Carmen Buchrieser

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. pmc Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions
    Laura Gomez-Valero
    Institut Pasteur, Unité de Biologie des Bactéries Intracellulaires Paris, France
    Front Microbiol 2:208. 2011
  2. pmc Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease
    Christel Cazalet
    Institut Pasteur, Biologie des Bactéries Intracellulaires, CNRS URA 2171, Paris, France
    PLoS Genet 6:e1000851. 2010
  3. pmc Circadian clock proteins in prokaryotes: hidden rhythms?
    Maria Loza-Correa
    Institut Pasteur, Unité de Biologie des Bactéries Intracellulaires Paris, France
    Front Microbiol 1:130. 2010
  4. ncbi request reprint Genomic diversity and evolution within the species Streptococcus agalactiae
    Mathieu Brochet
    Unité de Génomique des Microorganismes Pathogènes URA CNRS 2171, Institut Pasteur, 25 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France
    Microbes Infect 8:1227-43. 2006
  5. ncbi request reprint Genetic diversity of Listeria monocytogenes recovered from infected persons and pork, seafood and dairy products on retail sale in France during 2000 and 2001
    Eva Hong
    Laboratoire des Listeria, Centre National de Référence des Listeria, World Health Organisation Collaborating Center for Foodborne Listeriosis, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Int J Food Microbiol 114:187-94. 2007
  6. ncbi request reprint Virulence strategies for infecting phagocytes deduced from the in vivo transcriptional program of Legionella pneumophila
    Holger Bruggemann
    Unité de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Paris, France
    Cell Microbiol 8:1228-40. 2006
  7. pmc Comparative transcriptome analysis of Listeria monocytogenes strains of the two major lineages reveals differences in virulence, cell wall, and stress response
    Patricia Severino
    Unité de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Appl Environ Microbiol 73:6078-88. 2007
  8. doi request reprint Deep sequencing defines the transcriptional map of L. pneumophila and identifies growth phase-dependent regulated ncRNAs implicated in virulence
    Tobias Sahr
    Institut Pasteur, 28, rue du Dr Roux, Paris 75724, France
    RNA Biol 9:503-19. 2012
  9. ncbi request reprint Specific regions of genome plasticity and genetic diversity of the commensal Escherichia coli A0 34/86
    Jana Hejnova
    Unité de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28 rue du Dr Roux, F 75724 Paris, France
    Int J Med Microbiol 296:541-6. 2006
  10. pmc Two small ncRNAs jointly govern virulence and transmission in Legionella pneumophila
    Tobias Sahr
    Institut Pasteur, Biologie des Bactéries Intracellulaires and CNRS URA 2171, 28 rue du Dr Roux, Paris, France
    Mol Microbiol 72:741-62. 2009

Collaborators

Detail Information

Publications41

  1. pmc Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions
    Laura Gomez-Valero
    Institut Pasteur, Unité de Biologie des Bactéries Intracellulaires Paris, France
    Front Microbiol 2:208. 2011
    ..Finally, evolutionary aspects regarding the eukaryotic like proteins in Legionella are discussed...
  2. pmc Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease
    Christel Cazalet
    Institut Pasteur, Biologie des Bactéries Intracellulaires, CNRS URA 2171, Paris, France
    PLoS Genet 6:e1000851. 2010
    ..longbeachae is encapsulated. These species-specific differences may account for the different environmental niches and disease epidemiology of these two Legionella species...
  3. pmc Circadian clock proteins in prokaryotes: hidden rhythms?
    Maria Loza-Correa
    Institut Pasteur, Unité de Biologie des Bactéries Intracellulaires Paris, France
    Front Microbiol 1:130. 2010
    ..All of the residues described for the biochemical functions of the main pacemaker KaiC in Synechococcus elongatus are also conserved in the L. pneumophila KaiC protein...
