Research Topics
| Laurence ArbibeSummaryAffiliation: Institut Pasteur Country: France Publications
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Detail Information
Publications
An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responsesLaurence Arbibe
Unite de Pathogenie Microbienne Moleculaire, Institut Pasteur, F75724 Paris Cedex 15, France
Nat Immunol 8:47-56. 2007..S. flexneri has thus evolved the capacity to precisely modulate host cell epigenetic 'information' as a strategy for repressing innate immunity...
Epigenetic regulation of host response to LPS: causing tolerance while avoiding Toll errancyLaurence Arbibe
Unité de Pathogénie Microbienne Moléculaire and Unité INSERM 786, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France
Cell Host Microbe 1:244-6. 2007..In a recent paper, Foster et al. (2007) demonstrate that this subtle balance is established and imprinted via epigenetic regulation...
Immune subversion by chromatin manipulation: a 'new face' of host-bacterial pathogen interactionLaurence Arbibe
Unite de Pathogenie Microbienne Moleculaire, INSERM U389, Département de Biologie Cellulaire et Infection, Institut Pasteur, 75015 Paris, France
Cell Microbiol 10:1582-90. 2008..This emerging field should strongly influence our understanding of chromatin regulation at interphase nucleus and may provide invaluable openings to the control of immune gene expression in inflammatory and infectious diseases...
Calpain activation by the Shigella flexneri effector VirA regulates key steps in the formation and life of the bacterium's epithelial nicheJean Bergounioux
Unite de Pathogenie Microbienne Moleculaire, Département de Biologie Cellulaire et Infection, Institut Pasteur, Paris, France
Cell Host Microbe 11:240-52. 2012....
[Shigella flexneri modulates host cell epigenetic information as a strategy to shape the transcriptional response]Laurence Arbibe
Med Sci (Paris) 23:238-40. 2007
PtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infectionCaroline Pendaries
, CPTP, , , Toulouse, France
EMBO J 25:1024-34. 2006..Thus, S. flexneri parasitism is shedding light onto a new mechanism of PI 3-kinase/Akt activation via PtdIns5P production that plays an important role in host cell responses such as survival...
NF-kappaB regulates spatial memory formation and synaptic plasticity through protein kinase A/CREB signalingBarbara Kaltschmidt
Universitat Witten Herdecke, Institut fur Neurobiochemie, Stockumer Strasse 10, D 58448 Witten, Germany
Mol Cell Biol 26:2936-46. 2006....
SpvC is a Salmonella effector with phosphothreonine lyase activity on host mitogen-activated protein kinasesPiotr Mazurkiewicz
Centre for Molecular Microbiology and Infection, Imperial College London, Armstrong Road, London SW7 2AZ, UK
Mol Microbiol 67:1371-83. 2008..A Salmonella strain expressing spvC from a plasmid downregulated cytokine release from infected cells...
