Sylvie Bonvalot

Summary

Affiliation: Institut Gustave Roussy
Country: France

Publications

  1. ncbi request reprint [Soft tissue sarcoma : improved quality of life with new surgical approaches]
    Sylvie Bonvalot
    Departement de Chirurgie Generale, Comité Sarcomes, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif, France
    Bull Cancer 89:1045-52. 2002
  2. doi request reprint Primary retroperitoneal sarcomas: a multivariate analysis of surgical factors associated with local control
    Sylvie Bonvalot
    Department of Surgery, Public Health, and Medical Oncology, Institut Gustave Roussy, Villejuif, France
    J Clin Oncol 27:31-7. 2009
  3. ncbi request reprint [Management of recurrent soft tissue sarcoma of the retroperitoneum]
    Sylvie Bonvalot
    Departement de Chirurgie, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif
    Bull Cancer 91:845-52. 2004
  4. ncbi request reprint [New surgical approaches to localized and advanced gastrointestinal stromal tumors (GIST)]
    Sylvie Bonvalot
    Institut Gustave Roussy, 39, rue Camille Desmoulins 94805 Villejuif
    Bull Acad Natl Med 196:855-60; discussion 860. 2012
  5. ncbi request reprint The treatment of desmoid tumors: a stepwise clinical approach
    S Bonvalot
    Department of Surgery, Institut Gustave Roussy, Villejuif, France
    Ann Oncol 23:x158-66. 2012
  6. doi request reprint Hyperthermic pelvic perfusion with tumor necrosis factor-α for locally advanced cancers: encouraging results of a phase II study
    Sylvie Bonvalot
    Department of Surgery, Institut Gustave Roussy, Villejuif Cedex, France
    Ann Surg 255:281-6. 2012
  7. ncbi request reprint Extra-abdominal primary fibromatosis: Aggressive management could be avoided in a subgroup of patients
    S Bonvalot
    Department of Surgery, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France
    Eur J Surg Oncol 34:462-8. 2008
  8. ncbi request reprint [Function preserving surgery of limb sarcomas: history and improvements]
    S Bonvalot
    Departement de Chirurgie, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Cancer Radiother 10:416-24. 2006
  9. ncbi request reprint [Diagnosis and treatment of gastrointestinal stromal tumours]
    Sylvie Bonvalot
    Departement de Chirurgie, Institut Gustave Roussy, 94805 Villejuif
    Rev Prat 56:359-67. 2006
  10. ncbi request reprint Limb salvage with isolated perfusion for soft tissue sarcoma: could less TNF-alpha be better?
    S Bonvalot
    Department of Surgery, Institut Gustave Roussy, Villejuif, France
    Ann Oncol 16:1061-8. 2005

Detail Information

Publications61

  1. ncbi request reprint [Soft tissue sarcoma : improved quality of life with new surgical approaches]
    Sylvie Bonvalot
    Departement de Chirurgie Generale, Comité Sarcomes, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif, France
    Bull Cancer 89:1045-52. 2002
    ..This is a review of diagnostic and therapeutic improvements which have allowed quality of life of patients with soft tissue sarcoma...
  2. doi request reprint Primary retroperitoneal sarcomas: a multivariate analysis of surgical factors associated with local control
    Sylvie Bonvalot
    Department of Surgery, Public Health, and Medical Oncology, Institut Gustave Roussy, Villejuif, France
    J Clin Oncol 27:31-7. 2009
    ..To define the optimal initial management and the best extent of surgery that would optimize margins on primary retroperitoneal sarcomas (RPS)...
  3. ncbi request reprint [Management of recurrent soft tissue sarcoma of the retroperitoneum]
    Sylvie Bonvalot
    Departement de Chirurgie, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif
    Bull Cancer 91:845-52. 2004
    ..Adequate management at the time of primary presentation is likely to afford the best chance for long-term survival...
