Affiliation: Institut National de la Recherche Agronomique
Bruhat A, Averous J, Carraro V, Zhong C, Reimold A, Kilberg M, et al. Differences in the molecular mechanisms involved in the transcriptional activation of the CHOP and asparagine synthetase genes in response to amino acid deprivation or activation of the unfolded protein response. J Biol Chem. 2002;277:48107-14 pubmed
..Collectively, these results document that there are significant differences in the molecular mechanisms involved in the transcriptional activation of CHOP and AS by amino acid limitation. ..
Bruhat A, Cherasse Y, Maurin A, Breitwieser W, Parry L, Deval C, et al. ATF2 is required for amino acid-regulated transcription by orchestrating specific histone acetylation. Nucleic Acids Res. 2007;35:1312-21 pubmed
..Thus, ATF2 is involved in promoting the modification of the chromatin structure to enhance the transcription of a number of amino acid-regulated genes. ..