R Arriagada

Summary

Affiliation: Institut Gustave Roussy
Country: France

Publications

  1. ncbi request reprint Randomized trial of adjuvant ovarian suppression in 926 premenopausal patients with early breast cancer treated with adjuvant chemotherapy
    R Arriagada
    Institut Gustave Roussy, Bureau 607 A, 1, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Ann Oncol 16:389-96. 2005
  2. ncbi request reprint Results of two randomized trials evaluating adjuvant anthracycline-based chemotherapy in 1146 patients with early breast cancer
    Rodrigo Arriagada
    Institut Gustave Roussy, Villejuif, France
    Acta Oncol 44:458-66. 2005
  3. ncbi request reprint Twenty-five years of follow-up in patients with operable breast carcinoma: correlation between clinicopathologic factors and the risk of death in each 5-year period
    Rodrigo Arriagada
    Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France
    Cancer 106:743-50. 2006
  4. ncbi request reprint Patterns of failure in a randomized trial of adjuvant chemotherapy in postmenopausal patients with early breast cancer treated with tamoxifen
    R Arriagada
    Institut Gustave Roussy, Villejuif, France
    Ann Oncol 13:1378-86. 2002
  5. ncbi request reprint Predictive factors for local recurrence in 2006 patients with surgically resected small breast cancer
    R Arriagada
    Institut Gustave Roussy IGR, Villejuif, France
    Ann Oncol 13:1404-13. 2002
  6. ncbi request reprint Controlled clinical trial of prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission
    A Laplanche
    Département de Biostatistique et d Epidémiologie, Institut Gustave Roussy, Villejuif, France
    Lung Cancer 21:193-201. 1998
  7. ncbi request reprint Late local recurrences in a randomised trial comparing conservative treatment with total mastectomy in early breast cancer patients
    R Arriagada
    Institut Gustave Roussy, Villejuif, France
    Ann Oncol 14:1617-22. 2003
  8. ncbi request reprint Breast cancer molecular subclassification and estrogen receptor expression to predict efficacy of adjuvant anthracyclines-based chemotherapy: a biomarker study from two randomized trials
    R Conforti
    Translational Research Unit, Unité Propre de Recherche de l Enseignement Supérieur, équipe d accueil 03535, Villejuif, France
    Ann Oncol 18:1477-83. 2007
  9. pmc Competing risks determining event-free survival in early breast cancer
    R Arriagada
    Institut Gustave Roussy, Villejuif, France
    Br J Cancer 66:951-7. 1992
  10. doi request reprint Standard-dose versus higher-dose prophylactic cranial irradiation (PCI) in patients with limited-stage small-cell lung cancer in complete remission after chemotherapy and thoracic radiotherapy (PCI 99-01, EORTC 22003-08004, RTOG 0212, and IFCT 99-01): a r
    Cécile Le Péchoux
    Radiotherapy Department, Institut Gustave Roussy, Villejuif, France
    Lancet Oncol 10:467-74. 2009