  4. ncbi request reprint [New surgical approaches to localized and advanced gastrointestinal stromal tumors (GIST)]
    Sylvie Bonvalot
    Institut Gustave Roussy, 39, rue Camille Desmoulins 94805 Villejuif
    Bull Acad Natl Med 196:855-60; discussion 860. 2012
    ..The EORTC trial, designed to resolve this issue, was closed because of low accrual...
  5. ncbi request reprint The treatment of desmoid tumors: a stepwise clinical approach
    S Bonvalot
    Department of Surgery, Institut Gustave Roussy, Villejuif, France
    Ann Oncol 23:x158-66. 2012
    ....
  6. doi request reprint Hyperthermic pelvic perfusion with tumor necrosis factor-α for locally advanced cancers: encouraging results of a phase II study
    Sylvie Bonvalot
    Department of Surgery, Institut Gustave Roussy, Villejuif Cedex, France
    Ann Surg 255:281-6. 2012
    ..To assess the efficacy of isolated pelvic perfusion (IPP) with tumor necrosis factor (TNF)-α and melphalan in patients with locally advanced cancers in the pelvic and groin area requiring mutilating surgery...
  7. ncbi request reprint Extra-abdominal primary fibromatosis: Aggressive management could be avoided in a subgroup of patients
    S Bonvalot
    Department of Surgery, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France
    Eur J Surg Oncol 34:462-8. 2008
    ..To evaluate the impact of surgery as first-line treatment on event-free survival (EFS) of primary aggressive fibromatosis...
  8. ncbi request reprint [Function preserving surgery of limb sarcomas: history and improvements]
    S Bonvalot
    Departement de Chirurgie, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Cancer Radiother 10:416-24. 2006
    ..Efficacy and safety of low-dose TNFalpha could greatly facilitate ILP procedures in the near future...
  9. ncbi request reprint [Diagnosis and treatment of gastrointestinal stromal tumours]
    Sylvie Bonvalot
    Departement de Chirurgie, Institut Gustave Roussy, 94805 Villejuif
    Rev Prat 56:359-67. 2006
    ..New blockers of the tyrosine-kinase activity are currently in development in cases of resistance...
  10. ncbi request reprint Limb salvage with isolated perfusion for soft tissue sarcoma: could less TNF-alpha be better?
    S Bonvalot
    Department of Surgery, Institut Gustave Roussy, Villejuif, France
    Ann Oncol 16:1061-8. 2005
    ..The optimal dose of TNF-alpha delivered by isolated limb perfusion (ILP) in patients with locally advanced soft tissue sarcoma is still unknown...
  11. ncbi request reprint Randomized trial of cytoreduction followed by intraperitoneal chemotherapy versus cytoreduction alone in patients with peritoneal sarcomatosis
    S Bonvalot
    Department of Surgery, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif, France
    Eur J Surg Oncol 31:917-23. 2005
    ..In order to decrease loco-regional relapse after complete resection of peritoneal sarcomatosis (PS), the role of intraperitoneal chemotherapy (IPEC) was prospectively evaluated...
  12. doi request reprint [Pelvic perfusion for localy advanced tumors]
    Sylvie Bonvalot
    Departement de Chirurgie, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif
    Bull Cancer 96:103-9. 2009
    ..A randomized study will start soon...
  13. ncbi request reprint [Surgery of retroperitoneal sarcomas]
    S Bonvalot
    Departement de Chirurgie, Comité Sarcome, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Cancer Radiother 10:41-9. 2006
    ..The 5-year probability of local control is approximately 50%. The role of adjuvant therapy is evolving and at present should not be used outside the investigational setting...
  14. ncbi request reprint [An update of the surgical indications for gastrointestinal stromal tumors]
    S Bonvalot
    Departement de Chirurgie, Institut Gustave Roussy, Villejuif
    J Chir (Paris) 145:6S8-11. 2008
    ..A phase 3 EORTC study will start and will randomise this secondary surgery after 6 to 12 months of imatinib in responding patients...
