Laurent Debarbieux

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. doi request reprint Bacteriophages can treat and prevent Pseudomonas aeruginosa lung infections
    Laurent Debarbieux
    Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Institut Pasteur, 75724 Paris, France
    J Infect Dis 201:1096-104. 2010
  2. pmc Pulmonary bacteriophage therapy on Pseudomonas aeruginosa cystic fibrosis strains: first steps towards treatment and prevention
    Eric Morello
    Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Institut Pasteur, Paris, France
    PLoS ONE 6:e16963. 2011
  3. pmc Virulent bacteriophages can target O104:H4 enteroaggregative Escherichia coli in the mouse intestine
    Damien Maura
    Department of Microbiology, Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Paris, France
    Antimicrob Agents Chemother 56:6235-42. 2012
  4. doi request reprint Bacteriophages in the experimental treatment of Pseudomonas aeruginosa infections in mice
    Emilie Saussereau
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Paris, France
    Adv Virus Res 83:123-41. 2012
  5. doi request reprint Intestinal colonization by enteroaggregative Escherichia coli supports long-term bacteriophage replication in mice
    Damien Maura
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, F 75015 Paris, France
    Environ Microbiol 14:1844-54. 2012
  6. doi request reprint [Phagotherapy: a nightmare for bacteria, a dream for physicians?]
    Laurent Debarbieux
    Institut Pasteur, Departement de Microbiologie, 25 rue du Dr Roux, 75724 Paris Cedex 15, France
    Biol Aujourdhui 207:181-90. 2013
  7. doi request reprint Tools from viruses: bacteriophage successes and beyond
    Marine Henry
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, F 75015 Paris, France
    Virology 434:151-61. 2012
  8. doi request reprint Bacteriophages as twenty-first century antibacterial tools for food and medicine
    Damien Maura
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, 75015 Paris, France
    Appl Microbiol Biotechnol 90:851-9. 2011
  9. pmc Predicting in vivo efficacy of therapeutic bacteriophages used to treat pulmonary infections
    Marine Henry
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Paris, France
    Antimicrob Agents Chemother 57:5961-8. 2013
  10. pmc Characterization of nasal potential difference in cftr knockout and F508del-CFTR mice
    Emilie Lyne Saussereau
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Paris, France
    PLoS ONE 8:e57317. 2013

Collaborators

Detail Information

Publications11

  1. doi request reprint Bacteriophages can treat and prevent Pseudomonas aeruginosa lung infections
    Laurent Debarbieux
    Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Institut Pasteur, 75724 Paris, France
    J Infect Dis 201:1096-104. 2010
    ....
  2. pmc Pulmonary bacteriophage therapy on Pseudomonas aeruginosa cystic fibrosis strains: first steps towards treatment and prevention
    Eric Morello
    Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Institut Pasteur, Paris, France
    PLoS ONE 6:e16963. 2011
    ..aeruginosa cystic fibrosis strains. This work provides an incentive to develop clinical studies on pulmonary bacteriophage therapy to combat multidrug-resistant lung infections...
  3. pmc Virulent bacteriophages can target O104:H4 enteroaggregative Escherichia coli in the mouse intestine
    Damien Maura
    Department of Microbiology, Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Paris, France
    Antimicrob Agents Chemother 56:6235-42. 2012
    ....
  4. doi request reprint Bacteriophages in the experimental treatment of Pseudomonas aeruginosa infections in mice
    Emilie Saussereau
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Paris, France
    Adv Virus Res 83:123-41. 2012
    ..aeruginosa strains. Together with experimental models, these results provide an incentive to develop more research and clinical studies to fully appreciate the benefits of the use of bacteriophages in medicine...
  5. doi request reprint Intestinal colonization by enteroaggregative Escherichia coli supports long-term bacteriophage replication in mice
    Damien Maura
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, F 75015 Paris, France
    Environ Microbiol 14:1844-54. 2012
    ..This model of stable and continuous viral replication provides opportunities for studying the long-term coevolution of virulent bacteriophages with their hosts within a mammalian polymicrobial ecosystem...
  6. doi request reprint [Phagotherapy: a nightmare for bacteria, a dream for physicians?]
    Laurent Debarbieux
    Institut Pasteur, Departement de Microbiologie, 25 rue du Dr Roux, 75724 Paris Cedex 15, France
    Biol Aujourdhui 207:181-90. 2013
    ..Taking two examples of recently published experimental phage therapy results, this article summarizes the hopes but also the challenges that surround the future development of human phage therapy. ..
  7. doi request reprint Tools from viruses: bacteriophage successes and beyond
    Marine Henry
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, F 75015 Paris, France
    Virology 434:151-61. 2012
    ....
  8. doi request reprint Bacteriophages as twenty-first century antibacterial tools for food and medicine
    Damien Maura
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, 75015 Paris, France
    Appl Microbiol Biotechnol 90:851-9. 2011
    ..Bacteriophages have co-evolved with bacteria for billions of years and retain the ability to infect bacteria efficiently. They are undoubtedly one of the best potential sources of new solutions for the management of undesirable bacteria...
  9. pmc Predicting in vivo efficacy of therapeutic bacteriophages used to treat pulmonary infections
    Marine Henry
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Paris, France
    Antimicrob Agents Chemother 57:5961-8. 2013
    ..Our results showed that the bacteriophages isolated directly on the targeted host were the most efficient in vivo, supporting a personalized approach favoring an optimal treatment. ..
  10. pmc Characterization of nasal potential difference in cftr knockout and F508del-CFTR mice
    Emilie Lyne Saussereau
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Department of Microbiology, Paris, France
    PLoS ONE 8:e57317. 2013
    ..The use of nasal potential difference (V(TE)) to assess ionic transport is a powerful test evaluating the restoration of CFTR function. Nasal V(TE) in CF mice must be well characterized for correct interpretation...