  4. ncbi request reprint Genomic diversity and evolution within the species Streptococcus agalactiae
    Mathieu Brochet
    Unité de Génomique des Microorganismes Pathogènes URA CNRS 2171, Institut Pasteur, 25 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France
    Microbes Infect 8:1227-43. 2006
    ..The study highlights for the first time that this lineage contains a specific and conserved set of surface proteins, probably accounting for its high capacity to cause infections in newborns...
  5. ncbi request reprint Genetic diversity of Listeria monocytogenes recovered from infected persons and pork, seafood and dairy products on retail sale in France during 2000 and 2001
    Eva Hong
    Laboratoire des Listeria, Centre National de Référence des Listeria, World Health Organisation Collaborating Center for Foodborne Listeriosis, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Int J Food Microbiol 114:187-94. 2007
    ..The ability of strains to multiply in different niches may be determined by the presence or absence of these genes...
  6. ncbi request reprint Virulence strategies for infecting phagocytes deduced from the in vivo transcriptional program of Legionella pneumophila
    Holger Bruggemann
    Unité de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Paris, France
    Cell Microbiol 8:1228-40. 2006
    ..Analysis of a fliA (sigma28) deletion mutant identified genes coregulated with the flagellar regulon, including GGDEF/EAL regulators and factors that promote host cell entry and survival...
  7. pmc Comparative transcriptome analysis of Listeria monocytogenes strains of the two major lineages reveals differences in virulence, cell wall, and stress response
    Patricia Severino
    Unité de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Appl Environ Microbiol 73:6078-88. 2007
    ..These findings suggest different patterns of interaction with host cells and the environment, key factors for host colonization and survival in the environment...
  8. doi request reprint Deep sequencing defines the transcriptional map of L. pneumophila and identifies growth phase-dependent regulated ncRNAs implicated in virulence
    Tobias Sahr
    Institut Pasteur, 28, rue du Dr Roux, Paris 75724, France
    RNA Biol 9:503-19. 2012
    ..pneumophila genome, identified many new ncRNAs and will provide a framework for the understanding of virulence and adaptation properties of L. pneumophila...
  9. ncbi request reprint Specific regions of genome plasticity and genetic diversity of the commensal Escherichia coli A0 34/86
    Jana Hejnova
    Unité de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28 rue du Dr Roux, F 75724 Paris, France
    Int J Med Microbiol 296:541-6. 2006
    ..coli strain 536 were all identified in E. coli A0 34/86. This comparative analysis underlines the important genome heterogeneity between E. coli strains...
  10. pmc Two small ncRNAs jointly govern virulence and transmission in Legionella pneumophila
    Tobias Sahr
    Institut Pasteur, Biologie des Bactéries Intracellulaires and CNRS URA 2171, 28 rue du Dr Roux, Paris, France
    Mol Microbiol 72:741-62. 2009
    ..We suggest that rather RpoS and LetA, by influencing LetE and probably cyclic-di-GMP levels, regulate motility in L. pneumophila...
  11. ncbi request reprint Transcriptome analysis of Listeria monocytogenes identifies three groups of genes differently regulated by PrfA
    Eliane Milohanic
    Unité des Interactions Bactéries Cellules and Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28, rue du Docteur Roux, 75724 Paris Cedex 15, France
    Mol Microbiol 47:1613-25. 2003
    ..This study reveals that PrfA can act as an activator or a repressor and suggests that PrfA may directly or indirectly activate different sets of genes in association with different sigma factors...
  12. pmc NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitidis
    Christophe Rusniok
    Génomique des Microorganismes Pathogènes, Institut Pasteur, rue du Dr Roux, Paris 75015, France
    Genome Biol 10:R110. 2009
    ..This holds true for Neisseria meningitidis, one of the most feared human bacterial pathogens that causes meningitis and septicemia...
  13. pmc Multigenome analysis identifies a worldwide distributed epidemic Legionella pneumophila clone that emerged within a highly diverse species
    Christel Cazalet
    Unité de Génomique des Microorganismes Pathogènes, Institut Pasteur, 75724 Paris Cedex 15, France
    Genome Res 18:431-41. 2008
    ..However, the genomic background also plays a role in disease causation as demonstrated by the identification of a globally distributed epidemic strain exhibiting the genotype of the sequenced L. pneumophila strain Paris...