Detail Information

Publications42

  1. ncbi request reprint Randomized trial of adjuvant ovarian suppression in 926 premenopausal patients with early breast cancer treated with adjuvant chemotherapy
    R Arriagada
    Institut Gustave Roussy, Bureau 607 A, 1, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    Ann Oncol 16:389-96. 2005
    ..The aim of this multicenter trial was to evaluate the role of ovarian suppression in patients with early breast cancer previously treated with local surgery and adjuvant chemotherapy...
  2. ncbi request reprint Results of two randomized trials evaluating adjuvant anthracycline-based chemotherapy in 1146 patients with early breast cancer
    Rodrigo Arriagada
    Institut Gustave Roussy, Villejuif, France
    Acta Oncol 44:458-66. 2005
    ..Adjuvant anthracycline-based chemotherapy yielded a significant benefit for DFS by lowering the risk of distant metastases. After up to 10 years of follow-up, deferring radiotherapy after chemotherapy did not compromise local control...
  3. ncbi request reprint Twenty-five years of follow-up in patients with operable breast carcinoma: correlation between clinicopathologic factors and the risk of death in each 5-year period
    Rodrigo Arriagada
    Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France
    Cancer 106:743-50. 2006
    ..The objective of this study was to assess the effect of prognostic factors on the risk of death in patients with breast carcinoma over a long follow-up...
  4. ncbi request reprint Patterns of failure in a randomized trial of adjuvant chemotherapy in postmenopausal patients with early breast cancer treated with tamoxifen
    R Arriagada
    Institut Gustave Roussy, Villejuif, France
    Ann Oncol 13:1378-86. 2002
    ..We studied the effect of adjuvant anthracycline-based chemotherapy in postmenopausal patients with resected early breast cancer treated with adjuvant tamoxifen...
  5. ncbi request reprint Predictive factors for local recurrence in 2006 patients with surgically resected small breast cancer
    R Arriagada
    Institut Gustave Roussy IGR, Villejuif, France
    Ann Oncol 13:1404-13. 2002
    ..This study investigates whether factors predictive of local recurrence differ between patients treated with conservative or radical surgery...
  6. ncbi request reprint Controlled clinical trial of prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission
    A Laplanche
    Département de Biostatistique et d Epidémiologie, Institut Gustave Roussy, Villejuif, France
    Lung Cancer 21:193-201. 1998
    ..In conclusion, in this study, which had to be closed prematurely, no significant difference was found in terms of the incidence of brain metastases nor in survival...
  7. ncbi request reprint Late local recurrences in a randomised trial comparing conservative treatment with total mastectomy in early breast cancer patients
    R Arriagada
    Institut Gustave Roussy, Villejuif, France
    Ann Oncol 14:1617-22. 2003
    ..A randomised trial was conducted comparing wide lumpectomy and breast irradiation with modified radical mastectomy. As the follow-up was long (mean duration 22 years), we analysed the variation in the effect of treatment over time...
  8. ncbi request reprint Breast cancer molecular subclassification and estrogen receptor expression to predict efficacy of adjuvant anthracyclines-based chemotherapy: a biomarker study from two randomized trials
    R Conforti
    Translational Research Unit, Unité Propre de Recherche de l Enseignement Supérieur, équipe d accueil 03535, Villejuif, France
    Ann Oncol 18:1477-83. 2007
    ..The purpose of this study was to determine the predictive value of breast cancer molecular subclassification regarding the benefit of adjuvant anthracycline-based chemotherapy...
  9. pmc Competing risks determining event-free survival in early breast cancer
    R Arriagada
    Institut Gustave Roussy, Villejuif, France
    Br J Cancer 66:951-7. 1992
    ..It is thus useful for the description of the natural history of breast cancer as well as other diseases...
  10. doi request reprint Standard-dose versus higher-dose prophylactic cranial irradiation (PCI) in patients with limited-stage small-cell lung cancer in complete remission after chemotherapy and thoracic radiotherapy (PCI 99-01, EORTC 22003-08004, RTOG 0212, and IFCT 99-01): a r
    Cécile Le Péchoux
    Radiotherapy Department, Institut Gustave Roussy, Villejuif, France
    Lancet Oncol 10:467-74. 2009
    ..A meta-analysis suggested that the incidence of brain metastases might be reduced with higher PCI doses. This randomised clinical trial compared the effect of standard versus higher PCI doses on the incidence of brain metastases...
  11. pmc Impact of tumour size on axillary involvement and distant dissemination in breast cancer
    S Koscielny
    Department of Clinical and Translational Research, Institut Gustave Roussy, Villejuif, France
    Br J Cancer 101:902-7. 2009
    ..Tumour size and nodal involvement are the two main prognostic factors in breast cancer (BC). Their impact on the natural history of BC is not fully captured by analyses that ignore their quantitative nature...
  12. pmc Clinical neurological outcome and quality of life among patients with limited small-cell cancer treated with two different doses of prophylactic cranial irradiation in the intergroup phase III trial (PCI99-01, EORTC 22003-08004, RTOG 0212 and IFCT 99-01)
    C Le Pechoux
