Romulus Breban

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. doi request reprint A general multi-strain model with environmental transmission: invasion conditions for the disease-free and endemic states
    Romulus Breban
    Odum School of Ecology, University of Georgia, Athens, GA 30602, USA
    J Theor Biol 264:729-36. 2010
  2. pmc BCG-mediated bladder cancer immunotherapy: identifying determinants of treatment response using a calibrated mathematical model
    Cyrill A Rentsch
    Department of Urology, University Hospital of Basel, University of Basel, Basel, Switzerland
    PLoS ONE 8:e56327. 2013
  3. doi request reprint Towards realistic estimates of HCV incidence in Egypt
    R Breban
    Unité d Epidémiologie des Maladies Emergentes, Institut Pasteur, Paris, France
    J Viral Hepat 20:294-6. 2013
  4. doi request reprint Role of environmental persistence in pathogen transmission: a mathematical modeling approach
    Romulus Breban
    Unité d Epidémiologie des Maladies Emergentes, Institut Pasteur, 75724 Paris, France
    J Math Biol 66:535-46. 2013
  5. pmc Health newscasts for increasing influenza vaccination coverage: an inductive reasoning game approach
    Romulus Breban
    Unité d Epidémiologie des Maladies Emergentes, Institut Pasteur, Paris, France
    PLoS ONE 6:e28300. 2011
  6. pmc A universal long-term flu vaccine may not prevent severe epidemics
    Raffaele Vardavas
    RAND Corporation, Santa Monica, California, USA
    BMC Res Notes 3:92. 2010
  7. pmc Quantifying the treatment efficacy of reverse transcriptase inhibitors: new analyses of clinical data based on within-host modeling
    Romulus Breban
    Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    BMC Public Health 9:S11. 2009
  8. pmc The role of environmental transmission in recurrent avian influenza epidemics
    Romulus Breban
    Odum School of Ecology, University of Georgia, Athens, Georgia, United States of America
    PLoS Comput Biol 5:e1000346. 2009
  9. ncbi request reprint Mean-field analysis of an inductive reasoning game: application to influenza vaccination
    Romulus Breban
    Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California 90095 1555, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 76:031127. 2007
  10. pmc Can influenza epidemics be prevented by voluntary vaccination?
    Raffaele Vardavas
    Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, United States of America
    PLoS Comput Biol 3:e85. 2007

