientifique, UMR 6290, Institut Génétique et Développement de Rennes and Faculté de Médecine, Universite Rennes 1, Universite Europeenne de Bretagne, Fédération de recherche Biosit, F 35043 Rennes, France
    J Neurosci 32:2564-77. 2012
    ..We conclude that Myrip couples the retention of SGs in the cell cortex, their transport to the PM, and their attachment to the PM, and thus promotes secretion. These three steps of the secretory process are thus intimately coordinated...
  4. ncbi Transmitter uptake and release in PC12 cells overexpressing plasma membrane monoamine transporters
    Jean Sébastien Schonn
    CNRS UPR 1929, Institut de Biologie Physico Chimique, 13 rue Pierre et Marie Curie, 75005 Paris, France
    J Neurochem 84:669-77. 2003
    ..The co-transfection assay described here, based on transient expression of monoamine transporters, should prove useful in functional studies of the secretory machinery...
  5. ncbi MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes
    Aziz El-Amraoui
    Unité de Génétique des Déficits Sensoriels, CNRS URA 1968, Institut Pasteur, 25 rue du Dr Roux, F 5724 Paris cedex 15, France
    EMBO Rep 3:463-70. 2002
    ..The defect of this molecular complex is likely to account for the perinuclear mislocalization of the melanosomes observed in the retinal pigment epithelium cells of myosinVIIa-defective mice...
  6. ncbi Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites
    Claire Desnos
    Centre National de la Recherche Scientifique (CNRS) UPR 1929, Institut de Biologie Physico-Chimique, 75005 Paris, France
    J Cell Biol 163:559-70. 2003
    ..We propose that Rab27A and MyRIP link SGs to F-actin and control their motion toward release sites through the actin cortex...