Laura Corbo

Summary

Affiliation: Institut Paoli-Calmettes
Country: France

Publications

  1. doi Regulation of estrogen rapid signaling through arginine methylation by PRMT1
    Muriel Le Romancer
    INSERM, U590, Lyon F 69008, France Université de Lyon, Lyon 1, ISPB and IFR62, Lyon F 69003, France
    Mol Cell 31:212-21. 2008
  2. doi Cracking the estrogen receptor's posttranslational code in breast tumors
    Muriel Le Romancer
    Universite de Lyon, Centre de Recherche en Cancérologie de Lyon, Centre Leon Berard, bâtiment Cheney D, 28 rue Laennec, 69373 Lyon Cedex 08, France
    Endocr Rev 32:597-622. 2011
  3. ncbi hCAF1, a new regulator of PRMT1-dependent arginine methylation
    Yannis Robin-Lespinasse
    Inserm Unit U590, Centre Leon Berard, 28 rue Laennec, 69373 Lyon Cedex 08, France and Université Claude Bernard Lyon 1, Lyon, France
    J Cell Sci 120:638-47. 2007
  4. pmc Activation of rapid oestrogen signalling in aggressive human breast cancers
    Coralie Poulard
    Universite de Lyon, France
    EMBO Mol Med 4:1200-13. 2012
  5. doi [Post-translational modifications modulate estrogen receptor alpha activity in breast tumors]
    Coralie Poulard
    Equipe labélisée Ligue contre le cancer, INSERM U590, Centre Leon Berard, bâtiment Cheney D, Lyon F 69008, France
    Med Sci (Paris) 26:636-40. 2010
  6. ncbi Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity
    Stephanie Sentis
    Institut National de la Sante et de la Recherche Medicale, Unité 590, Centre Leon Berard, 28 rue Laennec, 69373 Lyon Cedex 08, France
    Mol Endocrinol 19:2671-84. 2005
  7. ncbi BTG2 antiproliferative protein interacts with the human CCR4 complex existing in vivo in three cell-cycle-regulated forms
    Anne Pierre Morel
    Unité INSERM U590, Centre Leon Berard, 69373 Lyon Cedex 08, France
    J Cell Sci 116:2929-36. 2003
  8. ncbi Identification of NF-kappaB responsive elements in follistatin related gene (FLRG) promoter
    Laurent Bartholin
    INSERM, U590, IFR62, Lyon, F 69008, France
    Gene 393:153-62. 2007
  9. pmc JMJD6 regulates ERα methylation on arginine
    Coralie Poulard
    Universite de Lyon, F 69000 Lyon, France Université Lyon 1, F 69000 Lyon, France INSERM U1052, Centre de Recherche en Cancérologie de Lyon, F 69000 Lyon, France CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, F 69000 Lyon, France Equipe Labellisée La Ligue
    PLoS ONE 9:e87982. 2014
  10. ncbi Transcription activation of FLRG and follistatin by activin A, through Smad proteins, participates in a negative feedback loop to modulate activin A function
    Laurent Bartholin
    INSERM U453, Centre Leon Berard, 69373 Lyon, France
    Oncogene 21:2227-35. 2002

Collaborators

  • Isabelle Treilleux
  • Vincent Cavailles
  • Olivier Tredan
  • Jack Michel Renoir
  • Veronique Maguer-Satta
  • Laurent Bartholin
  • Muriel Le Romancer
  • Coralie Poulard
  • Stephanie Sentis
  • Katia Bouchekioua-Bouzaghou
  • Yannis Robin-Lespinasse
  • Thiziri Nait Achour
  • Marie Claude Rostan
  • Claire Bianchin
  • Anne Pierre Morel
  • Stephan Jalaguier
  • Catherine Teyssier
  • Amandine Philippat
  • Juliette Rambaud
  • Nader Hussein
  • Annick Lucas
  • Sophie Goddard-Leon
  • Sylvie Chabaud
  • Emilie Lavergne
  • Pascale Cohen
  • Stéphanie Gobert-Gosse
  • Sophie Goddard
  • Nicolas Leconte
  • Chloé Kolytcheff
  • Murielle Le Romancer
  • Ruth Rimokh
  • Laurence Jonard