    Radiation Oncology Department, Institut Gustave Roussy, Villejuif, France
    Ann Oncol 22:1154-63. 2011
    ..As concerns about neurotoxicity were a major issue surrounding PCI, we report here midterm and long-term repeated evaluation of neurocognitive functions and quality of life (QoL)...
  13. doi request reprint Long-term mortality in a cohort study of 6,800 French breast cancer patients treated between 1954 and 1983
    Houda Boukheris
    National Institute of Health and Medical Research, Villejuif, France
    Acta Oncol 47:1122-32. 2008
    ..To investigate the impact of initial tumour characteristics and loco-regional radiotherapy on long-term survival following breast cancer diagnosis...
  14. pmc Relation of risk of contralateral breast cancer to the interval since the first primary tumour
    C Rubino
    Institut National de la Sante et de la Recherche Medicale INSERM, Unit 605, Villejuif Cedex 94805, France
    Br J Cancer 102:213-9. 2010
    ..There is no consensus on how to separate contralateral breast cancer (CBC) occurring as distant spread of the primary breast cancer (BC) from an independent CBC...
  15. ncbi request reprint Prognostic factors for death after an isolated local recurrence in patients with early-stage breast carcinoma
    Monique G Le
    INSERM Unit 521, Institut Gustave Roussy, Villejuif, France
    Cancer 94:2813-20. 2002
    ..The authors analyzed the outcome of patients with early-stage breast carcinoma after an isolated local recurrence, taking into account initial tumor characteristics and the type of initial treatment and local salvage treatment...
  16. doi request reprint CXCR4 expression in early breast cancer and risk of distant recurrence
    Fabrice Andre
    Breast Medical Oncology Unit, Department of Radiation Therapy, Department of Pathology and Translational Research Unit UPRES EA03535, Institut Gustave Roussy, University of Paris XI, Villejuif, France
    Oncologist 14:1182-8. 2009
    ..e., liver, lung, brain, and bone)...
  17. ncbi request reprint Breast radiotherapy as part of loco-regional treatments in stage IV breast cancer patients with oligometastatic disease
    Céline Bourgier
    Department of Radiation Oncology, Institut Gustave Roussy, Villejuif, France
    Radiother Oncol 96:199-203. 2010
    ..Local treatments seem to improve metastasis progression-free survival (MPFS) and overall survival (OS) when added to systemic therapies in stage IV breast cancer...
  18. ncbi request reprint Dermal lymphatic emboli in inflammatory and noninflammatory breast cancer: a French-Tunisian joint study in 337 patients
    Monique G Le
    Institut Gustave Roussy, Villejuif, France
    Clin Breast Cancer 6:439-45. 2005
    ..We studied whether dermal lymphatic emboli (DLE) add independent prognostic information to the clinical definition of inflammatory breast cancer (IBC)...
  19. doi request reprint Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer
    Anne Auperin
    Unit of Biostatistics and Epidemiology, Institut Gustave Roussy, 94805 Villejuif Cedex, France
    J Clin Oncol 28:2181-90. 2010
    ..The NSCLC Collaborative Group performed a meta-analysis of randomized trials directly comparing concomitant versus sequential radiochemotherapy...
  20. ncbi request reprint Comparison of dose contribution to normal pelvic tissues among conventional, conformal and intensity-modulated radiotherapy techniques in prostate cancer
    Yungan Tao
    Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France
    Acta Oncol 47:442-50. 2008
    ..A long-term follow-up will be needed to evaluate potential late treatment complications related to the use of IMRT and the low or moderate irradiation dose level obtained in the pelvis and in the whole body...
  21. ncbi request reprint Should adjuvant chemotherapy become standard treatment in all patients with resected non-small-cell lung cancer?
    Thierry Le Chevalier
    Institut Gustave Roussy, Faculte de Medecine Paris Sud, 94800 Villejuif, France
    Lancet Oncol 6:182-4. 2005
    ..In this debate, Thierry Le Chevalier and colleagues and Giorgio Scagliotti present opposing arguments for whether this approach should be considered standard...
  22. ncbi request reprint Prophylactic cranial irradiation in small cell lung cancer
    Cécile Le Péchoux
    Department of Radiotherapy, Institut Gustave Roussy, Villejuif 94805, France
    Hematol Oncol Clin North Am 18:355-72. 2004
  23. doi request reprint Long-term results of the international adjuvant lung cancer trial evaluating adjuvant Cisplatin-based chemotherapy in resected lung cancer
    Rodrigo Arriagada
    Institut Gustave Roussy, rue Camille Desmoulins, Villejuif 94800, France
    J Clin Oncol 28:35-42. 2010
    ....
  24. ncbi request reprint Concomitant radio-chemotherapy based on platin compounds in patients with locally advanced non-small cell lung cancer (NSCLC): a meta-analysis of individual data from 1764 patients
    A Auperin
    Unit of Biostatistics and Epidemiology, Radiation Oncology and Medicine, Institut Gustave Roussy, Villejuif, France
    Ann Oncol 17:473-83. 2006
    ..Despite several randomised trials comparing radiotherapy alone with concomitant radio-chemotherapy in patients with locally advanced non-small cell lung cancer (NSCLC), it is not clear whether the addition of chemotherapy improves survival...
  25. ncbi request reprint Are risk factors for breast cancer similar in women with inflammatory breast cancer and in those with non-inflammatory breast cancer?