  14. ncbi request reprint The Legionella pneumophila kai operon is implicated in stress response and confers fitness in competitive environments
    Maria Loza-Correa
    Institut Pasteur, Biologie des Bactéries Intracellulaires, Paris, France CNRS UMR 3525, Paris, France
    Environ Microbiol 16:359-81. 2014
    ..pneumophila KaiBC resemble Synechosystis KaiC2B2 and not circadian KaiB1C1. Thus, the L. pneumophila Kai proteins do not encode a circadian clock, but enhance stress resistance and adaption to changes in the environments. ..
  15. ncbi request reprint Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity
    Christel Cazalet
    Laboratoire de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Institut Pasteur, 28, rue du Dr Roux, 75724 Paris Cedex 15, France
    Nat Genet 36:1165-73. 2004
    ..The genome thus reflects the history and lifestyle of L. pneumophila, a human pathogen of macrophages that coevolved with fresh-water amoebae...
  16. pmc Differentiation of the major Listeria monocytogenes serovars by multiplex PCR
    Michel Doumith
    Laboratoire des Listeria Centre National de Référence des Listeria World Health Organization Collaborating Center for Foodborne Listeriosis, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris Cedex 15, France
    J Clin Microbiol 42:3819-22. 2004
    ..The PCR test, which constitutes a rapid and practical alternative to laborious classical serotyping, was successfully evaluated with 222 Listeria strains...
  17. ncbi request reprint Use of DNA arrays for the analysis of outbreak-related strains of Listeria monocytogenes
    Michel Doumith
    Laboratoire des Listeria, Centre National de Référence des Listeria, World Health Organisation Collaborating Center for Foodborne Listeriosis, Institut Pasteur, 25 28 Rue du Dr Roux, F 75724 Paris Cedex 15, France
    Int J Med Microbiol 296:559-62. 2006
    ..We show that this approach allows clarifying the genetic basis of the pattern variations. In the reported outbreak, the differences were due to phage excision, showing the power of this technique in epidemiological studies...
  18. pmc Control of flagellar gene regulation in Legionella pneumophila and its relation to growth phase
    Christiane Albert-Weissenberger
    Institut Pasteur, Biologie des Bactéries Intracellulaires, 75724 Paris Cedex 15, France
    J Bacteriol 192:446-55. 2010
    ..Finally, FliA induces expression of flagellar class III and IV genes leading to the complete synthesis of the flagellum...
  19. ncbi request reprint Characterization of the flexible genome complement of the commensal Escherichia coli strain A0 34/86 (O83 : K24 : H31)
    Jana Hejnova
    Unité de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris, France
    Microbiology 151:385-98. 2005
    ..These results highlight the thin line between bacterial 'virulence' and 'fitness' or 'colonization' factors, and question the definition of enterobacterial virulence factors...
  20. ncbi request reprint Legionella pneumophila adaptation to intracellular life and the host response: clues from genomics and transcriptomics
    Matthieu Jules
    Unité de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Institut Pasteur, 25 28 Rue du Dr Roux, 75724 Paris Cedex 15, France
    FEBS Lett 581:2829-38. 2007
    ..pneumophila, the transcriptional host response of the model host Dictyostelium discoideum and will present hypotheses drawn from these data with respect to subversion of host cell functions and virulence of L. pneumophila...
  21. doi request reprint Molecular mimicry: an important virulence strategy employed by Legionella pneumophila to subvert host functions
    Tamara Nora
    Institut Pasteur, Biologie des Bactéries Intracellulaires and CNRS URA 2171, 75724 Paris, France
    Future Microbiol 4:691-701. 2009
    ..Collectively, these data have shed new light on the virulence strategies of L. pneumophila, a major aspect of which is molecular mimicry...
