Carmen Buchrieser

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. ncbi request reprint Comparison of the genome sequences of Listeria monocytogenes and Listeria innocua: clues for evolution and pathogenicity
    Carmen Buchrieser
    Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 25, rue du Dr Roux, 75724 Paris Cedex 15, France
    FEMS Immunol Med Microbiol 35:207-13. 2003
  2. pmc Comparative genomics and transcriptomics of lineages I, II, and III strains of Listeria monocytogenes
    Torsten Hain
    Institute of Medical Microbiology, Justus Liebig University, Schubertstrasse 81, Giessen, D 35392, Germany
    BMC Genomics 13:144. 2012
  3. pmc The 102-kilobase pgm locus of Yersinia pestis: sequence analysis and comparison of selected regions among different Yersinia pestis and Yersinia pseudotuberculosis strains
    C Buchrieser
    Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 75724 Paris Cedex 15, France
    Infect Immun 67:4851-61. 1999
  4. ncbi request reprint Legionella pneumophila - a human pathogen that co-evolved with fresh water protozoa
    C Albert-Weissenberger
    Unité de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Institut Pasteur, 25 rue du Dr Roux, 75724, Paris Cedex 15, France
    Cell Mol Life Sci 64:432-48. 2007
  5. ncbi request reprint Biodiversity of the species Listeria monocytogenes and the genus Listeria
    Carmen Buchrieser
    Unité de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris, France
    Microbes Infect 9:1147-55. 2007
  6. pmc Complete genome sequence of the animal pathogen Listeria ivanovii, which provides insights into host specificities and evolution of the genus Listeria
    C Buchrieser
    Institut Pasteur, Biologie des Bactéries Intracellulaires and CNRS URA 2171, 75724 Paris, France
    J Bacteriol 193:6787-8. 2011
  7. pmc Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease
    Christel Cazalet
    Institut Pasteur, Biologie des Bactéries Intracellulaires, CNRS URA 2171, Paris, France
    PLoS Genet 6:e1000851. 2010
  8. ncbi request reprint Genetic diversity of Listeria monocytogenes recovered from infected persons and pork, seafood and dairy products on retail sale in France during 2000 and 2001
    Eva Hong
    Laboratoire des Listeria, Centre National de Référence des Listeria, World Health Organisation Collaborating Center for Foodborne Listeriosis, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Int J Food Microbiol 114:187-94. 2007
  9. ncbi request reprint Genomic diversity and evolution within the species Streptococcus agalactiae
    Mathieu Brochet
    Unité de Génomique des Microorganismes Pathogènes URA CNRS 2171, Institut Pasteur, 25 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France
    Microbes Infect 8:1227-43. 2006
  10. pmc Comparative transcriptome analysis of Listeria monocytogenes strains of the two major lineages reveals differences in virulence, cell wall, and stress response
    Patricia Severino
    Unité de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Appl Environ Microbiol 73:6078-88. 2007

Detail Information

Publications64

  1. ncbi request reprint Comparison of the genome sequences of Listeria monocytogenes and Listeria innocua: clues for evolution and pathogenicity
    Carmen Buchrieser
    Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 25, rue du Dr Roux, 75724 Paris Cedex 15, France
    FEMS Immunol Med Microbiol 35:207-13. 2003
    ....
  2. pmc Comparative genomics and transcriptomics of lineages I, II, and III strains of Listeria monocytogenes
    Torsten Hain
    Institute of Medical Microbiology, Justus Liebig University, Schubertstrasse 81, Giessen, D 35392, Germany
    BMC Genomics 13:144. 2012
    ..monocytogenes. Lineage III, represented by the 4a L99 genome is known to contain strains less virulent for humans...
  3. pmc The 102-kilobase pgm locus of Yersinia pestis: sequence analysis and comparison of selected regions among different Yersinia pestis and Yersinia pseudotuberculosis strains
    C Buchrieser
    Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 75724 Paris Cedex 15, France
    Infect Immun 67:4851-61. 1999
    ..Furthermore, sequence comparisons among 29 Yersinia strains suggest that Y. pestis is a recently emerged pathogen that is probably entering the initial phase of reductive evolution...