Detail Information

Publications11

  1. doi Regulation of estrogen rapid signaling through arginine methylation by PRMT1
    Muriel Le Romancer
    INSERM, U590, Lyon F 69008, France Université de Lyon, Lyon 1, ISPB and IFR62, Lyon F 69003, France
    Mol Cell 31:212-21. 2008
    ..Our data indicate that the methylation of ERalpha is a physiological process occurring in the cytoplasm of normal and malignant epithelial breast cells and that ERalpha is hypermethylated in a subset of breast cancers...
  2. doi Cracking the estrogen receptor's posttranslational code in breast tumors
    Muriel Le Romancer
    Universite de Lyon, Centre de Recherche en Cancérologie de Lyon, Centre Leon Berard, bâtiment Cheney D, 28 rue Laennec, 69373 Lyon Cedex 08, France
    Endocr Rev 32:597-622. 2011
    ....
  3. ncbi hCAF1, a new regulator of PRMT1-dependent arginine methylation
    Yannis Robin-Lespinasse
    Inserm Unit U590, Centre Leon Berard, 28 rue Laennec, 69373 Lyon Cedex 08, France and Université Claude Bernard Lyon 1, Lyon, France
    J Cell Sci 120:638-47. 2007
    ..Since hCAF1 and PRMT1 have been involved in the regulation of transcription and RNA metabolism, we speculate that hCAF1 and PRMT1 could contribute to the crosstalk between transcription and RNA processing...
  4. pmc Activation of rapid oestrogen signalling in aggressive human breast cancers
    Coralie Poulard
    Universite de Lyon, France
    EMBO Mol Med 4:1200-13. 2012
    ..Our data introduces the new concept that the rapid oestrogen pathway is operative in vivo. It also provides a rationale for patient stratification defined by the activation of this pathway and the identification of target therapies...
  5. doi [Post-translational modifications modulate estrogen receptor alpha activity in breast tumors]
    Coralie Poulard
    Equipe labélisée Ligue contre le cancer, INSERM U590, Centre Leon Berard, bâtiment Cheney D, Lyon F 69008, France
    Med Sci (Paris) 26:636-40. 2010
    ..A better understanding of the impact of these PTMs on estrogen receptor should help in the identification of new drugs for breast cancer treatments...
  6. ncbi Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity
    Stephanie Sentis
    Institut National de la Sante et de la Recherche Medicale, Unité 590, Centre Leon Berard, 28 rue Laennec, 69373 Lyon Cedex 08, France
    Mol Endocrinol 19:2671-84. 2005
    ..These findings identify sumoylation as a new mechanism modulating ERalpha-dependent cellular response and provide a link between the SUMO and estrogen pathways...
  7. ncbi BTG2 antiproliferative protein interacts with the human CCR4 complex existing in vivo in three cell-cycle-regulated forms
    Anne Pierre Morel
    Unité INSERM U590, Centre Leon Berard, 69373 Lyon Cedex 08, France
    J Cell Sci 116:2929-36. 2003
    ..These findings suggest that the different regulatory pathways in which hCAF1 is involved, notably transcription regulation and mRNA turnover, may occur through distinct CCR4 complexes in the course of cell-cycle progression...
  8. ncbi Identification of NF-kappaB responsive elements in follistatin related gene (FLRG) promoter
    Laurent Bartholin
    INSERM, U590, IFR62, Lyon, F 69008, France
    Gene 393:153-62. 2007
    ..In all, this work brings new insights in the understanding of FLRG regulation by cytokines and growth factors. It opens attractive perspectives of research that should allow us to better understand the role of FLRG during tumorigenesis...
  9. pmc JMJD6 regulates ERα methylation on arginine
    Coralie Poulard
    Universite de Lyon, F 69000 Lyon, France Université Lyon 1, F 69000 Lyon, France INSERM U1052, Centre de Recherche en Cancérologie de Lyon, F 69000 Lyon, France CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, F 69000 Lyon, France Equipe Labellisée La Ligue
    PLoS ONE 9:e87982. 2014
    ..We propose that the demethylase activity of JMJD6 is a decisive regulator of the rapid physiological responses to oestrogen. ..
  10. ncbi Transcription activation of FLRG and follistatin by activin A, through Smad proteins, participates in a negative feedback loop to modulate activin A function
    Laurent Bartholin
    INSERM U453, Centre Leon Berard, 69373 Lyon, France
    Oncogene 21:2227-35. 2002
    ..This observation, in conjunction with the antagonistic effect of FLRG and follistatin on activin signaling, indicates that these two proteins participate in a negative feedback loop which regulates the activin function...
  11. pmc Transcriptional repression of estrogen receptor α signaling by SENP2 in breast cancer cells
    Thiziri Nait Achour
    Institut de Recherche en Cancérologie de Montpellier, Institut de Recherche en Cancérologie de Montpellier, INSERM, Unité 896, Universite Montpellier 1, and Institut régional du Cancer Montpellier, Montpellier T N A, C T, A L, V C, S J, F 34298, France Université Lyon 1 S S, A P, L C, F 69000 Lyon, France INSERM Unité 1052, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5286, Centre de Recherche en Cancérologie de Lyon, Equipe labellisée, La Ligue, F 69008 Lyon, France and Institut des Sciences Pharmaceutiques et Biologiques S S, Faculté de Pharmacie de Lyon, Universite Lyon 1, F 69000 Lyon, France
    Mol Endocrinol 28:183-96. 2014
    ..Altogether, our study unravels a new property for a SUMO protease and identifies SENP2 as a classical transcription coregulator. ..