Laura Corbo

Summary

Affiliation: Institut Paoli-Calmettes
Country: France

Publications

  1. doi Regulation of estrogen rapid signaling through arginine methylation by PRMT1
    Muriel Le Romancer
    INSERM, U590, Lyon F 69008, France Université de Lyon, Lyon 1, ISPB and IFR62, Lyon F 69003, France
    Mol Cell 31:212-21. 2008
  2. doi Cracking the estrogen receptor's posttranslational code in breast tumors
    Muriel Le Romancer
    Universite de Lyon, Centre de Recherche en Cancérologie de Lyon, Centre Leon Berard, bâtiment Cheney D, 28 rue Laennec, 69373 Lyon Cedex 08, France
    Endocr Rev 32:597-622. 2011
  3. ncbi hCAF1, a new regulator of PRMT1-dependent arginine methylation
    Yannis Robin-Lespinasse
    Inserm Unit U590, Centre Leon Berard, 28 rue Laennec, 69373 Lyon Cedex 08, France and Université Claude Bernard Lyon 1, Lyon, France
    J Cell Sci 120:638-47. 2007
  4. pmc Activation of rapid oestrogen signalling in aggressive human breast cancers
    Coralie Poulard
    Universite de Lyon, France
    EMBO Mol Med 4:1200-13. 2012
  5. doi [Post-translational modifications modulate estrogen receptor alpha activity in breast tumors]
    Coralie Poulard
    Equipe labélisée Ligue contre le cancer, INSERM U590, Centre Leon Berard, bâtiment Cheney D, Lyon F 69008, France
    Med Sci (Paris) 26:636-40. 2010
  6. ncbi Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity
    Stephanie Sentis
    Institut National de la Sante et de la Recherche Medicale, Unité 590, Centre Leon Berard, 28 rue Laennec, 69373 Lyon Cedex 08, France
    Mol Endocrinol 19:2671-84. 2005
  7. ncbi BTG2 antiproliferative protein interacts with the human CCR4 complex existing in vivo in three cell-cycle-regulated forms
    Anne Pierre Morel
    Unité INSERM U590, Centre Leon Berard, 69373 Lyon Cedex 08, France
    J Cell Sci 116:2929-36. 2003
  8. ncbi Identification of NF-kappaB responsive elements in follistatin related gene (FLRG) promoter
    Laurent Bartholin
    INSERM, U590, IFR62, Lyon, F 69008, France
    Gene 393:153-62. 2007
  9. ncbi Transcription activation of FLRG and follistatin by activin A, through Smad proteins, participates in a negative feedback loop to modulate activin A function
    Laurent Bartholin
    INSERM U453, Centre Leon Berard, 69373 Lyon, France
    Oncogene 21:2227-35. 2002

Collaborators

Detail Information

Publications9

  1. doi Regulation of estrogen rapid signaling through arginine methylation by PRMT1
    Muriel Le Romancer
    INSERM, U590, Lyon F 69008, France Université de Lyon, Lyon 1, ISPB and IFR62, Lyon F 69003, France
    Mol Cell 31:212-21. 2008
    ..Our data indicate that the methylation of ERalpha is a physiological process occurring in the cytoplasm of normal and malignant epithelial breast cells and that ERalpha is hypermethylated in a subset of breast cancers...
  2. doi Cracking the estrogen receptor's posttranslational code in breast tumors
    Muriel Le Romancer
    Universite de Lyon, Centre de Recherche en Cancérologie de Lyon, Centre Leon Berard, bâtiment Cheney D, 28 rue Laennec, 69373 Lyon Cedex 08, France
    Endocr Rev 32:597-622. 2011
    ....
  3. ncbi hCAF1, a new regulator of PRMT1-dependent arginine methylation
    Yannis Robin-Lespinasse
    Inserm Unit U590, Centre Leon Berard, 28 rue Laennec, 69373 Lyon Cedex 08, France and Université Claude Bernard Lyon 1, Lyon, France
    J Cell Sci 120:638-47. 2007
    ..Since hCAF1 and PRMT1 have been involved in the regulation of transcription and RNA metabolism, we speculate that hCAF1 and PRMT1 could contribute to the crosstalk between transcription and RNA processing...
  4. pmc Activation of rapid oestrogen signalling in aggressive human breast cancers
    Coralie Poulard
    Universite de Lyon, France
    EMBO Mol Med 4:1200-13. 2012
    ..Our data introduces the new concept that the rapid oestrogen pathway is operative in vivo. It also provides a rationale for patient stratification defined by the activation of this pathway and the identification of target therapies...
  5. doi [Post-translational modifications modulate estrogen receptor alpha activity in breast tumors]
    Coralie Poulard
    Equipe labélisée Ligue contre le cancer, INSERM U590, Centre Leon Berard, bâtiment Cheney D, Lyon F 69008, France
    Med Sci (Paris) 26:636-40. 2010
    ..A better understanding of the impact of these PTMs on estrogen receptor should help in the identification of new drugs for breast cancer treatments...
  6. ncbi Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity
    Stephanie Sentis
    Institut National de la Sante et de la Recherche Medicale, Unité 590, Centre Leon Berard, 28 rue Laennec, 69373 Lyon Cedex 08, France
    Mol Endocrinol 19:2671-84. 2005
    ..These findings identify sumoylation as a new mechanism modulating ERalpha-dependent cellular response and provide a link between the SUMO and estrogen pathways...
  7. ncbi BTG2 antiproliferative protein interacts with the human CCR4 complex existing in vivo in three cell-cycle-regulated forms
    Anne Pierre Morel
    Unité INSERM U590, Centre Leon Berard, 69373 Lyon Cedex 08, France
    J Cell Sci 116:2929-36. 2003
    ..These findings suggest that the different regulatory pathways in which hCAF1 is involved, notably transcription regulation and mRNA turnover, may occur through distinct CCR4 complexes in the course of cell-cycle progression...
  8. ncbi Identification of NF-kappaB responsive elements in follistatin related gene (FLRG) promoter
    Laurent Bartholin
    INSERM, U590, IFR62, Lyon, F 69008, France
    Gene 393:153-62. 2007
    ..In all, this work brings new insights in the understanding of FLRG regulation by cytokines and growth factors. It opens attractive perspectives of research that should allow us to better understand the role of FLRG during tumorigenesis...
  9. ncbi Transcription activation of FLRG and follistatin by activin A, through Smad proteins, participates in a negative feedback loop to modulate activin A function
    Laurent Bartholin
    INSERM U453, Centre Leon Berard, 69373 Lyon, France
    Oncogene 21:2227-35. 2002
    ..This observation, in conjunction with the antagonistic effect of FLRG and follistatin on activin signaling, indicates that these two proteins participate in a negative feedback loop which regulates the activin function...