  4. ncbi request reprint Legionella pneumophila - a human pathogen that co-evolved with fresh water protozoa
    C Albert-Weissenberger
    Unité de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Institut Pasteur, 25 rue du Dr Roux, 75724, Paris Cedex 15, France
    Cell Mol Life Sci 64:432-48. 2007
    ..This review summarizes what is currently known about regulation of the Legionella life cycle and gives insight in the Legionella-specific features as deduced from genome analysis...
  5. ncbi request reprint Biodiversity of the species Listeria monocytogenes and the genus Listeria
    Carmen Buchrieser
    Unité de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris, France
    Microbes Infect 9:1147-55. 2007
    ..Then large-scale studies comparing gene content of Listeria and how these studies contributed to typing applications will be discussed. Finally, evolutionary conclusions and future perspectives in Listeria genomics are presented...
  6. pmc Complete genome sequence of the animal pathogen Listeria ivanovii, which provides insights into host specificities and evolution of the genus Listeria
    C Buchrieser
    Institut Pasteur, Biologie des Bactéries Intracellulaires and CNRS URA 2171, 75724 Paris, France
    J Bacteriol 193:6787-8. 2011
    ..The sequence and its analysis are available at an interactive genome browser at the Institut Pasteur (http://genolist.pasteur.fr/LivaList/)...
  7. pmc Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease
    Christel Cazalet
    Institut Pasteur, Biologie des Bactéries Intracellulaires, CNRS URA 2171, Paris, France
    PLoS Genet 6:e1000851. 2010
    ..longbeachae is encapsulated. These species-specific differences may account for the different environmental niches and disease epidemiology of these two Legionella species...
  8. ncbi request reprint Genetic diversity of Listeria monocytogenes recovered from infected persons and pork, seafood and dairy products on retail sale in France during 2000 and 2001
    Eva Hong
    Laboratoire des Listeria, Centre National de Référence des Listeria, World Health Organisation Collaborating Center for Foodborne Listeriosis, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Int J Food Microbiol 114:187-94. 2007
    ..The ability of strains to multiply in different niches may be determined by the presence or absence of these genes...
  9. ncbi request reprint Genomic diversity and evolution within the species Streptococcus agalactiae
    Mathieu Brochet
    Unité de Génomique des Microorganismes Pathogènes URA CNRS 2171, Institut Pasteur, 25 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France
    Microbes Infect 8:1227-43. 2006
    ..The study highlights for the first time that this lineage contains a specific and conserved set of surface proteins, probably accounting for its high capacity to cause infections in newborns...
  10. pmc Comparative transcriptome analysis of Listeria monocytogenes strains of the two major lineages reveals differences in virulence, cell wall, and stress response
    Patricia Severino
    Unité de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Appl Environ Microbiol 73:6078-88. 2007
    ..These findings suggest different patterns of interaction with host cells and the environment, key factors for host colonization and survival in the environment...
  11. ncbi request reprint Specific regions of genome plasticity and genetic diversity of the commensal Escherichia coli A0 34/86
    Jana Hejnova
    Unité de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28 rue du Dr Roux, F 75724 Paris, France
    Int J Med Microbiol 296:541-6. 2006
    ..coli strain 536 were all identified in E. coli A0 34/86. This comparative analysis underlines the important genome heterogeneity between E. coli strains...
  12. pmc Two small ncRNAs jointly govern virulence and transmission in Legionella pneumophila
    Tobias Sahr
    Institut Pasteur, Biologie des Bactéries Intracellulaires and CNRS URA 2171, 28 rue du Dr Roux, Paris, France
    Mol Microbiol 72:741-62. 2009
    ..We suggest that rather RpoS and LetA, by influencing LetE and probably cyclic-di-GMP levels, regulate motility in L. pneumophila...
  13. doi request reprint Deep sequencing defines the transcriptional map of L. pneumophila and identifies growth phase-dependent regulated ncRNAs implicated in virulence
    Tobias Sahr
    Institut Pasteur, 28, rue du Dr Roux, Paris 75724, France
    RNA Biol 9:503-19. 2012
    ..pneumophila genome, identified many new ncRNAs and will provide a framework for the understanding of virulence and adaptation properties of L. pneumophila...
  14. ncbi request reprint Virulence strategies for infecting phagocytes deduced from the in vivo transcriptional program of Legionella pneumophila
    Holger Bruggemann
    Unité de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Paris, France
    Cell Microbiol 8:1228-40. 2006
    ..Analysis of a fliA (sigma28) deletion mutant identified genes coregulated with the flagellar regulon, including GGDEF/EAL regulators and factors that promote host cell entry and survival...
