L Desjardins

Summary

Affiliation: Institut Curie
Country: France

Publications

  1. pmc Retinoblastoma
    Isabelle Aerts
    Pediatric Oncology Department, Institut Curie, Paris, France
    Orphanet J Rare Dis 1:31. 2006
  2. doi request reprint [Spontaneous subretinal isolated hematomas or associated with macular degeneration: a retrospective review of 95 cases]
    L Desjardins
    Institut Curie, Paris
    J Fr Ophtalmol 32:621-8. 2009
  3. ncbi request reprint Combined proton beam radiotherapy and transpupillary thermotherapy for large uveal melanomas: a randomized study of 151 patients
    L Desjardins
    Institut Curie, Paris, France
    Ophthalmic Res 38:255-60. 2006
  4. doi request reprint [Choroidal nevi]
    L Desjardins
    Institut Curie, 26, rue d Ulm, 75248 Paris Cedex 5
    J Fr Ophtalmol 33:136-41. 2010
  5. ncbi request reprint [Functional results of retinoblastoma treatment with local treatment used in isolation or associated with chemotherapy]
    L Desjardins
    Institut Curie, 26, rue d Ulm, 75005 Paris
    J Fr Ophtalmol 28:725-31. 2005
  6. doi request reprint Treatment of uveal melanoma by accelerated proton beam
    Laurence Desjardins
    Department of Ophthalmology, Institut Curie, Paris, France
    Dev Ophthalmol 49:41-57. 2012
  7. ncbi request reprint 125I plaque brachytherapy for anterior uveal melanomas
    L Lumbroso-Le Rouic
    Department of Ophthalmology, Institut Curie, Paris, France
    Eye (Lond) 18:911-6. 2004
  8. pmc Multiplex PCR/liquid chromatography assay for detection of gene rearrangements: application to RB1 gene
    C Dehainault
    Service de génétique oncologique, Pathologie moléculaire des cancers, Institut Curie, Paris, France
    Nucleic Acids Res 32:e139. 2004
  9. doi request reprint Surgical management of liver metastases from uveal melanoma: 16 years' experience at the Institut Curie
    P Mariani
    Department of Surgery, Institut Curie, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    Eur J Surg Oncol 35:1192-7. 2009
  10. pmc Familial retinoblastoma: fundus screening schedule impact and guideline proposal. A retrospective study
    P R Rothschild
    Department of Ocular Oncology, Institut Curie, Paris, France
    Eye (Lond) 25:1555-61. 2011

