Research Topics
Species | Isabelle de MascarelSummaryAffiliation: Institut Bergoni Country: France Publications
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Detail Information
Publications
Identification of typical medullary breast carcinoma as a genomic sub-group of basal-like carcinomas, a heterogeneous new molecular entityAnne Vincent-Salomon
Department of Tumor Biology, Institut Curie, Paris Cedex 05, France
Breast Cancer Res 9:R24. 2007..The present study was therefore designed to identify phenotypic and genetic alterations that distinguish MBCs from basal-like carcinomas (BLC)...
Breast ductal carcinoma in situ with microinvasion: a definition supported by a long-term study of 1248 serially sectioned ductal carcinomasIsabelle de Mascarel
Department of Pathology, Institut Bergonie, Regional Cancer Center, Bordeaux, France
Cancer 94:2134-42. 2002..With this definition, the authors attempted to evaluate the clinical significance of microinvasion...
All atypia diagnosed at stereotactic vacuum-assisted breast biopsy do not need surgical excisionIsabelle de Mascarel
Department of Pathology, Comprehensive Cancer Center, Bordeaux, France
Mod Pathol 24:1198-206. 2011..With experienced senologists and strict histological criteria, some patients could be spared surgery resulting in significant patient, financial and time advantages...- D2-40 in breast cancer: should we detect more vascular emboli?Isabelle de Mascarel
Department of Pathology, Institut Bergonie, Regional Cancer Center, Bordeaux, France
Mod Pathol 22:216-22. 2009..Nevertheless, only distant D2-40+ emboli had a prognostic impact. In practice, D2-40 might be useful to detect missed hematoxylin-eosin emboli especially in cases without any other prognostically unfavorable criterion... - Distinction between isolated tumor cells and micrometastases in breast cancer: is it reliable and useful?Isabelle de Mascarel
Department of Pathology, Institute Bergonie, Bordeaux, France
Cancer 112:1672-8. 2008..The authors assessed differences in classifying patients according to the American Joint Commission on Cancer (AJCC) and the International Union Against Cancer (UICC) definitions and method of sizing... - [Management of breast epithelial atypia]Isabelle de Mascarel
Departement de Pathologie, Institut Bergonie, 229 Cours de l Argonne, 33076 Bordeaux Cedex
Ann Pathol 27:182-94. 2007..Indeed, epithelial atypia could be more a risk marker of concomitant than subsequent cancer... 
Epithelial atypia in biopsies performed for microcalcifications. practical considerations about 2,833 serially sectioned surgical biopsies with a long follow-upIsabelle de Mascarel
Department of Pathology, Institut Bergonie, Regional Cancer Center, Bordeaux, France
Virchows Arch 451:1-10. 2007..Epithelial atypia could be more a risk marker of concomitant than subsequent cancer...- Prognostic significance of immunohistochemically detected breast cancer node metastases in 218 patientsI de Mascarel
Department of Pathology, Institut Bergonie, Comprehensive Cancer Center, 180 rue de Saint Genès, 33076 Bordeaux Cedex, France
Br J Cancer 87:70-4. 2002..Moreover, their pejorative significance in the literature is debatable since the groups and events taken into account are heterogeneous... - Immunohistochemically detected lymph node metastases from breast carcinoma: practical considerations about the new American Joint Committee on Cancer classificationIsabelle de Mascarel
Department of Pathology, Institut Bergonie, Bordeaux France
Cancer 103:1319-22. 2005..The authors applied the sixth edition of the American Joint Committee on Cancer (AJCC) classification system to their previously published group of patients with breast carcinoma who had immunohistochemically detected lymph node metastases... - Is it useful to detect lymphovascular invasion in lymph node-positive patients with primary operable breast cancer?Florence Ragage
Department of Pathology, Bergonie Institute, Regional Cancer Center, Bordeaux Cedex, France
Cancer 116:3093-101. 2010..Lymphovascular invasion (LVI) is a widely recognized prognostic factor in lymph node-negative breast cancers. However, there are only limited and controversial data about its prognostic significance in lymph node-positive patients... - Mammography of ductal carcinoma in situ of the breast: review of 909 cases with radiographic-pathologic correlationsBéatrice Barreau
Department of Radiology, Institut Bergonie, Regional Cancer Center, 229, cours de l Argonne, 33076 Bordeaux Cedex, France
Eur J Radiol 54:55-61. 2005..Mammographic size was correlated to histologic size. Masses were correlated with grade 1. A diagnosis strategy can be proposed with a multidisciplinar approach... - Phase III randomized equivalence trial of early breast cancer treatments with or without axillary clearance in post-menopausal patients results after 5 years of follow-upA Avril
Department of Surgery, Institut Bergonie, 229 Cours de l Argonne, 33076 Bordeaux Cedex, France
Eur J Surg Oncol 37:563-70. 2011.... - Ductal carcinoma in situ of the breast: influence of age on diagnostic, therapeutic, and prognostic features. Retrospective study of 812 patientsChristine Tunon-de-Lara
Department of Surgery, Institut Bergonie, Bordeaux Cedex, France
Ann Surg Oncol 18:1372-9. 2011..The objective of this retrospective study was to identify prognostic, diagnostic, and therapeutic disparities between younger (≤ 40 years) and older (> 40 years) women with ductal carcinoma in situ (DCIS) of the breast... - Prediction of HER2 gene status in Her2 2+ invasive breast cancer: a study of 108 cases comparing ASCO/CAP and FDA recommendationsFrederic Chibon
Department of Pathology, Institut Bergonie, Bordeaux, France
Mod Pathol 22:403-9. 2009..Pathological factors, in particular SBR grade 3 and more than 60% Her2+ cells, were significantly correlated with HER2 amplification... - [Diagnostic approach to breast papillary lesions]Gaetan MacGrogan
Departement de Pathologie, Institut Bergonie, Bordeaux
Ann Pathol 23:601-10. 2003.... - Nucleic acid quality preservation by an alcohol-based fixative: comparison with frozen tumors in a routine pathology settingIsabelle Hostein
Department of Pathology, Institut Bergonie, Bordeaux, France
Diagn Mol Pathol 20:52-62. 2011..Tissue fixation with the MF is an important improvement for molecular pathologic diagnosis, enabling a combination of routine pathologic diagnoses and current molecular diagnoses if they are carried out near the processing time... - An array CGH based genomic instability index (G2I) is predictive of clinical outcome in breast cancer and reveals a subset of tumors without lymph node involvement but with poor prognosisFrançoise Bonnet
Inserm U 916 Institut Bergonié, Universite de Bordeaux, Bordeaux, France
BMC Med Genomics 5:54. 2012..abstract:.. - [Digitalized imaging pathology: application to quality control in cancer diagnosis]Celine Merino
Departement de Pathologie, Institut Bergonie, 229 Cours de l Argonne, 33076 Bordeaux
Ann Pathol 25:18-24. 2005..To test a double histology reading system based on digitalized imaging for cancer diagnosis... - Molecular apocrine differentiation is a common feature of breast cancer in patients with germline PTEN mutationsGuillaume Banneau
INSERM U916, Universite de Bordeaux, Institut Bergonie, 229 Cours de l Argonne, 33000, Bordeaux, France
Breast Cancer Res 12:R63. 2010..The absence of known histological features for breast cancer arising in a PTEN-mutant background prompted us to explore them for potential new markers...