  22. pmc DNA macroarray for identification and typing of Staphylococcus aureus isolates
    Salim Trad
    Département Ecosystèmes et Epidémiologie des Maladies Infectieuses, Institut Pasteur, Paris, France
    J Clin Microbiol 42:2054-64. 2004
    ..In conclusion, the macroarray designed for this study offers an attractive and rapid typing method which has the advantage of providing additional information concerning the gene content of the isolate of interest...
  23. ncbi request reprint Comparison of the genome sequences of Listeria monocytogenes and Listeria innocua: clues for evolution and pathogenicity
    Carmen Buchrieser
    Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 25, rue du Dr Roux, 75724 Paris Cedex 15, France
    FEMS Immunol Med Microbiol 35:207-13. 2003
    ....
  24. pmc New aspects regarding evolution and virulence of Listeria monocytogenes revealed by comparative genomics and DNA arrays
    Michel Doumith
    Laboratoire des Listeria, Centre National de Référence des Listeria, World Health Organization Collaborating Center for Foodborne Listeriosis, Institut Pasteur, 75724 Paris 15, France
    Infect Immun 72:1072-83. 2004
    ..monocytogenes strains...
  25. ncbi request reprint Adaptation of Legionella pneumophila to the host environment: role of protein secretion, effectors and eukaryotic-like proteins
    Holger Bruggemann
    Unité de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris, France
    Curr Opin Microbiol 9:86-94. 2006
    ..pneumophila are the many secretion systems delivering these and other effectors to the host cell. Recent studies have highlighted the multi-functional role of these factors secreted by L. pneumophila, in host-pathogen interactions...
  26. doi request reprint Legionella pneumophila effector RomA uniquely modifies host chromatin to repress gene expression and promote intracellular bacterial replication
    Monica Rolando
    Institut Pasteur, Unité Biologie des Bactéries Intracellulaires, Paris 75015, France
    Cell Host Microbe 13:395-405. 2013
    ..Thus, a secreted L. pneumophila effector targets the host cell nucleus and modifies histones to repress gene expression and promote efficient intracellular replication...
  27. pmc Extensive recombination events and horizontal gene transfer shaped the Legionella pneumophila genomes
    Laura Gomez-Valero
    Institut Pasteur, Biologie des Bactéries Intracellulaires, 75724, Paris, France
    BMC Genomics 12:536. 2011
    ....
  28. doi request reprint Genome sequence of Vibrio splendidus: an abundant planctonic marine species with a large genotypic diversity
    Frédérique Le Roux
    Institut Pasteur, Unité Plasticité du Génome Bactérien, CNRS URA 2171, F 75015, Paris, France
    Environ Microbiol 11:1959-70. 2009
    ..Those results suggest that marine Vibrio can be a source of antibiotic resistance genes...
  29. ncbi request reprint Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease
    Philippe Glaser
    Laboratoire de Génomique des Microorganismes Pathogènes, Institute Pasteur, Paris, France
    Mol Microbiol 45:1499-513. 2002
    ..Compared with other pathogenic streptococci, S. agalactiae shows the unique feature that pathogenicity islands may have an important role in virulence acquisition and in genetic diversity...
  30. ncbi request reprint The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens
    Eric Duchaud
    Laboratoire de Génomique des Microorganismes Pathogènes, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Nat Biotechnol 21:1307-13. 2003
    ..Moreover, newly identified insecticidal proteins may be effective alternatives for the control of insect pests...
  31. ncbi request reprint From amoeba to macrophages: exploring the molecular mechanisms of Legionella pneumophila infection in both hosts
    Pedro Escoll
    Institut Pasteur, Biologie des Bactéries Intracellulaires and CNRS UMR, 3525, Paris, France
    Curr Top Microbiol Immunol 376:1-34. 2013
    ..This knowledge will be discussed in the light of recent findings from the Acanthamoeba castellanii genome analyses suggesting the existence of a primitive immune-like system in amoeba. ..
  32. doi request reprint Co-immunoprecipitation: protein-RNA and protein-DNA interaction
    Tobias Sahr
    Biologie des Bactéries Intracellulaires, Institut Pasteur, Paris, France
    Methods Mol Biol 954:583-93. 2013
    ....