Collaborators

Detail Information

Publications32

  1. pmc Retinoblastoma
    Isabelle Aerts
    Pediatric Oncology Department, Institut Curie, Paris, France
    Orphanet J Rare Dis 1:31. 2006
    ..Long term follow-up and early counseling regarding the risk of second primary tumors and transmission should be offered to retinoblastoma patients...
  2. doi request reprint [Spontaneous subretinal isolated hematomas or associated with macular degeneration: a retrospective review of 95 cases]
    L Desjardins
    Institut Curie, Paris
    J Fr Ophtalmol 32:621-8. 2009
    ..In some cases of expansive or posterior lesion, hematoma may be misdiagnosed as a tumor. MRI and color Doppler imaging (CDI) are important in ruling out uveal melanoma in these cases...
  3. ncbi request reprint Combined proton beam radiotherapy and transpupillary thermotherapy for large uveal melanomas: a randomized study of 151 patients
    L Desjardins
    Institut Curie, Paris, France
    Ophthalmic Res 38:255-60. 2006
    ..We conducted a randomized study to determine whether systematic transpupillary thermotherapy (TTT) after proton beam radiotherapy could have a beneficial effect...
  4. doi request reprint [Choroidal nevi]
    L Desjardins
    Institut Curie, 26, rue d Ulm, 75248 Paris Cedex 5
    J Fr Ophtalmol 33:136-41. 2010
    ....
  5. ncbi request reprint [Functional results of retinoblastoma treatment with local treatment used in isolation or associated with chemotherapy]
    L Desjardins
    Institut Curie, 26, rue d Ulm, 75005 Paris
    J Fr Ophtalmol 28:725-31. 2005
    ..Because of long-term complications of external beam radiation in retinoblastoma, a new therapeutic modality using chemotherapy and local treatments is used whenever possible. We conducted a retrospective study to evaluate visual results...
  6. doi request reprint Treatment of uveal melanoma by accelerated proton beam
    Laurence Desjardins
    Department of Ophthalmology, Institut Curie, Paris, France
    Dev Ophthalmol 49:41-57. 2012
    ..Additional treatments after proton beam such as transpupillary thermotherapy, endoresection of the tumor scar or intravitreal injections of anti-VEGF may reduce the rate of these complications...
  7. ncbi request reprint 125I plaque brachytherapy for anterior uveal melanomas
    L Lumbroso-Le Rouic
    Department of Ophthalmology, Institut Curie, Paris, France
    Eye (Lond) 18:911-6. 2004
    ....
  8. pmc Multiplex PCR/liquid chromatography assay for detection of gene rearrangements: application to RB1 gene
    C Dehainault
    Service de génétique oncologique, Pathologie moléculaire des cancers, Institut Curie, Paris, France
    Nucleic Acids Res 32:e139. 2004
    ..MP/LC appears to be an easy, versatile, and cost-effective method, which is particularly relevant to denaturing HPLC (DHPLC) users since it broadens the spectrum of available applications on a DHPLC system...
  9. doi request reprint Surgical management of liver metastases from uveal melanoma: 16 years' experience at the Institut Curie
    P Mariani
    Department of Surgery, Institut Curie, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    Eur J Surg Oncol 35:1192-7. 2009
    ..Uveal melanoma is characterised by a high prevalence of liver metastases and a poor prognosis...
  10. pmc Familial retinoblastoma: fundus screening schedule impact and guideline proposal. A retrospective study
    P R Rothschild
    Department of Ocular Oncology, Institut Curie, Paris, France
    Eye (Lond) 25:1555-61. 2011
    ..To assess if systematic fundus screening according to an 'intensive' schedule alters ocular outcome and to propose fundus screening schedule guidelines for children related to a retinoblastoma patient...
  11. ncbi request reprint [Treatment of uveal melanoma with iodine 125 plaques or proton beam therapy: indications and comparison of local recurrence rates]
    L Desjardins
    Institut Curie, 26, rue d Ulm, 75005 Paris
    J Fr Ophtalmol 26:269-76. 2003
    ..This retrospective study compared the rate of local recurrence after irradiation of uveal melanoma treated with iodine 125 plaques or proton beam therapy...
  12. ncbi request reprint [Diode laser thermotherapy and chemothermotherapy in the treatment of retinoblastoma]
    L Lumbroso
    Service d Ophtalmologie, Institut Curie, Paris
    J Fr Ophtalmol 26:154-9. 2003
    ..We present our experience with thermotherapy in the treatment of selected cases of retinoblastoma...
  13. pmc Intraocular inflammation after proton beam irradiation for uveal melanoma
    L Lumbroso
    Department of Ophthalmology, Institut Curie, 26 rue d'Ulm, 75005 Paris, France
    Br J Ophthalmol 85:1305-8. 2001
    ..CONCLUSION: Inflammation following proton beam irradiation is not unusual. It is correlated with larger initial tumours and may be related to tumour necrosis...
  14. ncbi request reprint Proton beam therapy for iris melanomas
    L Lumbroso-Le Rouic
    Department of Ophthalmology, Institut Curie, Paris, France livia lumbroso curie net
    Eye (Lond) 20:1300-5. 2006
    ..To describe the results in terms of local control, eye preservation and systemic evolution of iris melanomas treated by proton beam irradiation...
  15. ncbi request reprint [Results of treating uveal melanoma with proton beam radiation: 10-year follow-up]
    Z Hamrouni
    Service d Ophtalmologie, Institut Curie, Paris
    J Fr Ophtalmol 28:833-9. 2005
    ..We analyzed the long-term results of uveal melanoma treatment with proton beam irradiation in a series of patients with a follow-up of at least 10 years...
  16. ncbi request reprint [Cured after an intraocular tumor]
    L Desjardins
    Institut Curie, 26, rue d'Ulm, 75005 Paris
    Bull Cancer 88:1069-74. 2001
    ..For retinoblastoma we describe the treatments and results with the risk of second cancer, the follow-up of the patients, the psychological problems for parents and children and the specificity of the familial cases...
