Timo Betz

Summary

Affiliation: Institut Curie
Country: France

Publications

  1. pmc Growth cones as soft and weak force generators
    Timo Betz
    Division of Soft Matter Physics, Department of Physics, Universitat Leipzig, Linnestrasse 5, 04103 Leipzig, Germany
    Proc Natl Acad Sci U S A 108:13420-5. 2011
  2. pmc ATP-dependent mechanics of red blood cells
    Timo Betz
    Centre de Recherche, Institut Curie, Unités Mixte de Recherche 168, F 75248 Paris, France
    Proc Natl Acad Sci U S A 106:15320-5. 2009
  3. pmc Stochastic actin polymerization and steady retrograde flow determine growth cone advancement
    Timo Betz
    Division of Soft Matter Physics, Department of Physics, Universitat Leipzig, 04103 Leipzig, Germany
    Biophys J 96:5130-8. 2009
  4. pmc Neurite branch retraction is caused by a threshold-dependent mechanical impact
    Kristian Franze
    Department of Physics, Soft Matter Physics Group, Paul Flechsig Institute of Brain Research, Universitat Leipzig, Leipzig, Germany
    Biophys J 97:1883-90. 2009
  5. ncbi request reprint Optical neuronal guidance
    Allen Ehrlicher
    Lehrstuhl für die Physik weicher Materie, Fakultat fur Physik und Geowissenschaften, Universitat Leipzig, Linnestr 5, Leipzig D 04103, Germany
    Methods Cell Biol 83:495-520. 2007
  6. pmc Mechanical detection of a long-range actin network emanating from a biomimetic cortex
    Matthias Bussonnier
    Institut Curie, Centre de Recherche, Paris, France Université Paris Diderot, Sorbonne Paris Cité, Paris, France Sorbonne Universités, Universite Pierre et Marie Curie, université Paris 06, UMR 168, Paris, France Centre National de la Recherche Scientifique, UMR168, Paris, France
    Biophys J 107:854-62. 2014
  7. pmc Actin polymerization or myosin contraction: two ways to build up cortical tension for symmetry breaking
    Kevin Carvalho
    Centre de Recherche, Institut Curie, Paris 75248, France
    Philos Trans R Soc Lond B Biol Sci 368:20130005. 2013
  8. ncbi request reprint Simultaneous manipulation and detection of living cell membrane dynamics
    Michael Gögler
    Department of Physics, University of Leipzig, Linnestrasse 5, 04103 Leipzig, Germany
    Opt Lett 32:1893-5. 2007
  9. doi request reprint External forces control mitotic spindle positioning
    Jenny Fink
    Institut Curie, CNRS UMR 144, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    Nat Cell Biol 13:771-8. 2011
  10. doi request reprint ESCRT-III assembly and cytokinetic abscission are induced by tension release in the intercellular bridge
    Julie Lafaurie-Janvore
    Institut Curie, CNRS UMR 144, Paris, France
    Science 339:1625-9. 2013