  33. ncbi request reprint Biodiversity of the species Listeria monocytogenes and the genus Listeria
    Carmen Buchrieser
    Unité de Génomique des Microorganismes Pathogènes and CNRS URA 2171, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris, France
    Microbes Infect 9:1147-55. 2007
    ..Then large-scale studies comparing gene content of Listeria and how these studies contributed to typing applications will be discussed. Finally, evolutionary conclusions and future perspectives in Listeria genomics are presented...
  34. doi request reprint Characterization of an acetyltransferase that detoxifies aromatic chemicals in Legionella pneumophila
    Xavier Kubiak
    Universite Paris Diderot, Sorbonne Paris Cité, unité de Biologie Fonctionnelle et Adaptative, CNRS EAC4413, 75013, Paris, France
    Biochem J 445:219-28. 2012
    ..pneumophila biotransforms and detoxifies toxic aromatic chemicals. These data also emphasize the role of XMEs in the environmental adaptation of certain prokaryotes...
  35. doi request reprint cDNA library construction for next-generation sequencing to determine the transcriptional landscape of Legionella pneumophila
    Tobias Sahr
    Biologie des Bactéries Intracellulaires, Institut Pasteur, Paris, France
    Methods Mol Biol 954:555-66. 2013
    ..In this chapter we describe the construction of cDNA libraries for (1) RNA deep sequencing (RNA-seq) and (2) TSS mapping using the Illumina technology...
  36. doi request reprint Listeria rocourtiae sp. nov
    Alexandre Leclercq
    Groupe Microorganismes et Barrières de l Hôte, French National Reference Center for Listeria, Paris, France
    Int J Syst Evol Microbiol 60:2210-4. 2010
    ..nov. is proposed for the novel species. The type strain is CIP 109804(T) (=DSM 22097(T) =Allerberger 700284/02(T)). The type strain is avirulent as assessed by cell culture assays and inoculation of mice...
  37. ncbi request reprint Macro-array and bioinformatic analyses reveal mycobacterial 'core' genes, variation in the ESAT-6 gene family and new phylogenetic markers for the Mycobacterium tuberculosis complex
    Magali Marmiesse
    Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 25 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France
    Microbiology 150:483-96. 2004
    ..tuberculosis complex recently presented...
  38. ncbi request reprint Listeria monocytogenes bile salt hydrolase is a PrfA-regulated virulence factor involved in the intestinal and hepatic phases of listeriosis
    Olivier Dussurget
    Unité des Interactions Bactéries Cellules, Institut Pasteur, Paris, France
    Mol Microbiol 45:1095-106. 2002
    ..Taken together, these results demonstrate that BSH is a novel PrfA-regulated L. monocytogenes virulence factor involved in the intestinal and hepatic phases of listeriosis...
  39. doi request reprint Induction of competence for natural transformation in Legionella pneumophila and exploitation for mutant construction
    Carmen Buchrieser
    Biology of Intracellular Bacteria, Institut Pasteur, Paris, France
    Methods Mol Biol 954:183-95. 2013
    ..This approach seems to be less prone to the appearance of secondary mutations during mutant construction as compared to procedures using electroporation...
  40. doi request reprint Post-translational modifications of host proteins by Legionella pneumophila: a sophisticated survival strategy
    Monica Rolando
    Institut Pasteur, Biologie des Bactéries Intracellulaires, 75724 Paris, France
    Future Microbiol 7:369-81. 2012
    ..In this review, we focus on those effectors in the repertoire of L. pneumophila proteins that target key cellular pathways by specific post-translational modifications...
  41. doi request reprint Population variation in NAIP functional copy number confers increased cell death upon Legionella pneumophila infection
    Michele Boniotto
    Unit of Human Evolutionary Genetics, Institut Pasteur, F 75015 Paris, France
    Hum Immunol 73:196-200. 2012
    ..We postulate that the NAIPFull gene duplication might have been evolutionary maintained, or even selected for, because it may confer an advantage to the host against flagellated bacteria...