  15. pmc NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitidis
    Christophe Rusniok
    Génomique des Microorganismes Pathogènes, Institut Pasteur, rue du Dr Roux, Paris 75015, France
    Genome Biol 10:R110. 2009
    ..This holds true for Neisseria meningitidis, one of the most feared human bacterial pathogens that causes meningitis and septicemia...
  16. pmc Multigenome analysis identifies a worldwide distributed epidemic Legionella pneumophila clone that emerged within a highly diverse species
    Christel Cazalet
    Unité de Génomique des Microorganismes Pathogènes, Institut Pasteur, 75724 Paris Cedex 15, France
    Genome Res 18:431-41. 2008
    ..However, the genomic background also plays a role in disease causation as demonstrated by the identification of a globally distributed epidemic strain exhibiting the genotype of the sequenced L. pneumophila strain Paris...
  17. ncbi request reprint Legionella pneumophila adaptation to intracellular life and the host response: clues from genomics and transcriptomics
    Matthieu Jules
    Unité de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Institut Pasteur, 25 28 Rue du Dr Roux, 75724 Paris Cedex 15, France
    FEBS Lett 581:2829-38. 2007
    ..pneumophila, the transcriptional host response of the model host Dictyostelium discoideum and will present hypotheses drawn from these data with respect to subversion of host cell functions and virulence of L. pneumophila...
  18. ncbi request reprint Use of DNA arrays for the analysis of outbreak-related strains of Listeria monocytogenes
    Michel Doumith
    Laboratoire des Listeria, Centre National de Référence des Listeria, World Health Organisation Collaborating Center for Foodborne Listeriosis, Institut Pasteur, 25 28 Rue du Dr Roux, F 75724 Paris Cedex 15, France
    Int J Med Microbiol 296:559-62. 2006
    ..We show that this approach allows clarifying the genetic basis of the pattern variations. In the reported outbreak, the differences were due to phage excision, showing the power of this technique in epidemiological studies...
  19. pmc Differentiation of the major Listeria monocytogenes serovars by multiplex PCR
    Michel Doumith
    Laboratoire des Listeria Centre National de Référence des Listeria World Health Organization Collaborating Center for Foodborne Listeriosis, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris Cedex 15, France
    J Clin Microbiol 42:3819-22. 2004
    ..The PCR test, which constitutes a rapid and practical alternative to laborious classical serotyping, was successfully evaluated with 222 Listeria strains...
  20. ncbi request reprint Characterization of the flexible genome complement of the commensal Escherichia coli strain A0 34/86 (O83 : K24 : H31)
    Jana Hejnova
    Unité de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris, France
    Microbiology 151:385-98. 2005
    ..These results highlight the thin line between bacterial 'virulence' and 'fitness' or 'colonization' factors, and question the definition of enterobacterial virulence factors...
  21. ncbi request reprint Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity
    Christel Cazalet
    Laboratoire de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Institut Pasteur, 28, rue du Dr Roux, 75724 Paris Cedex 15, France
    Nat Genet 36:1165-73. 2004
    ..The genome thus reflects the history and lifestyle of L. pneumophila, a human pathogen of macrophages that coevolved with fresh-water amoebae...
  22. ncbi request reprint Transcriptome analysis of Listeria monocytogenes identifies three groups of genes differently regulated by PrfA
    Eliane Milohanic
    Unité des Interactions Bactéries Cellules and Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28, rue du Docteur Roux, 75724 Paris Cedex 15, France
    Mol Microbiol 47:1613-25. 2003
    ..This study reveals that PrfA can act as an activator or a repressor and suggests that PrfA may directly or indirectly activate different sets of genes in association with different sigma factors...
  23. pmc New aspects regarding evolution and virulence of Listeria monocytogenes revealed by comparative genomics and DNA arrays
    Michel Doumith
    Laboratoire des Listeria, Centre National de Référence des Listeria, World Health Organization Collaborating Center for Foodborne Listeriosis, Institut Pasteur, 75724 Paris 15, France
    Infect Immun 72:1072-83. 2004
    ..monocytogenes strains...