  15. ncbi request reprint [Surgical management of GIST in the era of Gleevec]
    S Bonvalot
    Departement de Chirurgie, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif, France
    Ann Chir 130:144-51. 2005
    ..Surgery is being evaluated in the other responding patients. The majority of responses being limited to partial responses, best indications of surgery are when complete resection may be expected (< 10%)...
  16. ncbi request reprint Impact of surgery on advanced gastrointestinal stromal tumors (GIST) in the imatinib era
    S Bonvalot
    Department of Surgery, Institut Gustave Roussy, 94805, Villejuif, France
    Ann Surg Oncol 13:1596-603. 2006
    ..The objective of this retrospective study was to evaluate the feasibility and benefit of this secondary surgery...
  17. doi request reprint [Surgical news of soft tissue sarcomas, fibromatosis and GIST]
    S Bonvalot
    Institut Gustave Roussy, Departement de Chirurgie, 39, rue Camille Desmoulins, 94805 Villejuif, France
    Bull Cancer 97:645-56. 2010
    ..An ongoing phase III EORTC randomises this secondary surgery after 6 to 12 months of imatinib in responding patients...
  18. ncbi request reprint [Free-flap reconstruction of locally advanced soft tissue sarcomas]
    S Bonvalot
    Departement de Chirurgie Oncologique, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif, France
    Ann Chir 126:308-13. 2001
    ..The aim of this retrospective study was to assess the advantages of free-lap reconstruction in locally advanced soft tissue sarcomas...
  19. doi request reprint [What is new in the local approach of limb sarcomas and desmoid tumours?]
    S Bonvalot
    Comité Sarcomes, Departement de Chirurgie, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif, France
    Cancer Radiother 14:455-9. 2010
    ..Additional study of the molecular determinants of desmoid behaviour is needed to guide treatment...
  20. ncbi request reprint Pressure-suit combined with pelvic stop-flow: a feasibility study in a bovine model
    S Bonvalot
    Department of Surgery, Institut Gustave Roussy, 94805 Villejuif, France
    Eur J Surg Oncol 33:114-8. 2007
    ..Isolated pelvic perfusion exposes tissue to high drug doses and may benefit patients with advanced malignancy. However, leakage is a limit to this technique...
  21. ncbi request reprint Role of computed tomography in the follow-up of hepatic and peritoneal metastases of GIST under imatinib mesylate treatment: a prospective study of 54 patients
    Daniel Vanel
    Department of Radiology, Institut Gustave Roussy, rue Camille Desmoulins, 94800 Villejuif, France
    Eur J Radiol 54:118-23. 2005
    ..To prospectively analyze the evolution of hepatic and peritoneal unresectable metastases from gastrointestinal stromal tumors (GIST) under imatinib mesylate, a new targeted treatment, which induces changes in lesion structure...
  22. doi request reprint Follow-up of hepatic and peritoneal metastases of gastrointestinal tumors (GIST) under Imatinib therapy requires different criteria of radiological evaluation (size is not everything!!!)
    Mylene Mabille
    Department of Radiology, Institut Gustave Roussy, Villejuif, France
    Eur J Radiol 69:204-8. 2009
    ..To define computed tomography (CT) criteria for evaluating the response of patients with gastrointestinal stromal tumors (GIST) who are receiving Imatinib (tyrosine-kinase inhibitor therapy)...
  23. ncbi request reprint [Locally advanced soft-tissue sarcomas. An innovating triad to avoid amputation: isolated limb perfusion, TNFalpha, and free microsurgical flap]
    Michel A Germain
    Departement de Chirurgie Oncologique, Institut Gustave Roussy, 39, rue Camille Desmoulins, F 94805 Villejuif Cedex
    Bull Acad Natl Med 194:51-65; discussion 65-7. 2010
    ..Isolated limb perfusion and free flap reconstruction permitted more extensive tumor excision. Amputation was avoided in 78% of our 37 patients, and early postoperative radiotherapy was possible in 25 cases...