Collaborators

Detail Information

Publications12

  1. pmc Growth cones as soft and weak force generators
    Timo Betz
    Division of Soft Matter Physics, Department of Physics, Universitat Leipzig, Linnestrasse 5, 04103 Leipzig, Germany
    Proc Natl Acad Sci U S A 108:13420-5. 2011
    ..Traction force measurements confirmed these values. Hence, our results indicate that growth cones are particularly soft and weak structures that may be very sensitive to the mechanical properties of their environment...
  2. pmc ATP-dependent mechanics of red blood cells
    Timo Betz
    Centre de Recherche, Institut Curie, Unités Mixte de Recherche 168, F 75248 Paris, France
    Proc Natl Acad Sci U S A 106:15320-5. 2009
    ..4 +/- 0.1 k(B)T, that corresponds to an actively increased effective temperature...
  3. pmc Stochastic actin polymerization and steady retrograde flow determine growth cone advancement
    Timo Betz
    Division of Soft Matter Physics, Department of Physics, Universitat Leipzig, 04103 Leipzig, Germany
    Biophys J 96:5130-8. 2009
    ..This hints at a possible role of noise intensity in determining signal detection sensitivity...
  4. pmc Neurite branch retraction is caused by a threshold-dependent mechanical impact
    Kristian Franze
    Department of Physics, Soft Matter Physics Group, Paul Flechsig Institute of Brain Research, Universitat Leipzig, Leipzig, Germany
    Biophys J 97:1883-90. 2009
    ....
  5. ncbi request reprint Optical neuronal guidance
    Allen Ehrlicher
    Lehrstuhl für die Physik weicher Materie, Fakultat fur Physik und Geowissenschaften, Universitat Leipzig, Linnestr 5, Leipzig D 04103, Germany
    Methods Cell Biol 83:495-520. 2007
    ..Automated tracking and laser micromanipulation of cells. Rev. Sci. Instr. 76, 035105]. Optical guidance may eventually be used alone or with other methods for controlling neurite extension in both research and clinical applications...
  6. pmc Mechanical detection of a long-range actin network emanating from a biomimetic cortex
    Matthias Bussonnier
    Institut Curie, Centre de Recherche, Paris, France Université Paris Diderot, Sorbonne Paris Cité, Paris, France Sorbonne Universités, Universite Pierre et Marie Curie, université Paris 06, UMR 168, Paris, France Centre National de la Recherche Scientifique, UMR168, Paris, France
    Biophys J 107:854-62. 2014
    ..Recent evidence shows that such networks even prevent granule condensation in large cells...
  7. pmc Actin polymerization or myosin contraction: two ways to build up cortical tension for symmetry breaking
    Kevin Carvalho
    Centre de Recherche, Institut Curie, Paris 75248, France
    Philos Trans R Soc Lond B Biol Sci 368:20130005. 2013
    ..Our study provides the groundwork to understanding the physical mechanisms at work during polarization prior to cell shape modifications. ..
  8. ncbi request reprint Simultaneous manipulation and detection of living cell membrane dynamics
    Michael Gögler
    Department of Physics, University of Leipzig, Linnestrasse 5, 04103 Leipzig, Germany
    Opt Lett 32:1893-5. 2007
    ..We investigated the membrane motion at the leading edge of red blood cells in detail and showed that this technique can achieve simultaneous manipulation and detection of cellular edge dynamics with unprecedented precision...
  9. doi request reprint External forces control mitotic spindle positioning
    Jenny Fink
    Institut Curie, CNRS UMR 144, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    Nat Cell Biol 13:771-8. 2011
    ..We propose that cells divide according to cues provided by their mechanical micro-environment, aligning daughter cells with the external force field...
  10. doi request reprint ESCRT-III assembly and cytokinetic abscission are induced by tension release in the intercellular bridge
    Julie Lafaurie-Janvore
    Institut Curie, CNRS UMR 144, Paris, France
    Science 339:1625-9. 2013
    ..This mechanism may allow daughter cells to remain connected until they have settled in their final locations, a process potentially important for tissue organization and morphogenesis...
  11. doi request reprint Quantification of collagen contraction in three-dimensional cell culture
    Katarzyna S Kopanska
    Centre de Recherche, Institut Curie, Paris Cedex 05, France Centre National de la Recherche Scientifique, Paris Cedex 05, France UPMC University Paris VI, Paris, France
    Methods Cell Biol 125:353-72. 2015
    ..doi.org/10.5281/zenodo.10116. This tool provides an automatized technique to measure collagen contraction that can be utilized in different 3D cellular systems. ..
  12. ncbi request reprint Neuronal growth: a bistable stochastic process
    Timo Betz
    Institute of Soft Matter Physics, Linnestrasse 5, 04109 Leipzig, Germany
    Phys Rev Lett 96:098103. 2006
    ..An analysis of growth cone motility confirms the model, and predicts that linear changes of the bistable potential, as known from stochastic filtering, result in directed growth cone translocation...