Genomes and Genes


Philippe Amouyel


Affiliation: Institut Pasteur de Lille
Country: France


  1. Dauchet L, Hulo S, Cherot Kornobis N, Matran R, Amouyel P, Edme J, et al. Short-term exposure to air pollution: Associations with lung function and inflammatory markers in non-smoking, healthy adults. Environ Int. 2018;121:610-619 pubmed publisher
    ..If these exploratory results are confirmed, this could suggest that even moderate levels of air pollution could have an impact on respiratory health on the general population, and not solely on susceptible individuals. ..
  2. Meroufel D, Ouhaïbi Djellouli H, Médiène Benchekor S, Hermant X, Grenier Boley B, Lardjam Hetraf S, et al. Examination of the brain natriuretic peptide rs198389 single-nucleotide polymorphism on type 2 diabetes mellitus and related phenotypes in an Algerian population. Gene. 2015;567:159-63 pubmed publisher
    ..05) and a lower homeostatic model assessment insulin resistance index (p=0.05) in non-diabetic individuals. The NPPB rs198389 SNP might modulate fasting insulin levels in an Algerian population. ..
  3. Spear R, Boytard L, Blervaque R, Chwastyniak M, Hot D, Vanhoutte J, et al. Adventitial Tertiary Lymphoid Organs as Potential Source of MicroRNA Biomarkers for Abdominal Aortic Aneurysm. Int J Mol Sci. 2015;16:11276-93 pubmed publisher
    ..Further investigations will be required to evaluate their targets in order to better understand AAA pathophysiology. ..
  4. Gyberg V, De Bacquer D, De Backer G, Jennings C, Kotseva K, Mellbin L, et al. Patients with coronary artery disease and diabetes need improved management: a report from the EUROASPIRE IV survey: a registry from the EuroObservational Research Programme of the European Society of Cardiology. Cardiovasc Diabetol. 2015;14:133 pubmed publisher
    ..Despite advances in patient management there is further potential to improve both the detection and management of patients with diabetes and coronary artery disease. ..
  5. Quach A, Giovannelli J, Chérot Kornobis N, Ciuchete A, Clément G, Matran R, et al. Prevalence and underdiagnosis of airway obstruction among middle-aged adults in northern France: The ELISABET study 2011-2013. Respir Med. 2015;109:1553-61 pubmed publisher
    ..5 to 16.0%, depending on the centre and definition used. The high underdiagnosis rate observed here suggests that greater efforts should be made to identify individuals presenting with the symptoms and/or risk factors associated with AO. ..
  6. Cherot Kornobis N, Hulo S, Giovannelli J, de Broucker V, Matran R, Amouyel P, et al. Exhaled breath NOx levels in a middle-aged adults population-based study: reference values and association with the smoking status. Respir Med. 2018;137:134-140 pubmed publisher
    ..3%). This population-based study has provided the distribution and the upper limit reference value of a nitrosative stress biomarker (NOx) in EBC of middle aged, healthy adults. EBC NOx levels were not associated with smoking status. ..
  7. Ouhaibi Djellouli H, Médiène Benchekor S, Lardjam Hetraf S, Hamani Medjaoui I, Meroufel D, Boulenouar H, et al. The TCF7L2 rs7903146 polymorphism, dietary intakes and type 2 diabetes risk in an Algerian population. BMC Genet. 2014;15:134 pubmed publisher
    ..This association was further strengthened by a high dessert intake, suggesting that gene-diet interactions increase the T2D risk. ..