    Monique G Le
    Institut Gustave Roussy IGR, Villejuif, France
    Breast 15:355-62. 2006
    ..The study was performed in two centers: one French including 49 IBC patients and 140 non-IBC and another Tunisian including 97 IBC and 139 non-IBC. Unconditional logistic regression was used for the analyses...
  26. doi request reprint Interfractional set-up errors evaluation by daily electronic portal imaging of IMRT in head and neck cancer patients
    Berrin Pehlivan
    Department of Radiation Oncology, Institut Gustave Roussy, Villejuif, France
    Acta Oncol 48:440-5. 2009
    ..We aimed to evaluate whether a daily PI is worthwhile and we derived the Planning Target Volume (PTV) margins from the estimation of systematic and random errors...
  27. ncbi request reprint Patterns of failure after prophylactic cranial irradiation in small-cell lung cancer: analysis of 505 randomized patients
    R Arriagada
    Institut Gustave Roussy, Villejuif, France
    Ann Oncol 13:748-54. 2002
    ..The current analysis aimed to evaluate PCI effects on patterns of failure in this patient category...
  28. doi request reprint Oral cavity squamous cell carcinoma in 260 patients aged 80years or more
    Cecile Ortholan
    Department of Radiotherapy, Centre Antoine Lacassagne, Nice, France
    Radiother Oncol 93:516-23. 2009
    ..We report the experience of two French cancer centers in the treatment of oral cavity squamous cell carcinoma (SCC) in patients aged 80 years...
  29. ncbi request reprint Radiotherapy for breast cancer
    Rodrigo Arriagada
    N Engl J Med 346:862-4. 2002
  30. doi request reprint Predicting distant dissemination in patients with early breast cancer
    Rodrigo Arriagada
    Karolinska Institutet, Stockholm, Sweden
    Acta Oncol 47:1113-21. 2008
    ....
  31. doi request reprint Increased risk of recurrence after hormone replacement therapy in breast cancer survivors
    Lars Holmberg
    Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
    J Natl Cancer Inst 100:475-82. 2008
    ..We present results after extended follow-up...
  32. ncbi request reprint Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer
    Rodrigo Arriagada
    Instituto de Radiomedicina, Santiago, Chile
    N Engl J Med 350:351-60. 2004
    ..On the basis of a previous meta-analysis, the International Adjuvant Lung Cancer Trial was designed to evaluate the effect of cisplatin-based adjuvant chemotherapy on survival after complete resection of non-small-cell lung cancer...
  33. ncbi request reprint Resected non-small cell lung cancer: need for adjuvant lymph node treatment? From hope to reality
    Rodrigo Arriagada
    Instituto de Radiomedicina IRAM, Américo Vespucio Norte 1314, Vitacura, Santiago, Chile
    Lung Cancer 42:S57-64. 2003
    ..We discuss here the available worldwide information on this subject. There is an urgent need for new trials in this topic...
  34. ncbi request reprint Choroid metastases: clinical features and treatments in 123 patients
    Isabelle d'Abbadie
    Ophthalmology Unit, Institut Gustave Roussy, Villejuif Cedex, France
    Cancer 98:1232-8. 2003
    ..The current study was performed to analyze the effects of radiotherapy and chemotherapy on visual improvement in patients with choroid metastases (CM), and to determine the clinical factors potentially related to the risk of death...
  35. ncbi request reprint Early breast cancer: adjuvant chemotherapy or radiotherapy, or both?
    Rodrigo Arriagada
    Acta Oncol 45:514-6. 2006
  36. ncbi request reprint Prophylactic cranial irradiation in small cell lung cancer
    Eugenio F Vinés
    Instituto de Radiomedicina IRAM, Santiago, Chile
    Semin Oncol 30:38-46. 2003
    ..A recent meta-analysis including almost 1,000 randomized patients confirmed an improvement in overall survival. We discuss here the different aspects of this preventive treatment in a potentially curable disease...
  37. ncbi request reprint Number of positive axillary lymph nodes and post-mastectomy radiotherapy effect in breast cancer patients
    Rodrigo Arriagada
    Radiother Oncol 84:102-3; discussion 103-4; author reply 104-5. 2007
  38. ncbi request reprint Effect of radiation dose on local control in breast cancer
    Rodrigo Arriagada
    Radiother Oncol 86:285-6; author reply 286. 2008
  39. ncbi request reprint The natural history of breast carcinoma in patients with > or = 10 metastatic axillary lymph nodes before and after the advent of adjuvant therapy: a multiinstitutional retrospective study
    Alberto J Montero
    Division of Cancer Medicine, Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 104:229-35. 2005
    ..The purpose of the current study, performed retrospectively, was to characterize the natural history of this subset of patients, both before and after the advent of adjuvant anthracycline-based chemotherapy and tamoxifen...
  40. ncbi request reprint Radiation dose escalation in non-small cell carcinoma of the lung
    Rodrigo Arriagada
    University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Semin Radiat Oncol 14:287-91. 2004
  41. doi request reprint Hypofractionation in radiotherapy for breast cancer
    Harry Bartelink
    Netherlands Cancer Institute, 1066CX Amsterdam, Netherlands
    Lancet 371:1050-2. 2008
  42. ncbi request reprint Enhanced local control by radiation boost in breast cancer: back side of the coin?
    Céline Bourgier
    J Clin Oncol 25:5841-3; author reply 5844-5. 2007