  24. pmc Control of flagellar gene regulation in Legionella pneumophila and its relation to growth phase
    Christiane Albert-Weissenberger
    Institut Pasteur, Biologie des Bactéries Intracellulaires, 75724 Paris Cedex 15, France
    J Bacteriol 192:446-55. 2010
    ..Finally, FliA induces expression of flagellar class III and IV genes leading to the complete synthesis of the flagellum...
  25. pmc Extensive recombination events and horizontal gene transfer shaped the Legionella pneumophila genomes
    Laura Gomez-Valero
    Institut Pasteur, Biologie des Bactéries Intracellulaires, 75724, Paris, France
    BMC Genomics 12:536. 2011
    ....
  26. pmc DNA macroarray for identification and typing of Staphylococcus aureus isolates
    Salim Trad
    Département Ecosystèmes et Epidémiologie des Maladies Infectieuses, Institut Pasteur, Paris, France
    J Clin Microbiol 42:2054-64. 2004
    ..In conclusion, the macroarray designed for this study offers an attractive and rapid typing method which has the advantage of providing additional information concerning the gene content of the isolate of interest...
  27. ncbi request reprint Adaptation of Legionella pneumophila to the host environment: role of protein secretion, effectors and eukaryotic-like proteins
    Holger Bruggemann
    Unité de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris, France
    Curr Opin Microbiol 9:86-94. 2006
    ..pneumophila are the many secretion systems delivering these and other effectors to the host cell. Recent studies have highlighted the multi-functional role of these factors secreted by L. pneumophila, in host-pathogen interactions...
  28. doi request reprint Genome sequence of Vibrio splendidus: an abundant planctonic marine species with a large genotypic diversity
    Frédérique Le Roux
    Institut Pasteur, Unité Plasticité du Génome Bactérien, CNRS URA 2171, F 75015, Paris, France
    Environ Microbiol 11:1959-70. 2009
    ..Those results suggest that marine Vibrio can be a source of antibiotic resistance genes...
  29. doi request reprint Molecular mimicry: an important virulence strategy employed by Legionella pneumophila to subvert host functions
    Tamara Nora
    Institut Pasteur, Biologie des Bactéries Intracellulaires and CNRS URA 2171, 75724 Paris, France
    Future Microbiol 4:691-701. 2009
    ..Collectively, these data have shed new light on the virulence strategies of L. pneumophila, a major aspect of which is molecular mimicry...
  30. ncbi request reprint The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens
    Eric Duchaud
    Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Nat Biotechnol 21:1307-13. 2003
    ..Moreover, newly identified insecticidal proteins may be effective alternatives for the control of insect pests...
  31. ncbi request reprint Listeria monocytogenes bile salt hydrolase is a PrfA-regulated virulence factor involved in the intestinal and hepatic phases of listeriosis
    Olivier Dussurget
    Unité des Interactions Bactéries Cellules, Institut Pasteur, Paris, France
    Mol Microbiol 45:1095-106. 2002
    ..Taken together, these results demonstrate that BSH is a novel PrfA-regulated L. monocytogenes virulence factor involved in the intestinal and hepatic phases of listeriosis...
  32. doi request reprint cDNA library construction for next-generation sequencing to determine the transcriptional landscape of Legionella pneumophila
    Tobias Sahr
    Biologie des Bactéries Intracellulaires, Institut Pasteur, Paris, France
    Methods Mol Biol 954:555-66. 2013
    ..In this chapter we describe the construction of cDNA libraries for (1) RNA deep sequencing (RNA-seq) and (2) TSS mapping using the Illumina technology...
  33. doi request reprint Legionella pneumophila effector RomA uniquely modifies host chromatin to repress gene expression and promote intracellular bacterial replication
    Monica Rolando
    Institut Pasteur, Unité Biologie des Bactéries Intracellulaires, Paris 75015, France
    Cell Host Microbe 13:395-405. 2013
    ..Thus, a secreted L. pneumophila effector targets the host cell nucleus and modifies histones to repress gene expression and promote efficient intracellular replication...
  34. doi request reprint Co-immunoprecipitation: protein-RNA and protein-DNA interaction
    Tobias Sahr
    Biologie des Bactéries Intracellulaires, Institut Pasteur, Paris, France
    Methods Mol Biol 954:583-93. 2013
    ....