  24. ncbi request reprint Gastrointestinal stromal tumors treated with imatinib: monitoring response with contrast-enhanced sonography
    Nathalie Lassau
    Department of Medical Imaging, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France
    AJR Am J Roentgenol 187:1267-73. 2006
    ..The purpose of this study was to evaluate contrast-enhanced Doppler sonography with perfusion software as a predictor of early tumor response to imatinib (Glivec) in c-kit-positive gastrointestinal stromal tumors (GISTs)...
  25. doi request reprint Hyperthermic isolated limb perfusion in locally advanced soft tissue sarcoma and progressive desmoid-type fibromatosis with TNF 1 mg and melphalan (T1-M HILP) is safe and efficient
    Sylvie Bonvalot
    Department of Surgery, Institut Gustave Roussy, Villejuif Cedex, France
    Ann Surg Oncol 16:3350-7. 2009
    ..The objective of the present study was to confirm these data on a larger sample size of locally advanced or recurrent extremity soft tissue sarcomas with low-dose TNF-alpha...
  26. doi request reprint Phase II study of oral masitinib mesilate in imatinib-naïve patients with locally advanced or metastatic gastro-intestinal stromal tumour (GIST)
    Axel Le Cesne
    Institut Gustave Roussy, Villejuif, France
    Eur J Cancer 46:1344-51. 2010
    ..This phase II study evaluated masitinib as a first-line treatment of advanced GIST...
  27. doi request reprint Feasibility of metronomic oral cyclophosphamide plus prednisolone in elderly patients with inoperable or metastatic soft tissue sarcoma
    Olivier Mir
    Sarcoma Unit, Herault Ward, Department of Medicine, Institut Gustave Roussy, Université Paris 11, 39 rue Camille Desmoulins, Villejuif, France
    Eur J Cancer 47:515-9. 2011
    ..A sizeable population of elderly patients with STS is unfit for conventional doxorubicin- or ifosfamide-based chemotherapy. We assessed the feasibility of metronomic oral cyclophosphamide (CPM) in this population...
  28. doi request reprint Doxorubicin and ifosfamide for high-grade sarcoma during pregnancy
    Olivier Mir
    Department of Medicine, Sarcoma Unit, Herault Ward, Institut Gustave Roussy, Paris Sud University, 39, rue Camille Desmoulins, 94800 Villejuif Cedex, France
    Cancer Chemother Pharmacol 69:357-67. 2012
    ..Doxorubicin and ifosfamide are highly active drugs for the treatment of high-grade sarcomas, but little is known on the optimal management of young patients who develop such malignancies during pregnancy...
  29. doi request reprint Aggressive surgery in retroperitoneal soft tissue sarcoma carried out at high-volume centers is safe and is associated with improved local control
    Sylvie Bonvalot
    Department of Surgery, Institut Gustave Roussy, Villejuif, France
    Ann Surg Oncol 17:1507-14. 2010
    ..We sought to assess morbidity and mortality in primary retroperitoneal soft tissue sarcomas (RSTS) treated by a frontline aggressive surgical approach...
  30. doi request reprint Epithelioid sarcoma: need for a multimodal approach to maximize the chances of curative conservative treatment
    Antonin Levy
    Department of Radiation Oncology, Institut Gustave Roussy, Universite Paris Sud, Villejuif, France
    Ann Surg Oncol 21:269-76. 2014
    ..This study was designed to evaluate the impact of multimodal management on a series of epithelioid sarcoma (ES) patients treated with curative intent...
  31. ncbi request reprint MR imaging in the evaluation of isolated limb perfusion: a prospective study of 18 cases
    Daniel Vanel
    Department of Radiology, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Skeletal Radiol 33:150-6. 2004
    ....
