George M Bahr

Summary

Affiliation: Institut Pasteur de Lille
Country: France

Publications

  1. ncbi Human chemokine receptors CCR5, CCR3 and CCR2B share common polarity motif in the first extracellular loop with other human G-protein coupled receptors implications for HIV-1 coreceptor function
    R Efremov
    M M Shemyakin, Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
    Eur J Biochem 263:746-56. 1999
  2. pmc Selective regulation of human immunodeficiency virus-infected CD4(+) lymphocytes by a synthetic immunomodulator leads to potent virus suppression in vitro and in hu-PBL-SCID mice
    G M Bahr
    Laboratoire d Immunologie Moleculaire de l Infection et de l Inflammation, Institut Pasteur de Lille, France
    J Virol 75:6941-52. 2001
  3. ncbi Non-specific immunotherapy of HIV-1 infection: potential use of the synthetic immunodulator murabutide
    George M Bahr
    Laboratory of Molecular Immunology of Infection and Inflammation, Institut Pasteur de Lille, 1 rue du Professeur Calmette, BP 245, 59019 Lille Cedex, France
    J Antimicrob Chemother 51:5-8. 2003
  4. pmc Discordant effects of interleukin-2 on viral and immune parameters in human immunodeficiency virus-1-infected monocyte-derived mature dendritic cells
    G M Bahr
    Laboratoire d Immunologie Moleculaire de l Infection et de l Inflammation, Institut Pasteur de Lille, Lille, France
    Clin Exp Immunol 132:289-96. 2003
  5. ncbi Clinical and immunological effects of a 6 week immunotherapy cycle with murabutide in HIV-1 patients with unsuccessful long-term antiretroviral treatment
    George M Bahr
    Laboratory of Molecular Immunology of Infection and Inflammation, Pasteur Institute of Lille, 1 rue du Professeur Calmette, BP 245, 59019 Lille Cedex, France
    J Antimicrob Chemother 51:1377-88. 2003
  6. ncbi Clinical tolerance and immunologic effects after single or repeated administrations of the synthetic immunomodulator murabutide in HIV-1-infected patients
    Corinne Amiel
    Infectious Disease Department of Tourcoing Hospital, Northern AIDS Reference Center, Lille, France
    J Acquir Immune Defic Syndr 30:294-305. 2002
  7. ncbi Differentially expressed genes in HIV-1-infected macrophages following treatment with the virus-suppressive immunomodulator murabutide
    Marie José Truong
    Laboratory of Molecular Immunology of Infection and Inflammation, Pasteur Institute in Lille, 1 rue du Pr Calmette, BP 245, Lille Cedex 59019, France
    Virus Res 99:25-33. 2004
  8. ncbi A phase I study of a six-week cycle of immunotherapy with Murabutide in HIV-1 patients naive to antiretrovirals
    Xavier De La Tribonniere
    Department of Infectious Diseases, Tourcoing Hospital Center, Tourcoing, France
    Med Sci Monit 9:PI43-50. 2003

Collaborators

  • Y Mouton
  • Y Yazdanpanah
  • L Bocket
  • C Cocude
  • Xavier De La Tribonniere
  • Corinne Amiel
  • Marie José Truong
  • Vincent Vidal
  • Edith Darcissac
  • R Efremov
  • Véronique Delsart
  • Clothilde Fontier
  • Daouda Sissoko
  • Jo lle Dewulf
  • Youcef Douadi
  • G Vergoten
  • A Capron
  • J Zeng
  • O Grau
  • M J Truong
  • E C Darcissac
  • C Debard

Detail Information

Publications8

  1. ncbi Human chemokine receptors CCR5, CCR3 and CCR2B share common polarity motif in the first extracellular loop with other human G-protein coupled receptors implications for HIV-1 coreceptor function
    R Efremov
    M M Shemyakin, Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
    Eur J Biochem 263:746-56. 1999
    ..The potential biological significance of the identified structural motif shared by the human CCR5, CCR3, CCR2B and other GPCRs is discussed...
  2. pmc Selective regulation of human immunodeficiency virus-infected CD4(+) lymphocytes by a synthetic immunomodulator leads to potent virus suppression in vitro and in hu-PBL-SCID mice
    G M Bahr
    Laboratoire d Immunologie Moleculaire de l Infection et de l Inflammation, Institut Pasteur de Lille, France
    J Virol 75:6941-52. 2001
    ....
  3. ncbi Non-specific immunotherapy of HIV-1 infection: potential use of the synthetic immunodulator murabutide
    George M Bahr
    Laboratory of Molecular Immunology of Infection and Inflammation, Institut Pasteur de Lille, 1 rue du Professeur Calmette, BP 245, 59019 Lille Cedex, France
    J Antimicrob Chemother 51:5-8. 2003
  4. pmc Discordant effects of interleukin-2 on viral and immune parameters in human immunodeficiency virus-1-infected monocyte-derived mature dendritic cells
    G M Bahr
    Laboratoire d Immunologie Moleculaire de l Infection et de l Inflammation, Institut Pasteur de Lille, Lille, France
    Clin Exp Immunol 132:289-96. 2003
    ..Taken together, these findings point to a role for IL-2 in inducing virus purging from dendritic cell reservoirs but indicate no relevant potential of the cytokine in restoring defective elements of innate immunity in HIV infection...
  5. ncbi Clinical and immunological effects of a 6 week immunotherapy cycle with murabutide in HIV-1 patients with unsuccessful long-term antiretroviral treatment
    George M Bahr
    Laboratory of Molecular Immunology of Infection and Inflammation, Pasteur Institute of Lille, 1 rue du Professeur Calmette, BP 245, 59019 Lille Cedex, France
    J Antimicrob Chemother 51:1377-88. 2003
    ..These results warrant further evaluation of extended periods or cycles of murabutide immunotherapy as adjunct to HAART...
  6. ncbi Clinical tolerance and immunologic effects after single or repeated administrations of the synthetic immunomodulator murabutide in HIV-1-infected patients
    Corinne Amiel
    Infectious Disease Department of Tourcoing Hospital, Northern AIDS Reference Center, Lille, France
    J Acquir Immune Defic Syndr 30:294-305. 2002
    ..These encouraging results warrant further evaluation of longer periods or cycles of immunotherapy with Murabutide in HIV-infected subjects...
  7. ncbi Differentially expressed genes in HIV-1-infected macrophages following treatment with the virus-suppressive immunomodulator murabutide
    Marie José Truong
    Laboratory of Molecular Immunology of Infection and Inflammation, Pasteur Institute in Lille, 1 rue du Pr Calmette, BP 245, Lille Cedex 59019, France
    Virus Res 99:25-33. 2004
    ..Furthermore, our findings suggest the potential implication of additional transcription factors and metal-binding proteins in mediating the inhibitory effect of murabutide on virus transcription...
  8. ncbi A phase I study of a six-week cycle of immunotherapy with Murabutide in HIV-1 patients naive to antiretrovirals
    Xavier De La Tribonniere
    Department of Infectious Diseases, Tourcoing Hospital Center, Tourcoing, France
    Med Sci Monit 9:PI43-50. 2003
    ..000 copies/ml...