Sandrine Caputo

Summary

Affiliation: Institut Curie - Hopital Ren
Location: Saint Cloud, France

Publications

  1. ncbi NMR assignment of region 655-775 of human MAN1
    Sandrine Caputo
    , CEA Saclay, 91191, Gif-sur-Yvette, France
    J Biomol NMR 36:2. 2006
  2. ncbi The carboxyl-terminal nucleoplasmic region of MAN1 exhibits a DNA binding winged helix domain
    Sandrine Caputo
    Département d Ingénierie et d Etudes des Protéines Direction des Sciences du Vivant, Bâtiment 152, Commissariat à l Energie Atomique Saclay, 91191 Gif sur Yvette Cedex, France
    J Biol Chem 281:18208-15. 2006
  3. ncbi S1 ribosomal protein functions in translation initiation and ribonuclease RegB activation are mediated by similar RNA-protein interactions: an NMR and SAXS analysis
    Pascale Aliprandi
    CNRS, Antenne de l ICSN à l Ecole Polytechnique, Ecole Polytechnique, 91128 Palaiseau, France
    J Biol Chem 283:13289-301. 2008
  4. ncbi The R439C mutation in LMNA causes lamin oligomerization and susceptibility to oxidative stress
    Valerie L R M Verstraeten
    Department of Dermatology, University Hospital Maastricht, The Netherlands
    J Cell Mol Med 13:959-71. 2009
  5. ncbi Structural analysis of the Smad2-MAN1 interaction that regulates transforming growth factor-β signaling at the inner nuclear membrane
    Emilie Kondé
    Laboratoire de Biologie Structurale et Radiobiologie, URA CNRS 2096, CEA Saclay, 91190 Gif sur Yvette, France
    Biochemistry 49:8020-32. 2010
  6. ncbi An entire exon 3 germ-line rearrangement in the BRCA2 gene: pathogenic relevance of exon 3 deletion in breast cancer predisposition
    Daniele Muller
    Division of oncogenetic, Department of Biology and Pathology, Regional Cancer Centre Paul Strauss, BP30042, 67065 Strasbourg, France
    BMC Med Genet 12:121. 2011
  7. ncbi ENIGMA--evidence-based network for the interpretation of germline mutant alleles: an international initiative to evaluate risk and clinical significance associated with sequence variation in BRCA1 and BRCA2 genes
    Amanda B Spurdle
    Queensland Institute of Medical Research, Brisbane, Australia
    Hum Mutat 33:2-7. 2012
  8. ncbi Description and analysis of genetic variants in French hereditary breast and ovarian cancer families recorded in the UMD-BRCA1/BRCA2 databases
    Sandrine Caputo
    Institut Curie Hôpital René Huguenin, Service d Oncogénétique, U735 INSERM Saint Cloud, France
    Nucleic Acids Res 40:D992-1002. 2012

Collaborators

Detail Information

Publications9

  1. ncbi NMR assignment of region 655-775 of human MAN1
    Sandrine Caputo
    , CEA Saclay, 91191, Gif-sur-Yvette, France
    J Biomol NMR 36:2. 2006
  2. ncbi The carboxyl-terminal nucleoplasmic region of MAN1 exhibits a DNA binding winged helix domain
    Sandrine Caputo
    Département d Ingénierie et d Etudes des Protéines Direction des Sciences du Vivant, Bâtiment 152, Commissariat à l Energie Atomique Saclay, 91191 Gif sur Yvette Cedex, France
    J Biol Chem 281:18208-15. 2006
    ..This suggests that MAN1 binds simultaneously to R-Smads and their targeted DNA sequences...
  3. ncbi S1 ribosomal protein functions in translation initiation and ribonuclease RegB activation are mediated by similar RNA-protein interactions: an NMR and SAXS analysis
    Pascale Aliprandi
    CNRS, Antenne de l ICSN à l Ecole Polytechnique, Ecole Polytechnique, 91128 Palaiseau, France
    J Biol Chem 283:13289-301. 2008
    ..All of these results suggest that the ability of S1 to recognize different RNAs results from a high adaptability of both its structure and its binding surface...
  4. ncbi The R439C mutation in LMNA causes lamin oligomerization and susceptibility to oxidative stress
    Valerie L R M Verstraeten
    Department of Dermatology, University Hospital Maastricht, The Netherlands
    J Cell Mol Med 13:959-71. 2009
    ....
  5. ncbi Structural analysis of the Smad2-MAN1 interaction that regulates transforming growth factor-β signaling at the inner nuclear membrane
    Emilie Kondé
    Laboratoire de Biologie Structurale et Radiobiologie, URA CNRS 2096, CEA Saclay, 91190 Gif sur Yvette, France
    Biochemistry 49:8020-32. 2010
    ..On the basis of the structural heterogeneity and binding properties of the linker, we suggest that it can interact with other UHM domains, thus regulating the MAN1-Smad2 interaction...
  6. ncbi An entire exon 3 germ-line rearrangement in the BRCA2 gene: pathogenic relevance of exon 3 deletion in breast cancer predisposition
    Daniele Muller
    Division of oncogenetic, Department of Biology and Pathology, Regional Cancer Centre Paul Strauss, BP30042, 67065 Strasbourg, France
    BMC Med Genet 12:121. 2011
    ..Low levels of alternative transcripts lacking exon 3 (Δ3 delta3 transcript) have been reported in normal tissues, which raises the question whether deletion of exon 3 is pathogenic...
  7. ncbi ENIGMA--evidence-based network for the interpretation of germline mutant alleles: an international initiative to evaluate risk and clinical significance associated with sequence variation in BRCA1 and BRCA2 genes
    Amanda B Spurdle
    Queensland Institute of Medical Research, Brisbane, Australia
    Hum Mutat 33:2-7. 2012
    ..It is envisaged that the research and clinical application of models developed by ENIGMA will be relevant to the interpretation of sequence variants in other disease genes...
  8. ncbi Description and analysis of genetic variants in French hereditary breast and ovarian cancer families recorded in the UMD-BRCA1/BRCA2 databases
    Sandrine Caputo
    Institut Curie Hôpital René Huguenin, Service d Oncogénétique, U735 INSERM Saint Cloud, France
    Nucleic Acids Res 40:D992-1002. 2012
    ..In this article, we report some novel UVs not contained in the BIC database and explore their impact in cancer predisposition based on a structural approach...