Laurent Debarbieux

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. doi request reprint Bacteriophages can treat and prevent Pseudomonas aeruginosa lung infections
    Laurent Debarbieux
    Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Institut Pasteur, 75724 Paris, France
    J Infect Dis 201:1096-104. 2010
  2. doi request reprint Bacterial sensing of bacteriophages in communities: the search for the Rosetta stone
    Laurent Debarbieux
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, F 75015 Paris, France Electronic address
    Curr Opin Microbiol 20:125-30. 2014
  3. doi request reprint [Phagotherapy: a nightmare for bacteria, a dream for physicians?]
    Laurent Debarbieux
    Institut Pasteur, Departement de Microbiologie, 25 rue du Dr Roux, 75724 Paris Cedex 15, France
    Biol Aujourdhui 207:181-90. 2013
  4. pmc Virulent bacteriophages can target O104:H4 enteroaggregative Escherichia coli in the mouse intestine
    Damien Maura
    Department of Microbiology, Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Paris, France
    Antimicrob Agents Chemother 56:6235-42. 2012
  5. doi request reprint Bacteriophages in the experimental treatment of Pseudomonas aeruginosa infections in mice
    Emilie Saussereau
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Paris, France
    Adv Virus Res 83:123-41. 2012
  6. pmc Pulmonary bacteriophage therapy on Pseudomonas aeruginosa cystic fibrosis strains: first steps towards treatment and prevention
    Eric Morello
    Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Institut Pasteur, Paris, France
    PLoS ONE 6:e16963. 2011
  7. doi request reprint Intestinal colonization by enteroaggregative Escherichia coli supports long-term bacteriophage replication in mice
    Damien Maura
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, F 75015 Paris, France
    Environ Microbiol 14:1844-54. 2012
  8. pmc The search for therapeutic bacteriophages uncovers one new subfamily and two new genera of Pseudomonas-infecting Myoviridae
    Marine Henry
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Paris, France
    PLoS ONE 10:e0117163. 2015
  9. doi request reprint Bacteriophages as twenty-first century antibacterial tools for food and medicine
    Damien Maura
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, 75015 Paris, France
    Appl Microbiol Biotechnol 90:851-9. 2011
  10. doi request reprint Tools from viruses: bacteriophage successes and beyond
    Marine Henry
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, F 75015 Paris, France
    Virology 434:151-61. 2012

Collaborators

Detail Information

Publications13

  1. doi request reprint Bacteriophages can treat and prevent Pseudomonas aeruginosa lung infections
    Laurent Debarbieux
    Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Institut Pasteur, 75724 Paris, France
    J Infect Dis 201:1096-104. 2010
    ....
  2. doi request reprint Bacterial sensing of bacteriophages in communities: the search for the Rosetta stone
    Laurent Debarbieux
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, F 75015 Paris, France Electronic address
    Curr Opin Microbiol 20:125-30. 2014
    ..The next challenge will be determining how the dialog between microbial viruses and their hosts modulates complex ecosystems, such as those found in healthy humans or infected patients. ..
  3. doi request reprint [Phagotherapy: a nightmare for bacteria, a dream for physicians?]
    Laurent Debarbieux
    Institut Pasteur, Departement de Microbiologie, 25 rue du Dr Roux, 75724 Paris Cedex 15, France
    Biol Aujourdhui 207:181-90. 2013
    ..Taking two examples of recently published experimental phage therapy results, this article summarizes the hopes but also the challenges that surround the future development of human phage therapy. ..
  4. pmc Virulent bacteriophages can target O104:H4 enteroaggregative Escherichia coli in the mouse intestine
    Damien Maura
    Department of Microbiology, Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Paris, France
    Antimicrob Agents Chemother 56:6235-42. 2012
    ....
  5. doi request reprint Bacteriophages in the experimental treatment of Pseudomonas aeruginosa infections in mice
    Emilie Saussereau
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Paris, France
    Adv Virus Res 83:123-41. 2012
    ..aeruginosa strains. Together with experimental models, these results provide an incentive to develop more research and clinical studies to fully appreciate the benefits of the use of bacteriophages in medicine...
  6. pmc Pulmonary bacteriophage therapy on Pseudomonas aeruginosa cystic fibrosis strains: first steps towards treatment and prevention
    Eric Morello
    Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Institut Pasteur, Paris, France
    PLoS ONE 6:e16963. 2011
    ..aeruginosa cystic fibrosis strains. This work provides an incentive to develop clinical studies on pulmonary bacteriophage therapy to combat multidrug-resistant lung infections...
  7. doi request reprint Intestinal colonization by enteroaggregative Escherichia coli supports long-term bacteriophage replication in mice
    Damien Maura
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, F 75015 Paris, France
    Environ Microbiol 14:1844-54. 2012
    ..This model of stable and continuous viral replication provides opportunities for studying the long-term coevolution of virulent bacteriophages with their hosts within a mammalian polymicrobial ecosystem...
  8. pmc The search for therapeutic bacteriophages uncovers one new subfamily and two new genera of Pseudomonas-infecting Myoviridae
    Marine Henry
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Paris, France
    PLoS ONE 10:e0117163. 2015
    ....
  9. doi request reprint Bacteriophages as twenty-first century antibacterial tools for food and medicine
    Damien Maura
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, 75015 Paris, France
    Appl Microbiol Biotechnol 90:851-9. 2011
    ..Bacteriophages have co-evolved with bacteria for billions of years and retain the ability to infect bacteria efficiently. They are undoubtedly one of the best potential sources of new solutions for the management of undesirable bacteria...
  10. doi request reprint Tools from viruses: bacteriophage successes and beyond
    Marine Henry
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, F 75015 Paris, France
    Virology 434:151-61. 2012
    ....
  11. pmc Predicting in vivo efficacy of therapeutic bacteriophages used to treat pulmonary infections
    Marine Henry
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Paris, France
    Antimicrob Agents Chemother 57:5961-8. 2013
    ..Our results showed that the bacteriophages isolated directly on the targeted host were the most efficient in vivo, supporting a personalized approach favoring an optimal treatment. ..
  12. pmc Characterization of nasal potential difference in cftr knockout and F508del-CFTR mice
    Emilie Lyne Saussereau
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Paris, France
    PLoS ONE 8:e57317. 2013
    ..The use of nasal potential difference (V(TE)) to assess ionic transport is a powerful test evaluating the restoration of CFTR function. Nasal V(TE) in CF mice must be well characterized for correct interpretation...