  17. doi request reprint Preoperative staging of liver metastases from uveal melanoma by magnetic resonance imaging (MRI) and fluorodeoxyglucose-positron emission tomography (FDG-PET)
    V Servois
    Department of Radiology and Nuclear Medicine, Institut Curie, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    Eur J Surg Oncol 36:189-94. 2010
    ....
  18. doi request reprint Contribution of CDKN2A/P16 ( INK4A ), P14 (ARF), CDK4 and BRCA1/2 germline mutations in individuals with suspected genetic predisposition to uveal melanoma
    B Buecher
    Service de génétique oncologique, Institut Curie, 26, rue d Ulm, 75248 Paris Cedex 05, France
    Fam Cancer 9:663-7. 2010
    ..International studies are ongoing in melanoma-prone families in an attempt to identify uveal melanoma susceptibility loci and genes...
  19. ncbi request reprint [Differential diagnosis of retinoblastoma: a retrospective study of 486 cases]
    A Vahedi
    Institut Curie, Paris
    J Fr Ophtalmol 31:165-72. 2008
    ..Detail the most frequent problems encountered in the differential diagnosis of retinoblastoma...
  20. doi request reprint [Protontherapy: basis, indications and new technologies]
    A Mazal
    Institut Curie, Paris, France
    Bull Cancer 97:831-46. 2010
    ....
  21. ncbi request reprint [Risk factors for the degeneration of the choroid naevi: a retrospective study of 135 cases]
    L Desjardins
    Service d'Ophtalmologie, Institut Curie, 26, rue d'Ulm, 75005 Paris, France
    J Fr Ophtalmol 24:610-6. 2001
    ..CONCLUSION: It is important to determine if a choroidal naevus is suspicious or benign and to propose closer follow-up for suspicious lesions...
  22. ncbi request reprint [Bilateral uveal melanomas. Five case reports]
    L Bhouri
    Service d Ophtalmologie, Institut Curie, Paris
    J Fr Ophtalmol 26:149-53. 2003
    ..The occurrence of bilateral uveal melanoma is an extremely rare event, but the observed frequency is nevertheless higher than what can be attributed to chance. Possible responsible factors may include a genetic predisposition...
  23. ncbi request reprint [Cavitary choroidal melanoma in a child]
    H Faraj
    Service d Ophtalmologie, Institut Curie, Paris, France
    J Fr Ophtalmol 29:559-63. 2006
    ..The patient was treated by enucleation and the pathology confirmed the diagnosis of choroidal melanoma. FISH revealed no aberration in chromosome 3...
  24. ncbi request reprint [Prognostic factors for malignant uveal melanoma. Retrospective study on 2,241 patients and recent contribution of monosomy-3 research]
    L Desjardins
    Service d Oncologie Oculaire, Institut Curie, Paris
    J Fr Ophtalmol 29:741-9. 2006
    ..We conducted a retrospective study on the clinical factors influencing the local and general prognosis of patients treated for uveal melanoma with a preliminary analysis of the prognostic value of monosomy 3...
  25. doi request reprint Uveal metastasis revealing lung cancer
    L Meziani
    Service d Ophtalmologie, Institut Curie, 26, rue d Ulm Paris, 75005 Paris, France
    J Fr Ophtalmol 35:420-5. 2012
    ....
  26. ncbi request reprint Osteosarcoma following retinoblastoma: age at onset and latency period
    L Chauveinc
    Departement de Radiotherapie, Institut Curie, Paris, France
    Ophthalmic Genet 22:77-88. 2001
    ..A radiation-induced mutation of the second RB1 allele may be the cause of osteosarcomas occurring after a short delay, while other genes may be affected in those occurring after a longer delay...
  27. pmc Choroidal and adnexal extranodal marginal zone B-cell lymphoma: presentation, imaging findings, and therapeutic management in a series of nine cases
    P Loriaut
    Department of Ophthalmology, Pitie Salpetriere Hospital, Paris, France
    Eye (Lond) 27:828-35. 2013
    ..To describe the clinical and imaging presentation, pitfalls in the diagnosis of choroidal extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT), as well as the therapeutic management and prognosis...
  28. ncbi request reprint [Radiotherapy in the treatment of eyelid tumors]
    L Desjardins
    Service d Ophtalmologie, Institut Curie, 26, rue d Ulm, 75005 Paris
    J Fr Ophtalmol 26:84-7. 2003
    ..The most frequent indications for radiation in the management of these tumors are also reviewed...
  29. pmc Neoadjuvant chemotherapy for extensive unilateral retinoblastoma
    E Bellaton
    Institut Curie, Paris, France
    Br J Ophthalmol 87:327-9. 2003
    ..The role of neoadjuvant chemotherapy was studied when first line enucleation cannot be safely performed in unilateral extensive retinoblastoma (major buphthalmia or radiologically detectable optic nerve involvement)...
  30. ncbi request reprint Comprehensive screening for constitutional RB1 mutations by DHPLC and QMPSF
    C Houdayer
    Service de génétique oncologique, Institut Curie, Paris, France
    Hum Mutat 23:193-202. 2004
    ..Finally, considering the benefits to retinoblastoma patients, RB1 testing should be widely implemented in routine healthcare because our study clearly illustrates its feasibility...
  31. ncbi request reprint [Benign pigmented lesions of the eyelids]
    L Desjardins
    Service d Ophtalmologie, Institut Curie, 26, rue d Ulm, 75248 Paris Cedex 05
    J Fr Ophtalmol 28:889-95. 2005
    ..For each of these lesions, we describe the clinical and histopathological aspect as well as the therapeutic guidelines...
  32. ncbi request reprint [Radiation-induced retinopathy]
    L Lumbroso
    Service d Ophtalmologie, Institut Curie, 26, rue d Ulm, 75248, Paris, France
    Cancer Radiother 6:289-95. 2002
    ..Patients who underwent an irradiation near the eye (skull base tumors, nasal and paranasal tumors, or brain tumors) should be followed by periodic ophthalmologic examination to detect and treat when necessary the non perfusion areas...