- Transcriptional control of stem cell maintenance in the Drosophila intestineAllison J Bardin
Institut Pasteur, CNRS URA2578, 75724 Paris Cedex 15, France
Development 137:705-14. 2010..We propose that Daughterless-dependent bHLH activity is important for the ISC fate and that E(spl)-C factors inhibit this activity to promote differentiation...
- Distinct levels of Notch activity for commitment and terminal differentiation of stem cells in the adult fly intestineCarolina N Perdigoto
Institut Pasteur, Developmental Biology Department, F 75015 Paris, France
Development 138:4585-95. 2011..Our work suggests that a commitment requirement for high-level Notch activity safeguards the stem cells from loss through differentiation, revealing a novel role for the importance of Notch signaling levels in this system...