  35. ncbi request reprint Macro-array and bioinformatic analyses reveal mycobacterial 'core' genes, variation in the ESAT-6 gene family and new phylogenetic markers for the Mycobacterium tuberculosis complex
    Magali Marmiesse
    Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 25 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France
    Microbiology 150:483-96. 2004
    ..tuberculosis complex recently presented...
  36. doi request reprint Listeria rocourtiae sp. nov
    Alexandre Leclercq
    Groupe Microorganismes et Barrières de l Hôte, French National Reference Center for Listeria, Paris, France
    Int J Syst Evol Microbiol 60:2210-4. 2010
    ..nov. is proposed for the novel species. The type strain is CIP 109804(T) (=DSM 22097(T) =Allerberger 700284/02(T)). The type strain is avirulent as assessed by cell culture assays and inoculation of mice...
  37. ncbi request reprint CAAT-Box, Contigs-Assembly and Annotation Tool-Box for genome sequencing projects
    L Frangeul
    Genopole, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris 15, France
    Bioinformatics 20:790-7. 2004
    ..Using this strategy, the user works with a group of IPFs independently of the closure phase progression. The IPFs are accessible by a web server and can therefore be modified and commented by different groups...
  38. ncbi request reprint Monoclonality or oligoclonality of human herpesvirus 8 terminal repeat sequences in Kaposi's sarcoma and other diseases
    J G Judde
    Unité d Oncologie Virale, Departement des Retrovirus, Institut Pasteur, Paris, France
    J Natl Cancer Inst 92:729-36. 2000
    ..The purpose of this study was to examine whether the number of terminal repeats (TRs) contained in the fused TR region of HHV8 could be used as a marker of clonality in HHV8-associated tumors...
  39. pmc Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions
    Laura Gomez-Valero
    Institut Pasteur, Unité de Biologie des Bactéries Intracellulaires Paris, France
    Front Microbiol 2:208. 2011
    ..Finally, evolutionary aspects regarding the eukaryotic like proteins in Legionella are discussed...
  40. ncbi request reprint Comparative genomics of Listeria species
    P Glaser
    , , Service d'Informatique Scientifique, Institut Pasteur, 25-28 rue du Dr. Roux, 75724 Paris, France
    Science 294:849-52. 2001
    ..The presence of 270 L. monocytogenes and 149 L. innocua strain-specific genes (clustered in 100 and 63 islets, respectively) suggests that virulence in Listeria results from multiple gene acquisition and deletion events...
  41. doi request reprint Induction of competence for natural transformation in Legionella pneumophila and exploitation for mutant construction
    Carmen Buchrieser
    Biology of Intracellular Bacteria, Institut Pasteur, Paris, France
    Methods Mol Biol 954:183-95. 2013
    ..This approach seems to be less prone to the appearance of secondary mutations during mutant construction as compared to procedures using electroporation...
  42. doi request reprint Post-translational modifications of host proteins by Legionella pneumophila: a sophisticated survival strategy
    Monica Rolando
    Institut Pasteur, Biologie des Bactéries Intracellulaires, 75724 Paris, France
    Future Microbiol 7:369-81. 2012
    ..In this review, we focus on those effectors in the repertoire of L. pneumophila proteins that target key cellular pathways by specific post-translational modifications...
  43. ncbi request reprint The high-pathogenicity island of Yersinia pseudotuberculosis can be inserted into any of the three chromosomal asn tRNA genes
    C Buchrieser
    Unité de bactériologie moléculaire et médicale, Laboratoire des Yersinia, Institut Pasteur, Paris, France
    Mol Microbiol 30:965-78. 1998
    ....
  44. doi request reprint Population variation in NAIP functional copy number confers increased cell death upon Legionella pneumophila infection
    Michele Boniotto
    Unit of Human Evolutionary Genetics, Institut Pasteur, F 75015 Paris, France
    Hum Immunol 73:196-200. 2012
    ..We postulate that the NAIPFull gene duplication might have been evolutionary maintained, or even selected for, because it may confer an advantage to the host against flagellated bacteria...
  45. pmc Circadian clock proteins in prokaryotes: hidden rhythms?
    Maria Loza-Correa
    Institut Pasteur, Unité de Biologie des Bactéries Intracellulaires Paris, France
    Front Microbiol 1:130. 2010
    ..All of the residues described for the biochemical functions of the main pacemaker KaiC in Synechococcus elongatus are also conserved in the L. pneumophila KaiC protein...