  32. ncbi request reprint [Retroperitoneal sarcomas imaging]
    François J Bidault
    Service de Radiodiagnostic, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex
    Bull Cancer 93:1167-74. 2006
    ..The aim of this article is to expose imaging protocols and useful radiological signs, to show the core biopsy technique for diagnosis, to precise imaging key points before treatment and for survey...
  33. ncbi request reprint [Place and technical aspects of external beam radiation therapy in the treatment of adult soft tissue sarcomas]
    Cécile Le Péchoux
    Departement de Radiotherapie, Institut Gustave Roussy, 94805 Villejuif, France
    Cancer Radiother 10:50-62. 2006
    ..A randomized trial is warranted. Because of its rarity, and the risk of recurrence both local and metastatic, treatment should preferentially be discussed with a multimodality specialized approach...
  34. ncbi request reprint Does adjuvant radiation therapy increase loco-regional control after optimal resection of soft-tissue sarcoma of the extremities?
    K Khanfir
    Department of Radiotherapy, Institut Gustave Roussy, 94805 Villejuif, France
    Eur J Cancer 39:1872-80. 2003
    ....
  35. doi request reprint Conservative en bloc surgery for aggressive angiomyxoma achieves good local control: analysis of 14 patients from a single institution
    Sarah Coppola
    Department of Surgery, Institut Gustave Roussy, Villejuif, France
    Int J Gynecol Cancer 23:540-5. 2013
    ..The purpose of this study was to assess the value of conservative surgery in aggressive angiomyxoma (AA) in our institutional series...
  36. ncbi request reprint [Clinical practice guidelines: 2006 update of recommendations for the radiotherapeutic management of patients with soft tissue sarcoma (sarcoma of the extremity, uterine sarcoma and retroperitoneal sarcoma]
    C Le Pechoux
    Institut Gustave Roussy, Villejuif, France
    Cancer Radiother 10:185-207. 2006
    ..This work is based on the methodology developed in the "Standards, Options and Recommendations" (SOR) project...
  37. doi request reprint [Focus on GIST management]
    M Tardieu
    Institut Gustave Roussy, Departement de Medecine, 39, rue Camille Desmoulins, 94800 Villejuif Cedex, France
    Bull Cancer 97:723-31. 2010
    ....
  38. doi request reprint Spontaneous regression of primary abdominal wall desmoid tumors: more common than previously thought
    Sylvie Bonvalot
    Department of Surgery, Gustave Roussy Institute, Villejuif, France
    Ann Surg Oncol 20:4096-102. 2013
    ..The relevance of the initial observational approach for desmoid tumors (DTs) remains unclear. We investigated a new conservative management treatment for primary abdominal wall DTs...
  39. ncbi request reprint Prognostic factors after surgery of primary resectable gastrointestinal stromal tumours
    T Aparicio
    Department of Medicine, Institut Gustave Roussy, Villejuif, France
    Eur J Surg Oncol 30:1098-103. 2004
    ..To analyse the prognostic factors of gastrointestinal stromal tumours (GIST) after a complete resection of the primary tumour...
  40. ncbi request reprint Prognostic factors in retroperitoneal sarcoma: a multivariate analysis of a series of 165 patients of the French Cancer Center Federation Sarcoma Group
    E Stoeckle
    Department of Surgery, Institut Bergonie, Bordeaux, France
    Cancer 92:359-68. 2001
    ..However, despite progress, surgery alone is rarely curative, and analysis of the causes of failures and of other prognostic factors are warranted to ascertain treatment orientations...
  41. ncbi request reprint Phase II study of ET-743 in advanced soft tissue sarcomas: a European Organisation for the Research and Treatment of Cancer (EORTC) soft tissue and bone sarcoma group trial
    A Le Cesne
    Department of Medicine, Institut Gustave Roussy, 94805 Villejuif Cedex, France
    J Clin Oncol 23:576-84. 2005
    ..5 mg/m(2) as a 24-hour continuous infusion every 3 weeks in patients with pretreated advanced soft tissue sarcoma...
