Frederic Chibon

Summary

Affiliation: Institut Bergoni
Country: France

Publications

  1. doi request reprint Prediction of HER2 gene status in Her2 2+ invasive breast cancer: a study of 108 cases comparing ASCO/CAP and FDA recommendations
    Frederic Chibon
    Department of Pathology, Institut Bergonie, Bordeaux, France
    Mod Pathol 22:403-9. 2009
  2. doi request reprint Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity
    Frederic Chibon
    Departement de Pathologie, Institut Bergonie, Bordeaux, France
    Nat Med 16:781-7. 2010
  3. doi request reprint Impact of molecular analysis on the final sarcoma diagnosis: a study on 763 cases collected during a European epidemiological study
    Agnes Neuville
    Department of Pathology, Bergonie Cancer Institute, University of Bordeaux, 229 Cours de l Argonne, Bordeaux Cedex, France
    Am J Surg Pathol 37:1259-68. 2013
  4. doi request reprint YWHAE rearrangement identified by FISH and RT-PCR in endometrial stromal sarcomas: genetic and pathological correlations
    Sabrina Croce
    Department of Pathology, Institut Bergonie, Bordeaux, France
    Mod Pathol 26:1390-400. 2013
  5. doi request reprint Genetic profiling identifies two classes of soft-tissue leiomyosarcomas with distinct clinical characteristics
    Antoine Italiano
    Department of Medical Oncology, INSERM U916, Institut Bergonie, Bordeaux, France
    Clin Cancer Res 19:1190-6. 2013
  6. pmc MED12 alterations in both human benign and malignant uterine soft tissue tumors
    Gaëlle Pérot
    INSERM U916, Institut Bergonié Cancer Institute, Bordeaux, France
    PLoS ONE 7:e40015. 2012
  7. doi request reprint Fibrosarcoma-like lipomatous neoplasm: a reappraisal of so-called spindle cell liposarcoma defining a unique lipomatous tumor unrelated to other liposarcomas
    Andrea T Deyrup
    Department of Pathology, University of South Carolina School of Medicine Greenville, Greenville, SC Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA Department of Pathology and INSERM U916 Institut Bergonié Laboratory of Pathology, Universite Victor Segalen Bordeaux 2, Bordeaux, France Department of Pathology, University Hospital, Lausanne, Switzerland
    Am J Surg Pathol 37:1373-8. 2013
  8. pmc Prognostic value of PLAGL1-specific CpG site methylation in soft-tissue sarcomas
    Anne Lise Peille
    Institut Bergonie, Comprehensive Cancer Centre, Bordeaux, France Univ Bordeaux, Bordeaux, France INSERM U916 VINCO, Bordeaux, France
    PLoS ONE 8:e80741. 2013
  9. doi request reprint Adult-type rhabdomyosarcoma: analysis of 57 cases with clinicopathologic description, identification of 3 morphologic patterns and prognosis
    Nathalie Stock
    Bergonié Institute and INSERM U 916, Bordeaux, France
    Am J Surg Pathol 33:1850-9. 2009
  10. doi request reprint Chromosome instability accounts for reverse metastatic outcomes of pediatric and adult synovial sarcomas
    Pauline Lagarde
    Institut Nationalde la Santé et de la Recherche Médicale INSERM U916 Institut Bergonie, France
    J Clin Oncol 31:608-15. 2013

