Research Topics
Species | Bruno P CoudertSummaryAffiliation: Institut Paoli-Calmettes Country: France Publications
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Detail Information
Publications
Multicenter phase II trial of neoadjuvant therapy with trastuzumab, docetaxel, and carboplatin for human epidermal growth factor receptor-2-overexpressing stage II or III breast cancer: results of the GETN(A)-1 trialBruno P Coudert
Department of Oncology, CAC G F Leclerc and IFR 100, Dijon, France
J Clin Oncol 25:2678-84. 2007..Trastuzumab-based preoperative systemic therapy (PST; neoadjuvant therapy) also appears promising, warranting further investigation...
Pre-operative systemic (neo-adjuvant) therapy with trastuzumab and docetaxel for HER2-overexpressing stage II or III breast cancer: results of a multicenter phase II trialB P Coudert
Oncology, Surgery, Radiology CAC GF Leclerc, Dijon, France
Ann Oncol 17:409-14. 2006..Trastuzumab-based pre-operative systemic (neo-adjuvant) therapy (PST) also appears promising, warranting further investigation...
It is time for chronotherapy!B Coudert
Centre Georges Francois Leclerc, 1, rue du Professeur Marion, BP 77980, 21079 cedex, Dijon, France
Pathol Biol (Paris) 51:197-200. 2003....
Phase II trial with ISIS 5132 in patients with small-cell (SCLC) and non-small cell (NSCLC) lung cancer. A European Organization for Research and Treatment of Cancer (EORTC) Early Clinical Studies Group reportB Coudert
Centre GF Leclerc BP 77980, 21079 Dijon Cedex, France
Eur J Cancer 37:2194-8. 2001....
It's time for chronotherapy!B Coudert
Centre Georges Francois Leclerc, 1 rue du Professeur Marion, BP 77980, 21079, Dijon Cedex, France
Eur J Cancer 38:S50-3. 2002....
Pathologic complete response to trastuzumab-based neoadjuvant therapy is related to the level of HER-2 amplificationLaurent Arnould
CLCC G F Leclerc and 1FR100, Dijon, France
Clin Cancer Res 13:6404-9. 2007..Using FISH and IHC, we analyzed the relationship between pathologic complete response to trastuzumab-based neoadjuvant therapy and level of HER-2 amplification in locally advanced breast cancer...
Gene expression profile and response to trastuzumab-docetaxel-based treatment in breast carcinomaF Vegran
Centre Georges Francois Leclerc, IFR Santé STIC, Dijon Cedex, France
Br J Cancer 101:1357-64. 2009..We examined the ability of microarray analyses to determine the potential markers of pathological complete response (pCR)...
Glutathione S-transferase M1 null genotype: lack of association with tumour characteristics and survival in advanced breast cancerS Lizard-Nacol
Laboratory of Molecular Genetics, Centre Georges Francois Leclerc, 1 rue du Professeur Marion, 21034 Dijon Cedex, France
Breast Cancer Res 1:81-7. 1999..Furthermore, a GSTM1 isoenzyme has been positively associated with protective effect against mutagenic drugs, such as alkylating agents and anthracyclines...
Novel tubulin-targeting agents: anticancer activity and pharmacologic profile of epothilones and related analoguesP Fumoleau
Medical Oncology Department, Centre Georges Francois Leclerc, Dijon, France
Ann Oncol 18:v9-15. 2007....
MDR1 and thymidylate synthase (TS) gene expressions in advanced breast cancer: relationships to drug exposure, p53 mutations, and clinical outcome of the patientsS Lizard-Nacol
Centre Georges Francois Leclerc, Dijon, France
Anticancer Res 19:3575-81. 1999....
Trastuzumab-based treatment of HER2-positive breast cancer: an antibody-dependent cellular cytotoxicity mechanism?L Arnould
Department of Pathology, Centre G F Leclerc, Dijon 21000, France
Br J Cancer 94:259-67. 2006..These results suggest that trastuzumab plus taxanes lead to enhanced NK cell activity, which may partially account for the synergistic activity of trastuzumab and docetaxel in breast cancer...
Sequential two-line strategy for stage IV non-small-cell lung cancer: docetaxel-cisplatin versus vinorelbine-cisplatin followed by cross-over to single-agent docetaxel or vinorelbine at progression: final results of a randomised phase II studyJ Y Douillard
Centre Rene Gauducheau, Saint Herblain, France
Ann Oncol 16:81-9. 2005..This phase II trial compared docetaxel-cisplatin (DC) with vinorelbine-cisplatin (VC), both as first-line therapy followed by cross-over at progression to single-agent vinorelbine or docetaxel in advanced non-small-cell lung cancer (NSCLC)...
Pathological complete response and survival according to the level of HER-2 amplification after trastuzumab-based neoadjuvant therapy for breast cancerS Guiu
Department of Oncology, Georges Francois Leclerc Cancer Center, F 21000 Dijon, France
Br J Cancer 103:1335-42. 2010....
Circadian concepts in normal and neoplastic breastB Coudert
, Dijon, France
Chronobiol Int 19:221-35. 2002....
Hepatic arterial infusion of cisplatin diluted in hypotonic 25 g/l glucose solution administered in balloon-occluded hepatic artery: experimental rationale and clinical pilot studyN Isambert
Dept. of Medical Oncology, , Dijon, France
J Exp Clin Cancer Res 20:183-8. 2001..Total dose of cisplatin in hypotonic glucose solution will not exceed 80 mg by cure in a further phase II study...
Amiodarone is more efficient than verapamil in reversing resistance to anthracyclines in tumour cellsB Chauffert
INSERM, Unite 252, Faculty of Medicine, Dijon, France
Br J Cancer 56:119-22. 1987..We suggest that amiodarone, which is more efficient and less toxic than verapamil, could be substituted for verapamil in future clinical trials...