  42. ncbi request reprint Treatment of liver metastases with moderate peritoneal carcinomatosis by hepatectomy and cytoreductive surgery followed by immediate post-operative intraperitoneal chemotherapy: feasibility and preliminary results
    D Elias
    Department of Oncologic Digestive Surgery, Institut Gustave Roussy, Cancer Center Hospital, Villejuif, France
    Hepatogastroenterology 46:360-3. 1999
    ..The purpose of this study is to report tolerance and preliminary results in patients with liver metastases synchronous to moderate PC, treated with hepatectomy, complete cytoreductive surgery, and IPIC...
  43. ncbi request reprint Doppler US with perfusion software and contrast medium injection in the early evaluation of isolated limb perfusion of limb sarcomas: prospective study of 49 cases
    N Lassau
    Department of Medical Imaging, Surgery, Pathology and Medicine, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France
    Ann Oncol 16:1054-60. 2005
    ....
  44. doi request reprint Mapping the literature: role of trabectedin as a new chemotherapy option in advanced pretreated soft tissue sarcoma
    A Le Cesne
    Institut Gustave Roussy, Villejuif, France
    Drugs Today (Barc) 45:403-21. 2009
    ....
  45. ncbi request reprint Imatimid-induced bone marrow necrosis detected on MRI examination and mimicking bone metastases
    D Vanel
    Institut Gustave Roussy, Villejuif, France
    Skeletal Radiol 36:895-8. 2007
    ..Focal bone marrow abnormalities, detected on MRI examinations and mimicking bone metastases in patients who were otherwise responding, should be considered as probable bone marrow necrosis...
  46. doi request reprint Liposarcoma or lipoma: does genetics change classic imaging criteria?
    F Bidault
    Department of Radiology, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France
    Eur J Radiol 72:22-6. 2009
    ..Cytogenetic and molecular genetic analyses contribute to the diagnosis and can be performed at the same time with a core biopsy...
  47. ncbi request reprint p53 status correlates with histopathological response in patients with soft tissue sarcomas treated using isolated limb perfusion with TNF-alpha and melphalan
    J Muret
    Department of AnesthesiaInstitut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Ann Oncol 19:793-800. 2008
    ..The relationship between p53 status and response to TNF-alpha and melphalan in patients undergoing ILP is unknown...
  48. doi request reprint IMRT or conformal radiotherapy for adjuvant treatment of retroperitoneal sarcoma?
    Amaury Paumier
    Department of Radiation Oncology, Institut Gustave Roussy, Villejuif, France
    Radiother Oncol 99:73-8. 2011
    ....
  49. ncbi request reprint [Continued complete remission of Merkel cell carcinoma with in-transit metastasis after treatment with isolated limb perfusion regional chemotherapy]
    C Grandpeix
    Service de Dermatologie, Institut Gustave Roussy, Villejuif, France
    Ann Dermatol Venereol 133:700-3. 2006
    ..Primitive cutaneous neuroendocrine carcinoma or Merkel cell carcinoma is a rare tumor. It may be large since diagnosis is frequently delayed. The usual treatment is extensive surgical removal and radiotherapy...
  50. ncbi request reprint Unusual problems in breast cancer and a rare lung cancer case. Case 2. Aggressive fibromatosis of the chest wall arising near a breast prosthesis
    Kaouthar Khanfir
    Institut Gustave Roussy, Villejuif, France
    J Clin Oncol 21:2216-8. 2003
  51. ncbi request reprint Spermatic cord sarcoma in adults
    O Merimsky
    Department of Medicine, Institut Gustav Roussy, Villejuif, France
    Acta Oncol 38:635-8. 1999
    ..5 months. Surgery was the primary treatment and the best salvage modality. The role of chemotherapy and radiation therapy as true adjuvant or post-salvage-surgery adjunctive treatments remains unclear...