Collaborators

Detail Information

Publications14

  1. doi request reprint Prediction of HER2 gene status in Her2 2+ invasive breast cancer: a study of 108 cases comparing ASCO/CAP and FDA recommendations
    Frederic Chibon
    Department of Pathology, Institut Bergonie, Bordeaux, France
    Mod Pathol 22:403-9. 2009
    ..Pathological factors, in particular SBR grade 3 and more than 60% Her2+ cells, were significantly correlated with HER2 amplification...
  2. doi request reprint Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity
    Frederic Chibon
    Departement de Pathologie, Institut Bergonie, Bordeaux, France
    Nat Med 16:781-7. 2010
    ..Application of the signature will permit more selective use of adjuvant therapies for people with sarcomas, leading to decreased iatrogenic morbidity and improved outcomes for such individuals...
  3. doi request reprint Impact of molecular analysis on the final sarcoma diagnosis: a study on 763 cases collected during a European epidemiological study
    Agnes Neuville
    Department of Pathology, Bergonie Cancer Institute, University of Bordeaux, 229 Cours de l Argonne, Bordeaux Cedex, France
    Am J Surg Pathol 37:1259-68. 2013
    ....
  4. doi request reprint YWHAE rearrangement identified by FISH and RT-PCR in endometrial stromal sarcomas: genetic and pathological correlations
    Sabrina Croce
    Department of Pathology, Institut Bergonie, Bordeaux, France
    Mod Pathol 26:1390-400. 2013
    ..Overall, for endometrial sarcoma cases with high-grade morphology we recommend to test for YWHAE rearrangements by FISH break-apart, a cost- and time-efficient method, and to complete the investigation by RT-PCR in borderline cases. ..
  5. doi request reprint Genetic profiling identifies two classes of soft-tissue leiomyosarcomas with distinct clinical characteristics
    Antoine Italiano
    Department of Medical Oncology, INSERM U916, Institut Bergonie, Bordeaux, France
    Clin Cancer Res 19:1190-6. 2013
    ..Data about the prognostic factors of soft-tissue leiomyosarcomas and their correlation with molecular profile are limited...
  6. pmc MED12 alterations in both human benign and malignant uterine soft tissue tumors
    Gaëlle Pérot
    INSERM U916, Institut Bergonié Cancer Institute, Bordeaux, France
    PLoS ONE 7:e40015. 2012
    ..We propose here that MED12 alterations could be implicated in the development of smooth muscle tumor and that its expression could be inhibited in malignant tumors...
  7. doi request reprint Fibrosarcoma-like lipomatous neoplasm: a reappraisal of so-called spindle cell liposarcoma defining a unique lipomatous tumor unrelated to other liposarcomas
    Andrea T Deyrup
    Department of Pathology, University of South Carolina School of Medicine Greenville, Greenville, SC Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA Department of Pathology and INSERM U916 Institut Bergonié Laboratory of Pathology, Universite Victor Segalen Bordeaux 2, Bordeaux, France Department of Pathology, University Hospital, Lausanne, Switzerland
    Am J Surg Pathol 37:1373-8. 2013
    ....
  8. pmc Prognostic value of PLAGL1-specific CpG site methylation in soft-tissue sarcomas
    Anne Lise Peille
    Institut Bergonie, Comprehensive Cancer Centre, Bordeaux, France Univ Bordeaux, Bordeaux, France INSERM U916 VINCO, Bordeaux, France
    PLoS ONE 8:e80741. 2013
    ..Such a biomarker may be relevant for identifying patients likely to derive greater benefit from treatment. ..
  9. doi request reprint Adult-type rhabdomyosarcoma: analysis of 57 cases with clinicopathologic description, identification of 3 morphologic patterns and prognosis
    Nathalie Stock
    Bergonié Institute and INSERM U 916, Bordeaux, France
    Am J Surg Pathol 33:1850-9. 2009
    ..In conclusion, adult-type RMS is a rare sarcoma occurring mainly in the extremities and trunk wall with 2 main histologic patterns, spindle cell, and pleomorphic patterns, which represent the end of the spectrum of a single entity...
  10. doi request reprint Chromosome instability accounts for reverse metastatic outcomes of pediatric and adult synovial sarcomas
    Pauline Lagarde
    Institut Nationalde la Santé et de la Recherche Médicale INSERM U916 Institut Bergonie, France
    J Clin Oncol 31:608-15. 2013
    ..Here we investigate whether these signatures can also predict outcomes in SS...
  11. doi request reprint Grading of soft tissue sarcomas: from histological to molecular assessment
    Agnes Neuville
    1Department of Biopathology, Institut Bergonié and INSERM U916 2Laboratory of Pathology, University Victor Ségalen Bordeaux 3Translational Research, Institut Bergonie, Bordeaux, France
    Pathology 46:113-20. 2014
    ....
  12. doi request reprint Cancer gene expression signatures - the rise and fall?
    Frederic Chibon
    INSERM U916 Genetic and Biology of Sarcomas, Department of Molecular Pathology, Institut Bergonie, 229 Cours de l Argonne, CS61283, 33076 Bordeaux Cedex, France
    Eur J Cancer 49:2000-9. 2013
    ....
  13. doi request reprint Value and limitation of immunohistochemical expression of HMGA2 in mesenchymal tumors: about a series of 1052 cases
    Nadège Dreux
    Department of Pathology, Institut Bergonie, 229 Cours de l Argonne, Bordeaux Cedex, France
    Mod Pathol 23:1657-66. 2010
    ..Finally, and may be more importantly, HMGA2 is useful for the diagnosis of benign fibrous histiocytoma, nodular fasciitis and vulvovaginal benign mesenchymal tumors...
  14. doi request reprint Molecular characterization by array comparative genomic hybridization and DNA sequencing of 194 desmoid tumors
    Sébastien Salas
    Department of Pathology, INSERM U916, Bergonie Institute, 229 Cours de l Argonne, Bordeaux Cedex, France
    Genes Chromosomes Cancer 49:560-8. 2010
    ..A better understanding of the pathogenetic pathways in the initiation and progression of desmoid tumors requires studies of 8q and 20q gains, as well as of 6q and 5q losses, and study of the Wnt/beta-catenin pathway...