Detail Information

Publications15

  1. doi request reprint A general multi-strain model with environmental transmission: invasion conditions for the disease-free and endemic states
    Romulus Breban
    Odum School of Ecology, University of Georgia, Athens, GA 30602, USA
    J Theor Biol 264:729-36. 2010
    ..However, the endemic state of the first strain is neutrally stable to invasion by the second strain. Thus, our results suggest that environmental transmission makes the endemic state less resistant to invasion...
  2. pmc BCG-mediated bladder cancer immunotherapy: identifying determinants of treatment response using a calibrated mathematical model
    Cyrill A Rentsch
    Department of Urology, University Hospital of Basel, University of Basel, Basel, Switzerland
    PLoS ONE 8:e56327. 2013
    ..We provide insight into relevant clinical questions using a novel mathematical model of BCG immunotherapy. Our model predicts an altered regimen that may decrease side effects of treatment while improving response to therapy...
  3. doi request reprint Towards realistic estimates of HCV incidence in Egypt
    R Breban
    Unité d Epidémiologie des Maladies Emergentes, Institut Pasteur, Paris, France
    J Viral Hepat 20:294-6. 2013
    ..We propose an alternate approach to estimating incidence based on analysing cohort data; we find that the number of annual new infections is <150 000...
  4. doi request reprint Role of environmental persistence in pathogen transmission: a mathematical modeling approach
    Romulus Breban
    Unité d Epidémiologie des Maladies Emergentes, Institut Pasteur, 75724 Paris, France
    J Math Biol 66:535-46. 2013
    ..While environmental transmission is typically chosen over direct transmission in modeling cholera, this is not the case for influenza...
  5. pmc Health newscasts for increasing influenza vaccination coverage: an inductive reasoning game approach
    Romulus Breban
    Unité d Epidémiologie des Maladies Emergentes, Institut Pasteur, Paris, France
    PLoS ONE 6:e28300. 2011
    ..We show that broadcasting both the incidence and the vaccination coverage could yield either better or worse vaccination coverage than broadcasting each piece of information on its own...
  6. pmc A universal long-term flu vaccine may not prevent severe epidemics
    Raffaele Vardavas
    RAND Corporation, Santa Monica, California, USA
    BMC Res Notes 3:92. 2010
    ..However, due to complacency behavior, it remains unclear whether the introduction of such vaccines would maintain high and stable levels of vaccination coverage year after year...
  7. pmc Quantifying the treatment efficacy of reverse transcriptase inhibitors: new analyses of clinical data based on within-host modeling
    Romulus Breban
    Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    BMC Public Health 9:S11. 2009
    ..Current measures of the clinical efficacy of antiretroviral therapy (ART) in the treatment of HIV include the change in HIV RNA in the plasma and the gain in CD4 cells...
  8. pmc The role of environmental transmission in recurrent avian influenza epidemics
    Romulus Breban
    Odum School of Ecology, University of Georgia, Athens, Georgia, United States of America
    PLoS Comput Biol 5:e1000346. 2009
    ..Third, very low levels of environmental transmission (i.e., few cases per year) are sufficient for avian influenza to persist in populations where it would otherwise vanish...
  9. ncbi request reprint Mean-field analysis of an inductive reasoning game: application to influenza vaccination
    Romulus Breban
    Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California 90095 1555, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 76:031127. 2007
    ..Our analysis provides a practical method for identifying how many years of free vaccination should be provided in order to successfully ameliorate influenza epidemics...
  10. pmc Can influenza epidemics be prevented by voluntary vaccination?
    Raffaele Vardavas
    Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, United States of America
    PLoS Comput Biol 3:e85. 2007
    ..Finally, we discuss the implication of our results for controlling pandemics...
  11. ncbi request reprint Linking population-level models with growing networks: a class of epidemic models
    Romulus Breban
    Department of Biomathematics, University of California, Los Angeles, California 90095 1555, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 72:046110. 2005
    ..We discuss the computational advantages that our growing network model has over the CMJ branching process...
  12. ncbi request reprint Is there any evidence that syphilis epidemics cycle?
    Romulus Breban
    Department of Psychiatry, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    Lancet Infect Dis 8:577-81. 2008
    ..We explain the possible reasons for the previous proposal that syphilis epidemics cycle. Our findings imply that it is quite possible that the CDC could be successful in eliminating syphilis within the next few decades...
  13. ncbi request reprint Role of parametric resonance in virological failure during HIV treatment interruption therapy
    Romulus Breban
    Department of Biomathematics, Semel Institute for Neuroscience and Human Behavior and UCLA AIDS Institute, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    Lancet 367:1285-9. 2006
    ..Hence, our analyses show that no universal regimen with periodic interruptions will be effective for all patients...
  14. pmc Environmental transmission of low pathogenicity avian influenza viruses and its implications for pathogen invasion
    Pejman Rohani
    Odum School of Ecology, University of Georgia, Athens, GA 30602, USA
    Proc Natl Acad Sci U S A 106:10365-9. 2009
    ....
  15. doi request reprint Interhuman transmissibility of Middle East respiratory syndrome coronavirus: estimation of pandemic risk
    Romulus Breban
    Institut Pasteur, Emerging Diseases Epidemiology Unit, Paris, France
    Lancet 382:694-9. 2013
    ..We aimed to estimate virus transmissibility and the epidemic potential of MERS-CoV, and to compare the results with similar findings obtained for prepandemic SARS...