  46. pmc Transferable plasmid-mediated resistance to streptomycin in a clinical isolate of Yersinia pestis
    A Guiyoule
    Laboratoire des Yersinia, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris, France
    Emerg Infect Dis 7:43-8. 2001
    ..Emergence of resistance to streptomycin in Y. pestis represents a critical public health problem since this antibiotic is used as the first-line treatment against plague in many countries...
  47. pmc A new evolutionary scenario for the Mycobacterium tuberculosis complex
    R Brosch
    Unite de Genetique Moleculaire Bacterienne, Laboratoire de Génomique des Microorganismes Pathogènes, and Centre National de Référence des Mycobactéries, Institut Pasteur, 25 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France
    Proc Natl Acad Sci U S A 99:3684-9. 2002
    ..bovis lineage separated from the M. tuberculosis lineage. This observation suggests that the common ancestor of the tubercle bacilli resembled M. tuberculosis or M. canettii and could well have been a human pathogen already...
  48. doi request reprint Legionella pneumophila: population genetics, phylogeny and genomics
    L Gomez-Valero
    Institut Pasteur, Unité de Biologie des Bactéries Intracellulaires and CNRS URA 2171, 25 28 Rue du Dr Roux, 75724 Paris, France
    Infect Genet Evol 9:727-39. 2009
    ..pneumophila populations, the techniques used to study the molecular epidemiology and evolution of L. pneumophila, the knowledge gained from genome analysis, and discusses future perspectives...
  49. pmc Analysis of genome plasticity in pathogenic and commensal Escherichia coli isolates by use of DNA arrays
    Ulrich Dobrindt
    Institut für Molekulare Infektionsbiologie der Universität Würzburg, 97070 Wurzburg, Germany
    J Bacteriol 185:1831-40. 2003
    ..coli strains and underline the fact that both the acquisition and deletion of DNA elements are important processes involved in the evolution of prokaryotes...
  50. pmc Significant role for ladC in initiation of Legionella pneumophila infection
    Hayley J Newton
    Australian Bacterial Pathogenesis Program, Department of Microbiology, Monash University, Victoria 3800, Australia
    Infect Immun 76:3075-85. 2008
    ..castellanii infection. Although the mechanism by which LadC modulates the initial interaction between the bacterium and host cell remains unclear, we have established that LadC plays an important role in L. pneumophila infection...
  51. ncbi request reprint Global analysis of gene expression in an rpoN mutant of Listeria monocytogenes
    Safia Arous
    Equipe de Microbiologie Fondamentale et Appliquée, Universite de Poitiers, 40 Avenue du Recteur Pineau, 86022 Poitiers Cedex, France
    Microbiology 150:1581-90. 2004
    ..These results suggest that sigma(54) is mainly involved in the control of carbohydrate metabolism in L. monocytogenes via direct regulation of PTS activity, alteration of the pyruvate pool and modulation of carbon catabolite regulation...
  52. pmc The pathogenicity island-associated K15 capsule determinant exhibits a novel genetic structure and correlates with virulence in uropathogenic Escherichia coli strain 536
    György Schneider
    Institut für Molekulare Infektionsbiologie, Universitat Wurzburg, Wurzburg, Germany
    Infect Immun 72:5993-6001. 2004
    ..Expression of the K15 capsule is important for virulence in a murine model of ascending urinary tract infection but not for serum resistance of E. coli strain 536...
  53. pmc How to become a uropathogen: comparative genomic analysis of extraintestinal pathogenic Escherichia coli strains
    Elzbieta Brzuszkiewicz
    Göttingen Genomics Laboratory, Institute of Microbiology and Genetics, Georg August Universitat Gottingen, Grisebachstrasse 8, 37077 Gottingen, Germany
    Proc Natl Acad Sci U S A 103:12879-84. 2006
    ..Accordingly, instead of a common virulence mechanism, different ways exist among ExPEC to cause disease...
  54. doi request reprint Transcriptional profiling of Legionella pneumophila biofilm cells and the influence of iron on biofilm formation
    Thomas Hindré
    Laboratoire de Chimie de l Eau et de l Environnement, UMR 6008, Universite de Poitiers, 40 Avenue du Recteur Pineau, 86022 Poitiers Cedex, France
    Microbiology 154:30-41. 2008
    ..However, biofilm formation by L. pneumophila wild-type and a DeltapvcA strain was clearly inhibited in iron-rich conditions...