  52. ncbi request reprint [Pulmonary carcinosarcoma with jejunal metastasis: complete response to chemotherapy]
    F Saint-Georges
    Département de médecine adulte, Institut Gustave Roussy, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Rev Pneumol Clin 58:249-52. 2002
    ..This rare case illustrates the potential for jejunal metastasis and complete response to chemotherapy, proven histologically at 33 months...
  53. pmc Attenuation of soft-tissue sarcomas resistance to the cytotoxic action of TNF-α by restoring p53 function
    Jane Muret
    Unité INSERM U753, Institut de Cancerologie Gustave Roussy, Villejuif, France
    PLoS ONE 7:e38808. 2012
    ..Here we tested the ability of TNF-α to directly induce apoptosis of sarcoma cells. In addition, we investigated the impact of p53 in the regulation of such effect...
  54. ncbi request reprint [Treatment of local recurrent melanomas by isolated limb perfusion: value of Doppler ultrasonography]
    P Hochedez
    Service de Dermatologie, Institut Gustave Roussy IGR, 39 rue Camille Desmoulins, 94805 Villejuif, France
    J Radiol 84:597-603. 2003
    ..To assess the effectiveness of Color Doppler Ultrasound (US) in the follow-up of recurrent melanoma of the limbs treated by isolated limb perfusion (ILP)...
  55. pmc High frequency of beta-catenin heterozygous mutations in extra-abdominal fibromatosis: a potential molecular tool for disease management
    J Domont
    Sarcoma Committee, Institut Gustave Roussy, Villejuif, France
    Br J Cancer 102:1032-6. 2010
    ..There are no known molecular biomarkers of local recurrence. We searched for beta-catenin mutations in a European multicentre series of fibromatosis tumours to relate beta-catenin mutational status to disease outcome...
  56. ncbi request reprint [The development of operating tables]
    M A Germain
    Departement de Chirurgie, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex
    Ann Chir 131:162-6. 2006
    ..Introduction of anaesthesia in 1846 and asepsis in 1870 have strongly allowed this development...
  57. ncbi request reprint Management of gastrointestinal stromal tumors in the imatinib era: selected case studies
    Robert S Benjamin
    Sarcoma Medical Oncology, University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA
    Oncologist 11:9-20. 2006
    ..The management of GIST in these cases required a coordinated, multidisciplinary approach involving medical oncologists, diagnostic radiologists, gastroenterologists, surgeons, and pathologists...
  58. ncbi request reprint [Recommendations for the management of GIST patients]
    Jean Yves Blay
    Unité Inserm 590, Centre Leon Berard, 69008 Lyon
    Bull Cancer 92:907-18. 2005
    ..A national consensus meeting was therefore organized in order to identify the optimal management procedures for patients with GIST in localized and advanced stages...
  59. ncbi request reprint [Neoadjuvant chemotherapy in sarcoma]
    Jean Yves Blay
    Hôpital Edouard Herriot et Unité Inserm U590, Centre Leon Berard, 28, rue Laennec, 69008 Lyon
    Bull Cancer 93:1093-8. 2006
    ..In elderly and/or frail patients, conversely, single agent doxorubicin may be the preferred option...
  60. doi request reprint Gastrointestinal stromal tumors: ESMO clinical recommendations for diagnosis, treatment and follow-up
    P G Casali
    Department of Cancer Medicine, Istituto Nazionale dei Tumori, Milan, Italy
    Ann Oncol 19:ii35-8. 2008
  61. doi request reprint Soft tissue sarcomas: ESMO clinical recommendations for diagnosis, treatment and follow-up
    P G Casali
    Department of Cancer Medicine, Istituto Nazionale dei Tumori, Milan, Italy
    Ann Oncol 19:ii89-93. 2008