Oliver Bischof

Summary

Affiliation: Institut Pasteur
Country: France

Publications

  1. ncbi request reprint SUMO is growing senescent
    Oliver Bischof
    Unité d Organisation Nucléaire et Oncogenèse INSERM U579, Institut Pasteur, Paris, France
    Cell Cycle 6:677-81. 2007
  2. ncbi request reprint [A review of cellular senescence: friend or foe of tumorigenesis?]
    Oliver Bischof
    Unité d Organisation Nucléaire et Oncogenèse ONO, INSERM U579, Institut Pasteur, 28, rue du Docteur Roux, 75724 Paris Cedex 15, France
    Med Sci (Paris) 25:153-60. 2009
  3. pmc Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence
    Nadine Martin
    Department of Cell Biology and Infection, Nuclear Organisation and Oncogenesis Laboratory, Institut Pasteur, Paris, France
    EMBO J 31:95-109. 2012
  4. pmc PARP-1 transcriptional activity is regulated by sumoylation upon heat shock
    Nadine Martin
    Department of Cell Biology and Infection, Nuclear Organisation and Oncogenesis Unit, INSERM U579, Institut Pasteur, Paris, France
    EMBO J 28:3534-48. 2009
  5. pmc Human papillomavirus oncoprotein E7 targets the promyelocytic leukemia protein and circumvents cellular senescence via the Rb and p53 tumor suppressor pathways
    Oliver Bischof
    Nuclear Organisation and Oncogenesis Unit, INSERM U579, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Mol Cell Biol 25:1013-24. 2005
  6. ncbi request reprint The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis
    Oliver Bischof
    Nuclear Organisation and Oncogenesis Unit, INSERM U579, Institut Pasteur, 75724 Paris Cedex 15, France
    Mol Cell 22:783-94. 2006
  7. doi request reprint Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells
    Moussa Benhamed
    Institut Pasteur, Nuclear Organisation and Oncogenesis Unit, Department of Cell Biology and Infection, F 75015 Paris, France
    Nat Cell Biol 14:266-75. 2012
  8. pmc Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation
    Hélène Neyret-Kahn
    Institut Pasteur, Laboratory of Nuclear Organization and Oncogenesis, Department of Cell Biology and Infection, F 75015 Paris, France
    Genome Res 23:1563-79. 2013
  9. pmc Deconstructing PML-induced premature senescence
    Oliver Bischof
    Unite de Recombinaison et Expression Genetique, INSERM U 163, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    EMBO J 21:3358-69. 2002

Collaborators

Detail Information

Publications9

  1. ncbi request reprint SUMO is growing senescent
    Oliver Bischof
    Unité d Organisation Nucléaire et Oncogenèse INSERM U579, Institut Pasteur, Paris, France
    Cell Cycle 6:677-81. 2007
    ..Here, we discuss some of the implications for this novel connection and future directions to study in more detail the importance of the SUMO pathway in senescence and tumorigenesis...
  2. ncbi request reprint [A review of cellular senescence: friend or foe of tumorigenesis?]
    Oliver Bischof
    Unité d Organisation Nucléaire et Oncogenèse ONO, INSERM U579, Institut Pasteur, 28, rue du Docteur Roux, 75724 Paris Cedex 15, France
    Med Sci (Paris) 25:153-60. 2009
    ..Here, we take a snapshot of the progress in understanding the causes and consequences of cellular senescence in vitro and in vivo...
  3. pmc Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence
    Nadine Martin
    Department of Cell Biology and Infection, Nuclear Organisation and Oncogenesis Laboratory, Institut Pasteur, Paris, France
    EMBO J 31:95-109. 2012
    ..Collectively, our findings indicate that PML and TBX2 act in an autoregulatory loop to control the effective execution of the senescence program...
  4. pmc PARP-1 transcriptional activity is regulated by sumoylation upon heat shock
    Nadine Martin
    Department of Cell Biology and Infection, Nuclear Organisation and Oncogenesis Unit, INSERM U579, Institut Pasteur, Paris, France
    EMBO J 28:3534-48. 2009
    ..These results, thus, point to a novel mechanism for regulating PARP-1 transcription function, and suggest crosstalk between sumoylation and RNF4-mediated ubiquitination in regulating gene expression in response to heat shock...
  5. pmc Human papillomavirus oncoprotein E7 targets the promyelocytic leukemia protein and circumvents cellular senescence via the Rb and p53 tumor suppressor pathways
    Oliver Bischof
    Nuclear Organisation and Oncogenesis Unit, INSERM U579, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Mol Cell Biol 25:1013-24. 2005
    ..Given the importance of HPV in the pathogenesis of cervical cancer, our results warrant a more detailed analyses of PML in HPV infections...
  6. ncbi request reprint The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis
    Oliver Bischof
    Nuclear Organisation and Oncogenesis Unit, INSERM U579, Institut Pasteur, 75724 Paris Cedex 15, France
    Mol Cell 22:783-94. 2006
    ..Altogether, these data provide the first evidence for a direct role of an E3 SUMO ligase, and by implication of the SUMO pathway, in cellular senescence and apoptosis...
  7. doi request reprint Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells
    Moussa Benhamed
    Institut Pasteur, Nuclear Organisation and Oncogenesis Unit, Department of Cell Biology and Infection, F 75015 Paris, France
    Nat Cell Biol 14:266-75. 2012
    ..Our results suggest that miRNA/AGO2-mediated SA-TGS may contribute to tumour suppression by stably repressing proliferation-promoting genes in premalignant cancer cells...
  8. pmc Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation
    Hélène Neyret-Kahn
    Institut Pasteur, Laboratory of Nuclear Organization and Oncogenesis, Department of Cell Biology and Infection, F 75015 Paris, France
    Genome Res 23:1563-79. 2013
    ....
  9. pmc Deconstructing PML-induced premature senescence
    Oliver Bischof
    Unite de Recombinaison et Expression Genetique, INSERM U 163, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    EMBO J 21:3358-69. 2002
    ..Taken together, our data assign a specific pro-senescent activity to an individual PML isoform that involves p53 activation and is independent from PML nuclear bodies...