  55. pmc The presence of the internalin gene in natural atypically hemolytic Listeria innocua strains suggests descent from L. monocytogenes
    Dmitriy V Volokhov
    FDA, 5100 Paint Branch Pkwy, College Park, MD 20740, USA
    Appl Environ Microbiol 73:1928-39. 2007
    ..innocua strains altered by horizontal transfer. It is more likely that they are distinct relics of the evolution of L. innocua from an ancestral L. monocytogenes, as postulated by others...
  56. ncbi request reprint The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA
    André Tiaden
    Institute of Microbiology, ETH Zurich, Wolfgang Pauli Strasse 10, 8093 Zurich, Switzerland
    Cell Microbiol 9:2903-20. 2007
    ..Our findings indicate that LqsR is a novel pleiotropic regulator involved in RpoS- and LetA-controlled interactions of L. pneumophila with phagocytes...
  57. pmc The Legionella autoinducer synthase LqsA produces an alpha-hydroxyketone signaling molecule
    Thomas Spirig
    Institute of Microbiology, ETH Zurich, Zurich, Switzerland
    J Biol Chem 283:18113-23. 2008
    ..Thus, LqsA and CqsA belong to a family of pyridoxal 5'-phosphate-dependent autoinducer synthases, which produce the alpha-hydroxyketone signaling molecules LAI-1 and CAI-1...
  58. ncbi request reprint Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease
    Philippe Glaser
    Laboratoire de Génomique des Microorganismes Pathogènes, Institute Pasteur, Paris, France
    Mol Microbiol 45:1499-513. 2002
    ..Compared with other pathogenic streptococci, S. agalactiae shows the unique feature that pathogenicity islands may have an important role in virulence acquisition and in genetic diversity...
  59. ncbi request reprint Legionella pathogenicity: genome structure, regulatory networks and the host cell response
    Michael Steinert
    Institut fur Mikrobiologie, Technische Universitat Braunschweig, Spielmannstr 7, D 38106 Braunschweig, Germany
    Int J Med Microbiol 297:577-87. 2007
    ..The use of this model organism made it possible to develop a roadmap of host cell factors which significantly contribute to the uptake of L. pneumophila and the establishment of an ER-associated replicative vacuole...
  60. ncbi request reprint Pathogenomics of Listeria spp
    Torsten Hain
    Institute for Medical Microbiology, Justus Liebig University, Frankfurter Strasse 107, D 35392 Giessen, Germany
    Int J Med Microbiol 297:541-57. 2007
    ..to understand genome evolution and diversity, as well as physiological aspects of metabolism utilized by the bacteria when growing in diverse and varied environments...
  61. ncbi request reprint Growth-phase-dependent mobility of the lvh-encoding region in Legionella pneumophila strain Paris
    Anne Doléans-Jordheim
    INSERM, E0230, Lyon, F 69008, France
    Microbiology 152:3561-8. 2006
    ..A similar plasmid-like element was described in the Lens strain genome, suggesting that the mobility of the lvh region is a phenomenon widespread among Legionella sp...
  62. ncbi request reprint [What do we learn from the genome of Legionella pneumophila?]
    Christel Cazalet
    Med Sci (Paris) 21:455-7. 2005
  63. ncbi request reprint How seryl-phosphorylated HPr inhibits PrfA, a transcription activator of Listeria monocytogenes virulence genes
    Rana Herro
    Microbiologie et Genetique Moleculaire, CNRS INRA INA PG, Thiverval Grignon, France
    J Mol Microbiol Biotechnol 9:224-34. 2005
    ..In agreement with this concept, disruption of the enzyme I- or HPr-encoding genes also strongly inhibited PrfA activity. PrfA activity therefore seems to depend on a fully functional PTS phosphorylation cascade...
  64. ncbi request reprint Pathogenomics of mobile genetic elements of toxigenic bacteria
    Jörg Hacker
    University of Wurzburg, Institute for Molecular Biology of Infectious Diseases, Wurzburg, Germany
    Int J Med Microbiol 293:453-61. 2004
    ..In this review, we focus on the role of mobile genetic elements that may also contain toxin-encoding genes for genome variability and evolution of bacteria...